SALL3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SALL3
Entrez Gene ID	27164
Full Name	spalt like transcription factor 3
Synonyms	ZNF796
General protein information	Preferred Names spalt like transcription factor 3 Names sal-like protein 3 C2H2 zinc finger protein SALL3 hSALL3 spalt-like zinc finger protein zinc finger protein 796
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 18 Map Location: 18q23
Summary	This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis. [provided by RefSeq, Oct 2011].
Disorder MIM:	605079

mRNA and Protein(s)

mRNA	Protein	Name
NM_171999.3	NP_741996.2	sal-like protein 3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SALL3	XP_512182.2
Mus musculus (house mouse)	Sall3	NP_840064.2
Danio rerio (zebrafish)	LOC560775	XP_689264.5
Homo sapiens (human)	SALL3	NP_741996.2
Rattus norvegicus (Norway rat)	Sall3	NP_001102362.1
	SALL3	XP_001108672.2
Gallus gallus (chicken)	SALL3	NP_989978.1
Bos taurus (cattle)	SALL3	XP_003587806.2
Xenopus tropicalis (tropical clawed frog)	sall3	XP_002936493.1

Gene Ontology
Bibliography

Related articles in PubMed

Epigenetic silencing of
Misawa K, Mochizuki D, Imai A, Misawa Y, Endo S, Mima M, Kawasaki H, Carey TE, Kanazawa T
Clinical epigenetics964(2017)

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
Eeles RA, Olama AA, Benlloch S, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Ghoussaini M, Luccarini C, Dennis J, Jugurnauth-Little S, Dadaev T, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock SJ, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB, Pharoah PD, Pashayan N, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle AB, Clements JA, Teixeira MR, Dicks E, Lee A, Dunning AM, Baynes C, Conroy D, Maranian MJ, Ahmed S, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As NJ, Woodhouse CJ, Thompson A, Dudderidge T, Ogden C, Cooper CS, Lophatananon A, Cox A, Southey MC, Hopper JL, English DR, Aly M, Adolfsson J, Xu J, Zheng SL, Yeager M, Kaaks R, Diver WR, Gaudet MM, Stern MC, Corral R, Joshi AD, Shahabi A, Wahlfors T, Tammela TL, Auvinen A, Virtamo J, Klarskov P, Nordestgaard BG, R?der MA, Nielsen SF, Bojesen SE, Siddiq A, Fitzgerald LM, Kolb S, Kwon EM, Karyadi DM, Blot WJ, Zheng W, Cai Q, McDonnell SK, Rinckleb AE, Drake B, Colditz G, Wokolorczyk D, Stephenson RA, Teerlink C, Muller H, Rothenbacher D, Sellers TA, Lin HY, Slavov C, Mitev V, Lose F, Srinivasan S, Maia S, Paulo P, Lange E, Cooney KA, Antoniou AC, Vincent D, Bacot F, Tessier DC, , , , , , Kote-Jarai Z, Easton DF
Nature genetics45(4)385-91, 391e1-2(2013 Apr)

Aberrant methylation and downregulation of sall3 in human hepatocellular carcinoma.
Yang XX, Sun JZ, Li FX, Wu YS, Du HY, Zhu W, Li XH, Li M
World journal of gastroenterology18(21)2719-26(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

sall3 shows aberrant methylation and downregulation in human hepatocellular carcinoma
Title: Aberrant methylation and downregulation of sall3 in human hepatocellular carcinoma.

Observational study of gene-disease association. (HuGE Navigator)
Title: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

This functional characterization of SALL3 sheds light on regulatory mechanisms for DNMT3A and provides new strategies to inhibit aberrant methylation in cancer.
Title: SALL3 interacts with DNMT3A and shows the ability to inhibit CpG island methylation in hepatocellular carcinoma.

Studies indicate that vertebrate sal orthologues (spalt-like/sall) have important developmental roles during neural development and organogenesis and gentic diseases.
Title: Regulation and function of Spalt proteins during animal development.

