U2AF1L4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	U2AF1L4
Entrez Gene ID	199746
Full Name	U2 small nuclear RNA auxiliary factor 1 like 4
Synonyms	U2AF1-RS3,U2AF1L3,U2AF1L3V1,U2AF1RS3,U2af26
General protein information	Preferred Names U2 small nuclear RNA auxiliary factor 1 like 4 Names splicing factor U2AF 26 kDa subunit U2 auxiliary factor 26 U2 small nuclear RNA auxiliary factor 1-like 3 U2 small nuclear RNA auxiliary factor 1-like protein 3 U2 small nuclear RNA auxiliary factor 1-like protein 4 U2(RNU2) small nuclear RNA auxiliary factor 1-like 3 U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3 U2AF1-like 4 U2AF1-like protein 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.12
Disorder MIM:	601080

mRNA and Protein(s)

mRNA	Protein	Name
NM_001040425.2	NP_001035515.1	splicing factor U2AF 26 kDa subunit isoform 1
NM_144987.3	NP_659424.2	splicing factor U2AF 26 kDa subunit isoform 2
NM_144987.4	NP_659424.2	splicing factor U2AF 26 kDa subunit isoform 2
NM_001369824.2	NP_001356753.1	splicing factor U2AF 26 kDa subunit isoform 3
NM_001040425.3	NP_001035515.1	splicing factor U2AF 26 kDa subunit isoform 1

Pathways from BioSystems

Homologies

	LOC718865	XP_001112161.2
Homo sapiens (human)	U2AF1L4	NP_001035515.1
Pan troglodytes (chimpanzee)	U2AF1L4	XP_001160959.1

Gene Ontology
Bibliography

Related articles in PubMed

[Cytokine-mediated regulation of expression of Gfi1 and U2afll4 genes activated by T-cells with different differentiation status in vitro].
Yurova KA, Sokhonevich NA, Khaziakhmatova OG, Litvinova LS
Biomeditsinskaia khimiia62(2)180-6(2016 Mar-Apr)

Human PSENEN and U2AF1L4 genes are concertedly regulated by a genuine bidirectional promoter.
Didych DA, Shamsutdinov MF, Smirnov NA, Akopov SB, Monastyrskaya GS, Uspenskaya NY, Nikolaev LG, Sverdlov ED
Gene515(1)34-41(2013 Feb)

Functional dissection of an enhancer-like element located within the second intron of the human U2AF1L4 gene.
Didych DA, Smirnov NA, Kotova ES, Akopov SB, Nikolaev LG, Sverdlov ED
Biochemistry. Biokhimiia76(8)951-7(2011 Aug)

Differential isoform expression and interaction with the P32 regulatory protein controls the subcellular localization of the splicing factor U2AF26.
Heyd F, Carmo-Fonseca M, M?r?y T
The Journal of biological chemistry283(28)19636-45(2008 Jul)

Characterization of U2AF(6), a splicing factor related to U2AF(35).
Shepard J, Reick M, Olson S, Graveley BR
Molecular and cellular biology22(1)221-30(2002 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

U2AF1L4 gene expression is regulated by cytokines in activated T cells.
Title: [Cytokine-mediated regulation of expression of Gfi1 and U2afll4 genes activated by T-cells with different differentiation status in vitro].

a 269 bp region located between the PSENEN and U2AF1L4 human genes is a genuine bidirectional promoter regulating a concerted divergent transcription of these genes.
Title: Human PSENEN and U2AF1L4 genes are concertedly regulated by a genuine bidirectional promoter.

One of the conservative regions is responsible for the enhancer activity and is able to interact with proteins of HeLa cell nuclear extract.
Title: Functional dissection of an enhancer-like element located within the second intron of the human U2AF1L4 gene.

Differential isoform expression and interaction with the P32 regulatory protein controls the subcellular localization of the splicing factor U2AF26
Title: Differential isoform expression and interaction with the P32 regulatory protein controls the subcellular localization of the splicing factor U2AF26.

