Gene Symbol | MBL2 |
Entrez Gene ID | 4153 |
Full Name | mannose binding lectin 2 |
Synonyms | COLEC1,HSMBPC,MBL,MBL2D,MBP,MBP-C,MBP1,MBPD |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | {Chronic infections, due to MBL deficiency}, 614372 (3) |