Gene Symbol | ZBTB7B |
Entrez Gene ID | 51043 |
Full Name | zinc finger and BTB domain containing 7B |
Synonyms | CKROX,THPOK,ZBTB15,ZFP-67,ZFP67,ZNF857B,c-KROX,hcKROX |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]. |
Disorder MIM: |