ARF3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ARF3
Entrez Gene ID	377
Full Name	ADP ribosylation factor 3
General protein information	Preferred Names ADP ribosylation factor 3 Names ADP-ribosylation factor 3 small GTP binding protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q13.12
Summary	ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns. [provided by RefSeq, Jul 2008].
Disorder MIM:	103190

mRNA and Protein(s)

mRNA	Protein	Name
NM_001659.2	NP_001650.1	ADP-ribosylation factor 3
XM_006719391.4	XP_006719454.1	ADP-ribosylation factor 3 isoform X2
XM_024448972.1	XP_024304740.1	ADP-ribosylation factor 3 isoform X1
XM_005268856.1	XP_005268913.1	ADP-ribosylation factor 3 isoform X1
XM_006719391.3	XP_006719454.1	ADP-ribosylation factor 3 isoform X2
NM_001659.3	NP_001650.1	ADP-ribosylation factor 3

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ARF3	NP_001015571.1
Rattus norvegicus (Norway rat)	Arf3	NP_543180.1
Danio rerio (zebrafish)	arf3a	NP_001003441.1
Homo sapiens (human)	ARF3	NP_001650.1
Arabidopsis thaliana (thale cress)	ARF1A1C	NP_182239.1
Oryza sativa (rice)	Os07g0223400	NP_001059207.1
	LOC708716	XP_001104802.2
Canis lupus familiaris (dog)	ARF3	XP_005636947.1
Arabidopsis thaliana (thale cress)	ARFA1E	NP_001190161.1
Arabidopsis thaliana (thale cress)	ARFA1F	NP_172533.2
Xenopus tropicalis (tropical clawed frog)	arf3	NP_001120153.1
Pan troglodytes (chimpanzee)	ARF3	XP_003313778.1
Mus musculus (house mouse)	Arf3	NP_031504.1
Arabidopsis thaliana (thale cress)	ARFA1D	NP_177206.1
Arabidopsis thaliana (thale cress)	ARF1	NP_564195.1

Gene Ontology
Bibliography

Related articles in PubMed

Overexpression of ARF1 is associated with cell proliferation and migration through PI3K signal pathway in ovarian cancer.
Gu G, Chen Y, Duan C, Zhou L, Chen C, Chen J, Cheng J, Shi N, Jin Y, Xi Q, Zhong J
Oncology reports37(3)1511-1520(2017 Mar)

Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis.
Hanai A, Ohgi M, Yagi C, Ueda T, Shin HW, Nakayama K
Journal of biochemistry159(2)201-8(2016 Feb)

ADP-Ribosylation Factor 3 Mediates Cytidine-Phosphate-Guanosine Oligodeoxynucleotide-Induced Responses by Regulating Toll-Like Receptor 9 Trafficking.
Wu JY, Kuo CC
Journal of innate immunity7(6)623-36(2015)

WLS retrograde transport to the endoplasmic reticulum during Wnt secretion.
Yu J, Chia J, Canning CA, Jones CM, Bard FA, Virshup DM
Developmental cell29(3)277-91(2014 May)

ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus.
Nakai W, Kondo Y, Saitoh A, Naito T, Nakayama K, Shin HW
Molecular biology of the cell24(16)2570-81(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Upregulation of ARF3 is associated with ovarian cancer.
Title: Overexpression of ARF1 is associated with cell proliferation and migration through PI3K signal pathway in ovarian cancer.

observations indicate that Arf1 and Arf3 as well as Arf6 play important roles in cytokinesis.
Title: Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis.

activated ARF3 is associated with Unc93B1 and TLR9, suggesting that ARF3 conducts TLR9 trafficking by forming the TLR9-Unc93B1-ARF3 complex.
Title: ADP-Ribosylation Factor 3 Mediates Cytidine-Phosphate-Guanosine Oligodeoxynucleotide-Induced Responses by Regulating Toll-Like Receptor 9 Trafficking.

