DDOST cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DDOST
Entrez Gene ID	1650
Full Name	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
Synonyms	AGER1,CDG1R,GATD6,OKSWcl45,OST,OST48,WBP1
General protein information	Preferred Names dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit Names dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit advanced glycation end-product receptor 1 advanced glycation endproduct receptor 1 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) dolichyl-diphosphooligosaccharide-protein glycotransferase oligosaccharyl transferase 48 kDa subunit oligosaccharyltransferase 48 kDa subunit oligosaccharyltransferase subunit 48
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.12
Summary	This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008].
Disorder MIM:	602202
Disorder Html:	?Congenital disorder of glycosylation, type Ir, 614507 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_005216.5	NP_005207.3	dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor
NM_005216.4	NP_005207.2	dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DDOST	XP_001161661.1
	LOC718760	XP_001111903.1
Drosophila melanogaster (fruit fly)	Ost48	NP_511096.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006383	XP_316417.4
Homo sapiens (human)	DDOST	NP_005207.2
Xenopus tropicalis (tropical clawed frog)	ddost	NP_001120481.1
Danio rerio (zebrafish)	ddost	NP_998258.1
Mus musculus (house mouse)	Ddost	NP_031864.2
Rattus norvegicus (Norway rat)	Ddost	NP_001012104.1
Oryza sativa (rice)	Os07g0209000	NP_001059165.1
Canis lupus familiaris (dog)	DDOST	NP_001003321.1
Bos taurus (cattle)	DDOST	NP_001094543.1
Gallus gallus (chicken)	DDOST	NP_001161480.1
Caenorhabditis elegans (roundworm)	ostb-1	NP_495655.1
Arabidopsis thaliana (thale cress)	DGL1	NP_569038.1

Gene Ontology
Bibliography

Related articles in PubMed

Dietary advanced glycated end-products and medicines influence the expression of SIRT1 and DDOST in peripheral mononuclear cells from long-term type 1 diabetes patients.
Santos-Bezerra DP, Machado-Lima A, Monteiro MB, Admoni SN, Perez RV, Machado CG, Shimizu MH, Cavaleiro AM, Thieme K, Queiroz MS, Machado UF, Giannella-Neto D, Passarelli M, Corr?a-Giannella ML
Diabetes & vascular disease research15(1)81-89(2018 Jan)

Increased liver AGEs induce hepatic injury mediated through an OST48 pathway.
Zhuang A, Yap FY, Bruce C, Leung C, Plan MR, Sullivan MA, Herath C, McCarthy D, Sourris KC, Kantharidis P, Coughlan MT, Febbraio MA, Hodson MP, Watt MJ, Angus P, Schulz BL, Forbes JM
Scientific reports7(1)12292(2017 Sep)

Mitotic Phosphorylation of TREX1 C Terminus Disrupts TREX1 Regulation of the Oligosaccharyltransferase Complex.
Kucej M, Fermaintt CS, Yang K, Irizarry-Caro RA, Yan N
Cell reports18(11)2600-2607(2017 Mar)

DDOST mutations identified by whole-exome sequencing are implicated in congenital disorders of glycosylation.
Jones MA, Ng BG, Bhide S, Chin E, Rhodenizer D, He P, Losfeld ME, He M, Raymond K, Berry G, Freeze HH, Hegde MR
American journal of human genetics90(2)363-8(2012 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

DDOST and SIRT1 are differently expressed in peripheral blood mononuclear cells from type 1 diabetes patients with and without microvascular complications. Their expression is also influenced by dietary advanced glycation end-products and by statins and angiotensin receptor blockers.
Title: Dietary advanced glycated end-products and medicines influence the expression of SIRT1 and DDOST in peripheral mononuclear cells from long-term type 1 diabetes patients.

the cell-cycle-dependent post-translation modification of TREX1 regulates its interaction with OST.
Title: Mitotic Phosphorylation of TREX1 C Terminus Disrupts TREX1 Regulation of the Oligosaccharyltransferase Complex.

Found a 22 bp deletion and a missense mutation in DDOST.
Title: DDOST mutations identified by whole-exome sequencing are implicated in congenital disorders of glycosylation.

Observational study of gene-disease association. (HuGE Navigator)
Title: DDOST, PRKCSH and LGALS3, which encode AGE-receptors 1, 2 and 3, respectively, are not associated with diabetic nephropathy in type 1 diabetes.

AGER1 provides protection against AGE-induced reactive oxygen species generation via NADPH oxidase and protein kinase C delta.
Title: AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease.

The following DDOST gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DDOST cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu19081	NM_005216.4 Latest version!	Homo sapiens dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit (DDOST), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu109347	NM_005216.5 Latest version!	Homo sapiens dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit (DDOST), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DDOST ( NM_005216.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005207.2 Homo sapiens dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit (DDOST), mRNA.

