APP gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_001204302.1	NP_001191231.1	amyloid-beta precursor protein isoform i precursor
NM_001204303.1	NP_001191232.1	amyloid-beta precursor protein isoform j precursor
NM_001204303.2	NP_001191232.1	amyloid-beta precursor protein isoform j precursor
NM_201414.3	NP_958817.1	amyloid-beta precursor protein isoform c precursor
NM_001136016.3	NP_001129488.1	amyloid-beta precursor protein isoform d
NM_001136129.3	NP_001129601.1	amyloid-beta precursor protein isoform e precursor
NM_201413.2	NP_958816.1	amyloid-beta precursor protein isoform b precursor
NM_001136129.2	NP_001129601.1	amyloid-beta precursor protein isoform e precursor
NM_201414.2	NP_958817.1	amyloid-beta precursor protein isoform c precursor
XM_024452075.1	XP_024307843.1	amyloid-beta precursor protein isoform X1
NM_001136131.2	NP_001129603.1	amyloid-beta precursor protein isoform g
NM_001204301.1	NP_001191230.1	amyloid-beta precursor protein isoform h precursor
NM_201413.3	NP_958816.1	amyloid-beta precursor protein isoform b precursor
NM_001136130.3	NP_001129602.1	amyloid-beta precursor protein isoform f precursor
NM_001204301.2	NP_001191230.1	amyloid-beta precursor protein isoform h precursor
NM_001136130.2	NP_001129602.1	amyloid-beta precursor protein isoform f precursor
NM_000484.3	NP_000475.1	amyloid-beta A4 protein isoform a precursor
NM_000484.4	NP_000475.1	amyloid-beta precursor protein isoform a precursor
NM_001204302.2	NP_001191231.1	amyloid-beta precursor protein isoform i precursor

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26689	NM_201414.3 Latest version!	Homo sapiens amyloid beta precursor protein (APP), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$349.50-$489.30 $699.00
OHu26762	NM_201413.3 Latest version!	Homo sapiens amyloid beta precursor protein (APP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu27126	NM_001136129.3 Latest version!	Homo sapiens amyloid beta precursor protein (APP), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu27184	NM_001136131.2 Latest version!	Homo sapiens amyloid beta precursor protein (APP), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$314.50-$440.30 $629.00
OHu27259	NM_000484.4 Latest version!	Homo sapiens amyloid beta precursor protein (APP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu27130	NM_001136016.3 Latest version!	Homo sapiens amyloid beta precursor protein (APP), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$629.30 $899.00
OHu27201	NM_001204302.2 Latest version!	Homo sapiens amyloid beta precursor protein (APP), transcript variant 9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu27229	NM_001204301.2 Latest version!	Homo sapiens amyloid beta precursor protein (APP), transcript variant 8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu27287	NM_001204303.2 Latest version!	Homo sapiens amyloid beta precursor protein (APP), transcript variant 10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu27406	NM_001136130.3 Latest version!	Homo sapiens amyloid beta precursor protein (APP), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$503.30 $719.00
OHu105175	XM_024452075.1 Latest version!	Homo sapiens amyloid beta precursor protein (APP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu27287	NM_001204303.1	Homo sapiens amyloid beta precursor protein (APP), transcript variant 10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu27126	NM_001136129.2	Homo sapiens amyloid beta precursor protein (APP), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu26689	NM_201414.2	Homo sapiens amyloid beta precursor protein (APP), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$349.50-$489.30 $699.00
OHu26762	NM_201413.2	Homo sapiens amyloid beta precursor protein (APP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu27229	NM_001204301.1	Homo sapiens amyloid beta precursor protein (APP), transcript variant 8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu27406	NM_001136130.2	Homo sapiens amyloid beta precursor protein (APP), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$503.30 $719.00
OHu27259	NM_000484.3	Homo sapiens amyloid beta precursor protein (APP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu27201	NM_001204302.1	Homo sapiens amyloid beta precursor protein (APP), transcript variant 9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
Hide Old Accession Versions >>

APP ( NM_201414.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_958817.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu26689
Clone ID Related Accession (Same CDS sequence)	NM_201414.3 , NM_201414.2
Accession Version	NM_201414.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2088bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, Y00264.1 and BM876312.1. On May 31, 2019 this sequence version replaced NM_201414.2. Transcript Variant: This variant (3) lacks an alternate in-frame segment compared to variant 1. The resulting isoform (c, also known as PreA4 695) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.113249.1, SRR1803614.104521.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGTTCCT ACAACAGCAG CCAGTACCCC TGATGCCGTT 
GACAAGTATC TCGAGACACC TGGGGATGAG AATGAACATG CCCATTTCCA GAAAGCCAAA 
GAGAGGCTTG AGGCCAAGCA CCGAGAGAGA ATGTCCCAGG TCATGAGAGA ATGGGAAGAG 
GCAGAACGTC AAGCAAAGAA CTTGCCTAAA GCTGATAAGA AGGCAGTTAT CCAGCATTTC 
CAGGAGAAAG TGGAATCTTT GGAACAGGAA GCAGCCAACG AGAGACAGCA GCTGGTGGAG 
ACACACATGG CCAGAGTGGA AGCCATGCTC AATGACCGCC GCCGCCTGGC CCTGGAGAAC 
TACATCACCG CTCTGCAGGC TGTTCCTCCT CGGCCTCGTC ACGTGTTCAA TATGCTAAAG 
AAGTATGTCC GCGCAGAACA GAAGGACAGA CAGCACACCC TAAAGCATTT CGAGCATGTG 
CGCATGGTGG ATCCCAAGAA AGCCGCTCAG ATCCGGTCCC AGGTTATGAC ACACCTCCGT 
GTGATTTATG AGCGCATGAA TCAGTCTCTC TCCCTGCTCT ACAACGTGCC TGCAGTGGCC 
GAGGAGATTC AGGATGAAGT TGATGAGCTG CTTCAGAAAG AGCAAAACTA TTCAGATGAC 
GTCTTGGCCA ACATGATTAG TGAACCAAGG ATCAGTTACG GAAACGATGC TCTCATGCCA 
TCTTTGACCG AAACGAAAAC CACCGTGGAG CTCCTTCCCG TGAATGGAGA GTTCAGCCTG 
GACGATCTCC AGCCGTGGCA TTCTTTTGGG GCTGACTCTG TGCCAGCCAA CACAGAAAAC 
GAAGTTGAGC CTGTTGATGC CCGCCCTGCT GCCGACCGAG GACTGACCAC TCGACCAGGT 
TCTGGGTTGA CAAATATCAA GACGGAGGAG ATCTCTGAAG TGAAGATGGA TGCAGAATTC 
CGACATGACT CAGGATATGA AGTTCATCAT CAAAAATTGG TGTTCTTTGC AGAAGATGTG 
GGTTCAAACA AAGGTGCAAT CATTGGACTC ATGGTGGGCG GTGTTGTCAT AGCGACAGTG 
ATCGTCATCA CCTTGGTGAT GCTGAAGAAG AAACAGTACA CATCCATTCA TCATGGTGTG 
GTGGAGGTTG ACGCCGCTGT CACCCCAGAG GAGCGCCACC TGTCCAAGAT GCAGCAGAAC 
GGCTACGAAA ATCCAACCTA CAAGTTCTTT GAGCAGATGC AGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_958817.1
CDS	151..2238
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_201414.3
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201414.3

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGTTCCT ACAACAGCAG CCAGTACCCC TGATGCCGTT 
GACAAGTATC TCGAGACACC TGGGGATGAG AATGAACATG CCCATTTCCA GAAAGCCAAA 
GAGAGGCTTG AGGCCAAGCA CCGAGAGAGA ATGTCCCAGG TCATGAGAGA ATGGGAAGAG 
GCAGAACGTC AAGCAAAGAA CTTGCCTAAA GCTGATAAGA AGGCAGTTAT CCAGCATTTC 
CAGGAGAAAG TGGAATCTTT GGAACAGGAA GCAGCCAACG AGAGACAGCA GCTGGTGGAG 
ACACACATGG CCAGAGTGGA AGCCATGCTC AATGACCGCC GCCGCCTGGC CCTGGAGAAC 
TACATCACCG CTCTGCAGGC TGTTCCTCCT CGGCCTCGTC ACGTGTTCAA TATGCTAAAG 
AAGTATGTCC GCGCAGAACA GAAGGACAGA CAGCACACCC TAAAGCATTT CGAGCATGTG 
CGCATGGTGG ATCCCAAGAA AGCCGCTCAG ATCCGGTCCC AGGTTATGAC ACACCTCCGT 
GTGATTTATG AGCGCATGAA TCAGTCTCTC TCCCTGCTCT ACAACGTGCC TGCAGTGGCC 
GAGGAGATTC AGGATGAAGT TGATGAGCTG CTTCAGAAAG AGCAAAACTA TTCAGATGAC 
GTCTTGGCCA ACATGATTAG TGAACCAAGG ATCAGTTACG GAAACGATGC TCTCATGCCA 
TCTTTGACCG AAACGAAAAC CACCGTGGAG CTCCTTCCCG TGAATGGAGA GTTCAGCCTG 
GACGATCTCC AGCCGTGGCA TTCTTTTGGG GCTGACTCTG TGCCAGCCAA CACAGAAAAC 
GAAGTTGAGC CTGTTGATGC CCGCCCTGCT GCCGACCGAG GACTGACCAC TCGACCAGGT 
TCTGGGTTGA CAAATATCAA GACGGAGGAG ATCTCTGAAG TGAAGATGGA TGCAGAATTC 
CGACATGACT CAGGATATGA AGTTCATCAT CAAAAATTGG TGTTCTTTGC AGAAGATGTG 
GGTTCAAACA AAGGTGCAAT CATTGGACTC ATGGTGGGCG GTGTTGTCAT AGCGACAGTG 
ATCGTCATCA CCTTGGTGAT GCTGAAGAAG AAACAGTACA CATCCATTCA TCATGGTGTG 
GTGGAGGTTG ACGCCGCTGT CACCCCAGAG GAGCGCCACC TGTCCAAGAT GCAGCAGAAC 
GGCTACGAAA ATCCAACCTA CAAGTTCTTT GAGCAGATGC AGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_201414.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_958817.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu26689
Clone ID Related Accession (Same CDS sequence)	NM_201414.3 , NM_201414.2
Accession Version	NM_201414.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2088bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, Y00264.1 and BM876312.1. On Apr 29, 2009 this sequence version replaced NM_201414.1. Transcript Variant: This variant (3) lacks an alternate in-frame segment compared to variant 1. The resulting isoform (c, also known as PreA4 695) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.124159.1, SRR1803611.87333.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGTTCCT ACAACAGCAG CCAGTACCCC TGATGCCGTT 
GACAAGTATC TCGAGACACC TGGGGATGAG AATGAACATG CCCATTTCCA GAAAGCCAAA 
GAGAGGCTTG AGGCCAAGCA CCGAGAGAGA ATGTCCCAGG TCATGAGAGA ATGGGAAGAG 
GCAGAACGTC AAGCAAAGAA CTTGCCTAAA GCTGATAAGA AGGCAGTTAT CCAGCATTTC 
CAGGAGAAAG TGGAATCTTT GGAACAGGAA GCAGCCAACG AGAGACAGCA GCTGGTGGAG 
ACACACATGG CCAGAGTGGA AGCCATGCTC AATGACCGCC GCCGCCTGGC CCTGGAGAAC 
TACATCACCG CTCTGCAGGC TGTTCCTCCT CGGCCTCGTC ACGTGTTCAA TATGCTAAAG 
AAGTATGTCC GCGCAGAACA GAAGGACAGA CAGCACACCC TAAAGCATTT CGAGCATGTG 
CGCATGGTGG ATCCCAAGAA AGCCGCTCAG ATCCGGTCCC AGGTTATGAC ACACCTCCGT 
GTGATTTATG AGCGCATGAA TCAGTCTCTC TCCCTGCTCT ACAACGTGCC TGCAGTGGCC 
GAGGAGATTC AGGATGAAGT TGATGAGCTG CTTCAGAAAG AGCAAAACTA TTCAGATGAC 
GTCTTGGCCA ACATGATTAG TGAACCAAGG ATCAGTTACG GAAACGATGC TCTCATGCCA 
TCTTTGACCG AAACGAAAAC CACCGTGGAG CTCCTTCCCG TGAATGGAGA GTTCAGCCTG 
GACGATCTCC AGCCGTGGCA TTCTTTTGGG GCTGACTCTG TGCCAGCCAA CACAGAAAAC 
GAAGTTGAGC CTGTTGATGC CCGCCCTGCT GCCGACCGAG GACTGACCAC TCGACCAGGT 
TCTGGGTTGA CAAATATCAA GACGGAGGAG ATCTCTGAAG TGAAGATGGA TGCAGAATTC 
CGACATGACT CAGGATATGA AGTTCATCAT CAAAAATTGG TGTTCTTTGC AGAAGATGTG 
GGTTCAAACA AAGGTGCAAT CATTGGACTC ATGGTGGGCG GTGTTGTCAT AGCGACAGTG 
ATCGTCATCA CCTTGGTGAT GCTGAAGAAG AAACAGTACA CATCCATTCA TCATGGTGTG 
GTGGAGGTTG ACGCCGCTGT CACCCCAGAG GAGCGCCACC TGTCCAAGAT GCAGCAGAAC 
GGCTACGAAA ATCCAACCTA CAAGTTCTTT GAGCAGATGC AGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_958817.1
CDS	201..2288
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_201414.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201414.2

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGTTCCT ACAACAGCAG CCAGTACCCC TGATGCCGTT 
GACAAGTATC TCGAGACACC TGGGGATGAG AATGAACATG CCCATTTCCA GAAAGCCAAA 
GAGAGGCTTG AGGCCAAGCA CCGAGAGAGA ATGTCCCAGG TCATGAGAGA ATGGGAAGAG 
GCAGAACGTC AAGCAAAGAA CTTGCCTAAA GCTGATAAGA AGGCAGTTAT CCAGCATTTC 
CAGGAGAAAG TGGAATCTTT GGAACAGGAA GCAGCCAACG AGAGACAGCA GCTGGTGGAG 
ACACACATGG CCAGAGTGGA AGCCATGCTC AATGACCGCC GCCGCCTGGC CCTGGAGAAC 
TACATCACCG CTCTGCAGGC TGTTCCTCCT CGGCCTCGTC ACGTGTTCAA TATGCTAAAG 
AAGTATGTCC GCGCAGAACA GAAGGACAGA CAGCACACCC TAAAGCATTT CGAGCATGTG 
CGCATGGTGG ATCCCAAGAA AGCCGCTCAG ATCCGGTCCC AGGTTATGAC ACACCTCCGT 
GTGATTTATG AGCGCATGAA TCAGTCTCTC TCCCTGCTCT ACAACGTGCC TGCAGTGGCC 
GAGGAGATTC AGGATGAAGT TGATGAGCTG CTTCAGAAAG AGCAAAACTA TTCAGATGAC 
GTCTTGGCCA ACATGATTAG TGAACCAAGG ATCAGTTACG GAAACGATGC TCTCATGCCA 
TCTTTGACCG AAACGAAAAC CACCGTGGAG CTCCTTCCCG TGAATGGAGA GTTCAGCCTG 
GACGATCTCC AGCCGTGGCA TTCTTTTGGG GCTGACTCTG TGCCAGCCAA CACAGAAAAC 
GAAGTTGAGC CTGTTGATGC CCGCCCTGCT GCCGACCGAG GACTGACCAC TCGACCAGGT 
TCTGGGTTGA CAAATATCAA GACGGAGGAG ATCTCTGAAG TGAAGATGGA TGCAGAATTC 
CGACATGACT CAGGATATGA AGTTCATCAT CAAAAATTGG TGTTCTTTGC AGAAGATGTG 
GGTTCAAACA AAGGTGCAAT CATTGGACTC ATGGTGGGCG GTGTTGTCAT AGCGACAGTG 
ATCGTCATCA CCTTGGTGAT GCTGAAGAAG AAACAGTACA CATCCATTCA TCATGGTGTG 
GTGGAGGTTG ACGCCGCTGT CACCCCAGAG GAGCGCCACC TGTCCAAGAT GCAGCAGAAC 
GGCTACGAAA ATCCAACCTA CAAGTTCTTT GAGCAGATGC AGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_201413.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_958816.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu26762
Clone ID Related Accession (Same CDS sequence)	NM_201413.2 , NM_201413.3
Accession Version	NM_201413.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2256bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, BC065529.1 and BM876312.1. On Apr 29, 2009 this sequence version replaced NM_201413.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b, also known as PreA4 751) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.69071.1, SRR1660803.20598.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATTCCTAC AACAGCAGCC AGTACCCCTG ATGCCGTTGA CAAGTATCTC 
GAGACACCTG GGGATGAGAA TGAACATGCC CATTTCCAGA AAGCCAAAGA GAGGCTTGAG 
GCCAAGCACC GAGAGAGAAT GTCCCAGGTC ATGAGAGAAT GGGAAGAGGC AGAACGTCAA 
GCAAAGAACT TGCCTAAAGC TGATAAGAAG GCAGTTATCC AGCATTTCCA GGAGAAAGTG 
GAATCTTTGG AACAGGAAGC AGCCAACGAG AGACAGCAGC TGGTGGAGAC ACACATGGCC 
AGAGTGGAAG CCATGCTCAA TGACCGCCGC CGCCTGGCCC TGGAGAACTA CATCACCGCT 
CTGCAGGCTG TTCCTCCTCG GCCTCGTCAC GTGTTCAATA TGCTAAAGAA GTATGTCCGC 
GCAGAACAGA AGGACAGACA GCACACCCTA AAGCATTTCG AGCATGTGCG CATGGTGGAT 
CCCAAGAAAG CCGCTCAGAT CCGGTCCCAG GTTATGACAC ACCTCCGTGT GATTTATGAG 
CGCATGAATC AGTCTCTCTC CCTGCTCTAC AACGTGCCTG CAGTGGCCGA GGAGATTCAG 
GATGAAGTTG ATGAGCTGCT TCAGAAAGAG CAAAACTATT CAGATGACGT CTTGGCCAAC 
ATGATTAGTG AACCAAGGAT CAGTTACGGA AACGATGCTC TCATGCCATC TTTGACCGAA 
ACGAAAACCA CCGTGGAGCT CCTTCCCGTG AATGGAGAGT TCAGCCTGGA CGATCTCCAG 
CCGTGGCATT CTTTTGGGGC TGACTCTGTG CCAGCCAACA CAGAAAACGA AGTTGAGCCT 
GTTGATGCCC GCCCTGCTGC CGACCGAGGA CTGACCACTC GACCAGGTTC TGGGTTGACA 
AATATCAAGA CGGAGGAGAT CTCTGAAGTG AAGATGGATG CAGAATTCCG ACATGACTCA 
GGATATGAAG TTCATCATCA AAAATTGGTG TTCTTTGCAG AAGATGTGGG TTCAAACAAA 
GGTGCAATCA TTGGACTCAT GGTGGGCGGT GTTGTCATAG CGACAGTGAT CGTCATCACC 
TTGGTGATGC TGAAGAAGAA ACAGTACACA TCCATTCATC ATGGTGTGGT GGAGGTTGAC 
GCCGCTGTCA CCCCAGAGGA GCGCCACCTG TCCAAGATGC AGCAGAACGG CTACGAAAAT 
CCAACCTACA AGTTCTTTGA GCAGATGCAG AACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_958816.1
CDS	201..2456
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_201413.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201413.2

