CD93 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CD93
Entrez Gene ID	22918
Full Name	CD93 molecule
Synonyms	C1QR1,C1qR(P),C1qRP,CDw93,ECSM3,MXRA4,dJ737E23.1
General protein information	Preferred Names CD93 molecule Names complement component C1q receptor C1q receptor 1 C1q/MBL/SPA receptor C1qR CD93 antigen complement component 1 q subcomponent receptor 1 matrix-remodeling-associated protein 4 matrix-remodelling associated 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20p11.21
Summary	The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq, Jul 2008].
Disorder MIM:	120577

mRNA and Protein(s)

mRNA	Protein	Name
NM_012072.3	NP_036204.2	complement component C1q receptor precursor
NM_012072.4	NP_036204.2	complement component C1q receptor precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CD93	XP_848496.1
Gallus gallus (chicken)	CD93	NP_001186380.1
Rattus norvegicus (Norway rat)	Cd93	NP_445835.1
Homo sapiens (human)	CD93	NP_036204.2
	CD93	XP_001095530.2
Mus musculus (house mouse)	Cd93	NP_034870.1
Danio rerio (zebrafish)	LOC101882826	XP_005159016.1
Pan troglodytes (chimpanzee)	CD93	XP_514549.2
Bos taurus (cattle)	CD93	XP_003586832.1
Xenopus tropicalis (tropical clawed frog)	cd93	XP_002936962.2

Gene Ontology
Bibliography

Related articles in PubMed

Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium.
Galvagni F, Nardi F, Spiga O, Trezza A, Tarticchio G, Pellicani R, Andreuzzi E, Caldi E, Toti P, Tosi GM, Santucci A, Iozzo RV, Mongiat M, Orlandini M
Matrix biology : journal of the International Society for Matrix Biology64112-127(2017 Dec)

Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface.
Khan KA, Naylor AJ, Khan A, Noy PJ, Mambretti M, Lodhia P, Athwal J, Korzystka A, Buckley CD, Willcox BE, Mohammed F, Bicknell R
Oncogene36(44)6097-6108(2017 Nov)

Psoriasis and Pro-angiogenetic Factor CD93: Gene Expression and Association with Gene Polymorphism Suggests a Role in Disease Pathogenesis.
Duvetorp A, Slind Olsen R, Skarstedt M, S?derman J, Seifert O
Acta dermato-venereologica97(8)916-921(2017 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings identify novel protein interactions involving CLEC14A, CD93 and CD248 with MMRN2 as targetable components of vessel formation
Title: Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface.

both transmembrane and soluble CD93 are overexpressed in patients with neovascular Age-Related Macular Degeneration.
Title: CD93 as a Potential Target in Neovascular Age-Related Macular Degeneration.

Elevated serum sCD93 levels reflected exacerbated status of allergic diseases, including CSU [chronic spontaneous urticaria ], AR[allergic rhinitis], and asthma. ICS [inhaled corticosteroid] use significantly diminished serum sCD93 levels in steroid-naive patients with BA[Bronchial asthma]. This result may suggest sCD93 in serum as a therapeutic marker for allergic inflammation.
Title: Soluble CD93 in Serum as a Marker of Allergic Inflammation.

Soluble expression of disulfide-bonded C-type lectin like domain of human CD93 in the cytoplasm of Escherichia coli. The recombinant protein could alter LPS pro-inflammatory activity on THP1 cells.
Title: Soluble expression of disulfide-bonded C-type lectin like domain of human CD93 in the cytoplasm of Escherichia coli.

CD93 and Other Plasma Cell Survival Factor Genes Associated with Measles-Specific Antibody Response after Vaccination
Title: Whole Transcriptome Profiling Identifies CD93 and Other Plasma Cell Survival Factor Genes Associated with Measles-Specific Antibody Response after Vaccination.

The following CD93 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CD93 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13877	NM_012072.4 Latest version!	Homo sapiens CD93 molecule (CD93), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu13877	NM_012072.3	Homo sapiens CD93 molecule (CD93), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CD93 ( NM_012072.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036204.2 Homo sapiens CD93 molecule (CD93), mRNA.