The following SALL3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SALL3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu20528	NM_171999.3 Latest version!	Homo sapiens spalt like transcription factor 3 (SALL3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SALL3 ( NM_171999.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_741996.2 Homo sapiens spalt like transcription factor 3 (SALL3), mRNA.

Price & Availability↑

CloneID	OHu20528
Clone ID Related Accession (Same CDS sequence)	NM_171999.3
Accession Version	NM_171999.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	sal-like protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC148296.2, AC099689.4, AI569735.1 and AW956238.1. This sequence is a reference standard in the RefSeqGene project. On Oct 14, 2011 this sequence version replaced NM_171999.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2151119, SAMEA2153427 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGTCTCGGC GCAAGCAGGC CAAGCCCCAG CACCTCAAGT CGGACGAGGA GCTGCTGCCG 
CCTGACGGGG CTCCCGAGCA CGCCGCCCCG GGGGAAGGTG CGGAGGACGC AGACAGCGGG 
CCCGAGAGCC GCAGCGGGGG CGAGGAGACC AGCGTGTGCG AGAAATGCTG CGCCGAGTTC 
TTCAAGTGGG CGGACTTCCT GGAGCACCAG CGGAGCTGCA CCAAGCTCCC GCCCGTGCTG 
ATCGTGCACG AGGACGCGCC CGCGCCGCCC CCCGAGGACT TCCCCGAGCC TTCGCCCGCC 
AGCTCCCCCA GCGAGCGCGC CGAAAGCGAG GCGGCCGAGG AGGCGGGTGC GGAGGGCGCG 
GAGGGCGAGG CCAGGCCGGT GGAGAAGGAG GCCGAGCCCA TGGACGCGGA ACCCGCGGGG 
GACACGCGCG CGCCCCGGCC CCCGCCTGCG GCCCCTGCAC CCCCAACGCC CGCCTACGGC 
GCGCCCAGCA CCAACGTGAC CCTGGAGGCG CTGCTGAGCA CCAAGGTGGC GGTGGCGCAG 
TTCTCGCAGG GCGCGCGCGC GGCAGGCGGC TCGGGAGCAG GTGGAGGCGT GGCAGCTGCA 
GCCGTGCCCC TGATCCTGGA ACAGCTCATG GCCCTGCAGC AGCAGCAGAT CCACCAGCTG 
CAGCTCATCG AGCAGATCCG CAGCCAGGTG GCCCTCATGC AGCGCCCGCC GCCGCGGCCC 
TCACTCAGCC CCGCGGCCGC CCCGAGCGCA CCGGGCCCGG CCCCCAGCCA GCTGCCCGGG 
CTGGCCGCGC TCCCGCTGTC GGCCGGGGCC CCTGCCGCCG CCATCGCGGG CTCGGGCCCC 