Price & Availability↑

CloneID	OHu19081
Clone ID Related Accession (Same CDS sequence)	NM_005216.4
Accession Version	NM_005216.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP233191.1, CB988524.1, BC002594.2, AL391357.20 and CB137813.1. This sequence is a reference standard in the RefSeqGene project. On Aug 16, 2006 this sequence version replaced NM_005216.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.16916.1, BC002594.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093, SAMEA2158569 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGTACT TCCGGTGTGC AGGTGCTGGG TCCTTCGGCA GGAGGAGGAA GATGGAGCCC 
AGCACCGCGG CCCGGGCTTG GGCCCTCTTT TGGTTGCTGC TGCCCTTGCT TGGCGCGGTT 
TGCGCCAGCG GACCCCGCAC CTTAGTGCTG CTGGACAACC TCAACGTGCG GGAGACTCAT 
TCGCTTTTCT TCCGGAGCCT GAAGGACCGG GGCTTTGAGC TCACATTCAA GACCGCTGAT 
GACCCCAGCC TGTCTCTCAT AAAGTATGGG GAATTCCTCT ATGACAATCT CATCATTTTC 
TCCCCTTCGG TAGAAGATTT TGGAGGCAAC ATCAACGTGG AGACCATCAG TGCCTTTATT 
GACGGCGGAG GCAGTGTGCT GGTAGCTGCC AGCTCCGACA TTGGTGACCC TCTTCGAGAG 
CTGGGCAGTG AGTGCGGGAT TGAGTTTGAC GAGGAGAAAA CGGCTGTCAT TGACCATCAC 
AACTATGACA TCTCAGACCT TGGCCAGCAT ACGCTCATCG TGGCTGACAC TGAGAACCTG 
CTGAAGGCCC CAACCATCGT TGGGAAATCA TCTCTAAATC CCATCCTCTT TCGAGGTGTT 
GGGATGGTGG CCGATCCTGA TAACCCTTTG GTGCTGGACA TCCTGACGGG CTCTTCCACC 
TCTTACTCCT TCTTCCCGGA CAAGCCTATC ACCCAGTATC CACATGCGGT GGGGAAGAAC 
ACCCTCCTCA TTGCTGGGCT CCAGGCCAGG AACAATGCCC GCGTCATCTT CAGCGGCTCC 
CTCGACTTCT TCAGCGACTC CTTCTTCAAC TCAGCAGTGC AGAAGGCGGC GCCCGGCTCC 
CAGAGGTATT CCCAGACAGG CAACTATGAA CTAGCTGTGG CCCTCTCCCG CTGGGTGTTC 
AAGGAGGAGG GTGTCCTCCG TGTGGGGCCT GTGTCCCATC ATCGGGTGGG CGAGACAGCC 
CCACCCAATG CCTACACTGT CACTGACCTA GTGGAGTATA GCATCGTGAT CCAGCAGCTC 
TCAAATGGCA AATGGGTCCC CTTTGATGGC GATGACATTC AGCTGGAGTT TGTCCGCATT 
GATCCTTTTG TGAGGACCTT CCTGAAGAAG AAAGGTGGCA AATACAGTGT TCAGTTCAAG 
TTGCCCGACG TGTATGGTGT ATTCCAGTTT AAAGTGGATT ACAACCGGCT AGGCTACACA 
CACCTGTACT CTTCCACTCA GGTATCCGTG CGGCCACTCC AGCACACGCA GTATGAGCGC 
TTCATCCCCT CGGCCTACCC CTACTACGCC AGCGCCTTCT CCATGATGCT GGGGCTCTTC 
ATCTTCAGCA TCGTCTTCTT GCACATGAAG GAGAAGGAGA AGTCCGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005207.2
CDS	144..1514
Translation	MGYFRCAGAGSFGRRRKMEPSTAARAWALFWLLLPLLGAVCASGPRTLVLLDNLNVRETHSLFFRSLKDRGFELTFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDLGQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDSFFNSAVQKAAPGSQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPNAYTVTDLVEYSIVIQQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKKKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMLGLFIFSIVFLHMKEKEKSD

Target ORF information:

RefSeq Version	NM_005216.4
Organism	Homo sapiens(human)
Definition	Homo sapiens dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit (DDOST), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005216.4

ORF Insert Sequence:

