The following IFIT5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IFIT5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu09662 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_012420.2 , NM_012420.3 | |
| Accession Version | NM_012420.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-12-26 | |
| Organism | Homo sapiens(human) | |
| Product | interferon-induced protein with tetratricopeptide repeats 5 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC392439.1 and AL353146.9. On Aug 26, 2008 this sequence version replaced NM_012420.1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BP264380.1, SRR1803611.8290.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAGTGAAA TTCGTAAGGA CACCTTGAAG GCCATTCTGT TGGAGTTAGA ATGTCATTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_036552.1 |
| CDS | 232..1680 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_012420.2 |
1 | ATGAGTGAAA TTCGTAAGGA CACCTTGAAG GCCATTCTGT TGGAGTTAGA ATGTCATTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu09662 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_012420.2 , NM_012420.3 | |
| Accession Version | NM_012420.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-30 | |
| Organism | Homo sapiens(human) | |
| Product | interferon-induced protein with tetratricopeptide repeats 5 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC392439.1 and AL353146.9. On Nov 22, 2018 this sequence version replaced NM_012420.2. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BP264380.1, SRR1803611.8290.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000371795.5/ ENSP00000360860.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGAGTGAAA TTCGTAAGGA CACCTTGAAG GCCATTCTGT TGGAGTTAGA ATGTCATTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_036552.1 |
| CDS | 232..1680 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_012420.3 |
1 | ATGAGTGAAA TTCGTAAGGA CACCTTGAAG GCCATTCTGT TGGAGTTAGA ATGTCATTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
IFIT5 positively regulates NF-?B signaling through synergizing the recruitment of I?B kinase (IKK) to TGF-?-activated kinase 1 (TAK1). |
Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5. |
The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins. |
Crystal structure and nucleotide selectivity of human IFIT5/ISG58. |
Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins. |
