Gene Symbol | IFNL3 |
Entrez Gene ID | 282617 |
Full Name | interferon lambda 3 |
Synonyms | IFN-lambda-3,IFN-lambda-4,IL-28B,IL-28C,IL28B,IL28C |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(Human) |
Genome | |
Summary | This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | {Hepatitis C virus infection, response to therapy of}, 609532 (3) |