Gene Symbol | ZFPM2 |
Entrez Gene ID | 23414 |
Full Name | zinc finger protein, FOG family member 2 |
Synonyms | DIH3,FOG2,SRXY9,ZC2HC11B,ZNF89B,hFOG-2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Tetralogy of Fallot, 187500 (3); Diaphragmatic hernia 3, 610187 (3); 46XY sex reversal 9, 616067 (3) |