Price & Availability↑

CloneID	OHu13877
Clone ID Related Accession (Same CDS sequence)	NM_012072.3 , NM_012072.4
Accession Version	NM_012072.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1959bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	complement component C1q receptor precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U94333.1, BC028075.1 and AL118508.27. On Feb 23, 2006 this sequence version replaced NM_012072.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U94333.1, SRR1660809.198432.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2153307 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCACCT CCATGGGCCT GCTGCTGCTG CTGCTGCTGC TCCTGACCCA GCCCGGGGCG 
GGGACGGGAG CTGACACGGA GGCGGTGGTC TGCGTGGGGA CCGCCTGCTA CACGGCCCAC 
TCGGGCAAGC TGAGCGCTGC CGAGGCCCAG AACCACTGCA ACCAGAACGG GGGCAACCTG 
GCCACTGTGA AGAGCAAGGA GGAGGCCCAG CACGTCCAGC GAGTACTGGC CCAGCTCCTG 
AGGCGGGAGG CAGCCCTGAC GGCGAGGATG AGCAAGTTCT GGATTGGGCT CCAGCGAGAG 
AAGGGCAAGT GCCTGGACCC TAGTCTGCCG CTGAAGGGCT TCAGCTGGGT GGGCGGGGGG 
GAGGACACGC CTTACTCTAA CTGGCACAAG GAGCTCCGGA ACTCGTGCAT CTCCAAGCGC 
TGTGTGTCTC TGCTGCTGGA CCTGTCCCAG CCGCTCCTTC CCAGCCGCCT CCCCAAGTGG 
TCTGAGGGCC CCTGTGGGAG CCCAGGCTCC CCCGGAAGTA ACATTGAGGG CTTCGTGTGC 
AAGTTCAGCT TCAAAGGCAT GTGCCGGCCT CTGGCCCTGG GGGGCCCAGG TCAGGTGACC 
TACACCACCC CCTTCCAGAC CACCAGTTCC TCCTTGGAGG CTGTGCCCTT TGCCTCTGCG 
GCCAATGTAG CCTGTGGGGA AGGTGACAAG GACGAGACTC AGAGTCATTA TTTCCTGTGC 
AAGGAGAAGG CCCCCGATGT GTTCGACTGG GGCAGCTCGG GCCCCCTCTG TGTCAGCCCC 
AAGTATGGCT GCAACTTCAA CAATGGGGGC TGCCACCAGG ACTGCTTTGA AGGGGGGGAT 
GGCTCCTTCC TCTGCGGCTG CCGACCAGGA TTCCGGCTGC TGGATGACCT GGTGACCTGT 
GCCTCTCGAA ACCCTTGCAG CTCCAGCCCA TGTCGTGGGG GGGCCACGTG CGTCCTGGGA 
CCCCATGGGA AAAACTACAC GTGCCGCTGC CCCCAAGGGT ACCAGCTGGA CTCGAGTCAG 
CTGGACTGTG TGGACGTGGA TGAATGCCAG GACTCCCCCT GTGCCCAGGA GTGTGTCAAC 
ACCCCTGGGG GCTTCCGCTG CGAATGCTGG GTTGGCTATG AGCCGGGCGG TCCTGGAGAG 
GGGGCCTGTC AGGATGTGGA TGAGTGTGCT CTGGGTCGCT CGCCTTGCGC CCAGGGCTGC 
ACCAACACAG ATGGCTCATT TCACTGCTCC TGTGAGGAGG GCTACGTCCT GGCCGGGGAG 
GACGGGACTC AGTGCCAGGA CGTGGATGAG TGTGTGGGCC CGGGGGGCCC CCTCTGCGAC 
AGCTTGTGCT TCAACACACA AGGGTCCTTC CACTGTGGCT GCCTGCCAGG CTGGGTGCTG 
GCCCCAAATG GGGTCTCTTG CACCATGGGG CCTGTGTCTC TGGGACCACC ATCTGGGCCC 
CCCGATGAGG AGGACAAAGG AGAGAAAGAA GGGAGCACCG TGCCCCGTGC TGCAACAGCC 
AGTCCCACAA GGGGCCCCGA GGGCACCCCC AAGGCTACAC CCACCACAAG TAGACCTTCG 
CTGTCATCTG ACGCCCCCAT CACATCTGCC CCACTCAAGA TGCTGGCCCC CAGTGGGTCC 
CCAGGCGTCT GGAGGGAGCC CAGCATCCAT CACGCCACAG CTGCCTCTGG CCCCCAGGAG 
CCTGCAGGTG GGGACTCCTC CGTGGCCACA CAAAACAACG ATGGCACTGA CGGGCAAAAG 
CTGCTTTTAT TCTACATCCT AGGCACCGTG GTGGCCATCC TACTCCTGCT GGCCCTGGCT 
CTGGGGCTAC TGGTCTATCG CAAGCGGAGA GCGAAGAGGG AGGAGAAGAA GGAGAAGAAG 
CCCCAGAATG CGGCAGACAG TTACTCCTGG GTTCCAGAGC GAGCTGAGAG CAGGGCCATG 
GAGAACCAGT ACAGTCCGAC ACCTGGGACA GACTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036204.2
CDS	149..2107
Translation	MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNLATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGGEDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALALGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC

Target ORF information:

RefSeq Version	NM_012072.3
Organism	Homo sapiens(human)
Definition	Homo sapiens CD93 molecule (CD93), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012072.3

ORF Insert Sequence:

ATGGCCACCT CCATGGGCCT GCTGCTGCTG CTGCTGCTGC TCCTGACCCA GCCCGGGGCG 
GGGACGGGAG CTGACACGGA GGCGGTGGTC TGCGTGGGGA CCGCCTGCTA CACGGCCCAC 
TCGGGCAAGC TGAGCGCTGC CGAGGCCCAG AACCACTGCA ACCAGAACGG GGGCAACCTG 
GCCACTGTGA AGAGCAAGGA GGAGGCCCAG CACGTCCAGC GAGTACTGGC CCAGCTCCTG 
AGGCGGGAGG CAGCCCTGAC GGCGAGGATG AGCAAGTTCT GGATTGGGCT CCAGCGAGAG 
AAGGGCAAGT GCCTGGACCC TAGTCTGCCG CTGAAGGGCT TCAGCTGGGT GGGCGGGGGG 
GAGGACACGC CTTACTCTAA CTGGCACAAG GAGCTCCGGA ACTCGTGCAT CTCCAAGCGC 
TGTGTGTCTC TGCTGCTGGA CCTGTCCCAG CCGCTCCTTC CCAGCCGCCT CCCCAAGTGG 
TCTGAGGGCC CCTGTGGGAG CCCAGGCTCC CCCGGAAGTA ACATTGAGGG CTTCGTGTGC 
AAGTTCAGCT TCAAAGGCAT GTGCCGGCCT CTGGCCCTGG GGGGCCCAGG TCAGGTGACC 
TACACCACCC CCTTCCAGAC CACCAGTTCC TCCTTGGAGG CTGTGCCCTT TGCCTCTGCG 
GCCAATGTAG CCTGTGGGGA AGGTGACAAG GACGAGACTC AGAGTCATTA TTTCCTGTGC 
AAGGAGAAGG CCCCCGATGT GTTCGACTGG GGCAGCTCGG GCCCCCTCTG TGTCAGCCCC 
AAGTATGGCT GCAACTTCAA CAATGGGGGC TGCCACCAGG ACTGCTTTGA AGGGGGGGAT 
GGCTCCTTCC TCTGCGGCTG CCGACCAGGA TTCCGGCTGC TGGATGACCT GGTGACCTGT 
GCCTCTCGAA ACCCTTGCAG CTCCAGCCCA TGTCGTGGGG GGGCCACGTG CGTCCTGGGA 
CCCCATGGGA AAAACTACAC GTGCCGCTGC CCCCAAGGGT ACCAGCTGGA CTCGAGTCAG 
CTGGACTGTG TGGACGTGGA TGAATGCCAG GACTCCCCCT GTGCCCAGGA GTGTGTCAAC 
ACCCCTGGGG GCTTCCGCTG CGAATGCTGG GTTGGCTATG AGCCGGGCGG TCCTGGAGAG 
GGGGCCTGTC AGGATGTGGA TGAGTGTGCT CTGGGTCGCT CGCCTTGCGC CCAGGGCTGC 
ACCAACACAG ATGGCTCATT TCACTGCTCC TGTGAGGAGG GCTACGTCCT GGCCGGGGAG 
GACGGGACTC AGTGCCAGGA CGTGGATGAG TGTGTGGGCC CGGGGGGCCC CCTCTGCGAC 
AGCTTGTGCT TCAACACACA AGGGTCCTTC CACTGTGGCT GCCTGCCAGG CTGGGTGCTG 
GCCCCAAATG GGGTCTCTTG CACCATGGGG CCTGTGTCTC TGGGACCACC ATCTGGGCCC 
CCCGATGAGG AGGACAAAGG AGAGAAAGAA GGGAGCACCG TGCCCCGTGC TGCAACAGCC 
AGTCCCACAA GGGGCCCCGA GGGCACCCCC AAGGCTACAC CCACCACAAG TAGACCTTCG 
CTGTCATCTG ACGCCCCCAT CACATCTGCC CCACTCAAGA TGCTGGCCCC CAGTGGGTCC 
CCAGGCGTCT GGAGGGAGCC CAGCATCCAT CACGCCACAG CTGCCTCTGG CCCCCAGGAG 
CCTGCAGGTG GGGACTCCTC CGTGGCCACA CAAAACAACG ATGGCACTGA CGGGCAAAAG 
CTGCTTTTAT TCTACATCCT AGGCACCGTG GTGGCCATCC TACTCCTGCT GGCCCTGGCT 
CTGGGGCTAC TGGTCTATCG CAAGCGGAGA GCGAAGAGGG AGGAGAAGAA GGAGAAGAAG 
CCCCAGAATG CGGCAGACAG TTACTCCTGG GTTCCAGAGC GAGCTGAGAG CAGGGCCATG 
GAGAACCAGT ACAGTCCGAC ACCTGGGACA GACTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD93 ( NM_012072.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_036204.2 Homo sapiens CD93 molecule (CD93), mRNA.