The following U2AF1L4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the U2AF1L4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06427	NM_144987.4 Latest version!	Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu04958	NM_001040425.3 Latest version!	Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu108234	NM_001369824.2 Latest version!	Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu06427	NM_144987.3	Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu04958	NM_001040425.2	Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

U2AF1L4 ( NM_144987.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_659424.2 Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu06427
Clone ID Related Accession (Same CDS sequence)	NM_144987.3 , NM_144987.4
Accession Version	NM_144987.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 609bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	splicing factor U2AF 26 kDa subunit isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC415103.1, AY569437.3, BC021186.1, BC010865.1 and AI767079.1. On Jan 7, 2014 this sequence version replaced NM_144987.2. Transcript Variant: This variant (2) encodes the longer isoform (2). ##Evidence-Data-START## Transcript exon combination :: CD175846.1, BC021186.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2153733 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAT ATTTAGCTTC GATATTCGGG ACTGAGAAGG ACAAGGTTAA CTGCTCTTTT 
TACTTTAAGA TCGGGGTCTG CCGGCACGGG GACCGGTGCT CCCGGCTTCA CAACAAGCCG 
ACATTCAGCC AGGAGGTGTT CACAGAACTG CAGGAGAAGT ATGGGGAGAT TGAAGAGATG 
AATGTGTGCG ACAACCTTGG GGACCACCTC GTGGGCAACG TCTATGTCAA GTTCCGGAGG 
GAGGAGGATG GAGAGCGGGC CGTGGCTGAA CTCAGTAACC GCTGGTTCAA CGGGCAGGCT 
GTGCACGGGA ATGTACCCGA GGTGGCTTCT GCAACTTCAT GCATCTGCGG CCCATTTCCC 
AGAACCTCCA GAGGCAGCTC TATGGGCGGG GACCCAGGCG CAGGTCACCC CCGAGGTTCC 
ATACTGGCCA CCATCCCCGA GAGAGGAACC ATCGGTGTTC CCCTGATCAC TGGCATGGCC 
GCTTCTGAGG CCCTGGCCCC CTTACCCTTC ACCCCCAACA GGGACAGATG TTCCTGGCAG 
GACCTCTCCT CAAAGCCCCC TTCACTCTCC TGCCCCATCC TTCCCAGGCT CCCGGGCTCC 
ATAATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659424.2
CDS	52..660
Translation	MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQEVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRREEDGERAVAELSNRWFNGQAVHGNVPEVASATSCICGPFPRTSRGSSMGGDPGAGHPRGSILATIPERGTIGVPLITGMAASEALAPLPFTPNRDRCSWQDLSSKPPSLSCPILPRLPGSIM

Target ORF information:

RefSeq Version	NM_144987.3
Organism	Homo sapiens(human)
Definition	Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144987.3

ORF Insert Sequence:

ATGGCTGAAT ATTTAGCTTC GATATTCGGG ACTGAGAAGG ACAAGGTTAA CTGCTCTTTT 
TACTTTAAGA TCGGGGTCTG CCGGCACGGG GACCGGTGCT CCCGGCTTCA CAACAAGCCG 
ACATTCAGCC AGGAGGTGTT CACAGAACTG CAGGAGAAGT ATGGGGAGAT TGAAGAGATG 
AATGTGTGCG ACAACCTTGG GGACCACCTC GTGGGCAACG TCTATGTCAA GTTCCGGAGG 
GAGGAGGATG GAGAGCGGGC CGTGGCTGAA CTCAGTAACC GCTGGTTCAA CGGGCAGGCT 
GTGCACGGGA ATGTACCCGA GGTGGCTTCT GCAACTTCAT GCATCTGCGG CCCATTTCCC 
AGAACCTCCA GAGGCAGCTC TATGGGCGGG GACCCAGGCG CAGGTCACCC CCGAGGTTCC 
ATACTGGCCA CCATCCCCGA GAGAGGAACC ATCGGTGTTC CCCTGATCAC TGGCATGGCC 
GCTTCTGAGG CCCTGGCCCC CTTACCCTTC ACCCCCAACA GGGACAGATG TTCCTGGCAG 
GACCTCTCCT CAAAGCCCCC TTCACTCTCC TGCCCCATCC TTCCCAGGCT CCCGGGCTCC 
ATAATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

