LYPD5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LYPD5
Entrez Gene ID	284348
Full Name	LY6/PLAUR domain containing 5
Synonyms	PRO4356
General protein information	Preferred Names LY6/PLAUR domain containing 5 Names ly6/PLAUR domain-containing protein 5 metastasis-associated protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.31

mRNA and Protein(s)

mRNA	Protein	Name
NM_001031749.2	NP_001026919.2	ly6/PLAUR domain-containing protein 5 isoform A precursor
XM_011526794.2	XP_011525096.1	ly6/PLAUR domain-containing protein 5 isoform X1
NM_001031749.3	NP_001026919.2	ly6/PLAUR domain-containing protein 5 isoform A precursor
NM_001288763.1	NP_001275692.1	ly6/PLAUR domain-containing protein 5 isoform B
NM_182573.2	NP_872379.2	ly6/PLAUR domain-containing protein 5 isoform B

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LYPD5	XP_001158230.2
Bos taurus (cattle)	LYPD5	NP_001098494.1
Rattus norvegicus (Norway rat)	Lypd5	NP_001178939.1
Homo sapiens (human)	LYPD5	NP_001026919.2
	LOC711177	XP_001107463.1
Mus musculus (house mouse)	Lypd5	NP_084082.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of the Ly6/uPAR-domain proteins C4.4A and Haldisin in non-invasive and invasive skin lesions.
Kriegbaum MC, Clausen OP, L?rum OD, Ploug M
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society63(2)142-54(2015 02)

The correlation between reading and mathematics ability at age twelve has a substantial genetic component.
Davis OS, Band G, Pirinen M, Haworth CM, Meaburn EL, Kovas Y, Harlaar N, Docherty SJ, Hanscombe KB, Trzaskowski M, Curtis CJ, Strange A, Freeman C, Bellenguez C, Su Z, Pearson R, Vukcevic D, Langford C, Deloukas P, Hunt S, Gray E, Dronov S, Potter SC, Tashakkori-Ghanbaria A, Edkins S, Bumpstead SJ, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Duncanson A, Jankowski JA, Markus HS, Mathew CG, Palmer CN, Rautanen A, Sawcer SJ, Trembath RC, Viswanathan AC, Wood NW, Barroso I, Peltonen L, Dale PS, Petrill SA, Schalkwyk LS, Craig IW, Lewis CM, Price TS, , Donnelly P, Plomin R, Spencer CC
Nature communications54204(2014 Jul)

The urokinase receptor homolog Haldisin is a novel differentiation marker of stratum granulosum in squamous epithelia.
G?rdsvoll H, Kriegbaum MC, Hertz EP, Alp?zar-Alp?zar W, Ploug M
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society61(11)802-13(2013 Nov)

Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, , Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittom?ki K, Blomqvist C, Czene K, Irwanto A, Liu J, Waisfisz Q, Meijers-Heijboer H, Adank M, , van der Luijt RB, Hein R, Dahmen N, Beckman L, Meindl A, Schmutzler RK, M?ller-Myhsok B, Lichtner P, Hopper JL, Southey MC, Makalic E, Schmidt DF, Uitterlinden AG, Hofman A, Hunter DJ, Chanock SJ, Vincent D, Bacot F, Tessier DC, Canisius S, Wessels LF, Haiman CA, Shah M, Luben R, Brown J, Luccarini C, Schoof N, Humphreys K, Li J, Nordestgaard BG, Nielsen SF, Flyger H, Couch FJ, Wang X, Vachon C, Stevens KN, Lambrechts D, Moisse M, Paridaens R, Christiaens MR, Rudolph A, Nickels S, Flesch-Janys D, Johnson N, Aitken Z, Aaltonen K, Heikkinen T, Broeks A, Veer LJ, van der Schoot CE, Gu?nel P, Truong T, Laurent-Puig P, Menegaux F, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Zamora MP, Perez JI, Pita G, Alonso MR, Cox A, Brock IW, Cross SS, Reed MW, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Henderson BE, Schumacher F, Le Marchand L, Andrulis IL, Knight JA, Glendon G, Mulligan AM, , , Lindblom A, Margolin S, Hooning MJ, Hollestelle A, van den Ouweland AM, Jager A, Bui QM, Stone J, Dite GS, Apicella C, Tsimiklis H, Giles GG, Severi G, Baglietto L, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Brenner H, M?ller H, Arndt V, Stegmaier C, Swerdlow A, Ashworth A, Orr N, Jones M, Figueroa J, Lissowska J, Brinton L, Goldberg MS, Labr?che F, Dumont M, Winqvist R, Pylk?s K, Jukkola-Vuorinen A, Grip M, Brauch H, Hamann U, Br?ning T, , Radice P, Peterlongo P, Manoukian S, Bonanni B, Devilee P, Tollenaar RA, Seynaeve C, van Asperen CJ, Jakubowska A, Lubinski J, Jaworska K, Durda K, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Bogdanova NV, Antonenkova NN, D?rk T, Kristensen VN, Anton-Culver H, Slager S, Toland AE, Edge S, Fostira F, Kang D, Yoo KY, Noh DY, Matsuo K, Ito H, Iwata H, Sueta A, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Shu XO, Lu W, Gao YT, Cai H, Teo SH, Yip CH, Phuah SY, Cornes BK, Hartman M, Miao H, Lim WY, Sng JH, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Shen CY, Hsiung CN, Wu PE, Ding SL, Sangrajrang S, Gaborieau V, Brennan P, McKay J, Blot WJ, Signorello LB, Cai Q, Zheng W, Deming-Halverson S, Shrubsole M, Long J, Simard J, Garcia-Closas M, Pharoah PD, Chenevix-Trench G, Dunning AM, Benitez J, Easton DF
Nature genetics45(4)353-61, 361e1-2(2013 Apr)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Expression of the Ly6/uPAR-domain proteins C4.4A and Haldisin in non-invasive and invasive skin lesions
Title: Expression of the Ly6/uPAR-domain proteins C4.4A and Haldisin in non-invasive and invasive skin lesions.