Price & Availability↑

CloneID	OHu13877
Clone ID Related Accession (Same CDS sequence)	NM_012072.3 , NM_012072.4
Accession Version	NM_012072.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1959bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	complement component C1q receptor precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U94333.1, BC028075.1 and AL118508.27. On Nov 23, 2018 this sequence version replaced NM_012072.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.198432.1, AB209895.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2153307 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000246006.5/ ENSP00000246006.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCACCT CCATGGGCCT GCTGCTGCTG CTGCTGCTGC TCCTGACCCA GCCCGGGGCG 
GGGACGGGAG CTGACACGGA GGCGGTGGTC TGCGTGGGGA CCGCCTGCTA CACGGCCCAC 
TCGGGCAAGC TGAGCGCTGC CGAGGCCCAG AACCACTGCA ACCAGAACGG GGGCAACCTG 
GCCACTGTGA AGAGCAAGGA GGAGGCCCAG CACGTCCAGC GAGTACTGGC CCAGCTCCTG 
AGGCGGGAGG CAGCCCTGAC GGCGAGGATG AGCAAGTTCT GGATTGGGCT CCAGCGAGAG 
AAGGGCAAGT GCCTGGACCC TAGTCTGCCG CTGAAGGGCT TCAGCTGGGT GGGCGGGGGG 
GAGGACACGC CTTACTCTAA CTGGCACAAG GAGCTCCGGA ACTCGTGCAT CTCCAAGCGC 
TGTGTGTCTC TGCTGCTGGA CCTGTCCCAG CCGCTCCTTC CCAGCCGCCT CCCCAAGTGG 
TCTGAGGGCC CCTGTGGGAG CCCAGGCTCC CCCGGAAGTA ACATTGAGGG CTTCGTGTGC 
AAGTTCAGCT TCAAAGGCAT GTGCCGGCCT CTGGCCCTGG GGGGCCCAGG TCAGGTGACC 
TACACCACCC CCTTCCAGAC CACCAGTTCC TCCTTGGAGG CTGTGCCCTT TGCCTCTGCG 
GCCAATGTAG CCTGTGGGGA AGGTGACAAG GACGAGACTC AGAGTCATTA TTTCCTGTGC 
AAGGAGAAGG CCCCCGATGT GTTCGACTGG GGCAGCTCGG GCCCCCTCTG TGTCAGCCCC 
AAGTATGGCT GCAACTTCAA CAATGGGGGC TGCCACCAGG ACTGCTTTGA AGGGGGGGAT 
GGCTCCTTCC TCTGCGGCTG CCGACCAGGA TTCCGGCTGC TGGATGACCT GGTGACCTGT 
GCCTCTCGAA ACCCTTGCAG CTCCAGCCCA TGTCGTGGGG GGGCCACGTG CGTCCTGGGA 
CCCCATGGGA AAAACTACAC GTGCCGCTGC CCCCAAGGGT ACCAGCTGGA CTCGAGTCAG 
CTGGACTGTG TGGACGTGGA TGAATGCCAG GACTCCCCCT GTGCCCAGGA GTGTGTCAAC 
ACCCCTGGGG GCTTCCGCTG CGAATGCTGG GTTGGCTATG AGCCGGGCGG TCCTGGAGAG 
GGGGCCTGTC AGGATGTGGA TGAGTGTGCT CTGGGTCGCT CGCCTTGCGC CCAGGGCTGC 
ACCAACACAG ATGGCTCATT TCACTGCTCC TGTGAGGAGG GCTACGTCCT GGCCGGGGAG 
GACGGGACTC AGTGCCAGGA CGTGGATGAG TGTGTGGGCC CGGGGGGCCC CCTCTGCGAC 
AGCTTGTGCT TCAACACACA AGGGTCCTTC CACTGTGGCT GCCTGCCAGG CTGGGTGCTG 
GCCCCAAATG GGGTCTCTTG CACCATGGGG CCTGTGTCTC TGGGACCACC ATCTGGGCCC 
CCCGATGAGG AGGACAAAGG AGAGAAAGAA GGGAGCACCG TGCCCCGTGC TGCAACAGCC 
AGTCCCACAA GGGGCCCCGA GGGCACCCCC AAGGCTACAC CCACCACAAG TAGACCTTCG 
CTGTCATCTG ACGCCCCCAT CACATCTGCC CCACTCAAGA TGCTGGCCCC CAGTGGGTCC 
CCAGGCGTCT GGAGGGAGCC CAGCATCCAT CACGCCACAG CTGCCTCTGG CCCCCAGGAG 
CCTGCAGGTG GGGACTCCTC CGTGGCCACA CAAAACAACG ATGGCACTGA CGGGCAAAAG 
CTGCTTTTAT TCTACATCCT AGGCACCGTG GTGGCCATCC TACTCCTGCT GGCCCTGGCT 
CTGGGGCTAC TGGTCTATCG CAAGCGGAGA GCGAAGAGGG AGGAGAAGAA GGAGAAGAAG 
CCCCAGAATG CGGCAGACAG TTACTCCTGG GTTCCAGAGC GAGCTGAGAG CAGGGCCATG 
GAGAACCAGT ACAGTCCGAC ACCTGGGACA GACTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036204.2
CDS	133..2091
Translation	MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNLATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGGEDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALALGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC

