EYA2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EYA2
Entrez Gene ID	2139
Full Name	EYA transcriptional coactivator and phosphatase 2
Synonyms	EAB1
General protein information	Preferred Names EYA transcriptional coactivator and phosphatase 2 Names eyes absent homolog 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.12
Summary	This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may be post-translationally modified and may play a role in eye development. A similar protein in mice can act as a transcriptional activator. Alternative splicing results in multiple transcript variants, but the full-length natures of all of these variants have not yet been determined. [provided by RefSeq, Jul 2009].
Disorder MIM:	601654

mRNA and Protein(s)

mRNA	Protein	Name
XM_017027721.1	XP_016883210.1	eyes absent homolog 2 isoform X1
NM_005244.5	NP_005235.3	eyes absent homolog 2 isoform a
XM_017027721.2	XP_016883210.1	eyes absent homolog 2 isoform X1
NM_172110.3	NP_742108.2	eyes absent homolog 2 isoform c
NM_005244.4	NP_005235.3	eyes absent homolog 2 isoform a
XM_005260327.2	XP_005260384.1	eyes absent homolog 2 isoform X2

Pathways from BioSystems

Homologies

Homo sapiens (human)	EYA2	NP_005235.3
Xenopus tropicalis (tropical clawed frog)	eya2	NP_001090820.1
Pan troglodytes (chimpanzee)	EYA2	XP_003317029.1
	LOC716182	XP_002808001.1
Canis lupus familiaris (dog)	EYA2	XP_853061.3
Mus musculus (house mouse)	Eya2	NP_001258891.1
Gallus gallus (chicken)	EYA2	NP_990246.1
Danio rerio (zebrafish)	eya2	NP_001004558.1
Bos taurus (cattle)	EYA2	NP_001030541.1
Rattus norvegicus (Norway rat)	Eya2	NP_569111.1

Gene Ontology
Bibliography

Related articles in PubMed

Eya2 overexpression promotes the invasion of human astrocytoma through the regulation of ERK/MMP9 signaling.
Wen Z, Liang C, Pan Q, Wang Y
International journal of molecular medicine40(5)1315-1322(2017 Nov)

The EGFR/miR-338-3p/EYA2 axis controls breast tumor growth and lung metastasis.
Liang Y, Xu X, Wang T, Li Y, You W, Fu J, Liu Y, Jin S, Ji Q, Zhao W, Song Q, Li L, Hong T, Huang J, Lyu Z, Ye Q
Cell death & disease8(7)e2928(2017 Jul)

Eya2, a Target Activated by Plzf, Is Critical for
Ono R, Masuya M, Ishii S, Katayama N, Nosaka T
Molecular and cellular biology37(13)(2017 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

High EYA2 expression is associated with acute myeloid leukemia.
Title: Eya2, a Target Activated by Plzf, Is Critical for

results demonstrate that overexpression of miR-30a in lung adenocarcinoma A549 cells can inhibit cell migration and invasion, which is partially attributed to the decrease of EYA2 expression
Title: Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2.

EYA2 functions as a stimulant in lung adenocarcinoma pathogenesis.
Title: Aberrant hypomethylation and overexpression of the eyes absent homologue 2 suppresses tumor cell growth of human lung adenocarcinoma cells.

SIX1 and EYA are often co-overexpressed in tumors, and the SIX1-EYA2 interaction has been shown to be critical for metastasis in a breast cancer model.
Title: The SIX1-EYA transcriptional complex as a therapeutic target in cancer.

Decreased expression of EYA2 is associated with pancreatic adenocarcinomas.
Title: Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth.

The following EYA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EYA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28355	NM_172110.3 Latest version!	Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$194.50-$272.30 $389.00
OHu28396	NM_005244.5 Latest version!	Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$229.50-$321.30 $459.00
OHu52942	XM_005260327.2 Latest version!	Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu92953	XM_017027721.2 Latest version!	Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu92953	XM_017027721.1	Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu28396	NM_005244.4	Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$229.50-$321.30 $459.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EYA2 ( NM_172110.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_742108.2 Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu28355
Clone ID Related Accession (Same CDS sequence)	NM_172110.3
Accession Version	NM_172110.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	eyes absent homolog 2 isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC013882.2 and AL354766.17. On Jul 30, 2009 this sequence version replaced NM_172110.2. Transcript Variant: This variant (5) lacks an alternate in-frame segment in the 3' coding region, compared to variant 1, resulting in an isoform (c) that is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC013882.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTAGAAC TAGTGATCTC ACCCAGCCTC ACTGTAAACA GCGATTGTCT GGATAAACTG 
AAGTTTAACC GTGCTGACGC TGCTGTGTGG ACTCTGAGTG ACAGACAAGG CATCACCAAA 
TCGGCCCCCC TGAGAGTGTC CCAGCTCTTC TCCAGATCTT GCCCACGTGT CCTCCCCCGC 
CAGCCTTCCA CAGCCATGGC AGCCTACGGC CAGACGCAGT ACAGTGCGGG GATCCAGCAG 
GCTACCCCCT ATACAGCTTA CCCACCTCCA GCACAAGCCT ATGGAATCCC TTCCTACAGC 
ATCAAGACAG AAGACAGCTT GAACCATTCC CCTGGCCAGA GTGGATTCCT CAGCTATGGC 
TCCAGCTTCA GCACCTCACC CACTGGACAG AGCCCATACA CCTACCAGAT GCACGGCACA 
ACAGGGTTCT ATCAAGGAGG AAATGGACTG GGCAACGCAG CCGGTTTCGG GAGTGTGCAC 
CAGGACTATC CTTCCTACCC CGGCTTCCCC CAGAGCCAGT ACCCCCAGTA TTACGGCTCA 
TCCTACAACC CTCCCTACGT CCCGGCCAGC AGCATCTGCC CTTCGCCCCT CTCCACGTCC 
ACCTACGTCC TCCAGGAGGC ATCTCACAAC GTCCCCAACC AGAGTTCCGA GTCACTTGCT 
GGTGAATACA ACACACACAA TGGACCTTCC ACACCAGCGA AAGAGGGAGA CACAGACAGG 
CCGCACCGGG CCTCCGACGG GAAGCTCCGA GGCCGGTCTA AGAGGAGCAG TGACCCGTCC 
CCGGCAGGGG ACAATGAGAT TGAGCGTGTG TTCGTGTGGG ACTTGGATGA GACAATAATT 
ATTTTTCACT CCTTACTCAC GGGGACATTT GCATCCAGAT ACGGGAAGGA CACCACGACG 
TCCGTGCGCA TTGGCCTTAT GATGGAAGAG ATGATCTTCA ACCTTGCAGA TACACATCTG 
TTCTTCAATG ACCTGGAGGA TTGTGACCAG ATCCACGTTG ATGACGTCTC ATCAGATGAC 
AATGGCCAAG ATTTAAGCAC ATACAACTTC TCCGCTGACG GCTTCCACAG TTCGGCCCCA 
GGAGCCAACC TGTGCCTGGG CTCTGGCGTG CACGGCGGCG TGGACTGGAT GAGGAAGCTG 
GCCTTCCGCT ACCGGCGGGT GAAGGAGATG TACAATACCT ACAAGAACAA CGTTGGTGGG 
AAGGAGAGCT GCTTCGAGAG GATAATGCAG AGATTCGGCA GAAAAGCTGT CTACGTGGTG 
ATCGGTGATG GTGTGGAAGA GGAGCAAGGA GCGAAAAAGC ACAACATGCC TTTCTGGCGG 
ATATCCTGCC ACGCAGACCT GGAGGCACTG AGGCACGCCC TGGAGCTGGA GTATTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_742108.2
CDS	375..1754
Translation	MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL