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATTCCTAC AACAGCAGCC AGTACCCCTG ATGCCGTTGA CAAGTATCTC 
GAGACACCTG GGGATGAGAA TGAACATGCC CATTTCCAGA AAGCCAAAGA GAGGCTTGAG 
GCCAAGCACC GAGAGAGAAT GTCCCAGGTC ATGAGAGAAT GGGAAGAGGC AGAACGTCAA 
GCAAAGAACT TGCCTAAAGC TGATAAGAAG GCAGTTATCC AGCATTTCCA GGAGAAAGTG 
GAATCTTTGG AACAGGAAGC AGCCAACGAG AGACAGCAGC TGGTGGAGAC ACACATGGCC 
AGAGTGGAAG CCATGCTCAA TGACCGCCGC CGCCTGGCCC TGGAGAACTA CATCACCGCT 
CTGCAGGCTG TTCCTCCTCG GCCTCGTCAC GTGTTCAATA TGCTAAAGAA GTATGTCCGC 
GCAGAACAGA AGGACAGACA GCACACCCTA AAGCATTTCG AGCATGTGCG CATGGTGGAT 
CCCAAGAAAG CCGCTCAGAT CCGGTCCCAG GTTATGACAC ACCTCCGTGT GATTTATGAG 
CGCATGAATC AGTCTCTCTC CCTGCTCTAC AACGTGCCTG CAGTGGCCGA GGAGATTCAG 
GATGAAGTTG ATGAGCTGCT TCAGAAAGAG CAAAACTATT CAGATGACGT CTTGGCCAAC 
ATGATTAGTG AACCAAGGAT CAGTTACGGA AACGATGCTC TCATGCCATC TTTGACCGAA 
ACGAAAACCA CCGTGGAGCT CCTTCCCGTG AATGGAGAGT TCAGCCTGGA CGATCTCCAG 
CCGTGGCATT CTTTTGGGGC TGACTCTGTG CCAGCCAACA CAGAAAACGA AGTTGAGCCT 
GTTGATGCCC GCCCTGCTGC CGACCGAGGA CTGACCACTC GACCAGGTTC TGGGTTGACA 
AATATCAAGA CGGAGGAGAT CTCTGAAGTG AAGATGGATG CAGAATTCCG ACATGACTCA 
GGATATGAAG TTCATCATCA AAAATTGGTG TTCTTTGCAG AAGATGTGGG TTCAAACAAA 
GGTGCAATCA TTGGACTCAT GGTGGGCGGT GTTGTCATAG CGACAGTGAT CGTCATCACC 
TTGGTGATGC TGAAGAAGAA ACAGTACACA TCCATTCATC ATGGTGTGGT GGAGGTTGAC 
GCCGCTGTCA CCCCAGAGGA GCGCCACCTG TCCAAGATGC AGCAGAACGG CTACGAAAAT 
CCAACCTACA AGTTCTTTGA GCAGATGCAG AACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_201413.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_958816.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 2, mRNA.

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CloneID	OHu26762
Clone ID Related Accession (Same CDS sequence)	NM_201413.2 , NM_201413.3
Accession Version	NM_201413.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2256bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, BC065529.1 and BM876312.1. On May 31, 2019 this sequence version replaced NM_201413.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b, also known as PreA4 751) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.197914.1, SRR1660807.142014.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATTCCTAC AACAGCAGCC AGTACCCCTG ATGCCGTTGA CAAGTATCTC 
GAGACACCTG GGGATGAGAA TGAACATGCC CATTTCCAGA AAGCCAAAGA GAGGCTTGAG 
GCCAAGCACC GAGAGAGAAT GTCCCAGGTC ATGAGAGAAT GGGAAGAGGC AGAACGTCAA 
GCAAAGAACT TGCCTAAAGC TGATAAGAAG GCAGTTATCC AGCATTTCCA GGAGAAAGTG 
GAATCTTTGG AACAGGAAGC AGCCAACGAG AGACAGCAGC TGGTGGAGAC ACACATGGCC 
AGAGTGGAAG CCATGCTCAA TGACCGCCGC CGCCTGGCCC TGGAGAACTA CATCACCGCT 
CTGCAGGCTG TTCCTCCTCG GCCTCGTCAC GTGTTCAATA TGCTAAAGAA GTATGTCCGC 
GCAGAACAGA AGGACAGACA GCACACCCTA AAGCATTTCG AGCATGTGCG CATGGTGGAT 
CCCAAGAAAG CCGCTCAGAT CCGGTCCCAG GTTATGACAC ACCTCCGTGT GATTTATGAG 
CGCATGAATC AGTCTCTCTC CCTGCTCTAC AACGTGCCTG CAGTGGCCGA GGAGATTCAG 
GATGAAGTTG ATGAGCTGCT TCAGAAAGAG CAAAACTATT CAGATGACGT CTTGGCCAAC 
ATGATTAGTG AACCAAGGAT CAGTTACGGA AACGATGCTC TCATGCCATC TTTGACCGAA 
ACGAAAACCA CCGTGGAGCT CCTTCCCGTG AATGGAGAGT TCAGCCTGGA CGATCTCCAG 
CCGTGGCATT CTTTTGGGGC TGACTCTGTG CCAGCCAACA CAGAAAACGA AGTTGAGCCT 
GTTGATGCCC GCCCTGCTGC CGACCGAGGA CTGACCACTC GACCAGGTTC TGGGTTGACA 
AATATCAAGA CGGAGGAGAT CTCTGAAGTG AAGATGGATG CAGAATTCCG ACATGACTCA 
GGATATGAAG TTCATCATCA AAAATTGGTG TTCTTTGCAG AAGATGTGGG TTCAAACAAA 
GGTGCAATCA TTGGACTCAT GGTGGGCGGT GTTGTCATAG CGACAGTGAT CGTCATCACC 
TTGGTGATGC TGAAGAAGAA ACAGTACACA TCCATTCATC ATGGTGTGGT GGAGGTTGAC 
GCCGCTGTCA CCCCAGAGGA GCGCCACCTG TCCAAGATGC AGCAGAACGG CTACGAAAAT 
CCAACCTACA AGTTCTTTGA GCAGATGCAG AACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_958816.1
CDS	151..2406
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_201413.3
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201413.3

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATTCCTAC AACAGCAGCC AGTACCCCTG ATGCCGTTGA CAAGTATCTC 
GAGACACCTG GGGATGAGAA TGAACATGCC CATTTCCAGA AAGCCAAAGA GAGGCTTGAG 
GCCAAGCACC GAGAGAGAAT GTCCCAGGTC ATGAGAGAAT GGGAAGAGGC AGAACGTCAA 
GCAAAGAACT TGCCTAAAGC TGATAAGAAG GCAGTTATCC AGCATTTCCA GGAGAAAGTG 
GAATCTTTGG AACAGGAAGC AGCCAACGAG AGACAGCAGC TGGTGGAGAC ACACATGGCC 
AGAGTGGAAG CCATGCTCAA TGACCGCCGC CGCCTGGCCC TGGAGAACTA CATCACCGCT 
CTGCAGGCTG TTCCTCCTCG GCCTCGTCAC GTGTTCAATA TGCTAAAGAA GTATGTCCGC 
GCAGAACAGA AGGACAGACA GCACACCCTA AAGCATTTCG AGCATGTGCG CATGGTGGAT 
CCCAAGAAAG CCGCTCAGAT CCGGTCCCAG GTTATGACAC ACCTCCGTGT GATTTATGAG 
CGCATGAATC AGTCTCTCTC CCTGCTCTAC AACGTGCCTG CAGTGGCCGA GGAGATTCAG 
GATGAAGTTG ATGAGCTGCT TCAGAAAGAG CAAAACTATT CAGATGACGT CTTGGCCAAC 
ATGATTAGTG AACCAAGGAT CAGTTACGGA AACGATGCTC TCATGCCATC TTTGACCGAA 
ACGAAAACCA CCGTGGAGCT CCTTCCCGTG AATGGAGAGT TCAGCCTGGA CGATCTCCAG 
CCGTGGCATT CTTTTGGGGC TGACTCTGTG CCAGCCAACA CAGAAAACGA AGTTGAGCCT 
GTTGATGCCC GCCCTGCTGC CGACCGAGGA CTGACCACTC GACCAGGTTC TGGGTTGACA 
AATATCAAGA CGGAGGAGAT CTCTGAAGTG AAGATGGATG CAGAATTCCG ACATGACTCA 
GGATATGAAG TTCATCATCA AAAATTGGTG TTCTTTGCAG AAGATGTGGG TTCAAACAAA 
GGTGCAATCA TTGGACTCAT GGTGGGCGGT GTTGTCATAG CGACAGTGAT CGTCATCACC 
TTGGTGATGC TGAAGAAGAA ACAGTACACA TCCATTCATC ATGGTGTGGT GGAGGTTGAC 
GCCGCTGTCA CCCCAGAGGA GCGCCACCTG TCCAAGATGC AGCAGAACGG CTACGAAAAT 
CCAACCTACA AGTTCTTTGA GCAGATGCAG AACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_001136129.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129601.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu27126
Clone ID Related Accession (Same CDS sequence)	NM_001136129.3 , NM_001136129.2
Accession Version	NM_001136129.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1920bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform e precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, AF282245.1, BC065529.1 and BM876312.1. On May 31, 2019 this sequence version replaced NM_001136129.2. Transcript Variant: This variant (5) lacks three alternate in-frame exons compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF282245.1, SRR3476690.941721.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTC 
TACCCTGAAC TGCAGATCAC CAATGTGGTA GAAGCCAACC AACCAGTGAC CATCCAGAAC 
TGGTGCAAGC GGGGCCGCAA GCAGTGCAAG ACCCATCCCC ACTTTGTGAT TCCCTACCGC 
TGCTTAGTTG GTGAGTTTGT AAGTGATGCC CTTCTCGTTC CTGACAAGTG CAAATTCTTA 
CACCAGGAGA GGATGGATGT TTGCGAAACT CATCTTCACT GGCACACCGT CGCCAAAGAG 
ACATGCAGTG AGAAGAGTAC CAACTTGCAT GACTACGGCA TGTTGCTGCC CTGCGGAATT 
GACAAGTTCC GAGGGGTAGA GTTTGTGTGT TGCCCACTGG CTGAAGAAAG TGACAATGTG 
GATTCTGCTG ATGCGGAGGA GGATGACTCG GATGTCTGGT GGGGCGGAGC AGACACAGAC 
TATGCAGATG GGAGTGAAGA CAAAGTAGTA GAAGTAGCAG AGGAGGAAGA AGTGGCTGAG 
GTGGAAGAAG AAGAAGCCGA TGATGACGAG GACGATGAGG ATGGTGATGA GGTAGAGGAA 
GAGGCTGAGG AACCCTACGA AGAAGCCACA GAGAGAACCA CCAGCATTGC CACCACCACC 
ACCACCACCA CAGAGTCTGT GGAAGAGGTG GTTCGAGTTC CTACAACAGC AGCCAGTACC 
CCTGATGCCG TTGACAAGTA TCTCGAGACA CCTGGGGATG AGAATGAACA TGCCCATTTC 
CAGAAAGCCA AAGAGAGGCT TGAGGCCAAG CACCGAGAGA GAATGTCCCA GGTCATGAGA 
GAATGGGAAG AGGCAGAACG TCAAGCAAAG AACTTGCCTA AAGCTGATAA GAAGGCAGTT 
ATCCAGCATT TCCAGGAGAA AGTGGAATCT TTGGAACAGG AAGCAGCCAA CGAGAGACAG 
CAGCTGGTGG AGACACACAT GGCCAGAGTG GAAGCCATGC TCAATGACCG CCGCCGCCTG 
GCCCTGGAGA ACTACATCAC CGCTCTGCAG GCTGTTCCTC CTCGGCCTCG TCACGTGTTC 
AATATGCTAA AGAAGTATGT CCGCGCAGAA CAGAAGGACA GACAGCACAC CCTAAAGCAT 
TTCGAGCATG TGCGCATGGT GGATCCCAAG AAAGCCGCTC AGATCCGGTC CCAGGTTATG 
ACACACCTCC GTGTGATTTA TGAGCGCATG AATCAGTCTC TCTCCCTGCT CTACAACGTG 
CCTGCAGTGG CCGAGGAGAT TCAGGATGAA GTTGATGAGC TGCTTCAGAA AGAGCAAAAC 
TATTCAGATG ACGTCTTGGC CAACATGATT AGTGAACCAA GGATCAGTTA CGGAAACGAT 
GCTCTCATGC CATCTTTGAC CGAAACGAAA ACCACCGTGG AGCTCCTTCC CGTGAATGGA 
GAGTTCAGCC TGGACGATCT CCAGCCGTGG CATTCTTTTG GGGCTGACTC TGTGCCAGCC 
AACACAGAAA ACGAAGTTGA GCCTGTTGAT GCCCGCCCTG CTGCCGACCG AGGACTGACC 
ACTCGACCAG GTTCTGGGTT GACAAATATC AAGACGGAGG AGATCTCTGA AGTGAAGATG 
GATGCAGAAT TCCGACATGA CTCAGGATAT GAAGTTCATC ATCAAAAATT GGTGTTCTTT 
GCAGAAGATG TGGGTTCAAA CAAAGGTGCA ATCATTGGAC TCATGGTGGG CGGTGTTGTC 
ATAGCGACAG TGATCGTCAT CACCTTGGTG ATGCTGAAGA AGAAACAGTA CACATCCATT 
CATCATGGTG TGGTGGAGGT TGACGCCGCT GTCACCCCAG AGGAGCGCCA CCTGTCCAAG 
ATGCAGCAGA ACGGCTACGA AAATCCAACC TACAAGTTCT TTGAGCAGAT GCAGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129601.1
CDS	151..2070
Translation	MLPGLALLLLAAWTARALEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_001136129.3
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001136129.3

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTC 
TACCCTGAAC TGCAGATCAC CAATGTGGTA GAAGCCAACC AACCAGTGAC CATCCAGAAC 
TGGTGCAAGC GGGGCCGCAA GCAGTGCAAG ACCCATCCCC ACTTTGTGAT TCCCTACCGC 
TGCTTAGTTG GTGAGTTTGT AAGTGATGCC CTTCTCGTTC CTGACAAGTG CAAATTCTTA 
CACCAGGAGA GGATGGATGT TTGCGAAACT CATCTTCACT GGCACACCGT CGCCAAAGAG 
ACATGCAGTG AGAAGAGTAC CAACTTGCAT GACTACGGCA TGTTGCTGCC CTGCGGAATT 
GACAAGTTCC GAGGGGTAGA GTTTGTGTGT TGCCCACTGG CTGAAGAAAG TGACAATGTG 
GATTCTGCTG ATGCGGAGGA GGATGACTCG GATGTCTGGT GGGGCGGAGC AGACACAGAC 
TATGCAGATG GGAGTGAAGA CAAAGTAGTA GAAGTAGCAG AGGAGGAAGA AGTGGCTGAG 
GTGGAAGAAG AAGAAGCCGA TGATGACGAG GACGATGAGG ATGGTGATGA GGTAGAGGAA 
GAGGCTGAGG AACCCTACGA AGAAGCCACA GAGAGAACCA CCAGCATTGC CACCACCACC 
ACCACCACCA CAGAGTCTGT GGAAGAGGTG GTTCGAGTTC CTACAACAGC AGCCAGTACC 
CCTGATGCCG TTGACAAGTA TCTCGAGACA CCTGGGGATG AGAATGAACA TGCCCATTTC 
CAGAAAGCCA AAGAGAGGCT TGAGGCCAAG CACCGAGAGA GAATGTCCCA GGTCATGAGA 
GAATGGGAAG AGGCAGAACG TCAAGCAAAG AACTTGCCTA AAGCTGATAA GAAGGCAGTT 
ATCCAGCATT TCCAGGAGAA AGTGGAATCT TTGGAACAGG AAGCAGCCAA CGAGAGACAG 
CAGCTGGTGG AGACACACAT GGCCAGAGTG GAAGCCATGC TCAATGACCG CCGCCGCCTG 
GCCCTGGAGA ACTACATCAC CGCTCTGCAG GCTGTTCCTC CTCGGCCTCG TCACGTGTTC 
AATATGCTAA AGAAGTATGT CCGCGCAGAA CAGAAGGACA GACAGCACAC CCTAAAGCAT 
TTCGAGCATG TGCGCATGGT GGATCCCAAG AAAGCCGCTC AGATCCGGTC CCAGGTTATG 
ACACACCTCC GTGTGATTTA TGAGCGCATG AATCAGTCTC TCTCCCTGCT CTACAACGTG 
CCTGCAGTGG CCGAGGAGAT TCAGGATGAA GTTGATGAGC TGCTTCAGAA AGAGCAAAAC 
TATTCAGATG ACGTCTTGGC CAACATGATT AGTGAACCAA GGATCAGTTA CGGAAACGAT 
GCTCTCATGC CATCTTTGAC CGAAACGAAA ACCACCGTGG AGCTCCTTCC CGTGAATGGA 
GAGTTCAGCC TGGACGATCT CCAGCCGTGG CATTCTTTTG GGGCTGACTC TGTGCCAGCC 
AACACAGAAA ACGAAGTTGA GCCTGTTGAT GCCCGCCCTG CTGCCGACCG AGGACTGACC 
ACTCGACCAG GTTCTGGGTT GACAAATATC AAGACGGAGG AGATCTCTGA AGTGAAGATG 
GATGCAGAAT TCCGACATGA CTCAGGATAT GAAGTTCATC ATCAAAAATT GGTGTTCTTT 
GCAGAAGATG TGGGTTCAAA CAAAGGTGCA ATCATTGGAC TCATGGTGGG CGGTGTTGTC 
ATAGCGACAG TGATCGTCAT CACCTTGGTG ATGCTGAAGA AGAAACAGTA CACATCCATT 
CATCATGGTG TGGTGGAGGT TGACGCCGCT GTCACCCCAG AGGAGCGCCA CCTGTCCAAG 
ATGCAGCAGA ACGGCTACGA AAATCCAACC TACAAGTTCT TTGAGCAGAT GCAGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_001136129.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129601.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 5, mRNA.