Target ORF information:

RefSeq Version	NM_012072.4
Organism	Homo sapiens(human)
Definition	Homo sapiens CD93 molecule (CD93), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012072.4

ORF Insert Sequence:

ATGGCCACCT CCATGGGCCT GCTGCTGCTG CTGCTGCTGC TCCTGACCCA GCCCGGGGCG 
GGGACGGGAG CTGACACGGA GGCGGTGGTC TGCGTGGGGA CCGCCTGCTA CACGGCCCAC 
TCGGGCAAGC TGAGCGCTGC CGAGGCCCAG AACCACTGCA ACCAGAACGG GGGCAACCTG 
GCCACTGTGA AGAGCAAGGA GGAGGCCCAG CACGTCCAGC GAGTACTGGC CCAGCTCCTG 
AGGCGGGAGG CAGCCCTGAC GGCGAGGATG AGCAAGTTCT GGATTGGGCT CCAGCGAGAG 
AAGGGCAAGT GCCTGGACCC TAGTCTGCCG CTGAAGGGCT TCAGCTGGGT GGGCGGGGGG 
GAGGACACGC CTTACTCTAA CTGGCACAAG GAGCTCCGGA ACTCGTGCAT CTCCAAGCGC 
TGTGTGTCTC TGCTGCTGGA CCTGTCCCAG CCGCTCCTTC CCAGCCGCCT CCCCAAGTGG 
TCTGAGGGCC CCTGTGGGAG CCCAGGCTCC CCCGGAAGTA ACATTGAGGG CTTCGTGTGC 
AAGTTCAGCT TCAAAGGCAT GTGCCGGCCT CTGGCCCTGG GGGGCCCAGG TCAGGTGACC 
TACACCACCC CCTTCCAGAC CACCAGTTCC TCCTTGGAGG CTGTGCCCTT TGCCTCTGCG 
GCCAATGTAG CCTGTGGGGA AGGTGACAAG GACGAGACTC AGAGTCATTA TTTCCTGTGC 
AAGGAGAAGG CCCCCGATGT GTTCGACTGG GGCAGCTCGG GCCCCCTCTG TGTCAGCCCC 
AAGTATGGCT GCAACTTCAA CAATGGGGGC TGCCACCAGG ACTGCTTTGA AGGGGGGGAT 
GGCTCCTTCC TCTGCGGCTG CCGACCAGGA TTCCGGCTGC TGGATGACCT GGTGACCTGT 
GCCTCTCGAA ACCCTTGCAG CTCCAGCCCA TGTCGTGGGG GGGCCACGTG CGTCCTGGGA 
CCCCATGGGA AAAACTACAC GTGCCGCTGC CCCCAAGGGT ACCAGCTGGA CTCGAGTCAG 
CTGGACTGTG TGGACGTGGA TGAATGCCAG GACTCCCCCT GTGCCCAGGA GTGTGTCAAC 
ACCCCTGGGG GCTTCCGCTG CGAATGCTGG GTTGGCTATG AGCCGGGCGG TCCTGGAGAG 
GGGGCCTGTC AGGATGTGGA TGAGTGTGCT CTGGGTCGCT CGCCTTGCGC CCAGGGCTGC 
ACCAACACAG ATGGCTCATT TCACTGCTCC TGTGAGGAGG GCTACGTCCT GGCCGGGGAG 
GACGGGACTC AGTGCCAGGA CGTGGATGAG TGTGTGGGCC CGGGGGGCCC CCTCTGCGAC 