The study identifies LYPD5 a novel differentiation marker of stratum granulosum in squamous epithelia.
Title: The urokinase receptor homolog Haldisin is a novel differentiation marker of stratum granulosum in squamous epithelia.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following LYPD5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LYPD5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17504	NM_001031749.3 Latest version!	Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu14536	NM_001288763.1 Latest version!	Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant C, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu14536	NM_182573.2 Latest version!	Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant B, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu14536	XM_011526794.2 Latest version!	Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu17504	NM_001031749.2	Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LYPD5 ( NM_001031749.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001026919.2 Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant A, mRNA.

Price & Availability↑

CloneID	OHu17504
Clone ID Related Accession (Same CDS sequence)	NM_001031749.2 , NM_001031749.3
Accession Version	NM_001031749.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 756bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	ly6/PLAUR domain-containing protein 5 isoform A precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC364960.1, AY358719.1, BC057816.1, BC044237.1, AC115522.2 and CF529795.1. On Nov 22, 2018 this sequence version replaced NM_001031749.2. Transcript Variant: This variant (A) encodes the longer protein (isoform A). ##Evidence-Data-START## Transcript exon combination :: BC057816.1, SRR1803615.233771.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000377950.8/ ENSP00000367185.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAATGG GGGTCCCCAG AGTCATTCTG CTCTGCCTCT TTGGGGCTGC GCTCTGCCTG 
ACAGGGTCCC AAGCCCTGCA GTGCTACAGC TTTGAGCACA CCTACTTTGG CCCCTTTGAC 
CTCAGGGCCA TGAAGCTGCC CAGCATCTCC TGTCCTCATG AGTGCTTTGA GGCTATCCTG 
TCTCTGGACA CCGGGTATCG CGCGCCGGTG ACCCTGGTGC GGAAGGGCTG CTGGACCGGG 
CCTCCTGCGG GCCAGACGCA ATCGAACGCG GACGCGCTGC CGCCAGACTA CTCGGTGGTG 
CGCGGCTGCA CAACTGACAA ATGCAACGCC CACCTCATGA CTCATGACGC CCTCCCCAAC 
CTGAGCCAAG CACCCGACCC GCCGACGCTC AGCGGCGCCG AGTGCTACGC CTGTATCGGG 
GTCCACCAGG ATGACTGCGC TATCGGCAGG TCCCGACGAG TCCAGTGTCA CCAGGACCAG 
ACCGCCTGCT TCCAGGGCAA TGGCAGAATG ACAGTTGGCA ATTTCTCAGT CCCTGTGTAC 
ATCAGAACCT GCCACCGGCC CTCCTGCACC ACCGAGGGCA CCACCAGCCC CTGGACAGCC 
ATCGACCTCC AGGGCTCCTG CTGTGAGGGG TACCTCTGCA ACAGGAAATC CATGACCCAG 
CCCTTCACCA GTGCTTCAGC CACCACCCCT CCCCGAGCAC TACAGGTCCT GGCCCTGCTC 
CTCCCAGTCC TCCTGCTGGT GGGGCTCTCA GCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001026919.2
CDS	68..823
Translation	MAMGVPRVILLCLFGAALCLTGSQALQCYSFEHTYFGPFDLRAMKLPSISCPHECFEAILSLDTGYRAPVTLVRKGCWTGPPAGQTQSNADALPPDYSVVRGCTTDKCNAHLMTHDALPNLSQAPDPPTLSGAECYACIGVHQDDCAIGRSRRVQCHQDQTACFQGNGRMTVGNFSVPVYIRTCHRPSCTTEGTTSPWTAIDLQGSCCEGYLCNRKSMTQPFTSASATTPPRALQVLALLLPVLLLVGLSA

