MAGEB2 cDNA ORF clone, Homo sapiens(human)

Aberrant demethylation and expression of MAGEB2 in a subset of malignant peripheral nerve sheath tumors from neurofibromatosis type 1.
Nobeyama Y, Nakagawa H
Journal of dermatological science81(2)118-23(2016 Feb)

Human MageB2 Protein Expression Enhances E2F Transcriptional Activity, Cell Proliferation, and Resistance to Ribotoxic Stress.
Peche LY, Ladelfa MF, Toledo MF, Mano M, Laiseca JE, Schneider C, Monte M
The Journal of biological chemistry290(49)29652-62(2015 Dec)

MAGEB2 is activated by promoter demethylation in head and neck squamous cell carcinoma.
Pattani KM, Soudry E, Glazer CA, Ochs MF, Wang H, Schussel J, Sun W, Hennessey P, Mydlarz W, Loyo M, Demokan S, Smith IM, Califano JA
PloS one7(9)e45534(2012)

Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes.
Milutinovic S, D'Alessio AC, Detich N, Szyf M
Carcinogenesis28(3)560-71(2007 Mar)

The DNA sequence of the human X chromosome.
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Nature434(7031)325-37(2005 Mar)

MAGEB2 can be aberrantly demethylated and expressed in malignant peripheral nerve sheath tumors. Conversely, the gene may not be demethylated in any types of neurofibroma, suggesting that the demethylation does not occur before malignant transformation.
Title: Aberrant demethylation and expression of MAGEB2 in a subset of malignant peripheral nerve sheath tumors from neurofibromatosis type 1.

MageB2 counteracts E2F inhibition by ribosomal proteins independently of Mdm2 expression
Title: Human MageB2 Protein Expression Enhances E2F Transcriptional Activity, Cell Proliferation, and Resistance to Ribotoxic Stress.

we identified MAGEB2 as activated by promoter demethylation in HNSCCand demonstrates growth promoting effects in a minimally transformed oral keratinocyte cell line.
Title: MAGEB2 is activated by promoter demethylation in head and neck squamous cell carcinoma.

Valproic acid causes a change in acetylation of this gene.
Title: Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes.

Results show that hypertonic culture medium differentially induces the expression of melanoma antigens B1 and B2 (MAGE-B1, -B2) in different human tumor cell lines.
Title: Hypertonicity induction of melanoma antigen, a tumor-associated antigen.