GCCGCCCCGG CCGCCTTCGA GGGCGCGCAG CCGCTGTCCC GGCCCGAGTC TGGCGCCAGC 
ACCCCCGGCG GCCCTGCGGA GCCCAGCGCG CCCGCCGCCC CCAGCGCCGC CCCTGCCCCC 
GCTGCCCCCG CCCCGGCGCC AGCGCCGCAG AGCGCAGCCT CGTCGCAGCC GCAGAGCGCA 
TCCACGCCGC CTGCCCTGGC CCCGGGGTCC CTGCTGGGTG CGGCGCCCGG CCTGCCAAGT 
CCGCTTCTAC CTCAGACTTC CGCCAGCGGC GTCATCTTCC CCAACCCGCT GGTCAGCATC 
GCGGCCACGG CCAACGCTCT GGACCCGCTG TCCGCGCTCA TGAAGCACCG CAAGGGCAAG 
CCGCCCAATG TGTCGGTGTT CGAGCCCAAA GCCAGCGCCG AGGACCCGTT CTTCAAGCAC 
AAATGCCGCT TCTGCGCCAA GGTCTTCGGC AGCGACAGCG CGCTCCAGAT CCACCTGCGC 
TCGCACACAG GCGAGCGGCC CTTCAAGTGC AACATCTGCG GGAACCGCTT CTCCACCAAA 
GGCAACCTGA AGGTGCACTT CCAGAGGCAC AAGGAGAAGT ACCCCCACAT CCAGATGAAC 
CCTTACCCGG TCCCCGAGTA CCTGGACAAC GTGCCCACCT GCTCGGGCAT CCCCTACGGC 
ATGTCGCTGC CCCCCGAGAA GCCCGTGACC ACCTGGCTGG ACAGCAAGCC CGTGCTGCCC 
ACCGTGCCCA CGTCCGTGGG GCTGCAACTG CCGCCCACTG TCCCTGGCGC GCACGGCTAC 
GCCGACTCTC CCAGCGCCAC CCCAGCCAGC CGCTCCCCGC AGAGGCCCTC GCCCGCCTCC 
AGCGAGTGCG CCTCCTTGTC CCCAGGCCTC AACCACGTGG AGTCCGGCGT GTCGGCCACC 
GCCGAGTCCC CACAGTCGCT CCTCGGCGGG CCGCCCCTCA CTAAAGCCGA GCCCGTCAGC 
CTGCCCTGCA CCAACGCCAG GGCCGGGGAC GCTCCCGTGG GCGCGCAGGC TAGCGCTGCA 
CCCACATCGG TGGACGGCGC ACCCACGAGC CTCGGCAGCC CCGGGCTGCC CGCCGTCTCC 
GAGCAGTTCA AGGCCCAGTT TCCGTTCGGG GGGCTGCTAG ACTCGATGCA AACGTCGGAA 
ACCTCGAAGC TGCAGCAGCT GGTGGAGAAC ATCGACAAGA AGATGACGGA CCCGAACCAG 
TGCGTCATCT GCCACCGGGT GCTGAGCTGC CAGAGCGCGC TGAAGATGCA CTACCGGACG 
CACACGGGGG AGCGGCCGTT CAAGTGCAAG ATCTGCGGCC GCGCCTTCAC CACCAAGGGC 
AACCTCAAGA CGCACTTCGG CGTGCACCGT GCAAAGCCGC CCCTGCGCGT GCAGCACTCC 
TGCCCCATCT GCCAGAAGAA GTTCACCAAC GCCGTGGTCC TGCAGCAGCA CATCCGCATG 
CACATGGGCG GCCAGATCCC CAACACGCCG CTGCCGGAGG GCTTCCAGGA TGCCATGGAC 
TCCGAGCTGG CCTACGACGA CAAGAACGCG GAGACCCTGA GCAGCTACGA TGACGACATG 
GACGAGAACT CCATGGAGGA CGACGCTGAG CTGAAGGACG CGGCCACCGA CCCGGCCAAG 
CCACTCCTGT CCTACGCGGG GTCCTGCCCG CCCTCCCCGC CCTCGGTCAT CTCCAGCATT 