U2AF1L4 ( NM_144987.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_659424.2 Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu06427
Clone ID Related Accession (Same CDS sequence)	NM_144987.3 , NM_144987.4
Accession Version	NM_144987.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 609bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	splicing factor U2AF 26 kDa subunit isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC415103.1, AY569437.3, BC021186.1, BC010865.1 and AI767079.1. On Jun 1, 2019 this sequence version replaced NM_144987.3. Transcript Variant: This variant (2) encodes the longer isoform (2). ##Evidence-Data-START## Transcript exon combination :: SRR5189667.252151.1, ERR279840.6413.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2153733 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAT ATTTAGCTTC GATATTCGGG ACTGAGAAGG ACAAGGTTAA CTGCTCTTTT 
TACTTTAAGA TCGGGGTCTG CCGGCACGGG GACCGGTGCT CCCGGCTTCA CAACAAGCCG 
ACATTCAGCC AGGAGGTGTT CACAGAACTG CAGGAGAAGT ATGGGGAGAT TGAAGAGATG 
AATGTGTGCG ACAACCTTGG GGACCACCTC GTGGGCAACG TCTATGTCAA GTTCCGGAGG 
GAGGAGGATG GAGAGCGGGC CGTGGCTGAA CTCAGTAACC GCTGGTTCAA CGGGCAGGCT 
GTGCACGGGA ATGTACCCGA GGTGGCTTCT GCAACTTCAT GCATCTGCGG CCCATTTCCC 
AGAACCTCCA GAGGCAGCTC TATGGGCGGG GACCCAGGCG CAGGTCACCC CCGAGGTTCC 
ATACTGGCCA CCATCCCCGA GAGAGGAACC ATCGGTGTTC CCCTGATCAC TGGCATGGCC 
GCTTCTGAGG CCCTGGCCCC CTTACCCTTC ACCCCCAACA GGGACAGATG TTCCTGGCAG 
GACCTCTCCT CAAAGCCCCC TTCACTCTCC TGCCCCATCC TTCCCAGGCT CCCGGGCTCC 
ATAATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659424.2
CDS	28..636
Translation	MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQEVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRREEDGERAVAELSNRWFNGQAVHGNVPEVASATSCICGPFPRTSRGSSMGGDPGAGHPRGSILATIPERGTIGVPLITGMAASEALAPLPFTPNRDRCSWQDLSSKPPSLSCPILPRLPGSIM

Target ORF information:

RefSeq Version	NM_144987.4
Organism	Homo sapiens(human)
Definition	Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144987.4

ORF Insert Sequence:

ATGGCTGAAT ATTTAGCTTC GATATTCGGG ACTGAGAAGG ACAAGGTTAA CTGCTCTTTT 
TACTTTAAGA TCGGGGTCTG CCGGCACGGG GACCGGTGCT CCCGGCTTCA CAACAAGCCG 
ACATTCAGCC AGGAGGTGTT CACAGAACTG CAGGAGAAGT ATGGGGAGAT TGAAGAGATG 
AATGTGTGCG ACAACCTTGG GGACCACCTC GTGGGCAACG TCTATGTCAA GTTCCGGAGG 
GAGGAGGATG GAGAGCGGGC CGTGGCTGAA CTCAGTAACC GCTGGTTCAA CGGGCAGGCT 
GTGCACGGGA ATGTACCCGA GGTGGCTTCT GCAACTTCAT GCATCTGCGG CCCATTTCCC 
AGAACCTCCA GAGGCAGCTC TATGGGCGGG GACCCAGGCG CAGGTCACCC CCGAGGTTCC 
ATACTGGCCA CCATCCCCGA GAGAGGAACC ATCGGTGTTC CCCTGATCAC TGGCATGGCC 
GCTTCTGAGG CCCTGGCCCC CTTACCCTTC ACCCCCAACA GGGACAGATG TTCCTGGCAG 
GACCTCTCCT CAAAGCCCCC TTCACTCTCC TGCCCCATCC TTCCCAGGCT CCCGGGCTCC 
ATAATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