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CloneID	OHu27126
Clone ID Related Accession (Same CDS sequence)	NM_001136129.3 , NM_001136129.2
Accession Version	NM_001136129.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1920bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform e precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, AF282245.1, BC065529.1 and BM876312.1. On Apr 29, 2009 this sequence version replaced NM_001136129.1. Transcript Variant: This variant (5) lacks three alternate in-frame exons compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF282245.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTC 
TACCCTGAAC TGCAGATCAC CAATGTGGTA GAAGCCAACC AACCAGTGAC CATCCAGAAC 
TGGTGCAAGC GGGGCCGCAA GCAGTGCAAG ACCCATCCCC ACTTTGTGAT TCCCTACCGC 
TGCTTAGTTG GTGAGTTTGT AAGTGATGCC CTTCTCGTTC CTGACAAGTG CAAATTCTTA 
CACCAGGAGA GGATGGATGT TTGCGAAACT CATCTTCACT GGCACACCGT CGCCAAAGAG 
ACATGCAGTG AGAAGAGTAC CAACTTGCAT GACTACGGCA TGTTGCTGCC CTGCGGAATT 
GACAAGTTCC GAGGGGTAGA GTTTGTGTGT TGCCCACTGG CTGAAGAAAG TGACAATGTG 
GATTCTGCTG ATGCGGAGGA GGATGACTCG GATGTCTGGT GGGGCGGAGC AGACACAGAC 
TATGCAGATG GGAGTGAAGA CAAAGTAGTA GAAGTAGCAG AGGAGGAAGA AGTGGCTGAG 
GTGGAAGAAG AAGAAGCCGA TGATGACGAG GACGATGAGG ATGGTGATGA GGTAGAGGAA 
GAGGCTGAGG AACCCTACGA AGAAGCCACA GAGAGAACCA CCAGCATTGC CACCACCACC 
ACCACCACCA CAGAGTCTGT GGAAGAGGTG GTTCGAGTTC CTACAACAGC AGCCAGTACC 
CCTGATGCCG TTGACAAGTA TCTCGAGACA CCTGGGGATG AGAATGAACA TGCCCATTTC 
CAGAAAGCCA AAGAGAGGCT TGAGGCCAAG CACCGAGAGA GAATGTCCCA GGTCATGAGA 
GAATGGGAAG AGGCAGAACG TCAAGCAAAG AACTTGCCTA AAGCTGATAA GAAGGCAGTT 
ATCCAGCATT TCCAGGAGAA AGTGGAATCT TTGGAACAGG AAGCAGCCAA CGAGAGACAG 
CAGCTGGTGG AGACACACAT GGCCAGAGTG GAAGCCATGC TCAATGACCG CCGCCGCCTG 
GCCCTGGAGA ACTACATCAC CGCTCTGCAG GCTGTTCCTC CTCGGCCTCG TCACGTGTTC 
AATATGCTAA AGAAGTATGT CCGCGCAGAA CAGAAGGACA GACAGCACAC CCTAAAGCAT 
TTCGAGCATG TGCGCATGGT GGATCCCAAG AAAGCCGCTC AGATCCGGTC CCAGGTTATG 
ACACACCTCC GTGTGATTTA TGAGCGCATG AATCAGTCTC TCTCCCTGCT CTACAACGTG 
CCTGCAGTGG CCGAGGAGAT TCAGGATGAA GTTGATGAGC TGCTTCAGAA AGAGCAAAAC 
TATTCAGATG ACGTCTTGGC CAACATGATT AGTGAACCAA GGATCAGTTA CGGAAACGAT 
GCTCTCATGC CATCTTTGAC CGAAACGAAA ACCACCGTGG AGCTCCTTCC CGTGAATGGA 
GAGTTCAGCC TGGACGATCT CCAGCCGTGG CATTCTTTTG GGGCTGACTC TGTGCCAGCC 
AACACAGAAA ACGAAGTTGA GCCTGTTGAT GCCCGCCCTG CTGCCGACCG AGGACTGACC 
ACTCGACCAG GTTCTGGGTT GACAAATATC AAGACGGAGG AGATCTCTGA AGTGAAGATG 
GATGCAGAAT TCCGACATGA CTCAGGATAT GAAGTTCATC ATCAAAAATT GGTGTTCTTT 
GCAGAAGATG TGGGTTCAAA CAAAGGTGCA ATCATTGGAC TCATGGTGGG CGGTGTTGTC 
ATAGCGACAG TGATCGTCAT CACCTTGGTG ATGCTGAAGA AGAAACAGTA CACATCCATT 
CATCATGGTG TGGTGGAGGT TGACGCCGCT GTCACCCCAG AGGAGCGCCA CCTGTCCAAG 
ATGCAGCAGA ACGGCTACGA AAATCCAACC TACAAGTTCT TTGAGCAGAT GCAGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129601.1
CDS	201..2120
Translation	MLPGLALLLLAAWTARALEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_001136129.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001136129.2

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTC 
TACCCTGAAC TGCAGATCAC CAATGTGGTA GAAGCCAACC AACCAGTGAC CATCCAGAAC 
TGGTGCAAGC GGGGCCGCAA GCAGTGCAAG ACCCATCCCC ACTTTGTGAT TCCCTACCGC 
TGCTTAGTTG GTGAGTTTGT AAGTGATGCC CTTCTCGTTC CTGACAAGTG CAAATTCTTA 
CACCAGGAGA GGATGGATGT TTGCGAAACT CATCTTCACT GGCACACCGT CGCCAAAGAG 
ACATGCAGTG AGAAGAGTAC CAACTTGCAT GACTACGGCA TGTTGCTGCC CTGCGGAATT 
GACAAGTTCC GAGGGGTAGA GTTTGTGTGT TGCCCACTGG CTGAAGAAAG TGACAATGTG 
GATTCTGCTG ATGCGGAGGA GGATGACTCG GATGTCTGGT GGGGCGGAGC AGACACAGAC 
TATGCAGATG GGAGTGAAGA CAAAGTAGTA GAAGTAGCAG AGGAGGAAGA AGTGGCTGAG 
GTGGAAGAAG AAGAAGCCGA TGATGACGAG GACGATGAGG ATGGTGATGA GGTAGAGGAA 
GAGGCTGAGG AACCCTACGA AGAAGCCACA GAGAGAACCA CCAGCATTGC CACCACCACC 
ACCACCACCA CAGAGTCTGT GGAAGAGGTG GTTCGAGTTC CTACAACAGC AGCCAGTACC 
CCTGATGCCG TTGACAAGTA TCTCGAGACA CCTGGGGATG AGAATGAACA TGCCCATTTC 
CAGAAAGCCA AAGAGAGGCT TGAGGCCAAG CACCGAGAGA GAATGTCCCA GGTCATGAGA 
GAATGGGAAG AGGCAGAACG TCAAGCAAAG AACTTGCCTA AAGCTGATAA GAAGGCAGTT 
ATCCAGCATT TCCAGGAGAA AGTGGAATCT TTGGAACAGG AAGCAGCCAA CGAGAGACAG 
CAGCTGGTGG AGACACACAT GGCCAGAGTG GAAGCCATGC TCAATGACCG CCGCCGCCTG 
GCCCTGGAGA ACTACATCAC CGCTCTGCAG GCTGTTCCTC CTCGGCCTCG TCACGTGTTC 
AATATGCTAA AGAAGTATGT CCGCGCAGAA CAGAAGGACA GACAGCACAC CCTAAAGCAT 
TTCGAGCATG TGCGCATGGT GGATCCCAAG AAAGCCGCTC AGATCCGGTC CCAGGTTATG 
ACACACCTCC GTGTGATTTA TGAGCGCATG AATCAGTCTC TCTCCCTGCT CTACAACGTG 
CCTGCAGTGG CCGAGGAGAT TCAGGATGAA GTTGATGAGC TGCTTCAGAA AGAGCAAAAC 
TATTCAGATG ACGTCTTGGC CAACATGATT AGTGAACCAA GGATCAGTTA CGGAAACGAT 
GCTCTCATGC CATCTTTGAC CGAAACGAAA ACCACCGTGG AGCTCCTTCC CGTGAATGGA 
GAGTTCAGCC TGGACGATCT CCAGCCGTGG CATTCTTTTG GGGCTGACTC TGTGCCAGCC 
AACACAGAAA ACGAAGTTGA GCCTGTTGAT GCCCGCCCTG CTGCCGACCG AGGACTGACC 
ACTCGACCAG GTTCTGGGTT GACAAATATC AAGACGGAGG AGATCTCTGA AGTGAAGATG 
GATGCAGAAT TCCGACATGA CTCAGGATAT GAAGTTCATC ATCAAAAATT GGTGTTCTTT 
GCAGAAGATG TGGGTTCAAA CAAAGGTGCA ATCATTGGAC TCATGGTGGG CGGTGTTGTC 
ATAGCGACAG TGATCGTCAT CACCTTGGTG ATGCTGAAGA AGAAACAGTA CACATCCATT 
CATCATGGTG TGGTGGAGGT TGACGCCGCT GTCACCCCAG AGGAGCGCCA CCTGTCCAAG 
ATGCAGCAGA ACGGCTACGA AAATCCAACC TACAAGTTCT TTGAGCAGAT GCAGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_001136131.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129603.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu27184
Clone ID Related Accession (Same CDS sequence)	NM_001136131.2
Accession Version	NM_001136131.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1983bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform g
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK296229.1, Y00264.1 and BM876312.1. On Feb 24, 2011 this sequence version replaced NM_001136131.1. Transcript Variant: This variant (7) differs in the 5' UTR and coding sequence and lacks two alternate in-frame exons compared to variant 1. The resulting isoform (g) is shorter at the N-terminus and lacks an internal segment compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296229.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTTCTGTG GCAGACTGAA CATGCACATG AATGTCCAGA ATGGGAAGTG GGATTCAGAT 
CCATCAGGGA CCAAAACCTG CATTGATACC AAGGAAGGCA TCCTGCAGTA TTGCCAAGAA 
GTCTACCCTG AACTGCAGAT CACCAATGTG GTAGAAGCCA ACCAACCAGT GACCATCCAG 
AACTGGTGCA AGCGGGGCCG CAAGCAGTGC AAGACCCATC CCCACTTTGT GATTCCCTAC 
CGCTGCTTAG TTGGTGAGTT TGTAAGTGAT GCCCTTCTCG TTCCTGACAA GTGCAAATTC 
TTACACCAGG AGAGGATGGA TGTTTGCGAA ACTCATCTTC ACTGGCACAC CGTCGCCAAA 
GAGACATGCA GTGAGAAGAG TACCAACTTG CATGACTACG GCATGTTGCT GCCCTGCGGA 
ATTGACAAGT TCCGAGGGGT AGAGTTTGTG TGTTGCCCAC TGGCTGAAGA AAGTGACAAT 
GTGGATTCTG CTGATGCGGA GGAGGATGAC TCGGATGTCT GGTGGGGCGG AGCAGACACA 
GACTATGCAG ATGGGAGTGA AGACAAAGTA GTAGAAGTAG CAGAGGAGGA AGAAGTGGCT 
GAGGTGGAAG AAGAAGAAGC CGATGATGAC GAGGACGATG AGGATGGTGA TGAGGTAGAG 
GAAGAGGCTG AGGAACCCTA CGAAGAAGCC ACAGAGAGAA CCACCAGCAT TGCCACCACC 
ACCACCACCA CCACAGAGTC TGTGGAAGAG GTGGTTCGAG TTCCTACAAC AGCAGCCAGT 
ACCCCTGATG CCGTTGACAA GTATCTCGAG ACACCTGGGG ATGAGAATGA ACATGCCCAT 
TTCCAGAAAG CCAAAGAGAG GCTTGAGGCC AAGCACCGAG AGAGAATGTC CCAGGTCATG 
AGAGAATGGG AAGAGGCAGA ACGTCAAGCA AAGAACTTGC CTAAAGCTGA TAAGAAGGCA 
GTTATCCAGC ATTTCCAGGA GAAAGTGGAA TCTTTGGAAC AGGAAGCAGC CAACGAGAGA 
CAGCAGCTGG TGGAGACACA CATGGCCAGA GTGGAAGCCA TGCTCAATGA CCGCCGCCGC 
CTGGCCCTGG AGAACTACAT CACCGCTCTG CAGGCTGTTC CTCCTCGGCC TCGTCACGTG 
TTCAATATGC TAAAGAAGTA TGTCCGCGCA GAACAGAAGG ACAGACAGCA CACCCTAAAG 
CATTTCGAGC ATGTGCGCAT GGTGGATCCC AAGAAAGCCG CTCAGATCCG GTCCCAGGTT 
ATGACACACC TCCGTGTGAT TTATGAGCGC ATGAATCAGT CTCTCTCCCT GCTCTACAAC 
GTGCCTGCAG TGGCCGAGGA GATTCAGGAT GAAGTTGATG AGCTGCTTCA GAAAGAGCAA 
AACTATTCAG ATGACGTCTT GGCCAACATG ATTAGTGAAC CAAGGATCAG TTACGGAAAC 
GATGCTCTCA TGCCATCTTT GACCGAAACG AAAACCACCG TGGAGCTCCT TCCCGTGAAT 
GGAGAGTTCA GCCTGGACGA TCTCCAGCCG TGGCATTCTT TTGGGGCTGA CTCTGTGCCA 
GCCAACACAG AAAACGAAGT TGAGCCTGTT GATGCCCGCC CTGCTGCCGA CCGAGGACTG 
ACCACTCGAC CAGGTTCTGG GTTGACAAAT ATCAAGACGG AGGAGATCTC TGAAGTGAAG 
ATGGATGCAG AATTCCGACA TGACTCAGGA TATGAAGTTC ATCATCAAAA ATTGGTGTTC 
TTTGCAGAAG ATGTGGGTTC AAACAAAGGT GCAATCATTG GACTCATGGT GGGCGGTGTT 
GTCATAGCGA CAGTGATCGT CATCACCTTG GTGATGCTGA AGAAGAAACA GTACACATCC 
ATTCATCATG GTGTGGTGGA GGTTGACGCC GCTGTCACCC CAGAGGAGCG CCACCTGTCC 
AAGATGCAGC AGAACGGCTA CGAAAATCCA ACCTACAAGT TCTTTGAGCA GATGCAGAAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129603.1
CDS	193..2175
Translation	MFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_001136131.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001136131.2

ORF Insert Sequence:

ATGTTCTGTG GCAGACTGAA CATGCACATG AATGTCCAGA ATGGGAAGTG GGATTCAGAT 
CCATCAGGGA CCAAAACCTG CATTGATACC AAGGAAGGCA TCCTGCAGTA TTGCCAAGAA 
GTCTACCCTG AACTGCAGAT CACCAATGTG GTAGAAGCCA ACCAACCAGT GACCATCCAG 
AACTGGTGCA AGCGGGGCCG CAAGCAGTGC AAGACCCATC CCCACTTTGT GATTCCCTAC 
CGCTGCTTAG TTGGTGAGTT TGTAAGTGAT GCCCTTCTCG TTCCTGACAA GTGCAAATTC 
TTACACCAGG AGAGGATGGA TGTTTGCGAA ACTCATCTTC ACTGGCACAC CGTCGCCAAA 
GAGACATGCA GTGAGAAGAG TACCAACTTG CATGACTACG GCATGTTGCT GCCCTGCGGA 
ATTGACAAGT TCCGAGGGGT AGAGTTTGTG TGTTGCCCAC TGGCTGAAGA AAGTGACAAT 
GTGGATTCTG CTGATGCGGA GGAGGATGAC TCGGATGTCT GGTGGGGCGG AGCAGACACA 
GACTATGCAG ATGGGAGTGA AGACAAAGTA GTAGAAGTAG CAGAGGAGGA AGAAGTGGCT 
GAGGTGGAAG AAGAAGAAGC CGATGATGAC GAGGACGATG AGGATGGTGA TGAGGTAGAG 
GAAGAGGCTG AGGAACCCTA CGAAGAAGCC ACAGAGAGAA CCACCAGCAT TGCCACCACC 
ACCACCACCA CCACAGAGTC TGTGGAAGAG GTGGTTCGAG TTCCTACAAC AGCAGCCAGT 
ACCCCTGATG CCGTTGACAA GTATCTCGAG ACACCTGGGG ATGAGAATGA ACATGCCCAT 
TTCCAGAAAG CCAAAGAGAG GCTTGAGGCC AAGCACCGAG AGAGAATGTC CCAGGTCATG 
AGAGAATGGG AAGAGGCAGA ACGTCAAGCA AAGAACTTGC CTAAAGCTGA TAAGAAGGCA 
GTTATCCAGC ATTTCCAGGA GAAAGTGGAA TCTTTGGAAC AGGAAGCAGC CAACGAGAGA 
CAGCAGCTGG TGGAGACACA CATGGCCAGA GTGGAAGCCA TGCTCAATGA CCGCCGCCGC 
CTGGCCCTGG AGAACTACAT CACCGCTCTG CAGGCTGTTC CTCCTCGGCC TCGTCACGTG 
TTCAATATGC TAAAGAAGTA TGTCCGCGCA GAACAGAAGG ACAGACAGCA CACCCTAAAG 
CATTTCGAGC ATGTGCGCAT GGTGGATCCC AAGAAAGCCG CTCAGATCCG GTCCCAGGTT 
ATGACACACC TCCGTGTGAT TTATGAGCGC ATGAATCAGT CTCTCTCCCT GCTCTACAAC 
GTGCCTGCAG TGGCCGAGGA GATTCAGGAT GAAGTTGATG AGCTGCTTCA GAAAGAGCAA 
AACTATTCAG ATGACGTCTT GGCCAACATG ATTAGTGAAC CAAGGATCAG TTACGGAAAC 
GATGCTCTCA TGCCATCTTT GACCGAAACG AAAACCACCG TGGAGCTCCT TCCCGTGAAT 
GGAGAGTTCA GCCTGGACGA TCTCCAGCCG TGGCATTCTT TTGGGGCTGA CTCTGTGCCA 
GCCAACACAG AAAACGAAGT TGAGCCTGTT GATGCCCGCC CTGCTGCCGA CCGAGGACTG 
ACCACTCGAC CAGGTTCTGG GTTGACAAAT ATCAAGACGG AGGAGATCTC TGAAGTGAAG 
ATGGATGCAG AATTCCGACA TGACTCAGGA TATGAAGTTC ATCATCAAAA ATTGGTGTTC 
TTTGCAGAAG ATGTGGGTTC AAACAAAGGT GCAATCATTG GACTCATGGT GGGCGGTGTT 
GTCATAGCGA CAGTGATCGT CATCACCTTG GTGATGCTGA AGAAGAAACA GTACACATCC 
ATTCATCATG GTGTGGTGGA GGTTGACGCC GCTGTCACCC CAGAGGAGCG CCACCTGTCC 
AAGATGCAGC AGAACGGCTA CGAAAATCCA ACCTACAAGT TCTTTGAGCA GATGCAGAAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_000484.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000475.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27259
Clone ID Related Accession (Same CDS sequence)	NM_000484.3 , NM_000484.4
Accession Version	NM_000484.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2313bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	amyloid-beta A4 protein isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, AK312326.1, BC065529.1 and BM876312.1. This sequence is a reference standard in the RefSeqGene project. On Apr 29, 2009 this sequence version replaced NM_000484.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also known as PreA4 770). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.117485.1, SRR1803616.86136.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATGTCCCA AAGTTTACTC AAGACTACCC AGGAACCTCT TGCCCGAGAT 
CCTGTTAAAC TTCCTACAAC AGCAGCCAGT ACCCCTGATG CCGTTGACAA GTATCTCGAG 
ACACCTGGGG ATGAGAATGA ACATGCCCAT TTCCAGAAAG CCAAAGAGAG GCTTGAGGCC 
AAGCACCGAG AGAGAATGTC CCAGGTCATG AGAGAATGGG AAGAGGCAGA ACGTCAAGCA 
AAGAACTTGC CTAAAGCTGA TAAGAAGGCA GTTATCCAGC ATTTCCAGGA GAAAGTGGAA 
TCTTTGGAAC AGGAAGCAGC CAACGAGAGA CAGCAGCTGG TGGAGACACA CATGGCCAGA 
GTGGAAGCCA TGCTCAATGA CCGCCGCCGC CTGGCCCTGG AGAACTACAT CACCGCTCTG 
CAGGCTGTTC CTCCTCGGCC TCGTCACGTG TTCAATATGC TAAAGAAGTA TGTCCGCGCA 
GAACAGAAGG ACAGACAGCA CACCCTAAAG CATTTCGAGC ATGTGCGCAT GGTGGATCCC 
AAGAAAGCCG CTCAGATCCG GTCCCAGGTT ATGACACACC TCCGTGTGAT TTATGAGCGC 
ATGAATCAGT CTCTCTCCCT GCTCTACAAC GTGCCTGCAG TGGCCGAGGA GATTCAGGAT 
GAAGTTGATG AGCTGCTTCA GAAAGAGCAA AACTATTCAG ATGACGTCTT GGCCAACATG 
ATTAGTGAAC CAAGGATCAG TTACGGAAAC GATGCTCTCA TGCCATCTTT GACCGAAACG 
AAAACCACCG TGGAGCTCCT TCCCGTGAAT GGAGAGTTCA GCCTGGACGA TCTCCAGCCG 
TGGCATTCTT TTGGGGCTGA CTCTGTGCCA GCCAACACAG AAAACGAAGT TGAGCCTGTT 
GATGCCCGCC CTGCTGCCGA CCGAGGACTG ACCACTCGAC CAGGTTCTGG GTTGACAAAT 
ATCAAGACGG AGGAGATCTC TGAAGTGAAG ATGGATGCAG AATTCCGACA TGACTCAGGA 
TATGAAGTTC ATCATCAAAA ATTGGTGTTC TTTGCAGAAG ATGTGGGTTC AAACAAAGGT 
GCAATCATTG GACTCATGGT GGGCGGTGTT GTCATAGCGA CAGTGATCGT CATCACCTTG 
GTGATGCTGA AGAAGAAACA GTACACATCC ATTCATCATG GTGTGGTGGA GGTTGACGCC 
GCTGTCACCC CAGAGGAGCG CCACCTGTCC AAGATGCAGC AGAACGGCTA CGAAAATCCA 
ACCTACAAGT TCTTTGAGCA GATGCAGAAC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000475.1
CDS	201..2513
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_000484.3
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000484.3

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATGTCCCA AAGTTTACTC AAGACTACCC AGGAACCTCT TGCCCGAGAT 
CCTGTTAAAC TTCCTACAAC AGCAGCCAGT ACCCCTGATG CCGTTGACAA GTATCTCGAG 
ACACCTGGGG ATGAGAATGA ACATGCCCAT TTCCAGAAAG CCAAAGAGAG GCTTGAGGCC 
AAGCACCGAG AGAGAATGTC CCAGGTCATG AGAGAATGGG AAGAGGCAGA ACGTCAAGCA 
AAGAACTTGC CTAAAGCTGA TAAGAAGGCA GTTATCCAGC ATTTCCAGGA GAAAGTGGAA 
TCTTTGGAAC AGGAAGCAGC CAACGAGAGA CAGCAGCTGG TGGAGACACA CATGGCCAGA 
GTGGAAGCCA TGCTCAATGA CCGCCGCCGC CTGGCCCTGG AGAACTACAT CACCGCTCTG 
CAGGCTGTTC CTCCTCGGCC TCGTCACGTG TTCAATATGC TAAAGAAGTA TGTCCGCGCA 
GAACAGAAGG ACAGACAGCA CACCCTAAAG CATTTCGAGC ATGTGCGCAT GGTGGATCCC 
AAGAAAGCCG CTCAGATCCG GTCCCAGGTT ATGACACACC TCCGTGTGAT TTATGAGCGC 
ATGAATCAGT CTCTCTCCCT GCTCTACAAC GTGCCTGCAG TGGCCGAGGA GATTCAGGAT 
GAAGTTGATG AGCTGCTTCA GAAAGAGCAA AACTATTCAG ATGACGTCTT GGCCAACATG 
ATTAGTGAAC CAAGGATCAG TTACGGAAAC GATGCTCTCA TGCCATCTTT GACCGAAACG 
AAAACCACCG TGGAGCTCCT TCCCGTGAAT GGAGAGTTCA GCCTGGACGA TCTCCAGCCG 
TGGCATTCTT TTGGGGCTGA CTCTGTGCCA GCCAACACAG AAAACGAAGT TGAGCCTGTT 
GATGCCCGCC CTGCTGCCGA CCGAGGACTG ACCACTCGAC CAGGTTCTGG GTTGACAAAT 
ATCAAGACGG AGGAGATCTC TGAAGTGAAG ATGGATGCAG AATTCCGACA TGACTCAGGA 
TATGAAGTTC ATCATCAAAA ATTGGTGTTC TTTGCAGAAG ATGTGGGTTC AAACAAAGGT 
GCAATCATTG GACTCATGGT GGGCGGTGTT GTCATAGCGA CAGTGATCGT CATCACCTTG 
GTGATGCTGA AGAAGAAACA GTACACATCC ATTCATCATG GTGTGGTGGA GGTTGACGCC 
GCTGTCACCC CAGAGGAGCG CCACCTGTCC AAGATGCAGC AGAACGGCTA CGAAAATCCA 
ACCTACAAGT TCTTTGAGCA GATGCAGAAC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_000484.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000475.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27259
Clone ID Related Accession (Same CDS sequence)	NM_000484.3 , NM_000484.4
Accession Version	NM_000484.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2313bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, AK312326.1, BC065529.1 and BM876312.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_000484.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also known as PreA4 770). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.184771.1, SRR1660807.117485.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000346798.8/ ENSP00000284981.4 Protein has antimicrobial activity :: PMID: 20209079 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATGTCCCA AAGTTTACTC AAGACTACCC AGGAACCTCT TGCCCGAGAT 
CCTGTTAAAC TTCCTACAAC AGCAGCCAGT ACCCCTGATG CCGTTGACAA GTATCTCGAG 
ACACCTGGGG ATGAGAATGA ACATGCCCAT TTCCAGAAAG CCAAAGAGAG GCTTGAGGCC 
AAGCACCGAG AGAGAATGTC CCAGGTCATG AGAGAATGGG AAGAGGCAGA ACGTCAAGCA 
AAGAACTTGC CTAAAGCTGA TAAGAAGGCA GTTATCCAGC ATTTCCAGGA GAAAGTGGAA 
TCTTTGGAAC AGGAAGCAGC CAACGAGAGA CAGCAGCTGG TGGAGACACA CATGGCCAGA 
GTGGAAGCCA TGCTCAATGA CCGCCGCCGC CTGGCCCTGG AGAACTACAT CACCGCTCTG 
CAGGCTGTTC CTCCTCGGCC TCGTCACGTG TTCAATATGC TAAAGAAGTA TGTCCGCGCA 
GAACAGAAGG ACAGACAGCA CACCCTAAAG CATTTCGAGC ATGTGCGCAT GGTGGATCCC 
AAGAAAGCCG CTCAGATCCG GTCCCAGGTT ATGACACACC TCCGTGTGAT TTATGAGCGC 
ATGAATCAGT CTCTCTCCCT GCTCTACAAC GTGCCTGCAG TGGCCGAGGA GATTCAGGAT 
GAAGTTGATG AGCTGCTTCA GAAAGAGCAA AACTATTCAG ATGACGTCTT GGCCAACATG 
ATTAGTGAAC CAAGGATCAG TTACGGAAAC GATGCTCTCA TGCCATCTTT GACCGAAACG 
AAAACCACCG TGGAGCTCCT TCCCGTGAAT GGAGAGTTCA GCCTGGACGA TCTCCAGCCG 
TGGCATTCTT TTGGGGCTGA CTCTGTGCCA GCCAACACAG AAAACGAAGT TGAGCCTGTT 
GATGCCCGCC CTGCTGCCGA CCGAGGACTG ACCACTCGAC CAGGTTCTGG GTTGACAAAT 
ATCAAGACGG AGGAGATCTC TGAAGTGAAG ATGGATGCAG AATTCCGACA TGACTCAGGA 
TATGAAGTTC ATCATCAAAA ATTGGTGTTC TTTGCAGAAG ATGTGGGTTC AAACAAAGGT 
GCAATCATTG GACTCATGGT GGGCGGTGTT GTCATAGCGA CAGTGATCGT CATCACCTTG 
GTGATGCTGA AGAAGAAACA GTACACATCC ATTCATCATG GTGTGGTGGA GGTTGACGCC 
GCTGTCACCC CAGAGGAGCG CCACCTGTCC AAGATGCAGC AGAACGGCTA CGAAAATCCA 
ACCTACAAGT TCTTTGAGCA GATGCAGAAC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000475.1
CDS	151..2463
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_000484.4
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000484.4

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATGTCCCA AAGTTTACTC AAGACTACCC AGGAACCTCT TGCCCGAGAT 
CCTGTTAAAC TTCCTACAAC AGCAGCCAGT ACCCCTGATG CCGTTGACAA GTATCTCGAG 
ACACCTGGGG ATGAGAATGA ACATGCCCAT TTCCAGAAAG CCAAAGAGAG GCTTGAGGCC 
AAGCACCGAG AGAGAATGTC CCAGGTCATG AGAGAATGGG AAGAGGCAGA ACGTCAAGCA 
AAGAACTTGC CTAAAGCTGA TAAGAAGGCA GTTATCCAGC ATTTCCAGGA GAAAGTGGAA 
TCTTTGGAAC AGGAAGCAGC CAACGAGAGA CAGCAGCTGG TGGAGACACA CATGGCCAGA 
GTGGAAGCCA TGCTCAATGA CCGCCGCCGC CTGGCCCTGG AGAACTACAT CACCGCTCTG 
CAGGCTGTTC CTCCTCGGCC TCGTCACGTG TTCAATATGC TAAAGAAGTA TGTCCGCGCA 
GAACAGAAGG ACAGACAGCA CACCCTAAAG CATTTCGAGC ATGTGCGCAT GGTGGATCCC 
AAGAAAGCCG CTCAGATCCG GTCCCAGGTT ATGACACACC TCCGTGTGAT TTATGAGCGC 
ATGAATCAGT CTCTCTCCCT GCTCTACAAC GTGCCTGCAG TGGCCGAGGA GATTCAGGAT 
GAAGTTGATG AGCTGCTTCA GAAAGAGCAA AACTATTCAG ATGACGTCTT GGCCAACATG 
ATTAGTGAAC CAAGGATCAG TTACGGAAAC GATGCTCTCA TGCCATCTTT GACCGAAACG 
AAAACCACCG TGGAGCTCCT TCCCGTGAAT GGAGAGTTCA GCCTGGACGA TCTCCAGCCG 
TGGCATTCTT TTGGGGCTGA CTCTGTGCCA GCCAACACAG AAAACGAAGT TGAGCCTGTT 
GATGCCCGCC CTGCTGCCGA CCGAGGACTG ACCACTCGAC CAGGTTCTGG GTTGACAAAT 
ATCAAGACGG AGGAGATCTC TGAAGTGAAG ATGGATGCAG AATTCCGACA TGACTCAGGA 
TATGAAGTTC ATCATCAAAA ATTGGTGTTC TTTGCAGAAG ATGTGGGTTC AAACAAAGGT 
GCAATCATTG GACTCATGGT GGGCGGTGTT GTCATAGCGA CAGTGATCGT CATCACCTTG 
GTGATGCTGA AGAAGAAACA GTACACATCC ATTCATCATG GTGTGGTGGA GGTTGACGCC 
GCTGTCACCC CAGAGGAGCG CCACCTGTCC AAGATGCAGC AGAACGGCTA CGAAAATCCA 
ACCTACAAGT TCTTTGAGCA GATGCAGAAC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_001136016.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129488.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu27130
Clone ID Related Accession (Same CDS sequence)	NM_001136016.3
Accession Version	NM_001136016.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2241bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK311717.1, AK295621.1, Y00264.1 and BM876312.1. On Feb 24, 2011 this sequence version replaced NM_001136016.2. Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (d) has a shorter and distinct N-terminus and lacks an internal segment compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK295621.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACCAAT TAGAGGACTT GTTGGTTCTG TTTATCAACT ATGTACCCAC TGATGGTAAT 
GCTGGCCTGC TGGCTGAACC CCAGATTGCC ATGTTCTGTG GCAGACTGAA CATGCACATG 
AATGTCCAGA ATGGGAAGTG GGATTCAGAT CCATCAGGGA CCAAAACCTG CATTGATACC 
AAGGAAGGCA TCCTGCAGTA TTGCCAAGAA GTCTACCCTG AACTGCAGAT CACCAATGTG 
GTAGAAGCCA ACCAACCAGT GACCATCCAG AACTGGTGCA AGCGGGGCCG CAAGCAGTGC 
AAGACCCATC CCCACTTTGT GATTCCCTAC CGCTGCTTAG TTGGTGAGTT TGTAAGTGAT 
GCCCTTCTCG TTCCTGACAA GTGCAAATTC TTACACCAGG AGAGGATGGA TGTTTGCGAA 
ACTCATCTTC ACTGGCACAC CGTCGCCAAA GAGACATGCA GTGAGAAGAG TACCAACTTG 
CATGACTACG GCATGTTGCT GCCCTGCGGA ATTGACAAGT TCCGAGGGGT AGAGTTTGTG 
TGTTGCCCAC TGGCTGAAGA AAGTGACAAT GTGGATTCTG CTGATGCGGA GGAGGATGAC 
TCGGATGTCT GGTGGGGCGG AGCAGACACA GACTATGCAG ATGGGAGTGA AGACAAAGTA 
GTAGAAGTAG CAGAGGAGGA AGAAGTGGCT GAGGTGGAAG AAGAAGAAGC CGATGATGAC 
GAGGACGATG AGGATGGTGA TGAGGTAGAG GAAGAGGCTG AGGAACCCTA CGAAGAAGCC 
ACAGAGAGAA CCACCAGCAT TGCCACCACC ACCACCACCA CCACAGAGTC TGTGGAAGAG 
GTGGTTCGAG AGGTGTGCTC TGAACAAGCC GAGACGGGGC CGTGCCGAGC AATGATCTCC 
CGCTGGTACT TTGATGTGAC TGAAGGGAAG TGTGCCCCAT TCTTTTACGG CGGATGTGGC 
GGCAACCGGA ACAACTTTGA CACAGAAGAG TACTGCATGG CCGTGTGTGG CAGCGCCATT 
CCTACAACAG CAGCCAGTAC CCCTGATGCC GTTGACAAGT ATCTCGAGAC ACCTGGGGAT 
GAGAATGAAC ATGCCCATTT CCAGAAAGCC AAAGAGAGGC TTGAGGCCAA GCACCGAGAG 
AGAATGTCCC AGGTCATGAG AGAATGGGAA GAGGCAGAAC GTCAAGCAAA GAACTTGCCT 
AAAGCTGATA AGAAGGCAGT TATCCAGCAT TTCCAGGAGA AAGTGGAATC TTTGGAACAG 
GAAGCAGCCA ACGAGAGACA GCAGCTGGTG GAGACACACA TGGCCAGAGT GGAAGCCATG 
CTCAATGACC GCCGCCGCCT GGCCCTGGAG AACTACATCA CCGCTCTGCA GGCTGTTCCT 
CCTCGGCCTC GTCACGTGTT CAATATGCTA AAGAAGTATG TCCGCGCAGA ACAGAAGGAC 
AGACAGCACA CCCTAAAGCA TTTCGAGCAT GTGCGCATGG TGGATCCCAA GAAAGCCGCT 
CAGATCCGGT CCCAGGTTAT GACACACCTC CGTGTGATTT ATGAGCGCAT GAATCAGTCT 
CTCTCCCTGC TCTACAACGT GCCTGCAGTG GCCGAGGAGA TTCAGGATGA AGTTGATGAG 
CTGCTTCAGA AAGAGCAAAA CTATTCAGAT GACGTCTTGG CCAACATGAT TAGTGAACCA 
AGGATCAGTT ACGGAAACGA TGCTCTCATG CCATCTTTGA CCGAAACGAA AACCACCGTG 
GAGCTCCTTC CCGTGAATGG AGAGTTCAGC CTGGACGATC TCCAGCCGTG GCATTCTTTT 
GGGGCTGACT CTGTGCCAGC CAACACAGAA AACGAAGTTG AGCCTGTTGA TGCCCGCCCT 
GCTGCCGACC GAGGACTGAC CACTCGACCA GGTTCTGGGT TGACAAATAT CAAGACGGAG 
GAGATCTCTG AAGTGAAGAT GGATGCAGAA TTCCGACATG ACTCAGGATA TGAAGTTCAT 
CATCAAAAAT TGGTGTTCTT TGCAGAAGAT GTGGGTTCAA ACAAAGGTGC AATCATTGGA 
CTCATGGTGG GCGGTGTTGT CATAGCGACA GTGATCGTCA TCACCTTGGT GATGCTGAAG 
AAGAAACAGT ACACATCCAT TCATCATGGT GTGGTGGAGG TTGACGCCGC TGTCACCCCA 
GAGGAGCGCC ACCTGTCCAA GATGCAGCAG AACGGCTACG AAAATCCAAC CTACAAGTTC 
TTTGAGCAGA TGCAGAACTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129488.1
CDS	197..2437
Translation	MDQLEDLLVLFINYVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_001136016.3
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001136016.3