GCCGCCCTGG AGAACCAGAT GAAGATGATC GACTCGGTCA TGAGCTGCCA GCAGCTGACC 
GGCCTCAAGT CCGTGGAGAA CGGGTCCGGG GAGAGTGACC GCCTGAGCAA CGACTCCTCG 
TCGGCCGTGG GCGACCTGGA GAGCCGCAGC GCGGGCAGCC CCGCCCTGTC CGAGTCCTCG 
TCCTCGCAGG CCCTGTCGCC GGCCCCCAGC AATGGTGAGA GCTTCCGCTC CAAGTCCCCG 
GGCCTGGGCG CCCCGGAGGA GCCCCAGGAA ATCCCGCTCA AGACCGAGAG GCCGGACAGC 
CCAGCCGCCG CCCCGGGCAG CGGAGGCGCC CCTGGCCGCG CGGGCATCAA GGAGGAGGCG 
CCCTTCAGCC TGCTGTTCCT GAGCAGGGAG CGGGGTAAGT GTCCCAGCAC TGTGTGTGGT 
GTCTGTGGCA AGCCTTTTGC TTGCAAGAGC GCGTTGGAAA TCCACTACCG CAGCCATACT 
AAGGAGCGGC CATTCGTCTG CGCGCTCTGC AGGCGAGGGT GCTCCACTAT GGGTAATTTA 
AAACAGCACT TACTGACACA CAGATTGAAA GAGCTGCCTT CTCAGTTATT TGACCCCAAC 
TTTGCTCTAG GTCCCAGCCA AAGCACTCCT AGCCTGATCT CCAGCGCCGC ACCCACCATG 
ATCAAAATGG AAGTGAACGG TCACGGCAAG GCCATGGCGC TGGGCGAGGG TCCCCCGCTG 
CCCGCGGGCG TCCAGGTCCC CGCCGGGCCT CAGACAGTGA TGGGCCCGGG CCTGGCGCCC 
ATGCTGGCCC CCCCACCGCG CCGGACGCCC AAGCAGCACA ACTGCCAGTC GTGCGGGAAG 
ACCTTCTCCT CGGCCAGCGC CCTGCAGATC CATGAGCGCA CGCACACCGG CGAGAAGCCG 
TTCGGCTGCA CCATCTGCGG CCGGGCCTTC ACCACTAAGG GCAACCTCAA GGTGCACATG 
GGGACACACA TGTGGAATAA CGCCCCCGCG AGACGCGGCC GCCGCCTGTC TGTGGAGAAC 
CCCATGGCTC TCCTAGGGGG TGATGCCCTG AAGTTCTCTG AAATGTTCCA GAAGGACCTG 
GCAGCTCGGG CAATGAACGT CGACCCCAGT TTTTGGAACC AGTATGCTGC AGCCATCACT 
AACGGGCTCG CCATGAAGAA CAACGAGATC TCCGTCATCC AGAACGGCGG CATCCCCCAG 
CTCCCCGTGA GTCTTGGGGG CAGCGCCCTC CCCCCTCTGG GCAGCATGGC CAGTGGGATG 
GACAAAGCAC GCACTGGCAG TAGCCCACCC ATCGTCAGCT TGGACAAAGC GAGCTCAGAA 
ACAGCAGCCA GCCGCCCATT CACGCGGTTT ATCGAGGATA ACAAGGAGAT TGGTATCAAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_741996.2
CDS	1..3903
Translation	MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMDSELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIAALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDLAARAMNVDPSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGSALPPLGSMASGMDKARTGSSPPIVSLDKASSETAASRPFTRFIEDNKEIGIN