Target ORF information:

RefSeq Version	NM_001031749.3
Organism	Homo sapiens(human)
Definition	Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001031749.3

ORF Insert Sequence:

ATGGCAATGG GGGTCCCCAG AGTCATTCTG CTCTGCCTCT TTGGGGCTGC GCTCTGCCTG 
ACAGGGTCCC AAGCCCTGCA GTGCTACAGC TTTGAGCACA CCTACTTTGG CCCCTTTGAC 
CTCAGGGCCA TGAAGCTGCC CAGCATCTCC TGTCCTCATG AGTGCTTTGA GGCTATCCTG 
TCTCTGGACA CCGGGTATCG CGCGCCGGTG ACCCTGGTGC GGAAGGGCTG CTGGACCGGG 
CCTCCTGCGG GCCAGACGCA ATCGAACGCG GACGCGCTGC CGCCAGACTA CTCGGTGGTG 
CGCGGCTGCA CAACTGACAA ATGCAACGCC CACCTCATGA CTCATGACGC CCTCCCCAAC 
CTGAGCCAAG CACCCGACCC GCCGACGCTC AGCGGCGCCG AGTGCTACGC CTGTATCGGG 
GTCCACCAGG ATGACTGCGC TATCGGCAGG TCCCGACGAG TCCAGTGTCA CCAGGACCAG 
ACCGCCTGCT TCCAGGGCAA TGGCAGAATG ACAGTTGGCA ATTTCTCAGT CCCTGTGTAC 
ATCAGAACCT GCCACCGGCC CTCCTGCACC ACCGAGGGCA CCACCAGCCC CTGGACAGCC 
ATCGACCTCC AGGGCTCCTG CTGTGAGGGG TACCTCTGCA ACAGGAAATC CATGACCCAG 
CCCTTCACCA GTGCTTCAGC CACCACCCCT CCCCGAGCAC TACAGGTCCT GGCCCTGCTC 
CTCCCAGTCC TCCTGCTGGT GGGGCTCTCA GCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LYPD5 ( NM_001288763.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001275692.1 Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant C, mRNA.

Price & Availability↑

CloneID	OHu14536
Clone ID Related Accession (Same CDS sequence)	XM_011526794.2 , NM_001288763.1 , NM_182573.2
Accession Version	NM_001288763.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	ly6/PLAUR domain-containing protein 5 isoform B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA093306.1, CK823626.1, BC044237.1, AC115522.2 and CF529795.1. Transcript Variant: This variant (C) contains a distinct 5' UTR, lacks an in-frame portion of the 5' coding region and initiates translation at a downstream start codon compared to variant 1. The encoded protein (isoform B) has a distinct N-terminus and is shorter than isoform A. Variants B and C encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.261746.1, SRR1803616.50458.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGAAGCTGC CCAGCATCTC CTGTCCTCAT GAGTGCTTTG AGGCTATCCT GTCTCTGGAC 
ACCGGGTATC GCGCGCCGGT GACCCTGGTG CGGAAGGGCT GCTGGACCGG GCCTCCTGCG 
GGCCAGACGC AATCGAACGC GGACGCGCTG CCGCCAGACT ACTCGGTGGT GCGCGGCTGC 
ACAACTGACA AATGCAACGC CCACCTCATG ACTCATGACG CCCTCCCCAA CCTGAGCCAA 
GCACCCGACC CGCCGACGCT CAGCGGCGCC GAGTGCTACG CCTGTATCGG GGTCCACCAG 
GATGACTGCG CTATCGGCAG GTCCCGACGA GTCCAGTGTC ACCAGGACCA GACCGCCTGC 
TTCCAGGGCA ATGGCAGAAT GACAGTTGGC AATTTCTCAG TCCCTGTGTA CATCAGAACC 
TGCCACCGGC CCTCCTGCAC CACCGAGGGC ACCACCAGCC CCTGGACAGC CATCGACCTC 
CAGGGCTCCT GCTGTGAGGG GTACCTCTGC AACAGGAAAT CCATGACCCA GCCCTTCACC 
AGTGCTTCAG CCACCACCCC TCCCCGAGCA CTACAGGTCC TGGCCCTGCT CCTCCCAGTC 
CTCCTGCTGG TGGGGCTCTC AGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001275692.1
CDS	261..887
Translation	MKLPSISCPHECFEAILSLDTGYRAPVTLVRKGCWTGPPAGQTQSNADALPPDYSVVRGCTTDKCNAHLMTHDALPNLSQAPDPPTLSGAECYACIGVHQDDCAIGRSRRVQCHQDQTACFQGNGRMTVGNFSVPVYIRTCHRPSCTTEGTTSPWTAIDLQGSCCEGYLCNRKSMTQPFTSASATTPPRALQVLALLLPVLLLVGLSA