ARF1+ARF3 are required for integrity of recycling endosomes but are involved in distinct transport pathways: they are required for the transferrin recycling pathway from endosomes to the plasma membrane.
Title: ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus.

ARF1 and ARF3 are redundantly required for the integrity of recycling endosomes
Title: ARF1 and ARF3 are required for the integrity of recycling endosomes and the recycling pathway.

The following ARF3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ARF3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15164	NM_001659.2 Latest version!	Homo sapiens ADP ribosylation factor 3 (ARF3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu46540	NM_001659.3 Latest version!	Homo sapiens ADP ribosylation factor 3 (ARF3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu46540	XM_024448972.1 Latest version!	Homo sapiens ADP ribosylation factor 3 (ARF3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu46540	XM_005268856.1 Latest version!	Homo sapiens ADP ribosylation factor 3 (ARF3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu46541	XM_006719391.4 Latest version!	Homo sapiens ADP ribosylation factor 3 (ARF3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu46541	XM_006719391.3	Homo sapiens ADP ribosylation factor 3 (ARF3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ARF3 ( NM_001659.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001650.1 Homo sapiens ADP ribosylation factor 3 (ARF3), mRNA.

Price & Availability↑

CloneID	OHu15164
Clone ID Related Accession (Same CDS sequence)	NM_001659.2
Accession Version	NM_001659.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM966960.1, BC028402.2 and BC017565.2. On Apr 29, 2008 this sequence version replaced NM_001659.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M74491.1, BC028402.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGGCAATA TCTTTGGAAA CCTTCTCAAG AGCCTGATTG GGAAGAAGGA GATGCGCATC 
CTGATGGTGG GCCTGGATGC CGCAGGAAAG ACCACCATCC TATACAAGCT GAAACTGGGG 
GAGATCGTCA CCACCATCCC TACCATTGGG TTCAATGTGG AGACAGTGGA GTATAAGAAC 
ATCAGCTTTA CAGTGTGGGA TGTGGGTGGC CAGGACAAGA TTCGACCCCT CTGGAGACAC 
TACTTCCAGA ACACCCAAGG GTTGATATTT GTGGTCGACA GCAATGATCG GGAGCGAGTA 
AATGAGGCCC GGGAAGAGCT GATGAGAATG CTGGCGGAGG ACGAGCTCCG GGATGCTGTA 
CTCCTTGTCT TTGCAAACAA ACAGGATCTG CCTAATGCTA TGAACGCTGC TGAGATCACA 
GACAAGCTGG GCCTGCATTC CCTTCGTCAC CGTAACTGGT ACATTCAGGC CACCTGTGCC 
ACCAGCGGGG ACGGGCTGTA CGAAGGCCTG GACTGGCTGG CCAATCAGCT CAAAAACAAG 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001650.1
CDS	254..799
Translation	MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK

Target ORF information:

RefSeq Version	NM_001659.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP ribosylation factor 3 (ARF3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001659.2

ORF Insert Sequence:

ATGGGCAATA TCTTTGGAAA CCTTCTCAAG AGCCTGATTG GGAAGAAGGA GATGCGCATC 
CTGATGGTGG GCCTGGATGC CGCAGGAAAG ACCACCATCC TATACAAGCT GAAACTGGGG 
GAGATCGTCA CCACCATCCC TACCATTGGG TTCAATGTGG AGACAGTGGA GTATAAGAAC 
ATCAGCTTTA CAGTGTGGGA TGTGGGTGGC CAGGACAAGA TTCGACCCCT CTGGAGACAC 
TACTTCCAGA ACACCCAAGG GTTGATATTT GTGGTCGACA GCAATGATCG GGAGCGAGTA 
AATGAGGCCC GGGAAGAGCT GATGAGAATG CTGGCGGAGG ACGAGCTCCG GGATGCTGTA 
CTCCTTGTCT TTGCAAACAA ACAGGATCTG CCTAATGCTA TGAACGCTGC TGAGATCACA 
GACAAGCTGG GCCTGCATTC CCTTCGTCAC CGTAACTGGT ACATTCAGGC CACCTGTGCC 
ACCAGCGGGG ACGGGCTGTA CGAAGGCCTG GACTGGCTGG CCAATCAGCT CAAAAACAAG 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARF3 ( NM_001659.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001650.1 Homo sapiens ADP ribosylation factor 3 (ARF3), mRNA.