Target ORF information:

RefSeq Version	NM_171999.3
Organism	Homo sapiens(human)
Definition	Homo sapiens spalt like transcription factor 3 (SALL3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_171999.3

ORF Insert Sequence:

ATGTCTCGGC GCAAGCAGGC CAAGCCCCAG CACCTCAAGT CGGACGAGGA GCTGCTGCCG 
CCTGACGGGG CTCCCGAGCA CGCCGCCCCG GGGGAAGGTG CGGAGGACGC AGACAGCGGG 
CCCGAGAGCC GCAGCGGGGG CGAGGAGACC AGCGTGTGCG AGAAATGCTG CGCCGAGTTC 
TTCAAGTGGG CGGACTTCCT GGAGCACCAG CGGAGCTGCA CCAAGCTCCC GCCCGTGCTG 
ATCGTGCACG AGGACGCGCC CGCGCCGCCC CCCGAGGACT TCCCCGAGCC TTCGCCCGCC 
AGCTCCCCCA GCGAGCGCGC CGAAAGCGAG GCGGCCGAGG AGGCGGGTGC GGAGGGCGCG 
GAGGGCGAGG CCAGGCCGGT GGAGAAGGAG GCCGAGCCCA TGGACGCGGA ACCCGCGGGG 
GACACGCGCG CGCCCCGGCC CCCGCCTGCG GCCCCTGCAC CCCCAACGCC CGCCTACGGC 
GCGCCCAGCA CCAACGTGAC CCTGGAGGCG CTGCTGAGCA CCAAGGTGGC GGTGGCGCAG 
TTCTCGCAGG GCGCGCGCGC GGCAGGCGGC TCGGGAGCAG GTGGAGGCGT GGCAGCTGCA 
GCCGTGCCCC TGATCCTGGA ACAGCTCATG GCCCTGCAGC AGCAGCAGAT CCACCAGCTG 
CAGCTCATCG AGCAGATCCG CAGCCAGGTG GCCCTCATGC AGCGCCCGCC GCCGCGGCCC 
TCACTCAGCC CCGCGGCCGC CCCGAGCGCA CCGGGCCCGG CCCCCAGCCA GCTGCCCGGG 
CTGGCCGCGC TCCCGCTGTC GGCCGGGGCC CCTGCCGCCG CCATCGCGGG CTCGGGCCCC 
GCCGCCCCGG CCGCCTTCGA GGGCGCGCAG CCGCTGTCCC GGCCCGAGTC TGGCGCCAGC 
ACCCCCGGCG GCCCTGCGGA GCCCAGCGCG CCCGCCGCCC CCAGCGCCGC CCCTGCCCCC 
GCTGCCCCCG CCCCGGCGCC AGCGCCGCAG AGCGCAGCCT CGTCGCAGCC GCAGAGCGCA 
TCCACGCCGC CTGCCCTGGC CCCGGGGTCC CTGCTGGGTG CGGCGCCCGG CCTGCCAAGT 
CCGCTTCTAC CTCAGACTTC CGCCAGCGGC GTCATCTTCC CCAACCCGCT GGTCAGCATC 
GCGGCCACGG CCAACGCTCT GGACCCGCTG TCCGCGCTCA TGAAGCACCG CAAGGGCAAG 
CCGCCCAATG TGTCGGTGTT CGAGCCCAAA GCCAGCGCCG AGGACCCGTT CTTCAAGCAC 
AAATGCCGCT TCTGCGCCAA GGTCTTCGGC AGCGACAGCG CGCTCCAGAT CCACCTGCGC 
TCGCACACAG GCGAGCGGCC CTTCAAGTGC AACATCTGCG GGAACCGCTT CTCCACCAAA 
GGCAACCTGA AGGTGCACTT CCAGAGGCAC AAGGAGAAGT ACCCCCACAT CCAGATGAAC 
CCTTACCCGG TCCCCGAGTA CCTGGACAAC GTGCCCACCT GCTCGGGCAT CCCCTACGGC 
ATGTCGCTGC CCCCCGAGAA GCCCGTGACC ACCTGGCTGG ACAGCAAGCC CGTGCTGCCC 
ACCGTGCCCA CGTCCGTGGG GCTGCAACTG CCGCCCACTG TCCCTGGCGC GCACGGCTAC 
GCCGACTCTC CCAGCGCCAC CCCAGCCAGC CGCTCCCCGC AGAGGCCCTC GCCCGCCTCC 
AGCGAGTGCG CCTCCTTGTC CCCAGGCCTC AACCACGTGG AGTCCGGCGT GTCGGCCACC 
GCCGAGTCCC CACAGTCGCT CCTCGGCGGG CCGCCCCTCA CTAAAGCCGA GCCCGTCAGC 
CTGCCCTGCA CCAACGCCAG GGCCGGGGAC GCTCCCGTGG GCGCGCAGGC TAGCGCTGCA 
CCCACATCGG TGGACGGCGC ACCCACGAGC CTCGGCAGCC CCGGGCTGCC CGCCGTCTCC 