Target ORF information:

RefSeq Version	NM_001288763.1
Organism	Homo sapiens(human)
Definition	Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant C, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001288763.1

ORF Insert Sequence:

ATGAAGCTGC CCAGCATCTC CTGTCCTCAT GAGTGCTTTG AGGCTATCCT GTCTCTGGAC 
ACCGGGTATC GCGCGCCGGT GACCCTGGTG CGGAAGGGCT GCTGGACCGG GCCTCCTGCG 
GGCCAGACGC AATCGAACGC GGACGCGCTG CCGCCAGACT ACTCGGTGGT GCGCGGCTGC 
ACAACTGACA AATGCAACGC CCACCTCATG ACTCATGACG CCCTCCCCAA CCTGAGCCAA 
GCACCCGACC CGCCGACGCT CAGCGGCGCC GAGTGCTACG CCTGTATCGG GGTCCACCAG 
GATGACTGCG CTATCGGCAG GTCCCGACGA GTCCAGTGTC ACCAGGACCA GACCGCCTGC 
TTCCAGGGCA ATGGCAGAAT GACAGTTGGC AATTTCTCAG TCCCTGTGTA CATCAGAACC 
TGCCACCGGC CCTCCTGCAC CACCGAGGGC ACCACCAGCC CCTGGACAGC CATCGACCTC 
CAGGGCTCCT GCTGTGAGGG GTACCTCTGC AACAGGAAAT CCATGACCCA GCCCTTCACC 
AGTGCTTCAG CCACCACCCC TCCCCGAGCA CTACAGGTCC TGGCCCTGCT CCTCCCAGTC 
CTCCTGCTGG TGGGGCTCTC AGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LYPD5 ( NM_182573.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_872379.2 Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant B, mRNA.

Price & Availability↑

CloneID	OHu14536
Clone ID Related Accession (Same CDS sequence)	XM_011526794.2 , NM_001288763.1 , NM_182573.2
Accession Version	NM_182573.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	ly6/PLAUR domain-containing protein 5 isoform B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA286806.1, BC044237.1, AC115522.2 and CF529795.1. On Jan 12, 2008 this sequence version replaced NM_182573.1. Transcript Variant: This variant (B) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon compared to variant 1. The encoded protein (isoform B) has a distinct N-terminus and is shorter than isoform A. Variants B and C encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.261566.1, SRR1803614.32311.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCTGC CCAGCATCTC CTGTCCTCAT GAGTGCTTTG AGGCTATCCT GTCTCTGGAC 
ACCGGGTATC GCGCGCCGGT GACCCTGGTG CGGAAGGGCT GCTGGACCGG GCCTCCTGCG 
GGCCAGACGC AATCGAACGC GGACGCGCTG CCGCCAGACT ACTCGGTGGT GCGCGGCTGC 
ACAACTGACA AATGCAACGC CCACCTCATG ACTCATGACG CCCTCCCCAA CCTGAGCCAA 
GCACCCGACC CGCCGACGCT CAGCGGCGCC GAGTGCTACG CCTGTATCGG GGTCCACCAG 
GATGACTGCG CTATCGGCAG GTCCCGACGA GTCCAGTGTC ACCAGGACCA GACCGCCTGC 
TTCCAGGGCA ATGGCAGAAT GACAGTTGGC AATTTCTCAG TCCCTGTGTA CATCAGAACC 
TGCCACCGGC CCTCCTGCAC CACCGAGGGC ACCACCAGCC CCTGGACAGC CATCGACCTC 
CAGGGCTCCT GCTGTGAGGG GTACCTCTGC AACAGGAAAT CCATGACCCA GCCCTTCACC 
AGTGCTTCAG CCACCACCCC TCCCCGAGCA CTACAGGTCC TGGCCCTGCT CCTCCCAGTC 
CTCCTGCTGG TGGGGCTCTC AGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872379.2
CDS	183..809
Translation	MKLPSISCPHECFEAILSLDTGYRAPVTLVRKGCWTGPPAGQTQSNADALPPDYSVVRGCTTDKCNAHLMTHDALPNLSQAPDPPTLSGAECYACIGVHQDDCAIGRSRRVQCHQDQTACFQGNGRMTVGNFSVPVYIRTCHRPSCTTEGTTSPWTAIDLQGSCCEGYLCNRKSMTQPFTSASATTPPRALQVLALLLPVLLLVGLSA