Price & Availability↑

CloneID	OHu46540
Clone ID Related Accession (Same CDS sequence)	XM_024448972.1 , XM_005268856.1 , NM_001659.3
Accession Version	NM_001659.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC073610.17. On Nov 23, 2018 this sequence version replaced NM_001659.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M74491.1, SRR3476690.1025705.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000256682.9/ ENSP00000256682.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGCAATA TCTTTGGAAA CCTTCTCAAG AGCCTGATTG GGAAGAAGGA GATGCGCATC 
CTGATGGTGG GCCTGGATGC CGCAGGAAAG ACCACCATCC TATACAAGCT GAAACTCGGG 
GAGATCGTCA CCACCATCCC TACCATTGGG TTCAATGTGG AGACAGTGGA GTATAAGAAC 
ATCAGCTTTA CAGTGTGGGA TGTGGGTGGC CAGGACAAGA TTCGACCCCT CTGGAGACAC 
TACTTCCAGA ACACCCAAGG GTTGATATTT GTGGTCGACA GCAATGATCG GGAGCGAGTA 
AATGAGGCCC GGGAAGAGCT GATGAGAATG CTGGCGGAGG ACGAGCTCCG GGATGCTGTA 
CTCCTTGTCT TTGCAAACAA ACAGGATCTG CCTAATGCTA TGAACGCTGC TGAGATCACA 
GACAAGCTGG GCCTGCATTC CCTTCGTCAC CGTAACTGGT ACATTCAGGC CACCTGTGCC 
ACCAGCGGGG ACGGGCTGTA CGAAGGCCTG GACTGGCTGG CCAATCAGCT CAAAAACAAG 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001650.1
CDS	272..817
Translation	MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK

Target ORF information:

RefSeq Version	NM_001659.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP ribosylation factor 3 (ARF3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001659.3

ORF Insert Sequence:

ATGGGCAATA TCTTTGGAAA CCTTCTCAAG AGCCTGATTG GGAAGAAGGA GATGCGCATC 
CTGATGGTGG GCCTGGATGC CGCAGGAAAG ACCACCATCC TATACAAGCT GAAACTCGGG 
GAGATCGTCA CCACCATCCC TACCATTGGG TTCAATGTGG AGACAGTGGA GTATAAGAAC 
ATCAGCTTTA CAGTGTGGGA TGTGGGTGGC CAGGACAAGA TTCGACCCCT CTGGAGACAC 
TACTTCCAGA ACACCCAAGG GTTGATATTT GTGGTCGACA GCAATGATCG GGAGCGAGTA 
AATGAGGCCC GGGAAGAGCT GATGAGAATG CTGGCGGAGG ACGAGCTCCG GGATGCTGTA 
CTCCTTGTCT TTGCAAACAA ACAGGATCTG CCTAATGCTA TGAACGCTGC TGAGATCACA 
GACAAGCTGG GCCTGCATTC CCTTCGTCAC CGTAACTGGT ACATTCAGGC CACCTGTGCC 
ACCAGCGGGG ACGGGCTGTA CGAAGGCCTG GACTGGCTGG CCAATCAGCT CAAAAACAAG 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARF3 ( XM_024448972.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024304740.1 Homo sapiens ADP ribosylation factor 3 (ARF3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu46540
Clone ID Related Accession (Same CDS sequence)	XM_024448972.1 , XM_005268856.1 , NM_001659.3
Accession Version	XM_024448972.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAATA TCTTTGGAAA CCTTCTCAAG AGCCTGATTG GGAAGAAGGA GATGCGCATC 
CTGATGGTGG GCCTGGATGC CGCAGGAAAG ACCACCATCC TATACAAGCT GAAACTCGGG 
GAGATCGTCA CCACCATCCC TACCATTGGG TTCAATGTGG AGACAGTGGA GTATAAGAAC 
ATCAGCTTTA CAGTGTGGGA TGTGGGTGGC CAGGACAAGA TTCGACCCCT CTGGAGACAC 
TACTTCCAGA ACACCCAAGG GTTGATATTT GTGGTCGACA GCAATGATCG GGAGCGAGTA 
AATGAGGCCC GGGAAGAGCT GATGAGAATG CTGGCGGAGG ACGAGCTCCG GGATGCTGTA 
CTCCTTGTCT TTGCAAACAA ACAGGATCTG CCTAATGCTA TGAACGCTGC TGAGATCACA 
GACAAGCTGG GCCTGCATTC CCTTCGTCAC CGTAACTGGT ACATTCAGGC CACCTGTGCC 
ACCAGCGGGG ACGGGCTGTA CGAAGGCCTG GACTGGCTGG CCAATCAGCT CAAAAACAAG 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024304740.1
CDS	437..982
Translation	MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK

Target ORF information:

RefSeq Version	XM_024448972.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP ribosylation factor 3 (ARF3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024448972.1

ORF Insert Sequence:

ATGGGCAATA TCTTTGGAAA CCTTCTCAAG AGCCTGATTG GGAAGAAGGA GATGCGCATC 
CTGATGGTGG GCCTGGATGC CGCAGGAAAG ACCACCATCC TATACAAGCT GAAACTCGGG 
GAGATCGTCA CCACCATCCC TACCATTGGG TTCAATGTGG AGACAGTGGA GTATAAGAAC 
ATCAGCTTTA CAGTGTGGGA TGTGGGTGGC CAGGACAAGA TTCGACCCCT CTGGAGACAC 
TACTTCCAGA ACACCCAAGG GTTGATATTT GTGGTCGACA GCAATGATCG GGAGCGAGTA 
AATGAGGCCC GGGAAGAGCT GATGAGAATG CTGGCGGAGG ACGAGCTCCG GGATGCTGTA 
CTCCTTGTCT TTGCAAACAA ACAGGATCTG CCTAATGCTA TGAACGCTGC TGAGATCACA 
GACAAGCTGG GCCTGCATTC CCTTCGTCAC CGTAACTGGT ACATTCAGGC CACCTGTGCC 
ACCAGCGGGG ACGGGCTGTA CGAAGGCCTG GACTGGCTGG CCAATCAGCT CAAAAACAAG 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARF3 ( XM_005268856.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268913.1 Homo sapiens ADP ribosylation factor 3 (ARF3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu46540
Clone ID Related Accession (Same CDS sequence)	XM_024448972.1 , XM_005268856.1 , NM_001659.3
Accession Version	XM_005268856.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAATA TCTTTGGAAA CCTTCTCAAG AGCCTGATTG GGAAGAAGGA GATGCGCATC 
CTGATGGTGG GCCTGGATGC CGCAGGAAAG ACCACCATCC TATACAAGCT GAAACTCGGG 
GAGATCGTCA CCACCATCCC TACCATTGGG TTCAATGTGG AGACAGTGGA GTATAAGAAC 
ATCAGCTTTA CAGTGTGGGA TGTGGGTGGC CAGGACAAGA TTCGACCCCT CTGGAGACAC 
TACTTCCAGA ACACCCAAGG GTTGATATTT GTGGTCGACA GCAATGATCG GGAGCGAGTA 
AATGAGGCCC GGGAAGAGCT GATGAGAATG CTGGCGGAGG ACGAGCTCCG GGATGCTGTA 
CTCCTTGTCT TTGCAAACAA ACAGGATCTG CCTAATGCTA TGAACGCTGC TGAGATCACA 
GACAAGCTGG GCCTGCATTC CCTTCGTCAC CGTAACTGGT ACATTCAGGC CACCTGTGCC 
ACCAGCGGGG ACGGGCTGTA CGAAGGCCTG GACTGGCTGG CCAATCAGCT CAAAAACAAG 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268913.1
CDS	568..1113
Translation	MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK

Target ORF information:

RefSeq Version	XM_005268856.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP ribosylation factor 3 (ARF3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005268856.1

ORF Insert Sequence:

ATGGGCAATA TCTTTGGAAA CCTTCTCAAG AGCCTGATTG GGAAGAAGGA GATGCGCATC 
CTGATGGTGG GCCTGGATGC CGCAGGAAAG ACCACCATCC TATACAAGCT GAAACTCGGG 
GAGATCGTCA CCACCATCCC TACCATTGGG TTCAATGTGG AGACAGTGGA GTATAAGAAC 
ATCAGCTTTA CAGTGTGGGA TGTGGGTGGC CAGGACAAGA TTCGACCCCT CTGGAGACAC 
TACTTCCAGA ACACCCAAGG GTTGATATTT GTGGTCGACA GCAATGATCG GGAGCGAGTA 
AATGAGGCCC GGGAAGAGCT GATGAGAATG CTGGCGGAGG ACGAGCTCCG GGATGCTGTA 
CTCCTTGTCT TTGCAAACAA ACAGGATCTG CCTAATGCTA TGAACGCTGC TGAGATCACA 
GACAAGCTGG GCCTGCATTC CCTTCGTCAC CGTAACTGGT ACATTCAGGC CACCTGTGCC 
ACCAGCGGGG ACGGGCTGTA CGAAGGCCTG GACTGGCTGG CCAATCAGCT CAAAAACAAG 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARF3 ( XM_006719391.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_006719454.1 Homo sapiens ADP ribosylation factor 3 (ARF3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu46541
Clone ID Related Accession (Same CDS sequence)	XM_006719391.4 , XM_006719391.3
Accession Version	XM_006719391.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 414bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006719391.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAATA TCTTTGGAAA CCTTCTCAAG AGCCTGATTG GGAAGAAGGA GATGCGCATC 
CTGATGGTGG GCCTGGATGC CGCAGGAAAG ACCACCATCC TATACAAGCT GAAACTCGGG 
GAGATCGTCA CCACCATCCC TACCATTGGG TTCAATGTGG AGACAGTGGA GTATAAGAAC 
ATCAGCTTTA CAGTGTGGGA TGTGGGTGGC CAGGACAAGA TTCGACCCCT CTGGAGACAC 
TACTTCCAGA ACACCCAAGG GTTGATATTT GTGGTCGACA GCAATGATCG GGAGCGAGTA 
AATGAGGCCC GGGAAGAGCT GATGAGAATG CTGGCGGAGG ACGAGCTCCG GGATGCTGTA 
CTCCTTGTCT TTGCAAACAA ACAGGTTCCT GAACAGAGCC TCAGACCTGG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006719454.1
CDS	311..724
Translation	MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQVPEQSLRPG

Target ORF information:

RefSeq Version	XM_006719391.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP ribosylation factor 3 (ARF3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006719391.4

ORF Insert Sequence:

ATGGGCAATA TCTTTGGAAA CCTTCTCAAG AGCCTGATTG GGAAGAAGGA GATGCGCATC 
CTGATGGTGG GCCTGGATGC CGCAGGAAAG ACCACCATCC TATACAAGCT GAAACTCGGG 
GAGATCGTCA CCACCATCCC TACCATTGGG TTCAATGTGG AGACAGTGGA GTATAAGAAC 
ATCAGCTTTA CAGTGTGGGA TGTGGGTGGC CAGGACAAGA TTCGACCCCT CTGGAGACAC 
TACTTCCAGA ACACCCAAGG GTTGATATTT GTGGTCGACA GCAATGATCG GGAGCGAGTA 
AATGAGGCCC GGGAAGAGCT GATGAGAATG CTGGCGGAGG ACGAGCTCCG GGATGCTGTA 
CTCCTTGTCT TTGCAAACAA ACAGGTTCCT GAACAGAGCC TCAGACCTGG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARF3 ( XM_006719391.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006719454.1 Homo sapiens ADP ribosylation factor 3 (ARF3), transcript variant X2, mRNA.