GAGCAGTTCA AGGCCCAGTT TCCGTTCGGG GGGCTGCTAG ACTCGATGCA AACGTCGGAA 
ACCTCGAAGC TGCAGCAGCT GGTGGAGAAC ATCGACAAGA AGATGACGGA CCCGAACCAG 
TGCGTCATCT GCCACCGGGT GCTGAGCTGC CAGAGCGCGC TGAAGATGCA CTACCGGACG 
CACACGGGGG AGCGGCCGTT CAAGTGCAAG ATCTGCGGCC GCGCCTTCAC CACCAAGGGC 
AACCTCAAGA CGCACTTCGG CGTGCACCGT GCAAAGCCGC CCCTGCGCGT GCAGCACTCC 
TGCCCCATCT GCCAGAAGAA GTTCACCAAC GCCGTGGTCC TGCAGCAGCA CATCCGCATG 
CACATGGGCG GCCAGATCCC CAACACGCCG CTGCCGGAGG GCTTCCAGGA TGCCATGGAC 
TCCGAGCTGG CCTACGACGA CAAGAACGCG GAGACCCTGA GCAGCTACGA TGACGACATG 
GACGAGAACT CCATGGAGGA CGACGCTGAG CTGAAGGACG CGGCCACCGA CCCGGCCAAG 
CCACTCCTGT CCTACGCGGG GTCCTGCCCG CCCTCCCCGC CCTCGGTCAT CTCCAGCATT 
GCCGCCCTGG AGAACCAGAT GAAGATGATC GACTCGGTCA TGAGCTGCCA GCAGCTGACC 
GGCCTCAAGT CCGTGGAGAA CGGGTCCGGG GAGAGTGACC GCCTGAGCAA CGACTCCTCG 
TCGGCCGTGG GCGACCTGGA GAGCCGCAGC GCGGGCAGCC CCGCCCTGTC CGAGTCCTCG 
TCCTCGCAGG CCCTGTCGCC GGCCCCCAGC AATGGTGAGA GCTTCCGCTC CAAGTCCCCG 
GGCCTGGGCG CCCCGGAGGA GCCCCAGGAA ATCCCGCTCA AGACCGAGAG GCCGGACAGC 
CCAGCCGCCG CCCCGGGCAG CGGAGGCGCC CCTGGCCGCG CGGGCATCAA GGAGGAGGCG 
CCCTTCAGCC TGCTGTTCCT GAGCAGGGAG CGGGGTAAGT GTCCCAGCAC TGTGTGTGGT 
GTCTGTGGCA AGCCTTTTGC TTGCAAGAGC GCGTTGGAAA TCCACTACCG CAGCCATACT 
AAGGAGCGGC CATTCGTCTG CGCGCTCTGC AGGCGAGGGT GCTCCACTAT GGGTAATTTA 
AAACAGCACT TACTGACACA CAGATTGAAA GAGCTGCCTT CTCAGTTATT TGACCCCAAC 
TTTGCTCTAG GTCCCAGCCA AAGCACTCCT AGCCTGATCT CCAGCGCCGC ACCCACCATG 
ATCAAAATGG AAGTGAACGG TCACGGCAAG GCCATGGCGC TGGGCGAGGG TCCCCCGCTG 
CCCGCGGGCG TCCAGGTCCC CGCCGGGCCT CAGACAGTGA TGGGCCCGGG CCTGGCGCCC 
ATGCTGGCCC CCCCACCGCG CCGGACGCCC AAGCAGCACA ACTGCCAGTC GTGCGGGAAG 
ACCTTCTCCT CGGCCAGCGC CCTGCAGATC CATGAGCGCA CGCACACCGG CGAGAAGCCG 
TTCGGCTGCA CCATCTGCGG CCGGGCCTTC ACCACTAAGG GCAACCTCAA GGTGCACATG 
GGGACACACA TGTGGAATAA CGCCCCCGCG AGACGCGGCC GCCGCCTGTC TGTGGAGAAC 
CCCATGGCTC TCCTAGGGGG TGATGCCCTG AAGTTCTCTG AAATGTTCCA GAAGGACCTG 
GCAGCTCGGG CAATGAACGT CGACCCCAGT TTTTGGAACC AGTATGCTGC AGCCATCACT 
AACGGGCTCG CCATGAAGAA CAACGAGATC TCCGTCATCC AGAACGGCGG CATCCCCCAG 
CTCCCCGTGA GTCTTGGGGG CAGCGCCCTC CCCCCTCTGG GCAGCATGGC CAGTGGGATG 
GACAAAGCAC GCACTGGCAG TAGCCCACCC ATCGTCAGCT TGGACAAAGC GAGCTCAGAA 
ACAGCAGCCA GCCGCCCATT CACGCGGTTT ATCGAGGATA ACAAGGAGAT TGGTATCAAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Epigenetic silencing of
Clinical epigenetics964(2017)
Misawa K,Mochizuki D,Imai A,Misawa Y,Endo S,Mima M,Kawasaki H,Carey TE,Kanazawa T