ORF Insert Sequence:

ATGGACCAAT TAGAGGACTT GTTGGTTCTG TTTATCAACT ATGTACCCAC TGATGGTAAT 
GCTGGCCTGC TGGCTGAACC CCAGATTGCC ATGTTCTGTG GCAGACTGAA CATGCACATG 
AATGTCCAGA ATGGGAAGTG GGATTCAGAT CCATCAGGGA CCAAAACCTG CATTGATACC 
AAGGAAGGCA TCCTGCAGTA TTGCCAAGAA GTCTACCCTG AACTGCAGAT CACCAATGTG 
GTAGAAGCCA ACCAACCAGT GACCATCCAG AACTGGTGCA AGCGGGGCCG CAAGCAGTGC 
AAGACCCATC CCCACTTTGT GATTCCCTAC CGCTGCTTAG TTGGTGAGTT TGTAAGTGAT 
GCCCTTCTCG TTCCTGACAA GTGCAAATTC TTACACCAGG AGAGGATGGA TGTTTGCGAA 
ACTCATCTTC ACTGGCACAC CGTCGCCAAA GAGACATGCA GTGAGAAGAG TACCAACTTG 
CATGACTACG GCATGTTGCT GCCCTGCGGA ATTGACAAGT TCCGAGGGGT AGAGTTTGTG 
TGTTGCCCAC TGGCTGAAGA AAGTGACAAT GTGGATTCTG CTGATGCGGA GGAGGATGAC 
TCGGATGTCT GGTGGGGCGG AGCAGACACA GACTATGCAG ATGGGAGTGA AGACAAAGTA 
GTAGAAGTAG CAGAGGAGGA AGAAGTGGCT GAGGTGGAAG AAGAAGAAGC CGATGATGAC 
GAGGACGATG AGGATGGTGA TGAGGTAGAG GAAGAGGCTG AGGAACCCTA CGAAGAAGCC 
ACAGAGAGAA CCACCAGCAT TGCCACCACC ACCACCACCA CCACAGAGTC TGTGGAAGAG 
GTGGTTCGAG AGGTGTGCTC TGAACAAGCC GAGACGGGGC CGTGCCGAGC AATGATCTCC 
CGCTGGTACT TTGATGTGAC TGAAGGGAAG TGTGCCCCAT TCTTTTACGG CGGATGTGGC 
GGCAACCGGA ACAACTTTGA CACAGAAGAG TACTGCATGG CCGTGTGTGG CAGCGCCATT 
CCTACAACAG CAGCCAGTAC CCCTGATGCC GTTGACAAGT ATCTCGAGAC ACCTGGGGAT 
GAGAATGAAC ATGCCCATTT CCAGAAAGCC AAAGAGAGGC TTGAGGCCAA GCACCGAGAG 
AGAATGTCCC AGGTCATGAG AGAATGGGAA GAGGCAGAAC GTCAAGCAAA GAACTTGCCT 
AAAGCTGATA AGAAGGCAGT TATCCAGCAT TTCCAGGAGA AAGTGGAATC TTTGGAACAG 
GAAGCAGCCA ACGAGAGACA GCAGCTGGTG GAGACACACA TGGCCAGAGT GGAAGCCATG 
CTCAATGACC GCCGCCGCCT GGCCCTGGAG AACTACATCA CCGCTCTGCA GGCTGTTCCT 
CCTCGGCCTC GTCACGTGTT CAATATGCTA AAGAAGTATG TCCGCGCAGA ACAGAAGGAC 
AGACAGCACA CCCTAAAGCA TTTCGAGCAT GTGCGCATGG TGGATCCCAA GAAAGCCGCT 
CAGATCCGGT CCCAGGTTAT GACACACCTC CGTGTGATTT ATGAGCGCAT GAATCAGTCT 
CTCTCCCTGC TCTACAACGT GCCTGCAGTG GCCGAGGAGA TTCAGGATGA AGTTGATGAG 
CTGCTTCAGA AAGAGCAAAA CTATTCAGAT GACGTCTTGG CCAACATGAT TAGTGAACCA 
AGGATCAGTT ACGGAAACGA TGCTCTCATG CCATCTTTGA CCGAAACGAA AACCACCGTG 
GAGCTCCTTC CCGTGAATGG AGAGTTCAGC CTGGACGATC TCCAGCCGTG GCATTCTTTT 
GGGGCTGACT CTGTGCCAGC CAACACAGAA AACGAAGTTG AGCCTGTTGA TGCCCGCCCT 
GCTGCCGACC GAGGACTGAC CACTCGACCA GGTTCTGGGT TGACAAATAT CAAGACGGAG 
GAGATCTCTG AAGTGAAGAT GGATGCAGAA TTCCGACATG ACTCAGGATA TGAAGTTCAT 
CATCAAAAAT TGGTGTTCTT TGCAGAAGAT GTGGGTTCAA ACAAAGGTGC AATCATTGGA 
CTCATGGTGG GCGGTGTTGT CATAGCGACA GTGATCGTCA TCACCTTGGT GATGCTGAAG 
AAGAAACAGT ACACATCCAT TCATCATGGT GTGGTGGAGG TTGACGCCGC TGTCACCCCA 
GAGGAGCGCC ACCTGTCCAA GATGCAGCAG AACGGCTACG AAAATCCAAC CTACAAGTTC 
TTTGAGCAGA TGCAGAACTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_001204302.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191231.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 9, mRNA.

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CloneID	OHu27201
Clone ID Related Accession (Same CDS sequence)	NM_001204302.1 , NM_001204302.2
Accession Version	NM_001204302.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2202bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform i precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, X06989.1, Y00264.1 and BM876312.1. Transcript Variant: This variant (9) lacks two alternate in-frame exons compared to variant 1. The resulting isoform (i, also known as L-APP733) has the same N- and C-termini but is shorter compared to isoform a. No full-length transcript is available for this transcript; however, it is supported by PMID:1429732 and other publications. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.217803.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATTCCTAC AACAGCAGCC AGTACCCCTG ATGCCGTTGA CAAGTATCTC 
GAGACACCTG GGGATGAGAA TGAACATGCC CATTTCCAGA AAGCCAAAGA GAGGCTTGAG 
GCCAAGCACC GAGAGAGAAT GTCCCAGGTC ATGAGAGAAT GGGAAGAGGC AGAACGTCAA 
GCAAAGAACT TGCCTAAAGC TGATAAGAAG GCAGTTATCC AGCATTTCCA GGAGAAAGTG 
GAATCTTTGG AACAGGAAGC AGCCAACGAG AGACAGCAGC TGGTGGAGAC ACACATGGCC 
AGAGTGGAAG CCATGCTCAA TGACCGCCGC CGCCTGGCCC TGGAGAACTA CATCACCGCT 
CTGCAGGCTG TTCCTCCTCG GCCTCGTCAC GTGTTCAATA TGCTAAAGAA GTATGTCCGC 
GCAGAACAGA AGGACAGACA GCACACCCTA AAGCATTTCG AGCATGTGCG CATGGTGGAT 
CCCAAGAAAG CCGCTCAGAT CCGGTCCCAG GTTATGACAC ACCTCCGTGT GATTTATGAG 
CGCATGAATC AGTCTCTCTC CCTGCTCTAC AACGTGCCTG CAGTGGCCGA GGAGATTCAG 
GATGAAGTTG ATGAGCTGCT TCAGAAAGAG CAAAACTATT CAGATGACGT CTTGGCCAAC 
ATGATTAGTG AACCAAGGAT CAGTTACGGA AACGATGCTC TCATGCCATC TTTGACCGAA 
ACGAAAACCA CCGTGGAGCT CCTTCCCGTG AATGGAGAGT TCAGCCTGGA CGATCTCCAG 
CCGTGGCATT CTTTTGGGGC TGACTCTGTG CCAGCCAACA CAGAAAACGA AGGTTCTGGG 
TTGACAAATA TCAAGACGGA GGAGATCTCT GAAGTGAAGA TGGATGCAGA ATTCCGACAT 
GACTCAGGAT ATGAAGTTCA TCATCAAAAA TTGGTGTTCT TTGCAGAAGA TGTGGGTTCA 
AACAAAGGTG CAATCATTGG ACTCATGGTG GGCGGTGTTG TCATAGCGAC AGTGATCGTC 
ATCACCTTGG TGATGCTGAA GAAGAAACAG TACACATCCA TTCATCATGG TGTGGTGGAG 
GTTGACGCCG CTGTCACCCC AGAGGAGCGC CACCTGTCCA AGATGCAGCA GAACGGCTAC 
GAAAATCCAA CCTACAAGTT CTTTGAGCAG ATGCAGAACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191231.1
CDS	201..2402
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_001204302.1
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204302.1

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATTCCTAC AACAGCAGCC AGTACCCCTG ATGCCGTTGA CAAGTATCTC 
GAGACACCTG GGGATGAGAA TGAACATGCC CATTTCCAGA AAGCCAAAGA GAGGCTTGAG 
GCCAAGCACC GAGAGAGAAT GTCCCAGGTC ATGAGAGAAT GGGAAGAGGC AGAACGTCAA 
GCAAAGAACT TGCCTAAAGC TGATAAGAAG GCAGTTATCC AGCATTTCCA GGAGAAAGTG 
GAATCTTTGG AACAGGAAGC AGCCAACGAG AGACAGCAGC TGGTGGAGAC ACACATGGCC 
AGAGTGGAAG CCATGCTCAA TGACCGCCGC CGCCTGGCCC TGGAGAACTA CATCACCGCT 
CTGCAGGCTG TTCCTCCTCG GCCTCGTCAC GTGTTCAATA TGCTAAAGAA GTATGTCCGC 
GCAGAACAGA AGGACAGACA GCACACCCTA AAGCATTTCG AGCATGTGCG CATGGTGGAT 
CCCAAGAAAG CCGCTCAGAT CCGGTCCCAG GTTATGACAC ACCTCCGTGT GATTTATGAG 
CGCATGAATC AGTCTCTCTC CCTGCTCTAC AACGTGCCTG CAGTGGCCGA GGAGATTCAG 
GATGAAGTTG ATGAGCTGCT TCAGAAAGAG CAAAACTATT CAGATGACGT CTTGGCCAAC 
ATGATTAGTG AACCAAGGAT CAGTTACGGA AACGATGCTC TCATGCCATC TTTGACCGAA 
ACGAAAACCA CCGTGGAGCT CCTTCCCGTG AATGGAGAGT TCAGCCTGGA CGATCTCCAG 
CCGTGGCATT CTTTTGGGGC TGACTCTGTG CCAGCCAACA CAGAAAACGA AGGTTCTGGG 
TTGACAAATA TCAAGACGGA GGAGATCTCT GAAGTGAAGA TGGATGCAGA ATTCCGACAT 
GACTCAGGAT ATGAAGTTCA TCATCAAAAA TTGGTGTTCT TTGCAGAAGA TGTGGGTTCA 
AACAAAGGTG CAATCATTGG ACTCATGGTG GGCGGTGTTG TCATAGCGAC AGTGATCGTC 
ATCACCTTGG TGATGCTGAA GAAGAAACAG TACACATCCA TTCATCATGG TGTGGTGGAG 
GTTGACGCCG CTGTCACCCC AGAGGAGCGC CACCTGTCCA AGATGCAGCA GAACGGCTAC 
GAAAATCCAA CCTACAAGTT CTTTGAGCAG ATGCAGAACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_001204302.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191231.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 9, mRNA.

Price & Availability↑

CloneID	OHu27201
Clone ID Related Accession (Same CDS sequence)	NM_001204302.1 , NM_001204302.2
Accession Version	NM_001204302.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2202bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform i precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, X06989.1, Y00264.1 and BM876312.1. On May 31, 2019 this sequence version replaced NM_001204302.1. Transcript Variant: This variant (9) lacks two alternate in-frame exons compared to variant 1. The resulting isoform (i, also known as L-APP733) has the same N- and C-termini but is shorter compared to isoform a. No full-length transcript is available for this transcript; however, it is supported by PMID:1429732 and other publications. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.217803.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATTCCTAC AACAGCAGCC AGTACCCCTG ATGCCGTTGA CAAGTATCTC 
GAGACACCTG GGGATGAGAA TGAACATGCC CATTTCCAGA AAGCCAAAGA GAGGCTTGAG 
GCCAAGCACC GAGAGAGAAT GTCCCAGGTC ATGAGAGAAT GGGAAGAGGC AGAACGTCAA 
GCAAAGAACT TGCCTAAAGC TGATAAGAAG GCAGTTATCC AGCATTTCCA GGAGAAAGTG 
GAATCTTTGG AACAGGAAGC AGCCAACGAG AGACAGCAGC TGGTGGAGAC ACACATGGCC 
AGAGTGGAAG CCATGCTCAA TGACCGCCGC CGCCTGGCCC TGGAGAACTA CATCACCGCT 
CTGCAGGCTG TTCCTCCTCG GCCTCGTCAC GTGTTCAATA TGCTAAAGAA GTATGTCCGC 
GCAGAACAGA AGGACAGACA GCACACCCTA AAGCATTTCG AGCATGTGCG CATGGTGGAT 
CCCAAGAAAG CCGCTCAGAT CCGGTCCCAG GTTATGACAC ACCTCCGTGT GATTTATGAG 
CGCATGAATC AGTCTCTCTC CCTGCTCTAC AACGTGCCTG CAGTGGCCGA GGAGATTCAG 
GATGAAGTTG ATGAGCTGCT TCAGAAAGAG CAAAACTATT CAGATGACGT CTTGGCCAAC 
ATGATTAGTG AACCAAGGAT CAGTTACGGA AACGATGCTC TCATGCCATC TTTGACCGAA 
ACGAAAACCA CCGTGGAGCT CCTTCCCGTG AATGGAGAGT TCAGCCTGGA CGATCTCCAG 
CCGTGGCATT CTTTTGGGGC TGACTCTGTG CCAGCCAACA CAGAAAACGA AGGTTCTGGG 
TTGACAAATA TCAAGACGGA GGAGATCTCT GAAGTGAAGA TGGATGCAGA ATTCCGACAT 
GACTCAGGAT ATGAAGTTCA TCATCAAAAA TTGGTGTTCT TTGCAGAAGA TGTGGGTTCA 
AACAAAGGTG CAATCATTGG ACTCATGGTG GGCGGTGTTG TCATAGCGAC AGTGATCGTC 
ATCACCTTGG TGATGCTGAA GAAGAAACAG TACACATCCA TTCATCATGG TGTGGTGGAG 
GTTGACGCCG CTGTCACCCC AGAGGAGCGC CACCTGTCCA AGATGCAGCA GAACGGCTAC 
GAAAATCCAA CCTACAAGTT CTTTGAGCAG ATGCAGAACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191231.1
CDS	151..2352
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_001204302.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204302.2

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATTCCTAC AACAGCAGCC AGTACCCCTG ATGCCGTTGA CAAGTATCTC 
GAGACACCTG GGGATGAGAA TGAACATGCC CATTTCCAGA AAGCCAAAGA GAGGCTTGAG 
GCCAAGCACC GAGAGAGAAT GTCCCAGGTC ATGAGAGAAT GGGAAGAGGC AGAACGTCAA 
GCAAAGAACT TGCCTAAAGC TGATAAGAAG GCAGTTATCC AGCATTTCCA GGAGAAAGTG 
GAATCTTTGG AACAGGAAGC AGCCAACGAG AGACAGCAGC TGGTGGAGAC ACACATGGCC 
AGAGTGGAAG CCATGCTCAA TGACCGCCGC CGCCTGGCCC TGGAGAACTA CATCACCGCT 
CTGCAGGCTG TTCCTCCTCG GCCTCGTCAC GTGTTCAATA TGCTAAAGAA GTATGTCCGC 
GCAGAACAGA AGGACAGACA GCACACCCTA AAGCATTTCG AGCATGTGCG CATGGTGGAT 
CCCAAGAAAG CCGCTCAGAT CCGGTCCCAG GTTATGACAC ACCTCCGTGT GATTTATGAG 
CGCATGAATC AGTCTCTCTC CCTGCTCTAC AACGTGCCTG CAGTGGCCGA GGAGATTCAG 
GATGAAGTTG ATGAGCTGCT TCAGAAAGAG CAAAACTATT CAGATGACGT CTTGGCCAAC 
ATGATTAGTG AACCAAGGAT CAGTTACGGA AACGATGCTC TCATGCCATC TTTGACCGAA 
ACGAAAACCA CCGTGGAGCT CCTTCCCGTG AATGGAGAGT TCAGCCTGGA CGATCTCCAG 
CCGTGGCATT CTTTTGGGGC TGACTCTGTG CCAGCCAACA CAGAAAACGA AGGTTCTGGG 
TTGACAAATA TCAAGACGGA GGAGATCTCT GAAGTGAAGA TGGATGCAGA ATTCCGACAT 
GACTCAGGAT ATGAAGTTCA TCATCAAAAA TTGGTGTTCT TTGCAGAAGA TGTGGGTTCA 
AACAAAGGTG CAATCATTGG ACTCATGGTG GGCGGTGTTG TCATAGCGAC AGTGATCGTC 
ATCACCTTGG TGATGCTGAA GAAGAAACAG TACACATCCA TTCATCATGG TGTGGTGGAG 
GTTGACGCCG CTGTCACCCC AGAGGAGCGC CACCTGTCCA AGATGCAGCA GAACGGCTAC 
GAAAATCCAA CCTACAAGTT CTTTGAGCAG ATGCAGAACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_001204301.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191230.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 8, mRNA.