Target ORF information:

RefSeq Version	NM_182573.2
Organism	Homo sapiens(human)
Definition	Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant B, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182573.2

ORF Insert Sequence:

ATGAAGCTGC CCAGCATCTC CTGTCCTCAT GAGTGCTTTG AGGCTATCCT GTCTCTGGAC 
ACCGGGTATC GCGCGCCGGT GACCCTGGTG CGGAAGGGCT GCTGGACCGG GCCTCCTGCG 
GGCCAGACGC AATCGAACGC GGACGCGCTG CCGCCAGACT ACTCGGTGGT GCGCGGCTGC 
ACAACTGACA AATGCAACGC CCACCTCATG ACTCATGACG CCCTCCCCAA CCTGAGCCAA 
GCACCCGACC CGCCGACGCT CAGCGGCGCC GAGTGCTACG CCTGTATCGG GGTCCACCAG 
GATGACTGCG CTATCGGCAG GTCCCGACGA GTCCAGTGTC ACCAGGACCA GACCGCCTGC 
TTCCAGGGCA ATGGCAGAAT GACAGTTGGC AATTTCTCAG TCCCTGTGTA CATCAGAACC 
TGCCACCGGC CCTCCTGCAC CACCGAGGGC ACCACCAGCC CCTGGACAGC CATCGACCTC 
CAGGGCTCCT GCTGTGAGGG GTACCTCTGC AACAGGAAAT CCATGACCCA GCCCTTCACC 
AGTGCTTCAG CCACCACCCC TCCCCGAGCA CTACAGGTCC TGGCCCTGCT CCTCCCAGTC 
CTCCTGCTGG TGGGGCTCTC AGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LYPD5 ( NM_001031749.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001026919.2 Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant A, mRNA.

