TBC1D3B cDNA ORF clone, Homo sapiens(human)

The following TBC1D3B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TBC1D3B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu16063 NM_001001417.6
Latest version!
Homo sapiens TBC1 domain family member 3B (TBC1D3B), mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$189.50-$265.30
$379.00
OHu50391 XM_005257980.4
Latest version!
Homo sapiens TBC1 domain family member 3B (TBC1D3B), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $307.30
$439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu16063
    Clone ID Related Accession (Same CDS sequence) NM_001001417.6
    Accession Version NM_001001417.6 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1650bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-05-03
    Organism Homo sapiens(human)
    Product TBC1 domain family member 3B
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC243829.3. On Apr 16, 2014 this sequence version replaced NM_001001417.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK292257.1, AK225985.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGGACGTGG TAGAGGTCGC GGGTAGTTGG TGGGCACAAG AGCGAGAGGA CATCATTATG 
    AAATACGAAA AGGGACACCG AGCTGGGCTG CCAGAGGACA AGGGGCCTAA GCCTTTTCGA
    AGCTACAACA ACAACGTCGA TCATTTGGGG ATTGTACATG AGACGGAGCT GCCTCCTCTG
    ACTGCGCGGG AGGCGAAGCA AATTCGGCGG GAGATCAGCC GAAAGAGCAA GTGGGTGGAT
    ATGCTGGGAG ACTGGGAGAA ATACAAAAGC AGCAGAAAGC TCATAGATCG AGCGTACAAG
    GGAATGCCCA TGAACATCCG GGGCCCGATG TGGTCAGTCC TCCTGAACAT TGAGGAAATG
    AAGTTGAAAA ACCCCGGAAG ATACCAGATC ATGAAGGAGA AGGGCAAGAG GTCATCTGAG
    CACATCCAGC GCATCGACCG GGACATAAGC GGGACATTAA GGAAGCATAT GTTCTTCAGG
    GATCGATACG GAACCAAGCA GCGGGAACTA CTCCACATCC TCCTGGCATA TGAGGAGTAT
    AACCCGGAGG TGGGCTACTG CAGGGACCTG AGCCACATCG CCGCCTTGTT CCTCCTCTAT
    CTTCCTGAGG AGGATGCATT CTGGGCACTG GTGCAGCTGC TGGCCAGTGA GAGGCACTCC
    CTGCAGGGAT TTCACAGCCC AAATGGCGGG ACCGTCCAGG GGCTCCAAGA CCAACAGGAG
    CATGTGGTAG CCACGTCACA ATCCAAGACC ATGGGGCATC AGGACAAGAA AGATCTATGT
    GGGCAGTGTT CCCCGTTAGG CTGCCTCATC CGGATATTGA TTGACGGGAT CTCTCTCGGG
    CTCACCCTGC GCCTGTGGGA CGTGTATCTG GTAGAAGGCG AACAGGCGTT GATGCCGATA
    ACAAGAATCG CCTTTAAGGT TCAGCAGAAG CGCCTCACGA AGACGTCCAG GTGTGGCCCG
    TGGGCACGTT TTTGCAACCG GTTCGTTGAT ACCTGGGCCA GGGATGAGGA CACTGTGCTC