Price & Availability↑

CloneID	OHu27229
Clone ID Related Accession (Same CDS sequence)	NM_001204301.1 , NM_001204301.2
Accession Version	NM_001204301.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2259bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform h precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, AK294534.1, AK312326.1, Y00264.1 and BM876312.1. Transcript Variant: This variant (8) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (h, also known as L-APP752) has the same N- and C-termini but is shorter compared to isoform a. No full-length transcript is available for this transcript; however, it is supported by PMID:1429732 and other publications. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.186377.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATGTCCCA AAGTTTACTC AAGACTACCC AGGAACCTCT TGCCCGAGAT 
CCTGTTAAAC TTCCTACAAC AGCAGCCAGT ACCCCTGATG CCGTTGACAA GTATCTCGAG 
ACACCTGGGG ATGAGAATGA ACATGCCCAT TTCCAGAAAG CCAAAGAGAG GCTTGAGGCC 
AAGCACCGAG AGAGAATGTC CCAGGTCATG AGAGAATGGG AAGAGGCAGA ACGTCAAGCA 
AAGAACTTGC CTAAAGCTGA TAAGAAGGCA GTTATCCAGC ATTTCCAGGA GAAAGTGGAA 
TCTTTGGAAC AGGAAGCAGC CAACGAGAGA CAGCAGCTGG TGGAGACACA CATGGCCAGA 
GTGGAAGCCA TGCTCAATGA CCGCCGCCGC CTGGCCCTGG AGAACTACAT CACCGCTCTG 
CAGGCTGTTC CTCCTCGGCC TCGTCACGTG TTCAATATGC TAAAGAAGTA TGTCCGCGCA 
GAACAGAAGG ACAGACAGCA CACCCTAAAG CATTTCGAGC ATGTGCGCAT GGTGGATCCC 
AAGAAAGCCG CTCAGATCCG GTCCCAGGTT ATGACACACC TCCGTGTGAT TTATGAGCGC 
ATGAATCAGT CTCTCTCCCT GCTCTACAAC GTGCCTGCAG TGGCCGAGGA GATTCAGGAT 
GAAGTTGATG AGCTGCTTCA GAAAGAGCAA AACTATTCAG ATGACGTCTT GGCCAACATG 
ATTAGTGAAC CAAGGATCAG TTACGGAAAC GATGCTCTCA TGCCATCTTT GACCGAAACG 
AAAACCACCG TGGAGCTCCT TCCCGTGAAT GGAGAGTTCA GCCTGGACGA TCTCCAGCCG 
TGGCATTCTT TTGGGGCTGA CTCTGTGCCA GCCAACACAG AAAACGAAGG TTCTGGGTTG 
ACAAATATCA AGACGGAGGA GATCTCTGAA GTGAAGATGG ATGCAGAATT CCGACATGAC 
TCAGGATATG AAGTTCATCA TCAAAAATTG GTGTTCTTTG CAGAAGATGT GGGTTCAAAC 
AAAGGTGCAA TCATTGGACT CATGGTGGGC GGTGTTGTCA TAGCGACAGT GATCGTCATC 
ACCTTGGTGA TGCTGAAGAA GAAACAGTAC ACATCCATTC ATCATGGTGT GGTGGAGGTT 
GACGCCGCTG TCACCCCAGA GGAGCGCCAC CTGTCCAAGA TGCAGCAGAA CGGCTACGAA 
AATCCAACCT ACAAGTTCTT TGAGCAGATG CAGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191230.1
CDS	201..2459
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_001204301.1
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204301.1

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATGTCCCA AAGTTTACTC AAGACTACCC AGGAACCTCT TGCCCGAGAT 
CCTGTTAAAC TTCCTACAAC AGCAGCCAGT ACCCCTGATG CCGTTGACAA GTATCTCGAG 
ACACCTGGGG ATGAGAATGA ACATGCCCAT TTCCAGAAAG CCAAAGAGAG GCTTGAGGCC 
AAGCACCGAG AGAGAATGTC CCAGGTCATG AGAGAATGGG AAGAGGCAGA ACGTCAAGCA 
AAGAACTTGC CTAAAGCTGA TAAGAAGGCA GTTATCCAGC ATTTCCAGGA GAAAGTGGAA 
TCTTTGGAAC AGGAAGCAGC CAACGAGAGA CAGCAGCTGG TGGAGACACA CATGGCCAGA 
GTGGAAGCCA TGCTCAATGA CCGCCGCCGC CTGGCCCTGG AGAACTACAT CACCGCTCTG 
CAGGCTGTTC CTCCTCGGCC TCGTCACGTG TTCAATATGC TAAAGAAGTA TGTCCGCGCA 
GAACAGAAGG ACAGACAGCA CACCCTAAAG CATTTCGAGC ATGTGCGCAT GGTGGATCCC 
AAGAAAGCCG CTCAGATCCG GTCCCAGGTT ATGACACACC TCCGTGTGAT TTATGAGCGC 
ATGAATCAGT CTCTCTCCCT GCTCTACAAC GTGCCTGCAG TGGCCGAGGA GATTCAGGAT 
GAAGTTGATG AGCTGCTTCA GAAAGAGCAA AACTATTCAG ATGACGTCTT GGCCAACATG 
ATTAGTGAAC CAAGGATCAG TTACGGAAAC GATGCTCTCA TGCCATCTTT GACCGAAACG 
AAAACCACCG TGGAGCTCCT TCCCGTGAAT GGAGAGTTCA GCCTGGACGA TCTCCAGCCG 
TGGCATTCTT TTGGGGCTGA CTCTGTGCCA GCCAACACAG AAAACGAAGG TTCTGGGTTG 
ACAAATATCA AGACGGAGGA GATCTCTGAA GTGAAGATGG ATGCAGAATT CCGACATGAC 
TCAGGATATG AAGTTCATCA TCAAAAATTG GTGTTCTTTG CAGAAGATGT GGGTTCAAAC 
AAAGGTGCAA TCATTGGACT CATGGTGGGC GGTGTTGTCA TAGCGACAGT GATCGTCATC 
ACCTTGGTGA TGCTGAAGAA GAAACAGTAC ACATCCATTC ATCATGGTGT GGTGGAGGTT 
GACGCCGCTG TCACCCCAGA GGAGCGCCAC CTGTCCAAGA TGCAGCAGAA CGGCTACGAA 
AATCCAACCT ACAAGTTCTT TGAGCAGATG CAGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_001204301.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191230.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 8, mRNA.

Price & Availability↑

CloneID	OHu27229
Clone ID Related Accession (Same CDS sequence)	NM_001204301.1 , NM_001204301.2
Accession Version	NM_001204301.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2259bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform h precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, AK294534.1, AK312326.1, Y00264.1 and BM876312.1. On May 31, 2019 this sequence version replaced NM_001204301.1. Transcript Variant: This variant (8) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (h, also known as L-APP752) has the same N- and C-termini but is shorter compared to isoform a. No full-length transcript is available for this transcript; however, it is supported by PMID:1429732 and other publications. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.186377.1, DRR138524.1300487.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATGTCCCA AAGTTTACTC AAGACTACCC AGGAACCTCT TGCCCGAGAT 
CCTGTTAAAC TTCCTACAAC AGCAGCCAGT ACCCCTGATG CCGTTGACAA GTATCTCGAG 
ACACCTGGGG ATGAGAATGA ACATGCCCAT TTCCAGAAAG CCAAAGAGAG GCTTGAGGCC 
AAGCACCGAG AGAGAATGTC CCAGGTCATG AGAGAATGGG AAGAGGCAGA ACGTCAAGCA 
AAGAACTTGC CTAAAGCTGA TAAGAAGGCA GTTATCCAGC ATTTCCAGGA GAAAGTGGAA 
TCTTTGGAAC AGGAAGCAGC CAACGAGAGA CAGCAGCTGG TGGAGACACA CATGGCCAGA 
GTGGAAGCCA TGCTCAATGA CCGCCGCCGC CTGGCCCTGG AGAACTACAT CACCGCTCTG 
CAGGCTGTTC CTCCTCGGCC TCGTCACGTG TTCAATATGC TAAAGAAGTA TGTCCGCGCA 
GAACAGAAGG ACAGACAGCA CACCCTAAAG CATTTCGAGC ATGTGCGCAT GGTGGATCCC 
AAGAAAGCCG CTCAGATCCG GTCCCAGGTT ATGACACACC TCCGTGTGAT TTATGAGCGC 
ATGAATCAGT CTCTCTCCCT GCTCTACAAC GTGCCTGCAG TGGCCGAGGA GATTCAGGAT 
GAAGTTGATG AGCTGCTTCA GAAAGAGCAA AACTATTCAG ATGACGTCTT GGCCAACATG 
ATTAGTGAAC CAAGGATCAG TTACGGAAAC GATGCTCTCA TGCCATCTTT GACCGAAACG 
AAAACCACCG TGGAGCTCCT TCCCGTGAAT GGAGAGTTCA GCCTGGACGA TCTCCAGCCG 
TGGCATTCTT TTGGGGCTGA CTCTGTGCCA GCCAACACAG AAAACGAAGG TTCTGGGTTG 
ACAAATATCA AGACGGAGGA GATCTCTGAA GTGAAGATGG ATGCAGAATT CCGACATGAC 
TCAGGATATG AAGTTCATCA TCAAAAATTG GTGTTCTTTG CAGAAGATGT GGGTTCAAAC 
AAAGGTGCAA TCATTGGACT CATGGTGGGC GGTGTTGTCA TAGCGACAGT GATCGTCATC 
ACCTTGGTGA TGCTGAAGAA GAAACAGTAC ACATCCATTC ATCATGGTGT GGTGGAGGTT 
GACGCCGCTG TCACCCCAGA GGAGCGCCAC CTGTCCAAGA TGCAGCAGAA CGGCTACGAA 
AATCCAACCT ACAAGTTCTT TGAGCAGATG CAGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191230.1
CDS	151..2409
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_001204301.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204301.2

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATGTCCCA AAGTTTACTC AAGACTACCC AGGAACCTCT TGCCCGAGAT 
CCTGTTAAAC TTCCTACAAC AGCAGCCAGT ACCCCTGATG CCGTTGACAA GTATCTCGAG 
ACACCTGGGG ATGAGAATGA ACATGCCCAT TTCCAGAAAG CCAAAGAGAG GCTTGAGGCC 
AAGCACCGAG AGAGAATGTC CCAGGTCATG AGAGAATGGG AAGAGGCAGA ACGTCAAGCA 
AAGAACTTGC CTAAAGCTGA TAAGAAGGCA GTTATCCAGC ATTTCCAGGA GAAAGTGGAA 
TCTTTGGAAC AGGAAGCAGC CAACGAGAGA CAGCAGCTGG TGGAGACACA CATGGCCAGA 
GTGGAAGCCA TGCTCAATGA CCGCCGCCGC CTGGCCCTGG AGAACTACAT CACCGCTCTG 
CAGGCTGTTC CTCCTCGGCC TCGTCACGTG TTCAATATGC TAAAGAAGTA TGTCCGCGCA 
GAACAGAAGG ACAGACAGCA CACCCTAAAG CATTTCGAGC ATGTGCGCAT GGTGGATCCC 
AAGAAAGCCG CTCAGATCCG GTCCCAGGTT ATGACACACC TCCGTGTGAT TTATGAGCGC 
ATGAATCAGT CTCTCTCCCT GCTCTACAAC GTGCCTGCAG TGGCCGAGGA GATTCAGGAT 
GAAGTTGATG AGCTGCTTCA GAAAGAGCAA AACTATTCAG ATGACGTCTT GGCCAACATG 
ATTAGTGAAC CAAGGATCAG TTACGGAAAC GATGCTCTCA TGCCATCTTT GACCGAAACG 
AAAACCACCG TGGAGCTCCT TCCCGTGAAT GGAGAGTTCA GCCTGGACGA TCTCCAGCCG 
TGGCATTCTT TTGGGGCTGA CTCTGTGCCA GCCAACACAG AAAACGAAGG TTCTGGGTTG 
ACAAATATCA AGACGGAGGA GATCTCTGAA GTGAAGATGG ATGCAGAATT CCGACATGAC 
TCAGGATATG AAGTTCATCA TCAAAAATTG GTGTTCTTTG CAGAAGATGT GGGTTCAAAC 
AAAGGTGCAA TCATTGGACT CATGGTGGGC GGTGTTGTCA TAGCGACAGT GATCGTCATC 
ACCTTGGTGA TGCTGAAGAA GAAACAGTAC ACATCCATTC ATCATGGTGT GGTGGAGGTT 
GACGCCGCTG TCACCCCAGA GGAGCGCCAC CTGTCCAAGA TGCAGCAGAA CGGCTACGAA 
AATCCAACCT ACAAGTTCTT TGAGCAGATG CAGAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_001204303.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191232.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 10, mRNA.

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CloneID	OHu27287
Clone ID Related Accession (Same CDS sequence)	NM_001204303.1 , NM_001204303.2
Accession Version	NM_001204303.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2034bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform j precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, Y00264.1 and BM876312.1. Transcript Variant: This variant (10) lacks three alternate in-frame exons compared to variant 1. The resulting isoform (j, also known as L-APP677) has the same N- and C-termini but is shorter compared to isoform a. No full-length transcript is available for this transcript; however, it is supported by PMID:1429732 and other publications. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: PMID: 1429732 Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGTTCCT ACAACAGCAG CCAGTACCCC TGATGCCGTT 
GACAAGTATC TCGAGACACC TGGGGATGAG AATGAACATG CCCATTTCCA GAAAGCCAAA 
GAGAGGCTTG AGGCCAAGCA CCGAGAGAGA ATGTCCCAGG TCATGAGAGA ATGGGAAGAG 
GCAGAACGTC AAGCAAAGAA CTTGCCTAAA GCTGATAAGA AGGCAGTTAT CCAGCATTTC 
CAGGAGAAAG TGGAATCTTT GGAACAGGAA GCAGCCAACG AGAGACAGCA GCTGGTGGAG 
ACACACATGG CCAGAGTGGA AGCCATGCTC AATGACCGCC GCCGCCTGGC CCTGGAGAAC 
TACATCACCG CTCTGCAGGC TGTTCCTCCT CGGCCTCGTC ACGTGTTCAA TATGCTAAAG 
AAGTATGTCC GCGCAGAACA GAAGGACAGA CAGCACACCC TAAAGCATTT CGAGCATGTG 
CGCATGGTGG ATCCCAAGAA AGCCGCTCAG ATCCGGTCCC AGGTTATGAC ACACCTCCGT 
GTGATTTATG AGCGCATGAA TCAGTCTCTC TCCCTGCTCT ACAACGTGCC TGCAGTGGCC 
GAGGAGATTC AGGATGAAGT TGATGAGCTG CTTCAGAAAG AGCAAAACTA TTCAGATGAC 
GTCTTGGCCA ACATGATTAG TGAACCAAGG ATCAGTTACG GAAACGATGC TCTCATGCCA 
TCTTTGACCG AAACGAAAAC CACCGTGGAG CTCCTTCCCG TGAATGGAGA GTTCAGCCTG 
GACGATCTCC AGCCGTGGCA TTCTTTTGGG GCTGACTCTG TGCCAGCCAA CACAGAAAAC 
GAAGGTTCTG GGTTGACAAA TATCAAGACG GAGGAGATCT CTGAAGTGAA GATGGATGCA 
GAATTCCGAC ATGACTCAGG ATATGAAGTT CATCATCAAA AATTGGTGTT CTTTGCAGAA 
GATGTGGGTT CAAACAAAGG TGCAATCATT GGACTCATGG TGGGCGGTGT TGTCATAGCG 
ACAGTGATCG TCATCACCTT GGTGATGCTG AAGAAGAAAC AGTACACATC CATTCATCAT 
GGTGTGGTGG AGGTTGACGC CGCTGTCACC CCAGAGGAGC GCCACCTGTC CAAGATGCAG 
CAGAACGGCT ACGAAAATCC AACCTACAAG TTCTTTGAGC AGATGCAGAA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191232.1
CDS	201..2234
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_001204303.1
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204303.1

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGTTCCT ACAACAGCAG CCAGTACCCC TGATGCCGTT 
GACAAGTATC TCGAGACACC TGGGGATGAG AATGAACATG CCCATTTCCA GAAAGCCAAA 
GAGAGGCTTG AGGCCAAGCA CCGAGAGAGA ATGTCCCAGG TCATGAGAGA ATGGGAAGAG 
GCAGAACGTC AAGCAAAGAA CTTGCCTAAA GCTGATAAGA AGGCAGTTAT CCAGCATTTC 
CAGGAGAAAG TGGAATCTTT GGAACAGGAA GCAGCCAACG AGAGACAGCA GCTGGTGGAG 
ACACACATGG CCAGAGTGGA AGCCATGCTC AATGACCGCC GCCGCCTGGC CCTGGAGAAC 
TACATCACCG CTCTGCAGGC TGTTCCTCCT CGGCCTCGTC ACGTGTTCAA TATGCTAAAG 
AAGTATGTCC GCGCAGAACA GAAGGACAGA CAGCACACCC TAAAGCATTT CGAGCATGTG 
CGCATGGTGG ATCCCAAGAA AGCCGCTCAG ATCCGGTCCC AGGTTATGAC ACACCTCCGT 
GTGATTTATG AGCGCATGAA TCAGTCTCTC TCCCTGCTCT ACAACGTGCC TGCAGTGGCC 
GAGGAGATTC AGGATGAAGT TGATGAGCTG CTTCAGAAAG AGCAAAACTA TTCAGATGAC 
GTCTTGGCCA ACATGATTAG TGAACCAAGG ATCAGTTACG GAAACGATGC TCTCATGCCA 
TCTTTGACCG AAACGAAAAC CACCGTGGAG CTCCTTCCCG TGAATGGAGA GTTCAGCCTG 
GACGATCTCC AGCCGTGGCA TTCTTTTGGG GCTGACTCTG TGCCAGCCAA CACAGAAAAC 
GAAGGTTCTG GGTTGACAAA TATCAAGACG GAGGAGATCT CTGAAGTGAA GATGGATGCA 
GAATTCCGAC ATGACTCAGG ATATGAAGTT CATCATCAAA AATTGGTGTT CTTTGCAGAA 
GATGTGGGTT CAAACAAAGG TGCAATCATT GGACTCATGG TGGGCGGTGT TGTCATAGCG 
ACAGTGATCG TCATCACCTT GGTGATGCTG AAGAAGAAAC AGTACACATC CATTCATCAT 
GGTGTGGTGG AGGTTGACGC CGCTGTCACC CCAGAGGAGC GCCACCTGTC CAAGATGCAG 
CAGAACGGCT ACGAAAATCC AACCTACAAG TTCTTTGAGC AGATGCAGAA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_001204303.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191232.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 10, mRNA.

