Gene Symbol | CNKSR2 |
Entrez Gene ID | 22866 |
Full Name | connector enhancer of kinase suppressor of Ras 2 |
Synonyms | CNK2,KSR2,MAGUIN,MRXSHG |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]. |
Disorder MIM: | |
Disorder Html: | Mental retardation, X-linked, syndromic, Houge type, 301008 (3) |