    AAGCATCTTA GGGCCTCTAT GAAGAAACTA ACAAGAAAGC AGGGGGACCT GCCACCCCCA
    GCCAAACCCG AGCAAGGGTC GTCGGCATCC AGGCCTGTGC CGGCTTCACG TGGCAGGAAG
    ACCCTCTGCA AGGGGGACAG GCAGGCCCCT CCAGGCCCAC CAGCCCGGTT CCCGCGGCCC
    ATTTGGTCAG CTTCCCCGCC ACGGGCACCT CGTTCTTCCA CACCCTGTCC TGGTGGGGCT
    GTCCGGGAAG ACACCTACCC TGTGGGCACT CAGGGTGTGC CCAGCCCGGC CCTGGCTCAG
    GGAGGACCTC AGGGTTCCTG GAGATTCCTG CAGTGGAACT CCATGCCCCG CCTCCCAACG
    GACCTGGACG TAGAGGGGCC TTGGTTCCGC CATTATGATT TCAGACAGAG CTGCTGGGTC
    CGTGCCATAT CCCAGGAGGA CCAGCTGGCC CCCTGCTGGC AGGCTGAACA CCCTGCGGAG
    CGGGTGAGAT CGGCTTTCGC TGCACCCAGC ACTGATTCCG ACCAGGGCAC CCCCTTCAGA
    GCTAGGGACG AACAGCAGTG TGCTCCCACC TCAGGGCCTT GCCTCTGCGG CCTCCACTTG
    GAAAGTTCTC AGTTCCCTCC AGGCTTCTAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001001417.6
    CDS147..1796
    Translation

    Target ORF information:

    RefSeq Version NM_001001417.6
    Organism Homo sapiens(human)
    Definition Homo sapiens TBC1 domain family member 3B (TBC1D3B), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001001417.6

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGGACGTGG TAGAGGTCGC GGGTAGTTGG TGGGCACAAG AGCGAGAGGA CATCATTATG 
    AAATACGAAA AGGGACACCG AGCTGGGCTG CCAGAGGACA AGGGGCCTAA GCCTTTTCGA
    AGCTACAACA ACAACGTCGA TCATTTGGGG ATTGTACATG AGACGGAGCT GCCTCCTCTG
    ACTGCGCGGG AGGCGAAGCA AATTCGGCGG GAGATCAGCC GAAAGAGCAA GTGGGTGGAT
    ATGCTGGGAG ACTGGGAGAA ATACAAAAGC AGCAGAAAGC TCATAGATCG AGCGTACAAG
    GGAATGCCCA TGAACATCCG GGGCCCGATG TGGTCAGTCC TCCTGAACAT TGAGGAAATG
    AAGTTGAAAA ACCCCGGAAG ATACCAGATC ATGAAGGAGA AGGGCAAGAG GTCATCTGAG
    CACATCCAGC GCATCGACCG GGACATAAGC GGGACATTAA GGAAGCATAT GTTCTTCAGG
    GATCGATACG GAACCAAGCA GCGGGAACTA CTCCACATCC TCCTGGCATA TGAGGAGTAT
    AACCCGGAGG TGGGCTACTG CAGGGACCTG AGCCACATCG CCGCCTTGTT CCTCCTCTAT
    CTTCCTGAGG AGGATGCATT CTGGGCACTG GTGCAGCTGC TGGCCAGTGA GAGGCACTCC
    CTGCAGGGAT TTCACAGCCC AAATGGCGGG ACCGTCCAGG GGCTCCAAGA CCAACAGGAG
    CATGTGGTAG CCACGTCACA ATCCAAGACC ATGGGGCATC AGGACAAGAA AGATCTATGT
    GGGCAGTGTT CCCCGTTAGG CTGCCTCATC CGGATATTGA TTGACGGGAT CTCTCTCGGG
    CTCACCCTGC GCCTGTGGGA CGTGTATCTG GTAGAAGGCG AACAGGCGTT GATGCCGATA
    ACAAGAATCG CCTTTAAGGT TCAGCAGAAG CGCCTCACGA AGACGTCCAG GTGTGGCCCG
    TGGGCACGTT TTTGCAACCG GTTCGTTGAT ACCTGGGCCA GGGATGAGGA CACTGTGCTC