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CloneID	OHu27287
Clone ID Related Accession (Same CDS sequence)	NM_001204303.1 , NM_001204303.2
Accession Version	NM_001204303.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2034bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform j precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, Y00264.1 and BM876312.1. On Jun 1, 2019 this sequence version replaced NM_001204303.1. Transcript Variant: This variant (10) lacks three alternate in-frame exons compared to variant 1. The resulting isoform (j, also known as L-APP677) has the same N- and C-termini but is shorter compared to isoform a. No full-length transcript is available for this transcript; however, it is supported by PMID:1429732 and other publications. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: PMID: 1429732 Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGTTCCT ACAACAGCAG CCAGTACCCC TGATGCCGTT 
GACAAGTATC TCGAGACACC TGGGGATGAG AATGAACATG CCCATTTCCA GAAAGCCAAA 
GAGAGGCTTG AGGCCAAGCA CCGAGAGAGA ATGTCCCAGG TCATGAGAGA ATGGGAAGAG 
GCAGAACGTC AAGCAAAGAA CTTGCCTAAA GCTGATAAGA AGGCAGTTAT CCAGCATTTC 
CAGGAGAAAG TGGAATCTTT GGAACAGGAA GCAGCCAACG AGAGACAGCA GCTGGTGGAG 
ACACACATGG CCAGAGTGGA AGCCATGCTC AATGACCGCC GCCGCCTGGC CCTGGAGAAC 
TACATCACCG CTCTGCAGGC TGTTCCTCCT CGGCCTCGTC ACGTGTTCAA TATGCTAAAG 
AAGTATGTCC GCGCAGAACA GAAGGACAGA CAGCACACCC TAAAGCATTT CGAGCATGTG 
CGCATGGTGG ATCCCAAGAA AGCCGCTCAG ATCCGGTCCC AGGTTATGAC ACACCTCCGT 
GTGATTTATG AGCGCATGAA TCAGTCTCTC TCCCTGCTCT ACAACGTGCC TGCAGTGGCC 
GAGGAGATTC AGGATGAAGT TGATGAGCTG CTTCAGAAAG AGCAAAACTA TTCAGATGAC 
GTCTTGGCCA ACATGATTAG TGAACCAAGG ATCAGTTACG GAAACGATGC TCTCATGCCA 
TCTTTGACCG AAACGAAAAC CACCGTGGAG CTCCTTCCCG TGAATGGAGA GTTCAGCCTG 
GACGATCTCC AGCCGTGGCA TTCTTTTGGG GCTGACTCTG TGCCAGCCAA CACAGAAAAC 
GAAGGTTCTG GGTTGACAAA TATCAAGACG GAGGAGATCT CTGAAGTGAA GATGGATGCA 
GAATTCCGAC ATGACTCAGG ATATGAAGTT CATCATCAAA AATTGGTGTT CTTTGCAGAA 
GATGTGGGTT CAAACAAAGG TGCAATCATT GGACTCATGG TGGGCGGTGT TGTCATAGCG 
ACAGTGATCG TCATCACCTT GGTGATGCTG AAGAAGAAAC AGTACACATC CATTCATCAT 
GGTGTGGTGG AGGTTGACGC CGCTGTCACC CCAGAGGAGC GCCACCTGTC CAAGATGCAG 
CAGAACGGCT ACGAAAATCC AACCTACAAG TTCTTTGAGC AGATGCAGAA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191232.1
CDS	151..2184
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_001204303.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204303.2

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGTTCCT ACAACAGCAG CCAGTACCCC TGATGCCGTT 
GACAAGTATC TCGAGACACC TGGGGATGAG AATGAACATG CCCATTTCCA GAAAGCCAAA 
GAGAGGCTTG AGGCCAAGCA CCGAGAGAGA ATGTCCCAGG TCATGAGAGA ATGGGAAGAG 
GCAGAACGTC AAGCAAAGAA CTTGCCTAAA GCTGATAAGA AGGCAGTTAT CCAGCATTTC 
CAGGAGAAAG TGGAATCTTT GGAACAGGAA GCAGCCAACG AGAGACAGCA GCTGGTGGAG 
ACACACATGG CCAGAGTGGA AGCCATGCTC AATGACCGCC GCCGCCTGGC CCTGGAGAAC 
TACATCACCG CTCTGCAGGC TGTTCCTCCT CGGCCTCGTC ACGTGTTCAA TATGCTAAAG 
AAGTATGTCC GCGCAGAACA GAAGGACAGA CAGCACACCC TAAAGCATTT CGAGCATGTG 
CGCATGGTGG ATCCCAAGAA AGCCGCTCAG ATCCGGTCCC AGGTTATGAC ACACCTCCGT 
GTGATTTATG AGCGCATGAA TCAGTCTCTC TCCCTGCTCT ACAACGTGCC TGCAGTGGCC 
GAGGAGATTC AGGATGAAGT TGATGAGCTG CTTCAGAAAG AGCAAAACTA TTCAGATGAC 
GTCTTGGCCA ACATGATTAG TGAACCAAGG ATCAGTTACG GAAACGATGC TCTCATGCCA 
TCTTTGACCG AAACGAAAAC CACCGTGGAG CTCCTTCCCG TGAATGGAGA GTTCAGCCTG 
GACGATCTCC AGCCGTGGCA TTCTTTTGGG GCTGACTCTG TGCCAGCCAA CACAGAAAAC 
GAAGGTTCTG GGTTGACAAA TATCAAGACG GAGGAGATCT CTGAAGTGAA GATGGATGCA 
GAATTCCGAC ATGACTCAGG ATATGAAGTT CATCATCAAA AATTGGTGTT CTTTGCAGAA 
GATGTGGGTT CAAACAAAGG TGCAATCATT GGACTCATGG TGGGCGGTGT TGTCATAGCG 
ACAGTGATCG TCATCACCTT GGTGATGCTG AAGAAGAAAC AGTACACATC CATTCATCAT 
GGTGTGGTGG AGGTTGACGC CGCTGTCACC CCAGAGGAGC GCCACCTGTC CAAGATGCAG 
CAGAACGGCT ACGAAAATCC AACCTACAAG TTCTTTGAGC AGATGCAGAA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_001136130.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129602.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 6, mRNA.

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CloneID	OHu27406
Clone ID Related Accession (Same CDS sequence)	NM_001136130.3 , NM_001136130.2
Accession Version	NM_001136130.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2145bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform f precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, AK294534.1, BC065523.1, BC065529.1 and BM876312.1. On May 31, 2019 this sequence version replaced NM_001136130.2. Transcript Variant: This variant (6) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (f) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294534.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTC 
TACCCTGAAC TGCAGATCAC CAATGTGGTA GAAGCCAACC AACCAGTGAC CATCCAGAAC 
TGGTGCAAGC GGGGCCGCAA GCAGTGCAAG ACCCATCCCC ACTTTGTGAT TCCCTACCGC 
TGCTTAGTTG GTGAGTTTGT AAGTGATGCC CTTCTCGTTC CTGACAAGTG CAAATTCTTA 
CACCAGGAGA GGATGGATGT TTGCGAAACT CATCTTCACT GGCACACCGT CGCCAAAGAG 
ACATGCAGTG AGAAGAGTAC CAACTTGCAT GACTACGGCA TGTTGCTGCC CTGCGGAATT 
GACAAGTTCC GAGGGGTAGA GTTTGTGTGT TGCCCACTGG CTGAAGAAAG TGACAATGTG 
GATTCTGCTG ATGCGGAGGA GGATGACTCG GATGTCTGGT GGGGCGGAGC AGACACAGAC 
TATGCAGATG GGAGTGAAGA CAAAGTAGTA GAAGTAGCAG AGGAGGAAGA AGTGGCTGAG 
GTGGAAGAAG AAGAAGCCGA TGATGACGAG GACGATGAGG ATGGTGATGA GGTAGAGGAA 
GAGGCTGAGG AACCCTACGA AGAAGCCACA GAGAGAACCA CCAGCATTGC CACCACCACC 
ACCACCACCA CAGAGTCTGT GGAAGAGGTG GTTCGAGAGG TGTGCTCTGA ACAAGCCGAG 
ACGGGGCCGT GCCGAGCAAT GATCTCCCGC TGGTACTTTG ATGTGACTGA AGGGAAGTGT 
GCCCCATTCT TTTACGGCGG ATGTGGCGGC AACCGGAACA ACTTTGACAC AGAAGAGTAC 
TGCATGGCCG TGTGTGGCAG CGCCATGTCC CAAAGTTTAC TCAAGACTAC CCAGGAACCT 
CTTGCCCGAG ATCCTGTTAA ACTTCCTACA ACAGCAGCCA GTACCCCTGA TGCCGTTGAC 
AAGTATCTCG AGACACCTGG GGATGAGAAT GAACATGCCC ATTTCCAGAA AGCCAAAGAG 
AGGCTTGAGG CCAAGCACCG AGAGAGAATG TCCCAGGTCA TGAGAGAATG GGAAGAGGCA 
GAACGTCAAG CAAAGAACTT GCCTAAAGCT GATAAGAAGG CAGTTATCCA GCATTTCCAG 
GAGAAAGTGG AATCTTTGGA ACAGGAAGCA GCCAACGAGA GACAGCAGCT GGTGGAGACA 
CACATGGCCA GAGTGGAAGC CATGCTCAAT GACCGCCGCC GCCTGGCCCT GGAGAACTAC 
ATCACCGCTC TGCAGGCTGT TCCTCCTCGG CCTCGTCACG TGTTCAATAT GCTAAAGAAG 
TATGTCCGCG CAGAACAGAA GGACAGACAG CACACCCTAA AGCATTTCGA GCATGTGCGC 
ATGGTGGATC CCAAGAAAGC CGCTCAGATC CGGTCCCAGG TTATGACACA CCTCCGTGTG 
ATTTATGAGC GCATGAATCA GTCTCTCTCC CTGCTCTACA ACGTGCCTGC AGTGGCCGAG 
GAGATTCAGG ATGAAGTTGA TGAGCTGCTT CAGAAAGAGC AAAACTATTC AGATGACGTC 
TTGGCCAACA TGATTAGTGA ACCAAGGATC AGTTACGGAA ACGATGCTCT CATGCCATCT 
TTGACCGAAA CGAAAACCAC CGTGGAGCTC CTTCCCGTGA ATGGAGAGTT CAGCCTGGAC 
GATCTCCAGC CGTGGCATTC TTTTGGGGCT GACTCTGTGC CAGCCAACAC AGAAAACGAA 
GTTGAGCCTG TTGATGCCCG CCCTGCTGCC GACCGAGGAC TGACCACTCG ACCAGGTTCT 
GGGTTGACAA ATATCAAGAC GGAGGAGATC TCTGAAGTGA AGATGGATGC AGAATTCCGA 
CATGACTCAG GATATGAAGT TCATCATCAA AAATTGGTGT TCTTTGCAGA AGATGTGGGT 
TCAAACAAAG GTGCAATCAT TGGACTCATG GTGGGCGGTG TTGTCATAGC GACAGTGATC 
GTCATCACCT TGGTGATGCT GAAGAAGAAA CAGTACACAT CCATTCATCA TGGTGTGGTG 
GAGGTTGACG CCGCTGTCAC CCCAGAGGAG CGCCACCTGT CCAAGATGCA GCAGAACGGC 
TACGAAAATC CAACCTACAA GTTCTTTGAG CAGATGCAGA ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129602.1
CDS	151..2295
Translation	MLPGLALLLLAAWTARALEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_001136130.3
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001136130.3

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTC 
TACCCTGAAC TGCAGATCAC CAATGTGGTA GAAGCCAACC AACCAGTGAC CATCCAGAAC 
TGGTGCAAGC GGGGCCGCAA GCAGTGCAAG ACCCATCCCC ACTTTGTGAT TCCCTACCGC 
TGCTTAGTTG GTGAGTTTGT AAGTGATGCC CTTCTCGTTC CTGACAAGTG CAAATTCTTA 
CACCAGGAGA GGATGGATGT TTGCGAAACT CATCTTCACT GGCACACCGT CGCCAAAGAG 
ACATGCAGTG AGAAGAGTAC CAACTTGCAT GACTACGGCA TGTTGCTGCC CTGCGGAATT 
GACAAGTTCC GAGGGGTAGA GTTTGTGTGT TGCCCACTGG CTGAAGAAAG TGACAATGTG 
GATTCTGCTG ATGCGGAGGA GGATGACTCG GATGTCTGGT GGGGCGGAGC AGACACAGAC 
TATGCAGATG GGAGTGAAGA CAAAGTAGTA GAAGTAGCAG AGGAGGAAGA AGTGGCTGAG 
GTGGAAGAAG AAGAAGCCGA TGATGACGAG GACGATGAGG ATGGTGATGA GGTAGAGGAA 
GAGGCTGAGG AACCCTACGA AGAAGCCACA GAGAGAACCA CCAGCATTGC CACCACCACC 
ACCACCACCA CAGAGTCTGT GGAAGAGGTG GTTCGAGAGG TGTGCTCTGA ACAAGCCGAG 
ACGGGGCCGT GCCGAGCAAT GATCTCCCGC TGGTACTTTG ATGTGACTGA AGGGAAGTGT 
GCCCCATTCT TTTACGGCGG ATGTGGCGGC AACCGGAACA ACTTTGACAC AGAAGAGTAC 
TGCATGGCCG TGTGTGGCAG CGCCATGTCC CAAAGTTTAC TCAAGACTAC CCAGGAACCT 
CTTGCCCGAG ATCCTGTTAA ACTTCCTACA ACAGCAGCCA GTACCCCTGA TGCCGTTGAC 
AAGTATCTCG AGACACCTGG GGATGAGAAT GAACATGCCC ATTTCCAGAA AGCCAAAGAG 
AGGCTTGAGG CCAAGCACCG AGAGAGAATG TCCCAGGTCA TGAGAGAATG GGAAGAGGCA 
GAACGTCAAG CAAAGAACTT GCCTAAAGCT GATAAGAAGG CAGTTATCCA GCATTTCCAG 
GAGAAAGTGG AATCTTTGGA ACAGGAAGCA GCCAACGAGA GACAGCAGCT GGTGGAGACA 
CACATGGCCA GAGTGGAAGC CATGCTCAAT GACCGCCGCC GCCTGGCCCT GGAGAACTAC 
ATCACCGCTC TGCAGGCTGT TCCTCCTCGG CCTCGTCACG TGTTCAATAT GCTAAAGAAG 
TATGTCCGCG CAGAACAGAA GGACAGACAG CACACCCTAA AGCATTTCGA GCATGTGCGC 
ATGGTGGATC CCAAGAAAGC CGCTCAGATC CGGTCCCAGG TTATGACACA CCTCCGTGTG 
ATTTATGAGC GCATGAATCA GTCTCTCTCC CTGCTCTACA ACGTGCCTGC AGTGGCCGAG 
GAGATTCAGG ATGAAGTTGA TGAGCTGCTT CAGAAAGAGC AAAACTATTC AGATGACGTC 
TTGGCCAACA TGATTAGTGA ACCAAGGATC AGTTACGGAA ACGATGCTCT CATGCCATCT 
TTGACCGAAA CGAAAACCAC CGTGGAGCTC CTTCCCGTGA ATGGAGAGTT CAGCCTGGAC 
GATCTCCAGC CGTGGCATTC TTTTGGGGCT GACTCTGTGC CAGCCAACAC AGAAAACGAA 
GTTGAGCCTG TTGATGCCCG CCCTGCTGCC GACCGAGGAC TGACCACTCG ACCAGGTTCT 
GGGTTGACAA ATATCAAGAC GGAGGAGATC TCTGAAGTGA AGATGGATGC AGAATTCCGA 
CATGACTCAG GATATGAAGT TCATCATCAA AAATTGGTGT TCTTTGCAGA AGATGTGGGT 
TCAAACAAAG GTGCAATCAT TGGACTCATG GTGGGCGGTG TTGTCATAGC GACAGTGATC 
GTCATCACCT TGGTGATGCT GAAGAAGAAA CAGTACACAT CCATTCATCA TGGTGTGGTG 
GAGGTTGACG CCGCTGTCAC CCCAGAGGAG CGCCACCTGT CCAAGATGCA GCAGAACGGC 
TACGAAAATC CAACCTACAA GTTCTTTGAG CAGATGCAGA ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( NM_001136130.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129602.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant 6, mRNA.