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CloneID	OHu46541
Clone ID Related Accession (Same CDS sequence)	XM_006719391.4 , XM_006719391.3
Accession Version	XM_006719391.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 414bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006719391.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAATA TCTTTGGAAA CCTTCTCAAG AGCCTGATTG GGAAGAAGGA GATGCGCATC 
CTGATGGTGG GCCTGGATGC CGCAGGAAAG ACCACCATCC TATACAAGCT GAAACTCGGG 
GAGATCGTCA CCACCATCCC TACCATTGGG TTCAATGTGG AGACAGTGGA GTATAAGAAC 
ATCAGCTTTA CAGTGTGGGA TGTGGGTGGC CAGGACAAGA TTCGACCCCT CTGGAGACAC 
TACTTCCAGA ACACCCAAGG GTTGATATTT GTGGTCGACA GCAATGATCG GGAGCGAGTA 
AATGAGGCCC GGGAAGAGCT GATGAGAATG CTGGCGGAGG ACGAGCTCCG GGATGCTGTA 
CTCCTTGTCT TTGCAAACAA ACAGGTTCCT GAACAGAGCC TCAGACCTGG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006719454.1
CDS	311..724
Translation	MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQVPEQSLRPG

Target ORF information:

RefSeq Version	XM_006719391.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP ribosylation factor 3 (ARF3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006719391.3

ORF Insert Sequence:

ATGGGCAATA TCTTTGGAAA CCTTCTCAAG AGCCTGATTG GGAAGAAGGA GATGCGCATC 
CTGATGGTGG GCCTGGATGC CGCAGGAAAG ACCACCATCC TATACAAGCT GAAACTCGGG 
GAGATCGTCA CCACCATCCC TACCATTGGG TTCAATGTGG AGACAGTGGA GTATAAGAAC 
ATCAGCTTTA CAGTGTGGGA TGTGGGTGGC CAGGACAAGA TTCGACCCCT CTGGAGACAC 
TACTTCCAGA ACACCCAAGG GTTGATATTT GTGGTCGACA GCAATGATCG GGAGCGAGTA 
AATGAGGCCC GGGAAGAGCT GATGAGAATG CTGGCGGAGG ACGAGCTCCG GGATGCTGTA 
CTCCTTGTCT TTGCAAACAA ACAGGTTCCT GAACAGAGCC TCAGACCTGG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Overexpression of ARF1 is associated with cell proliferation and migration through PI3K signal pathway in ovarian cancer.
Oncology reports37(3)1511-1520(2017 Mar)
Gu G,Chen Y,Duan C,Zhou L,Chen C,Chen J,Cheng J,Shi N,Jin Y,Xi Q,Zhong J

Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis.
Journal of biochemistry159(2)201-8(2016 Feb)
Hanai A,Ohgi M,Yagi C,Ueda T,Shin HW,Nakayama K

ADP-Ribosylation Factor 3 Mediates Cytidine-Phosphate-Guanosine Oligodeoxynucleotide-Induced Responses by Regulating Toll-Like Receptor 9 Trafficking.
Journal of innate immunity7(6)623-36(2015)
Wu JY,Kuo CC

WLS retrograde transport to the endoplasmic reticulum during Wnt secretion.
Developmental cell29(3)277-91(2014 May)
Yu J,Chia J,Canning CA,Jones CM,Bard FA,Virshup DM

ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus.
Molecular biology of the cell24(16)2570-81(2013 Aug)
Nakai W,Kondo Y,Saitoh A,Naito T,Nakayama K,Shin HW

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ARF3 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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