    AAGCATCTTA GGGCCTCTAT GAAGAAACTA ACAAGAAAGC AGGGGGACCT GCCACCCCCA
    GCCAAACCCG AGCAAGGGTC GTCGGCATCC AGGCCTGTGC CGGCTTCACG TGGCAGGAAG
    ACCCTCTGCA AGGGGGACAG GCAGGCCCCT CCAGGCCCAC CAGCCCGGTT CCCGCGGCCC
    ATTTGGTCAG CTTCCCCGCC ACGGGCACCT CGTTCTTCCA CACCCTGTCC TGGTGGGGCT
    GTCCGGGAAG ACACCTACCC TGTGGGCACT CAGGGTGTGC CCAGCCCGGC CCTGGCTCAG
    GGAGGACCTC AGGGTTCCTG GAGATTCCTG CAGTGGAACT CCATGCCCCG CCTCCCAACG
    GACCTGGACG TAGAGGGGCC TTGGTTCCGC CATTATGATT TCAGACAGAG CTGCTGGGTC
    CGTGCCATAT CCCAGGAGGA CCAGCTGGCC CCCTGCTGGC AGGCTGAACA CCCTGCGGAG
    CGGGTGAGAT CGGCTTTCGC TGCACCCAGC ACTGATTCCG ACCAGGGCAC CCCCTTCAGA
    GCTAGGGACG AACAGCAGTG TGCTCCCACC TCAGGGCCTT GCCTCTGCGG CCTCCACTTG
    GAAAGTTCTC AGTTCCCTCC AGGCTTCTAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu50391
    Clone ID Related Accession (Same CDS sequence) XM_005257980.4
    Accession Version XM_005257980.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1833bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product TBC1 domain family member 3B isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005257980.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGGACGTGG TAGAGGTCGC GGGTAGTTGG TGGGCACAAG AGCGAGAGGA CATCATTATG 
    AAATACGAAA AGGGACACCG AGCTGGGCTG CCAGAGGACA AGGGGCCTAA GCCTTTTCGA
    AGCTACAACA ACAACGTCGA TCATTTGGGG ATTGTACAGT CCTGCCCCTC CTGGGAGTCA
    GCCCCACAGG AAGGCCCTTG TCCTCCCTTC CCTGTGCCTT CTCCTGGGCT GAGCCCTGAG
    CTGGAAAGGG ACAGAGCCAG TCCTTTCTGG GGGTCGGCAC CCAGGCTGGG GCCGCTCCAG
    GCCCCGTGCA GTTCCTCAGC TCTGCCTGGG TTGCCTTACA GTGAGACGGA GCTGCCTCCT
    CTGACTGCGC GGGAGGCGAA GCAAATTCGG CGGGAGATCA GCCGAAAGAG CAAGTGGGTG
    GATATGCTGG GAGACTGGGA GAAATACAAA AGCAGCAGAA AGCTCATAGA TCGAGCGTAC
    AAGGGAATGC CCATGAACAT CCGGGGCCCG ATGTGGTCAG TCCTCCTGAA CATTGAGGAA
    ATGAAGTTGA AAAACCCCGG AAGATACCAG ATCATGAAGG AGAAGGGCAA GAGGTCATCT
    GAGCACATCC AGCGCATCGA CCGGGACATA AGCGGGACAT TAAGGAAGCA TATGTTCTTC
    AGGGATCGAT ACGGAACCAA GCAGCGGGAA CTACTCCACA TCCTCCTGGC ATATGAGGAG
    TATAACCCGG AGGTGGGCTA CTGCAGGGAC CTGAGCCACA TCGCCGCCTT GTTCCTCCTC
    TATCTTCCTG AGGAGGATGC ATTCTGGGCA CTGGTGCAGC TGCTGGCCAG TGAGAGGCAC
    TCCCTGCAGG GATTTCACAG CCCAAATGGC GGGACCGTCC AGGGGCTCCA AGACCAACAG
    GAGCATGTGG TAGCCACGTC ACAATCCAAG ACCATGGGGC ATCAGGACAA GAAAGATCTA