Price & Availability↑

CloneID	OHu17504
Clone ID Related Accession (Same CDS sequence)	NM_001031749.2 , NM_001031749.3
Accession Version	NM_001031749.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 756bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	ly6/PLAUR domain-containing protein 5 isoform A precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC364960.1, AY358719.1, BC057816.1, BC044237.1, AC115522.2 and CF529795.1. On Jan 15, 2008 this sequence version replaced NM_001031749.1. Transcript Variant: This variant (A) encodes the longer protein (isoform A). ##Evidence-Data-START## Transcript exon combination :: AK301693.1, BC057816.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAATGG GGGTCCCCAG AGTCATTCTG CTCTGCCTCT TTGGGGCTGC GCTCTGCCTG 
ACAGGGTCCC AAGCCCTGCA GTGCTACAGC TTTGAGCACA CCTACTTTGG CCCCTTTGAC 
CTCAGGGCCA TGAAGCTGCC CAGCATCTCC TGTCCTCATG AGTGCTTTGA GGCTATCCTG 
TCTCTGGACA CCGGGTATCG CGCGCCGGTG ACCCTGGTGC GGAAGGGCTG CTGGACCGGG 
CCTCCTGCGG GCCAGACGCA ATCGAACGCG GACGCGCTGC CGCCAGACTA CTCGGTGGTG 
CGCGGCTGCA CAACTGACAA ATGCAACGCC CACCTCATGA CTCATGACGC CCTCCCCAAC 
CTGAGCCAAG CACCCGACCC GCCGACGCTC AGCGGCGCCG AGTGCTACGC CTGTATCGGG 
GTCCACCAGG ATGACTGCGC TATCGGCAGG TCCCGACGAG TCCAGTGTCA CCAGGACCAG 
ACCGCCTGCT TCCAGGGCAA TGGCAGAATG ACAGTTGGCA ATTTCTCAGT CCCTGTGTAC 
ATCAGAACCT GCCACCGGCC CTCCTGCACC ACCGAGGGCA CCACCAGCCC CTGGACAGCC 
ATCGACCTCC AGGGCTCCTG CTGTGAGGGG TACCTCTGCA ACAGGAAATC CATGACCCAG 
CCCTTCACCA GTGCTTCAGC CACCACCCCT CCCCGAGCAC TACAGGTCCT GGCCCTGCTC 
CTCCCAGTCC TCCTGCTGGT GGGGCTCTCA GCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001026919.2
CDS	82..837
Translation	MAMGVPRVILLCLFGAALCLTGSQALQCYSFEHTYFGPFDLRAMKLPSISCPHECFEAILSLDTGYRAPVTLVRKGCWTGPPAGQTQSNADALPPDYSVVRGCTTDKCNAHLMTHDALPNLSQAPDPPTLSGAECYACIGVHQDDCAIGRSRRVQCHQDQTACFQGNGRMTVGNFSVPVYIRTCHRPSCTTEGTTSPWTAIDLQGSCCEGYLCNRKSMTQPFTSASATTPPRALQVLALLLPVLLLVGLSA

Target ORF information:

RefSeq Version	NM_001031749.2
Organism	Homo sapiens(human)
Definition	Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001031749.2

ORF Insert Sequence:

ATGGCAATGG GGGTCCCCAG AGTCATTCTG CTCTGCCTCT TTGGGGCTGC GCTCTGCCTG 
ACAGGGTCCC AAGCCCTGCA GTGCTACAGC TTTGAGCACA CCTACTTTGG CCCCTTTGAC 
CTCAGGGCCA TGAAGCTGCC CAGCATCTCC TGTCCTCATG AGTGCTTTGA GGCTATCCTG 
TCTCTGGACA CCGGGTATCG CGCGCCGGTG ACCCTGGTGC GGAAGGGCTG CTGGACCGGG 
CCTCCTGCGG GCCAGACGCA ATCGAACGCG GACGCGCTGC CGCCAGACTA CTCGGTGGTG 
CGCGGCTGCA CAACTGACAA ATGCAACGCC CACCTCATGA CTCATGACGC CCTCCCCAAC 
CTGAGCCAAG CACCCGACCC GCCGACGCTC AGCGGCGCCG AGTGCTACGC CTGTATCGGG 
GTCCACCAGG ATGACTGCGC TATCGGCAGG TCCCGACGAG TCCAGTGTCA CCAGGACCAG 
ACCGCCTGCT TCCAGGGCAA TGGCAGAATG ACAGTTGGCA ATTTCTCAGT CCCTGTGTAC 
ATCAGAACCT GCCACCGGCC CTCCTGCACC ACCGAGGGCA CCACCAGCCC CTGGACAGCC 
ATCGACCTCC AGGGCTCCTG CTGTGAGGGG TACCTCTGCA ACAGGAAATC CATGACCCAG 
CCCTTCACCA GTGCTTCAGC CACCACCCCT CCCCGAGCAC TACAGGTCCT GGCCCTGCTC 
CTCCCAGTCC TCCTGCTGGT GGGGCTCTCA GCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LYPD5 ( XM_011526794.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011525096.1 Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant X2, mRNA.