Target ORF information:

RefSeq Version	NM_172110.3
Organism	Homo sapiens(human)
Definition	Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172110.3

ORF Insert Sequence:

ATGGTAGAAC TAGTGATCTC ACCCAGCCTC ACTGTAAACA GCGATTGTCT GGATAAACTG 
AAGTTTAACC GTGCTGACGC TGCTGTGTGG ACTCTGAGTG ACAGACAAGG CATCACCAAA 
TCGGCCCCCC TGAGAGTGTC CCAGCTCTTC TCCAGATCTT GCCCACGTGT CCTCCCCCGC 
CAGCCTTCCA CAGCCATGGC AGCCTACGGC CAGACGCAGT ACAGTGCGGG GATCCAGCAG 
GCTACCCCCT ATACAGCTTA CCCACCTCCA GCACAAGCCT ATGGAATCCC TTCCTACAGC 
ATCAAGACAG AAGACAGCTT GAACCATTCC CCTGGCCAGA GTGGATTCCT CAGCTATGGC 
TCCAGCTTCA GCACCTCACC CACTGGACAG AGCCCATACA CCTACCAGAT GCACGGCACA 
ACAGGGTTCT ATCAAGGAGG AAATGGACTG GGCAACGCAG CCGGTTTCGG GAGTGTGCAC 
CAGGACTATC CTTCCTACCC CGGCTTCCCC CAGAGCCAGT ACCCCCAGTA TTACGGCTCA 
TCCTACAACC CTCCCTACGT CCCGGCCAGC AGCATCTGCC CTTCGCCCCT CTCCACGTCC 
ACCTACGTCC TCCAGGAGGC ATCTCACAAC GTCCCCAACC AGAGTTCCGA GTCACTTGCT 
GGTGAATACA ACACACACAA TGGACCTTCC ACACCAGCGA AAGAGGGAGA CACAGACAGG 
CCGCACCGGG CCTCCGACGG GAAGCTCCGA GGCCGGTCTA AGAGGAGCAG TGACCCGTCC 
CCGGCAGGGG ACAATGAGAT TGAGCGTGTG TTCGTGTGGG ACTTGGATGA GACAATAATT 
ATTTTTCACT CCTTACTCAC GGGGACATTT GCATCCAGAT ACGGGAAGGA CACCACGACG 
TCCGTGCGCA TTGGCCTTAT GATGGAAGAG ATGATCTTCA ACCTTGCAGA TACACATCTG 
TTCTTCAATG ACCTGGAGGA TTGTGACCAG ATCCACGTTG ATGACGTCTC ATCAGATGAC 
AATGGCCAAG ATTTAAGCAC ATACAACTTC TCCGCTGACG GCTTCCACAG TTCGGCCCCA 
GGAGCCAACC TGTGCCTGGG CTCTGGCGTG CACGGCGGCG TGGACTGGAT GAGGAAGCTG 
GCCTTCCGCT ACCGGCGGGT GAAGGAGATG TACAATACCT ACAAGAACAA CGTTGGTGGG 
AAGGAGAGCT GCTTCGAGAG GATAATGCAG AGATTCGGCA GAAAAGCTGT CTACGTGGTG 
ATCGGTGATG GTGTGGAAGA GGAGCAAGGA GCGAAAAAGC ACAACATGCC TTTCTGGCGG 
ATATCCTGCC ACGCAGACCT GGAGGCACTG AGGCACGCCC TGGAGCTGGA GTATTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EYA2 ( NM_005244.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005235.3 Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28396
Clone ID Related Accession (Same CDS sequence)	NM_005244.5 , NM_005244.4
Accession Version	NM_005244.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1617bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	eyes absent homolog 2 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL354766.17, AL121776.19, AL359434.15 and AL022342.7. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_005244.4. Transcript Variant: This variant (1), also known as EYA2I, represents the longer transcript and encodes the longer isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK293032.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000327619.10/ ENSP00000333640.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTAGAAC TAGTGATCTC ACCCAGCCTC ACTGTAAACA GCGATTGTCT GGATAAACTG 
AAGTTTAACC GTGCTGACGC TGCTGTGTGG ACTCTGAGTG ACAGACAAGG CATCACCAAA 
TCGGCCCCCC TGAGAGTGTC CCAGCTCTTC TCCAGATCTT GCCCACGTGT CCTCCCCCGC 
CAGCCTTCCA CAGCCATGGC AGCCTACGGC CAGACGCAGT ACAGTGCGGG GATCCAGCAG 
GCTACCCCCT ATACAGCTTA CCCACCTCCA GCACAAGCCT ATGGAATCCC TTCCTACAGC 
ATCAAGACAG AAGACAGCTT GAACCATTCC CCTGGCCAGA GTGGATTCCT CAGCTATGGC 
TCCAGCTTCA GCACCTCACC CACTGGACAG AGCCCATACA CCTACCAGAT GCACGGCACA 
ACAGGGTTCT ATCAAGGAGG AAATGGACTG GGCAACGCAG CCGGTTTCGG GAGTGTGCAC 
CAGGACTATC CTTCCTACCC CGGCTTCCCC CAGAGCCAGT ACCCCCAGTA TTACGGCTCA 
TCCTACAACC CTCCCTACGT CCCGGCCAGC AGCATCTGCC CTTCGCCCCT CTCCACGTCC 
ACCTACGTCC TCCAGGAGGC ATCTCACAAC GTCCCCAACC AGAGTTCCGA GTCACTTGCT 
GGTGAATACA ACACACACAA TGGACCTTCC ACACCAGCGA AAGAGGGAGA CACAGACAGG 
CCGCACCGGG CCTCCGACGG GAAGCTCCGA GGCCGGTCTA AGAGGAGCAG TGACCCGTCC 
CCGGCAGGGG ACAATGAGAT TGAGCGTGTG TTCGTGTGGG ACTTGGATGA GACAATAATT 
ATTTTTCACT CCTTACTCAC GGGGACATTT GCATCCAGAT ACGGGAAGGA CACCACGACG 
TCCGTGCGCA TTGGCCTTAT GATGGAAGAG ATGATCTTCA ACCTTGCAGA TACACATCTG 
TTCTTCAATG ACCTGGAGGA TTGTGACCAG ATCCACGTTG ATGACGTCTC ATCAGATGAC 
AATGGCCAAG ATTTAAGCAC ATACAACTTC TCCGCTGACG GCTTCCACAG TTCGGCCCCA 
GGAGCCAACC TGTGCCTGGG CTCTGGCGTG CACGGCGGCG TGGACTGGAT GAGGAAGCTG 
GCCTTCCGCT ACCGGCGGGT GAAGGAGATG TACAATACCT ACAAGAACAA CGTTGGTGGG 
TTGATAGGCA CTCCCAAAAG GGAGACCTGG CTACAGCTCC GAGCTGAGCT GGAAGCTCTC 
ACAGACCTCT GGCTGACCCA CTCCCTGAAG GCACTAAACC TCATCAACTC CCGGCCCAAC 
TGTGTCAATG TGCTGGTCAC CACCACTCAA CTAATTCCTG CCCTGGCCAA AGTCCTGCTA 
TATGGCCTGG GGTCTGTGTT TCCTATTGAG AACATCTACA GTGCAACCAA GACAGGGAAG 
GAGAGCTGCT TCGAGAGGAT AATGCAGAGA TTCGGCAGAA AAGCTGTCTA CGTGGTGATC 
GGTGATGGTG TGGAAGAGGA GCAAGGAGCG AAAAAGCACA ACATGCCTTT CTGGCGGATA 
TCCTGCCACG CAGACCTGGA GGCACTGAGG CACGCCCTGG AGCTGGAGTA TTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005235.3
CDS	156..1772
Translation	MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL

Target ORF information:

RefSeq Version	NM_005244.5
Organism	Homo sapiens(human)
Definition	Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005244.5

ORF Insert Sequence:

ATGGTAGAAC TAGTGATCTC ACCCAGCCTC ACTGTAAACA GCGATTGTCT GGATAAACTG 
AAGTTTAACC GTGCTGACGC TGCTGTGTGG ACTCTGAGTG ACAGACAAGG CATCACCAAA 
TCGGCCCCCC TGAGAGTGTC CCAGCTCTTC TCCAGATCTT GCCCACGTGT CCTCCCCCGC 
CAGCCTTCCA CAGCCATGGC AGCCTACGGC CAGACGCAGT ACAGTGCGGG GATCCAGCAG 
GCTACCCCCT ATACAGCTTA CCCACCTCCA GCACAAGCCT ATGGAATCCC TTCCTACAGC 
ATCAAGACAG AAGACAGCTT GAACCATTCC CCTGGCCAGA GTGGATTCCT CAGCTATGGC 
TCCAGCTTCA GCACCTCACC CACTGGACAG AGCCCATACA CCTACCAGAT GCACGGCACA 
ACAGGGTTCT ATCAAGGAGG AAATGGACTG GGCAACGCAG CCGGTTTCGG GAGTGTGCAC 
CAGGACTATC CTTCCTACCC CGGCTTCCCC CAGAGCCAGT ACCCCCAGTA TTACGGCTCA 
TCCTACAACC CTCCCTACGT CCCGGCCAGC AGCATCTGCC CTTCGCCCCT CTCCACGTCC 
ACCTACGTCC TCCAGGAGGC ATCTCACAAC GTCCCCAACC AGAGTTCCGA GTCACTTGCT 
GGTGAATACA ACACACACAA TGGACCTTCC ACACCAGCGA AAGAGGGAGA CACAGACAGG 
CCGCACCGGG CCTCCGACGG GAAGCTCCGA GGCCGGTCTA AGAGGAGCAG TGACCCGTCC 
CCGGCAGGGG ACAATGAGAT TGAGCGTGTG TTCGTGTGGG ACTTGGATGA GACAATAATT 
ATTTTTCACT CCTTACTCAC GGGGACATTT GCATCCAGAT ACGGGAAGGA CACCACGACG 
TCCGTGCGCA TTGGCCTTAT GATGGAAGAG ATGATCTTCA ACCTTGCAGA TACACATCTG 
TTCTTCAATG ACCTGGAGGA TTGTGACCAG ATCCACGTTG ATGACGTCTC ATCAGATGAC 
AATGGCCAAG ATTTAAGCAC ATACAACTTC TCCGCTGACG GCTTCCACAG TTCGGCCCCA 
GGAGCCAACC TGTGCCTGGG CTCTGGCGTG CACGGCGGCG TGGACTGGAT GAGGAAGCTG 
GCCTTCCGCT ACCGGCGGGT GAAGGAGATG TACAATACCT ACAAGAACAA CGTTGGTGGG 
TTGATAGGCA CTCCCAAAAG GGAGACCTGG CTACAGCTCC GAGCTGAGCT GGAAGCTCTC 
ACAGACCTCT GGCTGACCCA CTCCCTGAAG GCACTAAACC TCATCAACTC CCGGCCCAAC 
TGTGTCAATG TGCTGGTCAC CACCACTCAA CTAATTCCTG CCCTGGCCAA AGTCCTGCTA 
TATGGCCTGG GGTCTGTGTT TCCTATTGAG AACATCTACA GTGCAACCAA GACAGGGAAG 
GAGAGCTGCT TCGAGAGGAT AATGCAGAGA TTCGGCAGAA AAGCTGTCTA CGTGGTGATC 
GGTGATGGTG TGGAAGAGGA GCAAGGAGCG AAAAAGCACA ACATGCCTTT CTGGCGGATA 
TCCTGCCACG CAGACCTGGA GGCACTGAGG CACGCCCTGG AGCTGGAGTA TTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EYA2 ( NM_005244.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005235.3 Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28396
Clone ID Related Accession (Same CDS sequence)	NM_005244.5 , NM_005244.4
Accession Version	NM_005244.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1617bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-17
Organism	Homo sapiens(human)
