| Gene Symbol | DDOST |
| Entrez Gene ID | 1650 |
| Full Name | dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit |
| Synonyms | AGER1,CDG1R,GATD6,OKSWcl45,OST,OST48,WBP1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]. |
| Disorder MIM: | |
| Disorder Html: | ?Congenital disorder of glycosylation, type Ir, 614507 (3) |









































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