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CloneID	OHu14536
Clone ID Related Accession (Same CDS sequence)	XM_011526794.2 , NM_001288763.1 , NM_182573.2
Accession Version	XM_011526794.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	ly6/PLAUR domain-containing protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011526794.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCTGC CCAGCATCTC CTGTCCTCAT GAGTGCTTTG AGGCTATCCT GTCTCTGGAC 
ACCGGGTATC GCGCGCCGGT GACCCTGGTG CGGAAGGGCT GCTGGACCGG GCCTCCTGCG 
GGCCAGACGC AATCGAACGC GGACGCGCTG CCGCCAGACT ACTCGGTGGT GCGCGGCTGC 
ACAACTGACA AATGCAACGC CCACCTCATG ACTCATGACG CCCTCCCCAA CCTGAGCCAA 
GCACCCGACC CGCCGACGCT CAGCGGCGCC GAGTGCTACG CCTGTATCGG GGTCCACCAG 
GATGACTGCG CTATCGGCAG GTCCCGACGA GTCCAGTGTC ACCAGGACCA GACCGCCTGC 
TTCCAGGGCA ATGGCAGAAT GACAGTTGGC AATTTCTCAG TCCCTGTGTA CATCAGAACC 
TGCCACCGGC CCTCCTGCAC CACCGAGGGC ACCACCAGCC CCTGGACAGC CATCGACCTC 
CAGGGCTCCT GCTGTGAGGG GTACCTCTGC AACAGGAAAT CCATGACCCA GCCCTTCACC 
AGTGCTTCAG CCACCACCCC TCCCCGAGCA CTACAGGTCC TGGCCCTGCT CCTCCCAGTC 
CTCCTGCTGG TGGGGCTCTC AGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011525096.1
CDS	267..893
Translation	MKLPSISCPHECFEAILSLDTGYRAPVTLVRKGCWTGPPAGQTQSNADALPPDYSVVRGCTTDKCNAHLMTHDALPNLSQAPDPPTLSGAECYACIGVHQDDCAIGRSRRVQCHQDQTACFQGNGRMTVGNFSVPVYIRTCHRPSCTTEGTTSPWTAIDLQGSCCEGYLCNRKSMTQPFTSASATTPPRALQVLALLLPVLLLVGLSA

Target ORF information:

RefSeq Version	XM_011526794.2
Organism	Homo sapiens(human)
Definition	Homo sapiens LY6/PLAUR domain containing 5 (LYPD5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526794.2

ORF Insert Sequence:

ATGAAGCTGC CCAGCATCTC CTGTCCTCAT GAGTGCTTTG AGGCTATCCT GTCTCTGGAC 
ACCGGGTATC GCGCGCCGGT GACCCTGGTG CGGAAGGGCT GCTGGACCGG GCCTCCTGCG 
GGCCAGACGC AATCGAACGC GGACGCGCTG CCGCCAGACT ACTCGGTGGT GCGCGGCTGC 
ACAACTGACA AATGCAACGC CCACCTCATG ACTCATGACG CCCTCCCCAA CCTGAGCCAA 
GCACCCGACC CGCCGACGCT CAGCGGCGCC GAGTGCTACG CCTGTATCGG GGTCCACCAG 
GATGACTGCG CTATCGGCAG GTCCCGACGA GTCCAGTGTC ACCAGGACCA GACCGCCTGC 
TTCCAGGGCA ATGGCAGAAT GACAGTTGGC AATTTCTCAG TCCCTGTGTA CATCAGAACC 
TGCCACCGGC CCTCCTGCAC CACCGAGGGC ACCACCAGCC CCTGGACAGC CATCGACCTC 
CAGGGCTCCT GCTGTGAGGG GTACCTCTGC AACAGGAAAT CCATGACCCA GCCCTTCACC 
AGTGCTTCAG CCACCACCCC TCCCCGAGCA CTACAGGTCC TGGCCCTGCT CCTCCCAGTC 
CTCCTGCTGG TGGGGCTCTC AGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of the Ly6/uPAR-domain proteins C4.4A and Haldisin in non-invasive and invasive skin lesions.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society63(2)142-54(2015 02)
Kriegbaum MC,Clausen OP,L?rum OD,Ploug M

The correlation between reading and mathematics ability at age twelve has a substantial genetic component.
Nature communications54204(2014 Jul)
Davis OS,Band G,Pirinen M,Haworth CM,Meaburn EL,Kovas Y,Harlaar N,Docherty SJ,Hanscombe KB,Trzaskowski M,Curtis CJ,Strange A,Freeman C,Bellenguez C,Su Z,Pearson R,Vukcevic D,Langford C,Deloukas P,Hunt S,Gray E,Dronov S,Potter SC,Tashakkori-Ghanbaria A,Edkins S,Bumpstead SJ,Blackwell JM,Bramon E,Brown MA,Casas JP,Corvin A,Duncanson A,Jankowski JA,Markus HS,Mathew CG,Palmer CN,Rautanen A,Sawcer SJ,Trembath RC,Viswanathan AC,Wood NW,Barroso I,Peltonen L,Dale PS,Petrill SA,Schalkwyk LS,Craig IW,Lewis CM,Price TS,,Donnelly P,Plomin R,Spencer CC