Product	eyes absent homolog 2 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL354766.17, AL121776.19, AL359434.15 and AL022342.7. This sequence is a reference standard in the RefSeqGene project. On Apr 25, 2009 this sequence version replaced NM_005244.3. Transcript Variant: This variant (1), also known as EYA2I, represents the longer transcript and encodes the longer isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: SRR1660803.69645.1, U71207.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTAGAAC TAGTGATCTC ACCCAGCCTC ACTGTAAACA GCGATTGTCT GGATAAACTG 
AAGTTTAACC GTGCTGACGC TGCTGTGTGG ACTCTGAGTG ACAGACAAGG CATCACCAAA 
TCGGCCCCCC TGAGAGTGTC CCAGCTCTTC TCCAGATCTT GCCCACGTGT CCTCCCCCGC 
CAGCCTTCCA CAGCCATGGC AGCCTACGGC CAGACGCAGT ACAGTGCGGG GATCCAGCAG 
GCTACCCCCT ATACAGCTTA CCCACCTCCA GCACAAGCCT ATGGAATCCC TTCCTACAGC 
ATCAAGACAG AAGACAGCTT GAACCATTCC CCTGGCCAGA GTGGATTCCT CAGCTATGGC 
TCCAGCTTCA GCACCTCACC CACTGGACAG AGCCCATACA CCTACCAGAT GCACGGCACA 
ACAGGGTTCT ATCAAGGAGG AAATGGACTG GGCAACGCAG CCGGTTTCGG GAGTGTGCAC 
CAGGACTATC CTTCCTACCC CGGCTTCCCC CAGAGCCAGT ACCCCCAGTA TTACGGCTCA 
TCCTACAACC CTCCCTACGT CCCGGCCAGC AGCATCTGCC CTTCGCCCCT CTCCACGTCC 
ACCTACGTCC TCCAGGAGGC ATCTCACAAC GTCCCCAACC AGAGTTCCGA GTCACTTGCT 
GGTGAATACA ACACACACAA TGGACCTTCC ACACCAGCGA AAGAGGGAGA CACAGACAGG 
CCGCACCGGG CCTCCGACGG GAAGCTCCGA GGCCGGTCTA AGAGGAGCAG TGACCCGTCC 
CCGGCAGGGG ACAATGAGAT TGAGCGTGTG TTCGTGTGGG ACTTGGATGA GACAATAATT 
ATTTTTCACT CCTTACTCAC GGGGACATTT GCATCCAGAT ACGGGAAGGA CACCACGACG 
TCCGTGCGCA TTGGCCTTAT GATGGAAGAG ATGATCTTCA ACCTTGCAGA TACACATCTG 
TTCTTCAATG ACCTGGAGGA TTGTGACCAG ATCCACGTTG ATGACGTCTC ATCAGATGAC 
AATGGCCAAG ATTTAAGCAC ATACAACTTC TCCGCTGACG GCTTCCACAG TTCGGCCCCA 
GGAGCCAACC TGTGCCTGGG CTCTGGCGTG CACGGCGGCG TGGACTGGAT GAGGAAGCTG 
GCCTTCCGCT ACCGGCGGGT GAAGGAGATG TACAATACCT ACAAGAACAA CGTTGGTGGG 
TTGATAGGCA CTCCCAAAAG GGAGACCTGG CTACAGCTCC GAGCTGAGCT GGAAGCTCTC 
ACAGACCTCT GGCTGACCCA CTCCCTGAAG GCACTAAACC TCATCAACTC CCGGCCCAAC 
TGTGTCAATG TGCTGGTCAC CACCACTCAA CTAATTCCTG CCCTGGCCAA AGTCCTGCTA 
TATGGCCTGG GGTCTGTGTT TCCTATTGAG AACATCTACA GTGCAACCAA GACAGGGAAG 
GAGAGCTGCT TCGAGAGGAT AATGCAGAGA TTCGGCAGAA AAGCTGTCTA CGTGGTGATC 
GGTGATGGTG TGGAAGAGGA GCAAGGAGCG AAAAAGCACA ACATGCCTTT CTGGCGGATA 
TCCTGCCACG CAGACCTGGA GGCACTGAGG CACGCCCTGG AGCTGGAGTA TTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005235.3
CDS	375..1991
Translation	MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL

Target ORF information:

RefSeq Version	NM_005244.4
Organism	Homo sapiens(human)
Definition	Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005244.4

ORF Insert Sequence:

ATGGTAGAAC TAGTGATCTC ACCCAGCCTC ACTGTAAACA GCGATTGTCT GGATAAACTG 
AAGTTTAACC GTGCTGACGC TGCTGTGTGG ACTCTGAGTG ACAGACAAGG CATCACCAAA 
TCGGCCCCCC TGAGAGTGTC CCAGCTCTTC TCCAGATCTT GCCCACGTGT CCTCCCCCGC 
CAGCCTTCCA CAGCCATGGC AGCCTACGGC CAGACGCAGT ACAGTGCGGG GATCCAGCAG 
GCTACCCCCT ATACAGCTTA CCCACCTCCA GCACAAGCCT ATGGAATCCC TTCCTACAGC 
ATCAAGACAG AAGACAGCTT GAACCATTCC CCTGGCCAGA GTGGATTCCT CAGCTATGGC 
TCCAGCTTCA GCACCTCACC CACTGGACAG AGCCCATACA CCTACCAGAT GCACGGCACA 
ACAGGGTTCT ATCAAGGAGG AAATGGACTG GGCAACGCAG CCGGTTTCGG GAGTGTGCAC 
CAGGACTATC CTTCCTACCC CGGCTTCCCC CAGAGCCAGT ACCCCCAGTA TTACGGCTCA 
TCCTACAACC CTCCCTACGT CCCGGCCAGC AGCATCTGCC CTTCGCCCCT CTCCACGTCC 
ACCTACGTCC TCCAGGAGGC ATCTCACAAC GTCCCCAACC AGAGTTCCGA GTCACTTGCT 
GGTGAATACA ACACACACAA TGGACCTTCC ACACCAGCGA AAGAGGGAGA CACAGACAGG 
CCGCACCGGG CCTCCGACGG GAAGCTCCGA GGCCGGTCTA AGAGGAGCAG TGACCCGTCC 
CCGGCAGGGG ACAATGAGAT TGAGCGTGTG TTCGTGTGGG ACTTGGATGA GACAATAATT 
ATTTTTCACT CCTTACTCAC GGGGACATTT GCATCCAGAT ACGGGAAGGA CACCACGACG 
TCCGTGCGCA TTGGCCTTAT GATGGAAGAG ATGATCTTCA ACCTTGCAGA TACACATCTG 
TTCTTCAATG ACCTGGAGGA TTGTGACCAG ATCCACGTTG ATGACGTCTC ATCAGATGAC 
AATGGCCAAG ATTTAAGCAC ATACAACTTC TCCGCTGACG GCTTCCACAG TTCGGCCCCA 
GGAGCCAACC TGTGCCTGGG CTCTGGCGTG CACGGCGGCG TGGACTGGAT GAGGAAGCTG 
GCCTTCCGCT ACCGGCGGGT GAAGGAGATG TACAATACCT ACAAGAACAA CGTTGGTGGG 
TTGATAGGCA CTCCCAAAAG GGAGACCTGG CTACAGCTCC GAGCTGAGCT GGAAGCTCTC 
ACAGACCTCT GGCTGACCCA CTCCCTGAAG GCACTAAACC TCATCAACTC CCGGCCCAAC 
TGTGTCAATG TGCTGGTCAC CACCACTCAA CTAATTCCTG CCCTGGCCAA AGTCCTGCTA 
TATGGCCTGG GGTCTGTGTT TCCTATTGAG AACATCTACA GTGCAACCAA GACAGGGAAG 
GAGAGCTGCT TCGAGAGGAT AATGCAGAGA TTCGGCAGAA AAGCTGTCTA CGTGGTGATC 
GGTGATGGTG TGGAAGAGGA GCAAGGAGCG AAAAAGCACA ACATGCCTTT CTGGCGGATA 
TCCTGCCACG CAGACCTGGA GGCACTGAGG CACGCCCTGG AGCTGGAGTA TTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EYA2 ( XM_005260327.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005260384.1 Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant X2, mRNA.

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CloneID	OHu52942
Clone ID Related Accession (Same CDS sequence)	XM_005260327.2
Accession Version	XM_005260327.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	eyes absent homolog 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005260327.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTAGAAC TAGTGATCTC ACCCAGCCTC ACTGTAAACA GCGATTGTCT GGATAAACTG 
AAGTTTAACC GTGCTGACGC TGCTGTGTGG ACTCTGAGTG ACAGACAAGG CATCACCAAA 
TCGGCCCCCC TGAGAGTGTC CCAGCTCTTC TCCAGATCTT GCCCACGTGT CCTCCCCCGC 
CAGCCTTCCA CAGCCATGGC AGCCTACGGC CAGACGCAGT ACAGTGCGGG GATCCAGCAG 
GCTACCCCCT ATACAGCTTA CCCACCTCCA GCACAAGCCT ATGGAATCCC TTCCTACAGC 
ATCAAGACAG AAGACAGCTT GAACCATTCC CCTGGCCAGA GTGGATTCCT CAGCTATGGC 
TCCAGCTTCA GCACCTCACC CACTGGACAG AGCCCATACA CCTACCAGAT GCACGGTGAA 
TACAACACAC ACAATGGACC TTCCACACCA GCGAAAGAGG GAGACACAGA CAGGCCGCAC 
CGGGCCTCCG ACGGGAAGCT CCGAGGCCGG TCTAAGAGGA GCAGTGACCC GTCCCCGGCA 
GGGGACAATG AGATTGAGCG TGTGTTCGTG TGGGACTTGG ATGAGACAAT AATTATTTTT 
CACTCCTTAC TCACGGGGAC ATTTGCATCC AGATACGGGA AGGACACCAC GACGTCCGTG 
CGCATTGGCC TTATGATGGA AGAGATGATC TTCAACCTTG CAGATACACA TCTGTTCTTC 
AATGACCTGG AGGATTGTGA CCAGATCCAC GTTGATGACG TCTCATCAGA TGACAATGGC 
CAAGATTTAA GCACATACAA CTTCTCCGCT GACGGCTTCC ACAGTTCGGC CCCAGGAGCC 
AACCTGTGCC TGGGCTCTGG CGTGCACGGC GGCGTGGACT GGATGAGGAA GCTGGCCTTC 
CGCTACCGGC GGGTGAAGGA GATGTACAAT ACCTACAAGA ACAACGTTGG TGGGTTGATA 
GGCACTCCCA AAAGGGAGAC CTGGCTACAG CTCCGAGCTG AGCTGGAAGC TCTCACAGAC 
CTCTGGCTGA CCCACTCCCT GAAGGCACTA AACCTCATCA ACTCCCGGCC CAACTGTGTC 
AATGTGCTGG TCACCACCAC TCAACTAATT CCTGCCCTGG CCAAAGTCCT GCTATATGGC 
CTGGGGTCTG TGTTTCCTAT TGAGAACATC TACAGTGCAA CCAAGACAGG GAAGGAGAGC 
TGCTTCGAGA GGATAATGCA GAGATTCGGC AGAAAAGCTG TCTACGTGGT GATCGGTGAT 
GGTGTGGAAG AGGAGCAAGG AGCGAAAAAG CACAACATGC CTTTCTGGCG GATATCCTGC 
CACGCAGACC TGGAGGCACT GAGGCACGCC CTGGAGCTGG AGTATTTATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005260384.1
CDS	68..1438
Translation	MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL

Target ORF information:

RefSeq Version	XM_005260327.2
Organism	Homo sapiens(human)
Definition	Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005260327.2

ORF Insert Sequence:

ATGGTAGAAC TAGTGATCTC ACCCAGCCTC ACTGTAAACA GCGATTGTCT GGATAAACTG 
AAGTTTAACC GTGCTGACGC TGCTGTGTGG ACTCTGAGTG ACAGACAAGG CATCACCAAA 
TCGGCCCCCC TGAGAGTGTC CCAGCTCTTC TCCAGATCTT GCCCACGTGT CCTCCCCCGC 
CAGCCTTCCA CAGCCATGGC AGCCTACGGC CAGACGCAGT ACAGTGCGGG GATCCAGCAG 
GCTACCCCCT ATACAGCTTA CCCACCTCCA GCACAAGCCT ATGGAATCCC TTCCTACAGC 
ATCAAGACAG AAGACAGCTT GAACCATTCC CCTGGCCAGA GTGGATTCCT CAGCTATGGC 
TCCAGCTTCA GCACCTCACC CACTGGACAG AGCCCATACA CCTACCAGAT GCACGGTGAA 
TACAACACAC ACAATGGACC TTCCACACCA GCGAAAGAGG GAGACACAGA CAGGCCGCAC 
CGGGCCTCCG ACGGGAAGCT CCGAGGCCGG TCTAAGAGGA GCAGTGACCC GTCCCCGGCA 
GGGGACAATG AGATTGAGCG TGTGTTCGTG TGGGACTTGG ATGAGACAAT AATTATTTTT 
CACTCCTTAC TCACGGGGAC ATTTGCATCC AGATACGGGA AGGACACCAC GACGTCCGTG 
CGCATTGGCC TTATGATGGA AGAGATGATC TTCAACCTTG CAGATACACA TCTGTTCTTC 
AATGACCTGG AGGATTGTGA CCAGATCCAC GTTGATGACG TCTCATCAGA TGACAATGGC 
CAAGATTTAA GCACATACAA CTTCTCCGCT GACGGCTTCC ACAGTTCGGC CCCAGGAGCC 
AACCTGTGCC TGGGCTCTGG CGTGCACGGC GGCGTGGACT GGATGAGGAA GCTGGCCTTC 
CGCTACCGGC GGGTGAAGGA GATGTACAAT ACCTACAAGA ACAACGTTGG TGGGTTGATA 
GGCACTCCCA AAAGGGAGAC CTGGCTACAG CTCCGAGCTG AGCTGGAAGC TCTCACAGAC 
CTCTGGCTGA CCCACTCCCT GAAGGCACTA AACCTCATCA ACTCCCGGCC CAACTGTGTC 
AATGTGCTGG TCACCACCAC TCAACTAATT CCTGCCCTGG CCAAAGTCCT GCTATATGGC 
CTGGGGTCTG TGTTTCCTAT TGAGAACATC TACAGTGCAA CCAAGACAGG GAAGGAGAGC 
TGCTTCGAGA GGATAATGCA GAGATTCGGC AGAAAAGCTG TCTACGTGGT GATCGGTGAT 
GGTGTGGAAG AGGAGCAAGG AGCGAAAAAG CACAACATGC CTTTCTGGCG GATATCCTGC 
CACGCAGACC TGGAGGCACT GAGGCACGCC CTGGAGCTGG AGTATTTATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EYA2 ( XM_017027721.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016883210.1 Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu92953
Clone ID Related Accession (Same CDS sequence)	XM_017027721.1 , XM_017027721.2
Accession Version	XM_017027721.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	eyes absent homolog 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTAGAAC TAGTGATCTC ACCCAGCCTC ACTGTAAACA GCGATTGTCT GGATAAACTG 
AAGTTTAACC GTGCTGACGC TGCTGTGTGG ACTCTGAGTG ACAGACAAGG CATCACCAAA 
TCGGCCCCCC TGAGAGTGTC CCAGCTCTTC TCCAGATCTT GCCCACGTGT CCTCCCCCGC 
CAGCCTTCCA CAGCCATGGC AGCCTACGGC CAGACGCAGT ACAGTGCGGG GATCCAGCAG 
GCTACCCCCT ATACAGCTTA CCCACCTCCA GCACAAGCCT ATGGAATCCC TTCCTACAGC 
ATCAAGACAG AAGACAGCTT GAACCATTCC CCTGGCCAGA GTGGATTCCT CAGCTATGGC 
TCCAGCTTCA GCACCTCACC CACTGGACAG AGCCCATACA CCTACCAGAT GCACGGCACA 
ACAGGGTTCT ATCAAGGAGG AAATGGACTG GGCAACGCAG CCGGTTTCGG GAGTGTGCAC 
CAGGACTATC CTTCCTACCC CGGCTTCCCC CAGAGCCAGT ACCCCCAGTA TTACGGCTCA 
TCCTACAACC CTCCCTACGT CCCGGCCAGC AGCATCTGCC CTTCGCCCCT CTCCACGTCC 
ACCTACGTCC TCCAGGAGGC ATCTCACAAC GTCCCCAACC AGAGTTCCGA GTCACTTGCT 
GGTGAATACA ACACACACAA TGGACCTTCC ACACCAGCGA AAGAGGGAGA CACAGACAGG 
CCGCACCGGG CCTCCGACGG GAAGCTCCGA GGCCGGTCTA AGAGGAGCAG TGACCCGTCC 
CCGGCAGGGG ACAATGAGAT TGAGCGTGTG TTCGTGTGGG ACTTGGATGA GACAATAATT 
ATTTTTCACT CCTTACTCAC GGGGACATTT GCATCCAGAT ACGGGAAGGA TTGTGACCAG 
ATCCACGTTG ATGACGTCTC ATCAGATGAC AATGGCCAAG ATTTAAGCAC ATACAACTTC 
TCCGCTGACG GCTTCCACAG TTCGGCCCCA GGAGCCAACC TGTGCCTGGG CTCTGGCGTG 
CACGGCGGCG TGGACTGGAT GAGGAAGCTG GCCTTCCGCT ACCGGCGGGT GAAGGAGATG 
TACAATACCT ACAAGAACAA CGTTGGTGGG TTGATAGGCA CTCCCAAAAG GGAGACCTGG 
CTACAGCTCC GAGCTGAGCT GGAAGCTCTC ACAGACCTCT GGCTGACCCA CTCCCTGAAG 
GCACTAAACC TCATCAACTC CCGGCCCAAC TGTGTCAATG TGCTGGTCAC CACCACTCAA 
CTAATTCCTG CCCTGGCCAA AGTCCTGCTA TATGGCCTGG GGTCTGTGTT TCCTATTGAG 
AACATCTACA GTGCAACCAA GACAGGGAAG GAGAGCTGCT TCGAGAGGAT AATGCAGAGA 
TTCGGCAGAA AAGCTGTCTA CGTGGTGATC GGTGATGGTG TGGAAGAGGA GCAAGGAGCG 
AAAAAGCACA ACATGCCTTT CTGGCGGATA TCCTGCCACG CAGACCTGGA GGCACTGAGG 
CACGCCCTGG AGCTGGAGTA TTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016883210.1
CDS	93..1619
Translation	MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL

Target ORF information:

RefSeq Version	XM_017027721.1
Organism	Homo sapiens(human)
Definition	Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027721.1

ORF Insert Sequence:

ATGGTAGAAC TAGTGATCTC ACCCAGCCTC ACTGTAAACA GCGATTGTCT GGATAAACTG 
AAGTTTAACC GTGCTGACGC TGCTGTGTGG ACTCTGAGTG ACAGACAAGG CATCACCAAA 
TCGGCCCCCC TGAGAGTGTC CCAGCTCTTC TCCAGATCTT GCCCACGTGT CCTCCCCCGC 
CAGCCTTCCA CAGCCATGGC AGCCTACGGC CAGACGCAGT ACAGTGCGGG GATCCAGCAG 
GCTACCCCCT ATACAGCTTA CCCACCTCCA GCACAAGCCT ATGGAATCCC TTCCTACAGC 
ATCAAGACAG AAGACAGCTT GAACCATTCC CCTGGCCAGA GTGGATTCCT CAGCTATGGC 
TCCAGCTTCA GCACCTCACC CACTGGACAG AGCCCATACA CCTACCAGAT GCACGGCACA 
ACAGGGTTCT ATCAAGGAGG AAATGGACTG GGCAACGCAG CCGGTTTCGG GAGTGTGCAC 
CAGGACTATC CTTCCTACCC CGGCTTCCCC CAGAGCCAGT ACCCCCAGTA TTACGGCTCA 
TCCTACAACC CTCCCTACGT CCCGGCCAGC AGCATCTGCC CTTCGCCCCT CTCCACGTCC 
ACCTACGTCC TCCAGGAGGC ATCTCACAAC GTCCCCAACC AGAGTTCCGA GTCACTTGCT 
GGTGAATACA ACACACACAA TGGACCTTCC ACACCAGCGA AAGAGGGAGA CACAGACAGG 
CCGCACCGGG CCTCCGACGG GAAGCTCCGA GGCCGGTCTA AGAGGAGCAG TGACCCGTCC 
CCGGCAGGGG ACAATGAGAT TGAGCGTGTG TTCGTGTGGG ACTTGGATGA GACAATAATT 
ATTTTTCACT CCTTACTCAC GGGGACATTT GCATCCAGAT ACGGGAAGGA TTGTGACCAG 
ATCCACGTTG ATGACGTCTC ATCAGATGAC AATGGCCAAG ATTTAAGCAC ATACAACTTC 
TCCGCTGACG GCTTCCACAG TTCGGCCCCA GGAGCCAACC TGTGCCTGGG CTCTGGCGTG 
CACGGCGGCG TGGACTGGAT GAGGAAGCTG GCCTTCCGCT ACCGGCGGGT GAAGGAGATG 
TACAATACCT ACAAGAACAA CGTTGGTGGG TTGATAGGCA CTCCCAAAAG GGAGACCTGG 
CTACAGCTCC GAGCTGAGCT GGAAGCTCTC ACAGACCTCT GGCTGACCCA CTCCCTGAAG 
GCACTAAACC TCATCAACTC CCGGCCCAAC TGTGTCAATG TGCTGGTCAC CACCACTCAA 
CTAATTCCTG CCCTGGCCAA AGTCCTGCTA TATGGCCTGG GGTCTGTGTT TCCTATTGAG 
AACATCTACA GTGCAACCAA GACAGGGAAG GAGAGCTGCT TCGAGAGGAT AATGCAGAGA 
TTCGGCAGAA AAGCTGTCTA CGTGGTGATC GGTGATGGTG TGGAAGAGGA GCAAGGAGCG 
AAAAAGCACA ACATGCCTTT CTGGCGGATA TCCTGCCACG CAGACCTGGA GGCACTGAGG 
CACGCCCTGG AGCTGGAGTA TTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EYA2 ( XM_017027721.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016883210.1 Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu92953
Clone ID Related Accession (Same CDS sequence)	XM_017027721.1 , XM_017027721.2
Accession Version	XM_017027721.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	eyes absent homolog 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017027721.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTAGAAC TAGTGATCTC ACCCAGCCTC ACTGTAAACA GCGATTGTCT GGATAAACTG 
AAGTTTAACC GTGCTGACGC TGCTGTGTGG ACTCTGAGTG ACAGACAAGG CATCACCAAA 
TCGGCCCCCC TGAGAGTGTC CCAGCTCTTC TCCAGATCTT GCCCACGTGT CCTCCCCCGC 
CAGCCTTCCA CAGCCATGGC AGCCTACGGC CAGACGCAGT ACAGTGCGGG GATCCAGCAG 
GCTACCCCCT ATACAGCTTA CCCACCTCCA GCACAAGCCT ATGGAATCCC TTCCTACAGC 
ATCAAGACAG AAGACAGCTT GAACCATTCC CCTGGCCAGA GTGGATTCCT CAGCTATGGC 
TCCAGCTTCA GCACCTCACC CACTGGACAG AGCCCATACA CCTACCAGAT GCACGGCACA 
ACAGGGTTCT ATCAAGGAGG AAATGGACTG GGCAACGCAG CCGGTTTCGG GAGTGTGCAC 
CAGGACTATC CTTCCTACCC CGGCTTCCCC CAGAGCCAGT ACCCCCAGTA TTACGGCTCA 
TCCTACAACC CTCCCTACGT CCCGGCCAGC AGCATCTGCC CTTCGCCCCT CTCCACGTCC 
ACCTACGTCC TCCAGGAGGC ATCTCACAAC GTCCCCAACC AGAGTTCCGA GTCACTTGCT 
GGTGAATACA ACACACACAA TGGACCTTCC ACACCAGCGA AAGAGGGAGA CACAGACAGG 
CCGCACCGGG CCTCCGACGG GAAGCTCCGA GGCCGGTCTA AGAGGAGCAG TGACCCGTCC 
CCGGCAGGGG ACAATGAGAT TGAGCGTGTG TTCGTGTGGG ACTTGGATGA GACAATAATT 
ATTTTTCACT CCTTACTCAC GGGGACATTT GCATCCAGAT ACGGGAAGGA TTGTGACCAG 
ATCCACGTTG ATGACGTCTC ATCAGATGAC AATGGCCAAG ATTTAAGCAC ATACAACTTC 
TCCGCTGACG GCTTCCACAG TTCGGCCCCA GGAGCCAACC TGTGCCTGGG CTCTGGCGTG 
CACGGCGGCG TGGACTGGAT GAGGAAGCTG GCCTTCCGCT ACCGGCGGGT GAAGGAGATG 
TACAATACCT ACAAGAACAA CGTTGGTGGG TTGATAGGCA CTCCCAAAAG GGAGACCTGG 
CTACAGCTCC GAGCTGAGCT GGAAGCTCTC ACAGACCTCT GGCTGACCCA CTCCCTGAAG 
GCACTAAACC TCATCAACTC CCGGCCCAAC TGTGTCAATG TGCTGGTCAC CACCACTCAA 
CTAATTCCTG CCCTGGCCAA AGTCCTGCTA TATGGCCTGG GGTCTGTGTT TCCTATTGAG 
AACATCTACA GTGCAACCAA GACAGGGAAG GAGAGCTGCT TCGAGAGGAT AATGCAGAGA 
TTCGGCAGAA AAGCTGTCTA CGTGGTGATC GGTGATGGTG TGGAAGAGGA GCAAGGAGCG 
AAAAAGCACA ACATGCCTTT CTGGCGGATA TCCTGCCACG CAGACCTGGA GGCACTGAGG 
CACGCCCTGG AGCTGGAGTA TTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016883210.1
CDS	112..1638
Translation	MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL

Target ORF information:

RefSeq Version	XM_017027721.2
Organism	Homo sapiens(human)
Definition	Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027721.2

ORF Insert Sequence:

ATGGTAGAAC TAGTGATCTC ACCCAGCCTC ACTGTAAACA GCGATTGTCT GGATAAACTG 
AAGTTTAACC GTGCTGACGC TGCTGTGTGG ACTCTGAGTG ACAGACAAGG CATCACCAAA 
TCGGCCCCCC TGAGAGTGTC CCAGCTCTTC TCCAGATCTT GCCCACGTGT CCTCCCCCGC 
CAGCCTTCCA CAGCCATGGC AGCCTACGGC CAGACGCAGT ACAGTGCGGG GATCCAGCAG 
GCTACCCCCT ATACAGCTTA CCCACCTCCA GCACAAGCCT ATGGAATCCC TTCCTACAGC 
ATCAAGACAG AAGACAGCTT GAACCATTCC CCTGGCCAGA GTGGATTCCT CAGCTATGGC 
TCCAGCTTCA GCACCTCACC CACTGGACAG AGCCCATACA CCTACCAGAT GCACGGCACA 
ACAGGGTTCT ATCAAGGAGG AAATGGACTG GGCAACGCAG CCGGTTTCGG GAGTGTGCAC 
CAGGACTATC CTTCCTACCC CGGCTTCCCC CAGAGCCAGT ACCCCCAGTA TTACGGCTCA 
TCCTACAACC CTCCCTACGT CCCGGCCAGC AGCATCTGCC CTTCGCCCCT CTCCACGTCC 
ACCTACGTCC TCCAGGAGGC ATCTCACAAC GTCCCCAACC AGAGTTCCGA GTCACTTGCT 
GGTGAATACA ACACACACAA TGGACCTTCC ACACCAGCGA AAGAGGGAGA CACAGACAGG 
CCGCACCGGG CCTCCGACGG GAAGCTCCGA GGCCGGTCTA AGAGGAGCAG TGACCCGTCC 
CCGGCAGGGG ACAATGAGAT TGAGCGTGTG TTCGTGTGGG ACTTGGATGA GACAATAATT 
ATTTTTCACT CCTTACTCAC GGGGACATTT GCATCCAGAT ACGGGAAGGA TTGTGACCAG 
ATCCACGTTG ATGACGTCTC ATCAGATGAC AATGGCCAAG ATTTAAGCAC ATACAACTTC 
TCCGCTGACG GCTTCCACAG TTCGGCCCCA GGAGCCAACC TGTGCCTGGG CTCTGGCGTG 
CACGGCGGCG TGGACTGGAT GAGGAAGCTG GCCTTCCGCT ACCGGCGGGT GAAGGAGATG 
TACAATACCT ACAAGAACAA CGTTGGTGGG TTGATAGGCA CTCCCAAAAG GGAGACCTGG 
CTACAGCTCC GAGCTGAGCT GGAAGCTCTC ACAGACCTCT GGCTGACCCA CTCCCTGAAG 
GCACTAAACC TCATCAACTC CCGGCCCAAC TGTGTCAATG TGCTGGTCAC CACCACTCAA 
CTAATTCCTG CCCTGGCCAA AGTCCTGCTA TATGGCCTGG GGTCTGTGTT TCCTATTGAG 
AACATCTACA GTGCAACCAA GACAGGGAAG GAGAGCTGCT TCGAGAGGAT AATGCAGAGA 
TTCGGCAGAA AAGCTGTCTA CGTGGTGATC GGTGATGGTG TGGAAGAGGA GCAAGGAGCG 
AAAAAGCACA ACATGCCTTT CTGGCGGATA TCCTGCCACG CAGACCTGGA GGCACTGAGG 
CACGCCCTGG AGCTGGAGTA TTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Eya2 overexpression promotes the invasion of human astrocytoma through the regulation of ERK/MMP9 signaling.
International journal of molecular medicine40(5)1315-1322(2017 Nov)
Wen Z,Liang C,Pan Q,Wang Y

The EGFR/miR-338-3p/EYA2 axis controls breast tumor growth and lung metastasis.
Cell death & disease8(7)e2928(2017 Jul)
Liang Y,Xu X,Wang T,Li Y,You W,Fu J,Liu Y,Jin S,Ji Q,Zhao W,Song Q,Li L,Hong T,Huang J,Lyu Z,Ye Q

Eya2, a Target Activated by Plzf, Is Critical for
Molecular and cellular biology37(13)(2017 Jul)
Ono R,Masuya M,Ishii S,Katayama N,Nosaka T

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EYA2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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