U2AF1L4 ( NM_001040425.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001035515.1 Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04958
Clone ID Related Accession (Same CDS sequence)	NM_001040425.2 , NM_001040425.3
Accession Version	NM_001040425.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	splicing factor U2AF 26 kDa subunit isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC415103.1, AY569437.3 and AI767079.1. On Jan 7, 2014 this sequence version replaced NM_001040425.1. Transcript Variant: This variant (1) has an alternate splice site in the coding region, which results in reading frameshift, compared to variant 2. The resulting isoform (1) is shorter and has a distinct C-terminus, compared to isoform 2. ##Evidence-Data-START## Transcript exon combination :: AY569437.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2153733 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAT ATTTAGCTTC GATATTCGGG ACTGAGAAGG ACAAGGTTAA CTGCTCTTTT 
TACTTTAAGA TCGGGGTCTG CCGGCACGGG GACCGGTGCT CCCGGCTTCA CAACAAGCCG 
ACATTCAGCC AGGAGGTGTT CACAGAACTG CAGGAGAAGT ATGGGGAGAT TGAAGAGATG 
AATGTGTGCG ACAACCTTGG GGACCACCTC GTGGGCAACG TCTATGTCAA GTTCCGGAGG 
GAGGAGGATG GAGAGCGGGC CGTGGCTGAA CTCAGTAACC GCTGGTTCAA CGGGCAGGCT 
GTGCACGGTG AGCTGTCTCC TGTCACTGAC TTCCGGGAGT CATGCTGTCG CCAGTATGAG 
ATGGGGGAAT GTACCCGAGG TGGCTTCTGC AACTTCATGC ATCTGCGGCC CATTTCCCAG 
AACCTCCAGA GGCAGCTCTA TGGGCGGGGA CCCAGGCGCA GGTCACCCCC GAGGTTCCAT 
ACTGGCCACC ATCCCCGAGA GAGGAACCAT CGGTGTTCCC CTGATCACTG GCATGGCCGC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035515.1
CDS	52..597
Translation	MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQEVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRREEDGERAVAELSNRWFNGQAVHGELSPVTDFRESCCRQYEMGECTRGGFCNFMHLRPISQNLQRQLYGRGPRRRSPPRFHTGHHPRERNHRCSPDHWHGRF

Target ORF information:

RefSeq Version	NM_001040425.2
Organism	Homo sapiens(human)
Definition	Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040425.2

ORF Insert Sequence:

ATGGCTGAAT ATTTAGCTTC GATATTCGGG ACTGAGAAGG ACAAGGTTAA CTGCTCTTTT 
TACTTTAAGA TCGGGGTCTG CCGGCACGGG GACCGGTGCT CCCGGCTTCA CAACAAGCCG 
ACATTCAGCC AGGAGGTGTT CACAGAACTG CAGGAGAAGT ATGGGGAGAT TGAAGAGATG 
AATGTGTGCG ACAACCTTGG GGACCACCTC GTGGGCAACG TCTATGTCAA GTTCCGGAGG 
GAGGAGGATG GAGAGCGGGC CGTGGCTGAA CTCAGTAACC GCTGGTTCAA CGGGCAGGCT 
GTGCACGGTG AGCTGTCTCC TGTCACTGAC TTCCGGGAGT CATGCTGTCG CCAGTATGAG 
ATGGGGGAAT GTACCCGAGG TGGCTTCTGC AACTTCATGC ATCTGCGGCC CATTTCCCAG 
AACCTCCAGA GGCAGCTCTA TGGGCGGGGA CCCAGGCGCA GGTCACCCCC GAGGTTCCAT 
ACTGGCCACC ATCCCCGAGA GAGGAACCAT CGGTGTTCCC CTGATCACTG GCATGGCCGC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