The urokinase receptor homolog Haldisin is a novel differentiation marker of stratum granulosum in squamous epithelia.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society61(11)802-13(2013 Nov)
G?rdsvoll H,Kriegbaum MC,Hertz EP,Alp?zar-Alp?zar W,Ploug M

Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
Nature genetics45(4)353-61, 361e1-2(2013 Apr)
Michailidou K,Hall P,Gonzalez-Neira A,Ghoussaini M,Dennis J,Milne RL,Schmidt MK,Chang-Claude J,Bojesen SE,Bolla MK,Wang Q,Dicks E,Lee A,Turnbull C,Rahman N,,Fletcher O,Peto J,Gibson L,Dos Santos Silva I,Nevanlinna H,Muranen TA,Aittom?ki K,Blomqvist C,Czene K,Irwanto A,Liu J,Waisfisz Q,Meijers-Heijboer H,Adank M,,van der Luijt RB,Hein R,Dahmen N,Beckman L,Meindl A,Schmutzler RK,M?ller-Myhsok B,Lichtner P,Hopper JL,Southey MC,Makalic E,Schmidt DF,Uitterlinden AG,Hofman A,Hunter DJ,Chanock SJ,Vincent D,Bacot F,Tessier DC,Canisius S,Wessels LF,Haiman CA,Shah M,Luben R,Brown J,Luccarini C,Schoof N,Humphreys K,Li J,Nordestgaard BG,Nielsen SF,Flyger H,Couch FJ,Wang X,Vachon C,Stevens KN,Lambrechts D,Moisse M,Paridaens R,Christiaens MR,Rudolph A,Nickels S,Flesch-Janys D,Johnson N,Aitken Z,Aaltonen K,Heikkinen T,Broeks A,Veer LJ,van der Schoot CE,Gu?nel P,Truong T,Laurent-Puig P,Menegaux F,Marme F,Schneeweiss A,Sohn C,Burwinkel B,Zamora MP,Perez JI,Pita G,Alonso MR,Cox A,Brock IW,Cross SS,Reed MW,Sawyer EJ,Tomlinson I,Kerin MJ,Miller N,Henderson BE,Schumacher F,Le Marchand L,Andrulis IL,Knight JA,Glendon G,Mulligan AM,,,Lindblom A,Margolin S,Hooning MJ,Hollestelle A,van den Ouweland AM,Jager A,Bui QM,Stone J,Dite GS,Apicella C,Tsimiklis H,Giles GG,Severi G,Baglietto L,Fasching PA,Haeberle L,Ekici AB,Beckmann MW,Brenner H,M?ller H,Arndt V,Stegmaier C,Swerdlow A,Ashworth A,Orr N,Jones M,Figueroa J,Lissowska J,Brinton L,Goldberg MS,Labr?che F,Dumont M,Winqvist R,Pylk?s K,Jukkola-Vuorinen A,Grip M,Brauch H,Hamann U,Br?ning T,,Radice P,Peterlongo P,Manoukian S,Bonanni B,Devilee P,Tollenaar RA,Seynaeve C,van Asperen CJ,Jakubowska A,Lubinski J,Jaworska K,Durda K,Mannermaa A,Kataja V,Kosma VM,Hartikainen JM,Bogdanova NV,Antonenkova NN,D?rk T,Kristensen VN,Anton-Culver H,Slager S,Toland AE,Edge S,Fostira F,Kang D,Yoo KY,Noh DY,Matsuo K,Ito H,Iwata H,Sueta A,Wu AH,Tseng CC,Van Den Berg D,Stram DO,Shu XO,Lu W,Gao YT,Cai H,Teo SH,Yip CH,Phuah SY,Cornes BK,Hartman M,Miao H,Lim WY,Sng JH,Muir K,Lophatananon A,Stewart-Brown S,Siriwanarangsan P,Shen CY,Hsiung CN,Wu PE,Ding SL,Sangrajrang S,Gaborieau V,Brennan P,McKay J,Blot WJ,Signorello LB,Cai Q,Zheng W,Deming-Halverson S,Shrubsole M,Long J,Simard J,Garcia-Closas M,Pharoah PD,Chenevix-Trench G,Dunning AM,Benitez J,Easton DF

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

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LYPD5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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