AGCTTGTGCT TCAACACACA AGGGTCCTTC CACTGTGGCT GCCTGCCAGG CTGGGTGCTG 
GCCCCAAATG GGGTCTCTTG CACCATGGGG CCTGTGTCTC TGGGACCACC ATCTGGGCCC 
CCCGATGAGG AGGACAAAGG AGAGAAAGAA GGGAGCACCG TGCCCCGTGC TGCAACAGCC 
AGTCCCACAA GGGGCCCCGA GGGCACCCCC AAGGCTACAC CCACCACAAG TAGACCTTCG 
CTGTCATCTG ACGCCCCCAT CACATCTGCC CCACTCAAGA TGCTGGCCCC CAGTGGGTCC 
CCAGGCGTCT GGAGGGAGCC CAGCATCCAT CACGCCACAG CTGCCTCTGG CCCCCAGGAG 
CCTGCAGGTG GGGACTCCTC CGTGGCCACA CAAAACAACG ATGGCACTGA CGGGCAAAAG 
CTGCTTTTAT TCTACATCCT AGGCACCGTG GTGGCCATCC TACTCCTGCT GGCCCTGGCT 
CTGGGGCTAC TGGTCTATCG CAAGCGGAGA GCGAAGAGGG AGGAGAAGAA GGAGAAGAAG 
CCCCAGAATG CGGCAGACAG TTACTCCTGG GTTCCAGAGC GAGCTGAGAG CAGGGCCATG 
GAGAACCAGT ACAGTCCGAC ACCTGGGACA GACTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium.
Matrix biology : journal of the International Society for Matrix Biology64112-127(2017 Dec)
Galvagni F,Nardi F,Spiga O,Trezza A,Tarticchio G,Pellicani R,Andreuzzi E,Caldi E,Toti P,Tosi GM,Santucci A,Iozzo RV,Mongiat M,Orlandini M

Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface.
Oncogene36(44)6097-6108(2017 Nov)
Khan KA,Naylor AJ,Khan A,Noy PJ,Mambretti M,Lodhia P,Athwal J,Korzystka A,Buckley CD,Willcox BE,Mohammed F,Bicknell R

Psoriasis and Pro-angiogenetic Factor CD93: Gene Expression and Association with Gene Polymorphism Suggests a Role in Disease Pathogenesis.
Acta dermato-venereologica97(8)916-921(2017 Aug)
Duvetorp A,Slind Olsen R,Skarstedt M,S?derman J,Seifert O

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CD93 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

ORF Insert Sequence:

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ORF Insert Sequence:

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