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
Nature genetics45(4)385-91, 391e1-2(2013 Apr)
Eeles RA,Olama AA,Benlloch S,Saunders EJ,Leongamornlert DA,Tymrakiewicz M,Ghoussaini M,Luccarini C,Dennis J,Jugurnauth-Little S,Dadaev T,Neal DE,Hamdy FC,Donovan JL,Muir K,Giles GG,Severi G,Wiklund F,Gronberg H,Haiman CA,Schumacher F,Henderson BE,Le Marchand L,Lindstrom S,Kraft P,Hunter DJ,Gapstur S,Chanock SJ,Berndt SI,Albanes D,Andriole G,Schleutker J,Weischer M,Canzian F,Riboli E,Key TJ,Travis RC,Campa D,Ingles SA,John EM,Hayes RB,Pharoah PD,Pashayan N,Khaw KT,Stanford JL,Ostrander EA,Signorello LB,Thibodeau SN,Schaid D,Maier C,Vogel W,Kibel AS,Cybulski C,Lubinski J,Cannon-Albright L,Brenner H,Park JY,Kaneva R,Batra J,Spurdle AB,Clements JA,Teixeira MR,Dicks E,Lee A,Dunning AM,Baynes C,Conroy D,Maranian MJ,Ahmed S,Govindasami K,Guy M,Wilkinson RA,Sawyer EJ,Morgan A,Dearnaley DP,Horwich A,Huddart RA,Khoo VS,Parker CC,Van As NJ,Woodhouse CJ,Thompson A,Dudderidge T,Ogden C,Cooper CS,Lophatananon A,Cox A,Southey MC,Hopper JL,English DR,Aly M,Adolfsson J,Xu J,Zheng SL,Yeager M,Kaaks R,Diver WR,Gaudet MM,Stern MC,Corral R,Joshi AD,Shahabi A,Wahlfors T,Tammela TL,Auvinen A,Virtamo J,Klarskov P,Nordestgaard BG,R?der MA,Nielsen SF,Bojesen SE,Siddiq A,Fitzgerald LM,Kolb S,Kwon EM,Karyadi DM,Blot WJ,Zheng W,Cai Q,McDonnell SK,Rinckleb AE,Drake B,Colditz G,Wokolorczyk D,Stephenson RA,Teerlink C,Muller H,Rothenbacher D,Sellers TA,Lin HY,Slavov C,Mitev V,Lose F,Srinivasan S,Maia S,Paulo P,Lange E,Cooney KA,Antoniou AC,Vincent D,Bacot F,Tessier DC,,,,,,Kote-Jarai Z,Easton DF

Aberrant methylation and downregulation of sall3 in human hepatocellular carcinoma.
World journal of gastroenterology18(21)2719-26(2012 Jun)
Yang XX,Sun JZ,Li FX,Wu YS,Du HY,Zhu W,Li XH,Li M

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SALL3 cDNA ORF clone, Homo sapiens(human)

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