    TGTGGGCAGT GTTCCCCGTT AGGCTGCCTC ATCCGGATAT TGATTGACGG GATCTCTCTC
    GGGCTCACCC TGCGCCTGTG GGACGTGTAT CTGGTAGAAG GCGAACAGGC GTTGATGCCG
    ATAACAAGAA TCGCCTTTAA GGTTCAGCAG AAGCGCCTCA CGAAGACGTC CAGGTGTGGC
    CCGTGGGCAC GTTTTTGCAA CCGGTTCGTT GATACCTGGG CCAGGGATGA GGACACTGTG
    CTCAAGCATC TTAGGGCCTC TATGAAGAAA CTAACAAGAA AGCAGGGGGA CCTGCCACCC
    CCAGCCAAAC CCGAGCAAGG GTCGTCGGCA TCCAGGCCTG TGCCGGCTTC ACGTGGCAGG
    AAGACCCTCT GCAAGGGGGA CAGGCAGGCC CCTCCAGGCC CACCAGCCCG GTTCCCGCGG
    CCCATTTGGT CAGCTTCCCC GCCACGGGCA CCTCGTTCTT CCACACCCTG TCCTGGTGGG
    GCTGTCCGGG AAGACACCTA CCCTGTGGGC ACTCAGGGTG TGCCCAGCCC GGCCCTGGCT
    CAGGGAGGAC CTCAGGGTTC CTGGAGATTC CTGCAGTGGA ACTCCATGCC CCGCCTCCCA
    ACGGACCTGG ACGTAGAGGG GCCTTGGTTC CGCCATTATG ATTTCAGACA GAGCTGCTGG
    GTCCGTGCCA TATCCCAGGA GGACCAGCTG GCCCCCTGCT GGCAGGCTGA ACACCCTGCG
    GAGCGGGTGA GATCGGCTTT CGCTGCACCC AGCACTGATT CCGACCAGGG CACCCCCTTC
    AGAGCTAGGG ACGAACAGCA GTGTGCTCCC ACCTCAGGGC CTTGCCTCTG CGGCCTCCAC
    TTGGAAAGTT CTCAGTTCCC TCCAGGCTTC TAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_005258037.2
    CDS94..1926
    Translation

    Target ORF information:

    RefSeq Version XM_005257980.4
    Organism Homo sapiens(human)
    Definition Homo sapiens TBC1 domain family member 3B (TBC1D3B), transcript variant X1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_005257980.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGGACGTGG TAGAGGTCGC GGGTAGTTGG TGGGCACAAG AGCGAGAGGA CATCATTATG 
    AAATACGAAA AGGGACACCG AGCTGGGCTG CCAGAGGACA AGGGGCCTAA GCCTTTTCGA
    AGCTACAACA ACAACGTCGA TCATTTGGGG ATTGTACAGT CCTGCCCCTC CTGGGAGTCA
    GCCCCACAGG AAGGCCCTTG TCCTCCCTTC CCTGTGCCTT CTCCTGGGCT GAGCCCTGAG
    CTGGAAAGGG ACAGAGCCAG TCCTTTCTGG GGGTCGGCAC CCAGGCTGGG GCCGCTCCAG
    GCCCCGTGCA GTTCCTCAGC TCTGCCTGGG TTGCCTTACA GTGAGACGGA GCTGCCTCCT
    CTGACTGCGC GGGAGGCGAA GCAAATTCGG CGGGAGATCA GCCGAAAGAG CAAGTGGGTG
    GATATGCTGG GAGACTGGGA GAAATACAAA AGCAGCAGAA AGCTCATAGA TCGAGCGTAC
    AAGGGAATGC CCATGAACAT CCGGGGCCCG ATGTGGTCAG TCCTCCTGAA CATTGAGGAA
    ATGAAGTTGA AAAACCCCGG AAGATACCAG ATCATGAAGG AGAAGGGCAA GAGGTCATCT
    GAGCACATCC AGCGCATCGA CCGGGACATA AGCGGGACAT TAAGGAAGCA TATGTTCTTC
    AGGGATCGAT ACGGAACCAA GCAGCGGGAA CTACTCCACA TCCTCCTGGC ATATGAGGAG