U2AF1L4 ( NM_001040425.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001035515.1 Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04958
Clone ID Related Accession (Same CDS sequence)	NM_001040425.2 , NM_001040425.3
Accession Version	NM_001040425.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	splicing factor U2AF 26 kDa subunit isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC415103.1, AY569437.3 and AI767079.1. On Nov 22, 2018 this sequence version replaced NM_001040425.2. Transcript Variant: This variant (1) has an alternate splice site in the coding region, which results in reading frameshift, compared to variant 2. The resulting isoform (1) is shorter and has a distinct C-terminus, compared to isoform 2. ##Evidence-Data-START## Transcript exon combination :: AY569437.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2153733 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000378975.8/ ENSP00000368258.2 RefSeq Select criteria :: based on conservation ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTGAAT ATTTAGCTTC GATATTCGGG ACTGAGAAGG ACAAGGTTAA CTGCTCTTTT 
TACTTTAAGA TCGGGGTCTG CCGGCACGGG GACCGGTGCT CCCGGCTTCA CAACAAGCCG 
ACATTCAGCC AGGAGGTGTT CACAGAACTG CAGGAGAAGT ATGGGGAGAT TGAAGAGATG 
AATGTGTGCG ACAACCTTGG GGACCACCTC GTGGGCAACG TCTATGTCAA GTTCCGGAGG 
GAGGAGGATG GAGAGCGGGC CGTGGCTGAA CTCAGTAACC GCTGGTTCAA CGGGCAGGCT 
GTGCACGGTG AGCTGTCTCC TGTCACTGAC TTCCGGGAGT CATGCTGTCG CCAGTATGAG 
ATGGGGGAAT GTACCCGAGG TGGCTTCTGC AACTTCATGC ATCTGCGGCC CATTTCCCAG 
AACCTCCAGA GGCAGCTCTA TGGGCGGGGA CCCAGGCGCA GGTCACCCCC GAGGTTCCAT 
ACTGGCCACC ATCCCCGAGA GAGGAACCAT CGGTGTTCCC CTGATCACTG GCATGGCCGC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035515.1
CDS	28..573
Translation	MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQEVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRREEDGERAVAELSNRWFNGQAVHGELSPVTDFRESCCRQYEMGECTRGGFCNFMHLRPISQNLQRQLYGRGPRRRSPPRFHTGHHPRERNHRCSPDHWHGRF

Target ORF information:

RefSeq Version	NM_001040425.3
Organism	Homo sapiens(human)
Definition	Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040425.3

ORF Insert Sequence:

ATGGCTGAAT ATTTAGCTTC GATATTCGGG ACTGAGAAGG ACAAGGTTAA CTGCTCTTTT 
TACTTTAAGA TCGGGGTCTG CCGGCACGGG GACCGGTGCT CCCGGCTTCA CAACAAGCCG 
ACATTCAGCC AGGAGGTGTT CACAGAACTG CAGGAGAAGT ATGGGGAGAT TGAAGAGATG 
AATGTGTGCG ACAACCTTGG GGACCACCTC GTGGGCAACG TCTATGTCAA GTTCCGGAGG 
GAGGAGGATG GAGAGCGGGC CGTGGCTGAA CTCAGTAACC GCTGGTTCAA CGGGCAGGCT 
GTGCACGGTG AGCTGTCTCC TGTCACTGAC TTCCGGGAGT CATGCTGTCG CCAGTATGAG 
ATGGGGGAAT GTACCCGAGG TGGCTTCTGC AACTTCATGC ATCTGCGGCC CATTTCCCAG 
AACCTCCAGA GGCAGCTCTA TGGGCGGGGA CCCAGGCGCA GGTCACCCCC GAGGTTCCAT 
ACTGGCCACC ATCCCCGAGA GAGGAACCAT CGGTGTTCCC CTGATCACTG GCATGGCCGC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