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CloneID	OHu27406
Clone ID Related Accession (Same CDS sequence)	NM_001136130.3 , NM_001136130.2
Accession Version	NM_001136130.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2145bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform f precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI559391.1, AK294534.1, BC065523.1, BC065529.1 and BM876312.1. On Apr 29, 2009 this sequence version replaced NM_001136130.1. Transcript Variant: This variant (6) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (f) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294534.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 20209079 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTC 
TACCCTGAAC TGCAGATCAC CAATGTGGTA GAAGCCAACC AACCAGTGAC CATCCAGAAC 
TGGTGCAAGC GGGGCCGCAA GCAGTGCAAG ACCCATCCCC ACTTTGTGAT TCCCTACCGC 
TGCTTAGTTG GTGAGTTTGT AAGTGATGCC CTTCTCGTTC CTGACAAGTG CAAATTCTTA 
CACCAGGAGA GGATGGATGT TTGCGAAACT CATCTTCACT GGCACACCGT CGCCAAAGAG 
ACATGCAGTG AGAAGAGTAC CAACTTGCAT GACTACGGCA TGTTGCTGCC CTGCGGAATT 
GACAAGTTCC GAGGGGTAGA GTTTGTGTGT TGCCCACTGG CTGAAGAAAG TGACAATGTG 
GATTCTGCTG ATGCGGAGGA GGATGACTCG GATGTCTGGT GGGGCGGAGC AGACACAGAC 
TATGCAGATG GGAGTGAAGA CAAAGTAGTA GAAGTAGCAG AGGAGGAAGA AGTGGCTGAG 
GTGGAAGAAG AAGAAGCCGA TGATGACGAG GACGATGAGG ATGGTGATGA GGTAGAGGAA 
GAGGCTGAGG AACCCTACGA AGAAGCCACA GAGAGAACCA CCAGCATTGC CACCACCACC 
ACCACCACCA CAGAGTCTGT GGAAGAGGTG GTTCGAGAGG TGTGCTCTGA ACAAGCCGAG 
ACGGGGCCGT GCCGAGCAAT GATCTCCCGC TGGTACTTTG ATGTGACTGA AGGGAAGTGT 
GCCCCATTCT TTTACGGCGG ATGTGGCGGC AACCGGAACA ACTTTGACAC AGAAGAGTAC 
TGCATGGCCG TGTGTGGCAG CGCCATGTCC CAAAGTTTAC TCAAGACTAC CCAGGAACCT 
CTTGCCCGAG ATCCTGTTAA ACTTCCTACA ACAGCAGCCA GTACCCCTGA TGCCGTTGAC 
AAGTATCTCG AGACACCTGG GGATGAGAAT GAACATGCCC ATTTCCAGAA AGCCAAAGAG 
AGGCTTGAGG CCAAGCACCG AGAGAGAATG TCCCAGGTCA TGAGAGAATG GGAAGAGGCA 
GAACGTCAAG CAAAGAACTT GCCTAAAGCT GATAAGAAGG CAGTTATCCA GCATTTCCAG 
GAGAAAGTGG AATCTTTGGA ACAGGAAGCA GCCAACGAGA GACAGCAGCT GGTGGAGACA 
CACATGGCCA GAGTGGAAGC CATGCTCAAT GACCGCCGCC GCCTGGCCCT GGAGAACTAC 
ATCACCGCTC TGCAGGCTGT TCCTCCTCGG CCTCGTCACG TGTTCAATAT GCTAAAGAAG 
TATGTCCGCG CAGAACAGAA GGACAGACAG CACACCCTAA AGCATTTCGA GCATGTGCGC 
ATGGTGGATC CCAAGAAAGC CGCTCAGATC CGGTCCCAGG TTATGACACA CCTCCGTGTG 
ATTTATGAGC GCATGAATCA GTCTCTCTCC CTGCTCTACA ACGTGCCTGC AGTGGCCGAG 
GAGATTCAGG ATGAAGTTGA TGAGCTGCTT CAGAAAGAGC AAAACTATTC AGATGACGTC 
TTGGCCAACA TGATTAGTGA ACCAAGGATC AGTTACGGAA ACGATGCTCT CATGCCATCT 
TTGACCGAAA CGAAAACCAC CGTGGAGCTC CTTCCCGTGA ATGGAGAGTT CAGCCTGGAC 
GATCTCCAGC CGTGGCATTC TTTTGGGGCT GACTCTGTGC CAGCCAACAC AGAAAACGAA 
GTTGAGCCTG TTGATGCCCG CCCTGCTGCC GACCGAGGAC TGACCACTCG ACCAGGTTCT 
GGGTTGACAA ATATCAAGAC GGAGGAGATC TCTGAAGTGA AGATGGATGC AGAATTCCGA 
CATGACTCAG GATATGAAGT TCATCATCAA AAATTGGTGT TCTTTGCAGA AGATGTGGGT 
TCAAACAAAG GTGCAATCAT TGGACTCATG GTGGGCGGTG TTGTCATAGC GACAGTGATC 
GTCATCACCT TGGTGATGCT GAAGAAGAAA CAGTACACAT CCATTCATCA TGGTGTGGTG 
GAGGTTGACG CCGCTGTCAC CCCAGAGGAG CGCCACCTGT CCAAGATGCA GCAGAACGGC 
TACGAAAATC CAACCTACAA GTTCTTTGAG CAGATGCAGA ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129602.1
CDS	201..2345
Translation	MLPGLALLLLAAWTARALEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Target ORF information:

RefSeq Version	NM_001136130.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001136130.2

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTC 
TACCCTGAAC TGCAGATCAC CAATGTGGTA GAAGCCAACC AACCAGTGAC CATCCAGAAC 
TGGTGCAAGC GGGGCCGCAA GCAGTGCAAG ACCCATCCCC ACTTTGTGAT TCCCTACCGC 
TGCTTAGTTG GTGAGTTTGT AAGTGATGCC CTTCTCGTTC CTGACAAGTG CAAATTCTTA 
CACCAGGAGA GGATGGATGT TTGCGAAACT CATCTTCACT GGCACACCGT CGCCAAAGAG 
ACATGCAGTG AGAAGAGTAC CAACTTGCAT GACTACGGCA TGTTGCTGCC CTGCGGAATT 
GACAAGTTCC GAGGGGTAGA GTTTGTGTGT TGCCCACTGG CTGAAGAAAG TGACAATGTG 
GATTCTGCTG ATGCGGAGGA GGATGACTCG GATGTCTGGT GGGGCGGAGC AGACACAGAC 
TATGCAGATG GGAGTGAAGA CAAAGTAGTA GAAGTAGCAG AGGAGGAAGA AGTGGCTGAG 
GTGGAAGAAG AAGAAGCCGA TGATGACGAG GACGATGAGG ATGGTGATGA GGTAGAGGAA 
GAGGCTGAGG AACCCTACGA AGAAGCCACA GAGAGAACCA CCAGCATTGC CACCACCACC 
ACCACCACCA CAGAGTCTGT GGAAGAGGTG GTTCGAGAGG TGTGCTCTGA ACAAGCCGAG 
ACGGGGCCGT GCCGAGCAAT GATCTCCCGC TGGTACTTTG ATGTGACTGA AGGGAAGTGT 
GCCCCATTCT TTTACGGCGG ATGTGGCGGC AACCGGAACA ACTTTGACAC AGAAGAGTAC 
TGCATGGCCG TGTGTGGCAG CGCCATGTCC CAAAGTTTAC TCAAGACTAC CCAGGAACCT 
CTTGCCCGAG ATCCTGTTAA ACTTCCTACA ACAGCAGCCA GTACCCCTGA TGCCGTTGAC 
AAGTATCTCG AGACACCTGG GGATGAGAAT GAACATGCCC ATTTCCAGAA AGCCAAAGAG 
AGGCTTGAGG CCAAGCACCG AGAGAGAATG TCCCAGGTCA TGAGAGAATG GGAAGAGGCA 
GAACGTCAAG CAAAGAACTT GCCTAAAGCT GATAAGAAGG CAGTTATCCA GCATTTCCAG 
GAGAAAGTGG AATCTTTGGA ACAGGAAGCA GCCAACGAGA GACAGCAGCT GGTGGAGACA 
CACATGGCCA GAGTGGAAGC CATGCTCAAT GACCGCCGCC GCCTGGCCCT GGAGAACTAC 
ATCACCGCTC TGCAGGCTGT TCCTCCTCGG CCTCGTCACG TGTTCAATAT GCTAAAGAAG 
TATGTCCGCG CAGAACAGAA GGACAGACAG CACACCCTAA AGCATTTCGA GCATGTGCGC 
ATGGTGGATC CCAAGAAAGC CGCTCAGATC CGGTCCCAGG TTATGACACA CCTCCGTGTG 
ATTTATGAGC GCATGAATCA GTCTCTCTCC CTGCTCTACA ACGTGCCTGC AGTGGCCGAG 
GAGATTCAGG ATGAAGTTGA TGAGCTGCTT CAGAAAGAGC AAAACTATTC AGATGACGTC 
TTGGCCAACA TGATTAGTGA ACCAAGGATC AGTTACGGAA ACGATGCTCT CATGCCATCT 
TTGACCGAAA CGAAAACCAC CGTGGAGCTC CTTCCCGTGA ATGGAGAGTT CAGCCTGGAC 
GATCTCCAGC CGTGGCATTC TTTTGGGGCT GACTCTGTGC CAGCCAACAC AGAAAACGAA 
GTTGAGCCTG TTGATGCCCG CCCTGCTGCC GACCGAGGAC TGACCACTCG ACCAGGTTCT 
GGGTTGACAA ATATCAAGAC GGAGGAGATC TCTGAAGTGA AGATGGATGC AGAATTCCGA 
CATGACTCAG GATATGAAGT TCATCATCAA AAATTGGTGT TCTTTGCAGA AGATGTGGGT 
TCAAACAAAG GTGCAATCAT TGGACTCATG GTGGGCGGTG TTGTCATAGC GACAGTGATC 
GTCATCACCT TGGTGATGCT GAAGAAGAAA CAGTACACAT CCATTCATCA TGGTGTGGTG 
GAGGTTGACG CCGCTGTCAC CCCAGAGGAG CGCCACCTGT CCAAGATGCA GCAGAACGGC 
TACGAAAATC CAACCTACAA GTTCTTTGAG CAGATGCAGA ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APP ( XM_024452075.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307843.1 Homo sapiens amyloid beta precursor protein (APP), transcript variant X1, mRNA.

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CloneID	OHu105175
Clone ID Related Accession (Same CDS sequence)	XM_024452075.1
Accession Version	XM_024452075.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	amyloid-beta precursor protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATTCCTAC AACAGCAGCC AGTACCCCTG ATGCCGTTGA CAAGTATCTC 
GAGACACCTG GGGATGAGAA TGAACATGCC CATTTCCAGA AAGCCAAAGA GAGGCTTGAG 
GCCAAGCACC GAGAGAGAAT GTCCCAGGTC ATGAGAGAAT GGGAAGAGGC AGAACGTCAA 
GCAAAGAACT TGCCTAAAGC TGATAAGAAG GCAGTTATCC AGCATTTCCA GGAGAAAGTG 
GAATCTTTGG AACAGGAAGC AGCCAACGAG AGACAGCAGC TGGTGGAGAC ACACATGGCC 
AGAGTGGAAG CCATGCTCAA TGACCGCCGC CGCCTGGCCC TGGAGAACTA CATCACCGCT 
CTGCAGGCTG TTCCTCCTCG GCCTCGTCAC GTGTTCAATA TGCTAAAGAA GTATGTCCGC 
GCAGAACAGA AGGACAGACA GCACACCCTA AAGCATTTCG AGCATGTGCG CATGGTGGAT 
CCCAAGAAAG CCGCTCAGAT CCGGTCCCAG GTTATGACAC ACCTCCGTGT GATTTATGAG 
CGCATGAATC AGTCTCTCTC CCTGCTCTAC AACGTGCCTG CAGTGGCCGA GGAGATTCAG 
GATGAAGTTG GTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307843.1
CDS	151..1788
Translation	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVGK

Target ORF information:

RefSeq Version	XM_024452075.1
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein (APP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452075.1

ORF Insert Sequence:

ATGCTGCCCG GTTTGGCACT GCTCCTGCTG GCCGCCTGGA CGGCTCGGGC GCTGGAGGTA 
CCCACTGATG GTAATGCTGG CCTGCTGGCT GAACCCCAGA TTGCCATGTT CTGTGGCAGA 
CTGAACATGC ACATGAATGT CCAGAATGGG AAGTGGGATT CAGATCCATC AGGGACCAAA 
ACCTGCATTG ATACCAAGGA AGGCATCCTG CAGTATTGCC AAGAAGTCTA CCCTGAACTG 
CAGATCACCA ATGTGGTAGA AGCCAACCAA CCAGTGACCA TCCAGAACTG GTGCAAGCGG 
GGCCGCAAGC AGTGCAAGAC CCATCCCCAC TTTGTGATTC CCTACCGCTG CTTAGTTGGT 
GAGTTTGTAA GTGATGCCCT TCTCGTTCCT GACAAGTGCA AATTCTTACA CCAGGAGAGG 
ATGGATGTTT GCGAAACTCA TCTTCACTGG CACACCGTCG CCAAAGAGAC ATGCAGTGAG 
AAGAGTACCA ACTTGCATGA CTACGGCATG TTGCTGCCCT GCGGAATTGA CAAGTTCCGA 
GGGGTAGAGT TTGTGTGTTG CCCACTGGCT GAAGAAAGTG ACAATGTGGA TTCTGCTGAT 
GCGGAGGAGG ATGACTCGGA TGTCTGGTGG GGCGGAGCAG ACACAGACTA TGCAGATGGG 
AGTGAAGACA AAGTAGTAGA AGTAGCAGAG GAGGAAGAAG TGGCTGAGGT GGAAGAAGAA 
GAAGCCGATG ATGACGAGGA CGATGAGGAT GGTGATGAGG TAGAGGAAGA GGCTGAGGAA 
CCCTACGAAG AAGCCACAGA GAGAACCACC AGCATTGCCA CCACCACCAC CACCACCACA 
GAGTCTGTGG AAGAGGTGGT TCGAGAGGTG TGCTCTGAAC AAGCCGAGAC GGGGCCGTGC 
CGAGCAATGA TCTCCCGCTG GTACTTTGAT GTGACTGAAG GGAAGTGTGC CCCATTCTTT 
TACGGCGGAT GTGGCGGCAA CCGGAACAAC TTTGACACAG AAGAGTACTG CATGGCCGTG 
TGTGGCAGCG CCATTCCTAC AACAGCAGCC AGTACCCCTG ATGCCGTTGA CAAGTATCTC 
GAGACACCTG GGGATGAGAA TGAACATGCC CATTTCCAGA AAGCCAAAGA GAGGCTTGAG 
GCCAAGCACC GAGAGAGAAT GTCCCAGGTC ATGAGAGAAT GGGAAGAGGC AGAACGTCAA 
GCAAAGAACT TGCCTAAAGC TGATAAGAAG GCAGTTATCC AGCATTTCCA GGAGAAAGTG 
GAATCTTTGG AACAGGAAGC AGCCAACGAG AGACAGCAGC TGGTGGAGAC ACACATGGCC 
AGAGTGGAAG CCATGCTCAA TGACCGCCGC CGCCTGGCCC TGGAGAACTA CATCACCGCT 
CTGCAGGCTG TTCCTCCTCG GCCTCGTCAC GTGTTCAATA TGCTAAAGAA GTATGTCCGC 
GCAGAACAGA AGGACAGACA GCACACCCTA AAGCATTTCG AGCATGTGCG CATGGTGGAT 
CCCAAGAAAG CCGCTCAGAT CCGGTCCCAG GTTATGACAC ACCTCCGTGT GATTTATGAG 
CGCATGAATC AGTCTCTCTC CCTGCTCTAC AACGTGCCTG CAGTGGCCGA GGAGATTCAG 
GATGAAGTTG GTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	APP
Entrez Gene ID	351
Full Name	amyloid beta precursor protein
Synonyms	AAA,ABETA,ABPP,AD1,APPI,CTFgamma,CVAP,PN-II,PN2,preA4
General protein information	Preferred Names amyloid beta precursor protein Names amyloid-beta A4 protein alzheimer disease amyloid protein amyloid beta (A4) precursor protein amyloid beta A4 protein amyloid precursor protein beta-amyloid peptide beta-amyloid peptide(1-40) beta-amyloid peptide(1-42) beta-amyloid precursor protein cerebral vascular amyloid peptide peptidase nexin-II protease nexin-II testicular tissue protein Li 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 21 Map Location: 21q21.3
Summary	This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014].
Disorder MIM:	104760
Disorder Html:	Cerebral amyloid angiopathy, Dutch, Italian, Iowa, Flemish, Arctic variants, 605714 (3); Alzheimer disease 1, familial, 104300 (3)

Homo sapiens (human)	APP	NP_000475.1
Bos taurus (cattle)	APP	NP_001070264.1
Pan troglodytes (chimpanzee)	APP	NP_001013036.1
Rattus norvegicus (Norway rat)	App	NP_062161.1
Caenorhabditis elegans (roundworm)	apl-1	NP_508870.3
Danio rerio (zebrafish)	appb	NP_690842.1
Canis lupus familiaris (dog)	APP	NP_001006601.1
Xenopus tropicalis (tropical clawed frog)	app	NP_001005698.1
	APP	XP_002803216.1
Mus musculus (house mouse)	App	NP_001185752.1
Gallus gallus (chicken)	APP	NP_989639.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

APP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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