    TATAACCCGG AGGTGGGCTA CTGCAGGGAC CTGAGCCACA TCGCCGCCTT GTTCCTCCTC
    TATCTTCCTG AGGAGGATGC ATTCTGGGCA CTGGTGCAGC TGCTGGCCAG TGAGAGGCAC
    TCCCTGCAGG GATTTCACAG CCCAAATGGC GGGACCGTCC AGGGGCTCCA AGACCAACAG
    GAGCATGTGG TAGCCACGTC ACAATCCAAG ACCATGGGGC ATCAGGACAA GAAAGATCTA
    TGTGGGCAGT GTTCCCCGTT AGGCTGCCTC ATCCGGATAT TGATTGACGG GATCTCTCTC
    GGGCTCACCC TGCGCCTGTG GGACGTGTAT CTGGTAGAAG GCGAACAGGC GTTGATGCCG
    ATAACAAGAA TCGCCTTTAA GGTTCAGCAG AAGCGCCTCA CGAAGACGTC CAGGTGTGGC
    CCGTGGGCAC GTTTTTGCAA CCGGTTCGTT GATACCTGGG CCAGGGATGA GGACACTGTG
    CTCAAGCATC TTAGGGCCTC TATGAAGAAA CTAACAAGAA AGCAGGGGGA CCTGCCACCC
    CCAGCCAAAC CCGAGCAAGG GTCGTCGGCA TCCAGGCCTG TGCCGGCTTC ACGTGGCAGG
    AAGACCCTCT GCAAGGGGGA CAGGCAGGCC CCTCCAGGCC CACCAGCCCG GTTCCCGCGG
    CCCATTTGGT CAGCTTCCCC GCCACGGGCA CCTCGTTCTT CCACACCCTG TCCTGGTGGG
    GCTGTCCGGG AAGACACCTA CCCTGTGGGC ACTCAGGGTG TGCCCAGCCC GGCCCTGGCT
    CAGGGAGGAC CTCAGGGTTC CTGGAGATTC CTGCAGTGGA ACTCCATGCC CCGCCTCCCA
    ACGGACCTGG ACGTAGAGGG GCCTTGGTTC CGCCATTATG ATTTCAGACA GAGCTGCTGG
    GTCCGTGCCA TATCCCAGGA GGACCAGCTG GCCCCCTGCT GGCAGGCTGA ACACCCTGCG
    GAGCGGGTGA GATCGGCTTT CGCTGCACCC AGCACTGATT CCGACCAGGG CACCCCCTTC
    AGAGCTAGGG ACGAACAGCA GTGTGCTCCC ACCTCAGGGC CTTGCCTCTG CGGCCTCCAC
    TTGGAAAGTT CTCAGTTCCC TCCAGGCTTC TAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.
    Genomics88(6)731-736(2006 Dec)
    Hodzic D,Kong C,Wainszelbaum MJ,Charron AJ,Su X,Stahl PD


    DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
    Nature440(7087)1045-9(2006 Apr)
    Zody MC,Garber M,Adams DJ,Sharpe T,Harrow J,Lupski JR,Nicholson C,Searle SM,Wilming L,Young SK,Abouelleil A,Allen NR,Bi W,Bloom T,Borowsky ML,Bugalter BE,Butler J,Chang JL,Chen CK,Cook A,Corum B,Cuomo CA,de Jong PJ,DeCaprio D,Dewar K,FitzGerald M,Gilbert J,Gibson R,Gnerre S,Goldstein S,Grafham DV,Grocock R,Hafez N,Hagopian DS,Hart E,Norman CH,Humphray S,Jaffe DB,Jones M,Kamal M,Khodiyar VK,LaButti K,Laird G,Lehoczky J,Liu X,Lokyitsang T,Loveland J,Lui A,Macdonald P,Major JE,Matthews L,Mauceli E,McCarroll SA,Mihalev AH,Mudge J,Nguyen C,Nicol R,O'Leary SB,Osoegawa K,Schwartz DC,Shaw-Smith C,Stankiewicz P,Steward C,Swarbreck D,Venkataraman V,Whittaker CA,Yang X,Zimmer AR,Bradley A,Hubbard T,Birren BW,Rogers J,Lander ES,Nusbaum C