U2AF1L4 ( NM_001369824.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001356753.1 Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu108234
Clone ID Related Accession (Same CDS sequence)	NM_001369824.2
Accession Version	NM_001369824.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 420bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	splicing factor U2AF 26 kDa subunit isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AD000671.1. On May 31, 2019 this sequence version replaced NM_001369824.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7410570.653578.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCTGAAT ATTTAGCTTC GATATTCGGG ACTGAGAAGG ACAAGGTTAA CTGCTCTTTT 
TACTTTAAGA TCGGGGTCTG CCGGCACGGG GACCGGTGCT CCCGGCTTCA CAACAAGCCG 
ACATTCAGCC AGGAGGTGTT CACAGAACTG CAGGAGAAGT ATGGGGAGAT TGAAGAGATG 
AATGTGTGCG ACAACCTTGG GGACCACCTC GTGGGCAACG TCTATGTCAA GTTCCGGAGG 
GAGGAGGATG GAGAGCGGGC CGTGGCTGAA CTCAGTAACC GCTGGTTCAA CGGGCAGGCT 
GTGCACGGGA ATGTACCCGA GGTGGCTTCT GCAACTTCAT GCATCTGCGG CCCATTTCCC 
AGAACCTCCA GAGGCAGCTC TATGGGCGGG GACCCAGGCG CAGGCTCCCG GGCTCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001356753.1
CDS	28..447
Translation	MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQEVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRREEDGERAVAELSNRWFNGQAVHGNVPEVASATSCICGPFPRTSRGSSMGGDPGAGSRAP

Target ORF information:

RefSeq Version	NM_001369824.2
Organism	Homo sapiens(human)
Definition	Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001369824.2

ORF Insert Sequence:

ATGGCTGAAT ATTTAGCTTC GATATTCGGG ACTGAGAAGG ACAAGGTTAA CTGCTCTTTT 
TACTTTAAGA TCGGGGTCTG CCGGCACGGG GACCGGTGCT CCCGGCTTCA CAACAAGCCG 
ACATTCAGCC AGGAGGTGTT CACAGAACTG CAGGAGAAGT ATGGGGAGAT TGAAGAGATG 
AATGTGTGCG ACAACCTTGG GGACCACCTC GTGGGCAACG TCTATGTCAA GTTCCGGAGG 
GAGGAGGATG GAGAGCGGGC CGTGGCTGAA CTCAGTAACC GCTGGTTCAA CGGGCAGGCT 
GTGCACGGGA ATGTACCCGA GGTGGCTTCT GCAACTTCAT GCATCTGCGG CCCATTTCCC 
AGAACCTCCA GAGGCAGCTC TATGGGCGGG GACCCAGGCG CAGGCTCCCG GGCTCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

[Cytokine-mediated regulation of expression of Gfi1 and U2afll4 genes activated by T-cells with different differentiation status in vitro].
Biomeditsinskaia khimiia62(2)180-6(2016 Mar-Apr)
Yurova KA,Sokhonevich NA,Khaziakhmatova OG,Litvinova LS

Human PSENEN and U2AF1L4 genes are concertedly regulated by a genuine bidirectional promoter.
Gene515(1)34-41(2013 Feb)
Didych DA,Shamsutdinov MF,Smirnov NA,Akopov SB,Monastyrskaya GS,Uspenskaya NY,Nikolaev LG,Sverdlov ED

Functional dissection of an enhancer-like element located within the second intron of the human U2AF1L4 gene.
Biochemistry. Biokhimiia76(8)951-7(2011 Aug)
Didych DA,Smirnov NA,Kotova ES,Akopov SB,Nikolaev LG,Sverdlov ED

Differential isoform expression and interaction with the P32 regulatory protein controls the subcellular localization of the splicing factor U2AF26.
The Journal of biological chemistry283(28)19636-45(2008 Jul)
Heyd F,Carmo-Fonseca M,M?r?y T

Characterization of U2AF(6), a splicing factor related to U2AF(35).
Molecular and cellular biology22(1)221-30(2002 Jan)
Shepard J,Reick M,Olson S,Graveley BR

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U2AF1L4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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