ATGGGGTACT TCCGGTGTGC AGGTGCTGGG TCCTTCGGCA GGAGGAGGAA GATGGAGCCC 
AGCACCGCGG CCCGGGCTTG GGCCCTCTTT TGGTTGCTGC TGCCCTTGCT TGGCGCGGTT 
TGCGCCAGCG GACCCCGCAC CTTAGTGCTG CTGGACAACC TCAACGTGCG GGAGACTCAT 
TCGCTTTTCT TCCGGAGCCT GAAGGACCGG GGCTTTGAGC TCACATTCAA GACCGCTGAT 
GACCCCAGCC TGTCTCTCAT AAAGTATGGG GAATTCCTCT ATGACAATCT CATCATTTTC 
TCCCCTTCGG TAGAAGATTT TGGAGGCAAC ATCAACGTGG AGACCATCAG TGCCTTTATT 
GACGGCGGAG GCAGTGTGCT GGTAGCTGCC AGCTCCGACA TTGGTGACCC TCTTCGAGAG 
CTGGGCAGTG AGTGCGGGAT TGAGTTTGAC GAGGAGAAAA CGGCTGTCAT TGACCATCAC 
AACTATGACA TCTCAGACCT TGGCCAGCAT ACGCTCATCG TGGCTGACAC TGAGAACCTG 
CTGAAGGCCC CAACCATCGT TGGGAAATCA TCTCTAAATC CCATCCTCTT TCGAGGTGTT 
GGGATGGTGG CCGATCCTGA TAACCCTTTG GTGCTGGACA TCCTGACGGG CTCTTCCACC 
TCTTACTCCT TCTTCCCGGA CAAGCCTATC ACCCAGTATC CACATGCGGT GGGGAAGAAC 
ACCCTCCTCA TTGCTGGGCT CCAGGCCAGG AACAATGCCC GCGTCATCTT CAGCGGCTCC 
CTCGACTTCT TCAGCGACTC CTTCTTCAAC TCAGCAGTGC AGAAGGCGGC GCCCGGCTCC 
CAGAGGTATT CCCAGACAGG CAACTATGAA CTAGCTGTGG CCCTCTCCCG CTGGGTGTTC 
AAGGAGGAGG GTGTCCTCCG TGTGGGGCCT GTGTCCCATC ATCGGGTGGG CGAGACAGCC 
CCACCCAATG CCTACACTGT CACTGACCTA GTGGAGTATA GCATCGTGAT CCAGCAGCTC 
TCAAATGGCA AATGGGTCCC CTTTGATGGC GATGACATTC AGCTGGAGTT TGTCCGCATT 
GATCCTTTTG TGAGGACCTT CCTGAAGAAG AAAGGTGGCA AATACAGTGT TCAGTTCAAG 
TTGCCCGACG TGTATGGTGT ATTCCAGTTT AAAGTGGATT ACAACCGGCT AGGCTACACA 
CACCTGTACT CTTCCACTCA GGTATCCGTG CGGCCACTCC AGCACACGCA GTATGAGCGC 
TTCATCCCCT CGGCCTACCC CTACTACGCC AGCGCCTTCT CCATGATGCT GGGGCTCTTC 
ATCTTCAGCA TCGTCTTCTT GCACATGAAG GAGAAGGAGA AGTCCGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DDOST ( NM_005216.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005207.3 Homo sapiens dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit (DDOST), mRNA.

Price & Availability↑

CloneID	OHu109347
Clone ID Related Accession (Same CDS sequence)	NM_005216.5
Accession Version	NM_005216.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1320bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC002594.2, AB062391.1 and AL391357.20. On Sep 27, 2019 this sequence version replaced NM_005216.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCCA GCACCGCGGC CCGGGCTTGG GCCCTCTTTT GGTTGCTGCT GCCCTTGCTT 
GGCGCGGTTT GCGCCAGCGG ACCCCGCACC TTAGTGCTGC TGGACAACCT CAACGTGCGG 
GAGACTCATT CGCTTTTCTT CCGGAGCCTG AAGGACCGGG GCTTTGAGCT CACATTCAAG 
ACCGCTGATG ACCCCAGCCT GTCTCTCATA AAGTATGGGG AATTCCTCTA TGACAATCTC 
ATCATTTTCT CCCCTTCGGT AGAAGATTTT GGAGGCAACA TCAACGTGGA GACCATCAGT 
GCCTTTATTG ACGGCGGAGG CAGTGTGCTG GTAGCTGCCA GCTCCGACAT TGGTGACCCT 
CTTCGAGAGC TGGGCAGTGA GTGCGGGATT GAGTTTGACG AGGAGAAAAC GGCTGTCATT 
GACCATCACA ACTATGACAT CTCAGACCTT GGCCAGCATA CGCTCATCGT GGCTGACACT 
GAGAACCTGC TGAAGGCCCC AACCATCGTT GGGAAATCAT CTCTAAATCC CATCCTCTTT 
CGAGGTGTTG GGATGGTGGC CGATCCTGAT AACCCTTTGG TGCTGGACAT CCTGACGGGC 
TCTTCCACCT CTTACTCCTT CTTCCCGGAC AAGCCTATCA CCCAGTATCC ACATGCGGTG 
GGGAAGAACA CCCTCCTCAT TGCTGGGCTC CAGGCCAGGA ACAATGCCCG CGTCATCTTC 
AGCGGCTCCC TCGACTTCTT CAGCGACTCC TTCTTCAACT CAGCAGTGCA GAAGGCGGCG 
CCCGGCTCCC AGAGGTATTC CCAGACAGGC AACTATGAAC TAGCTGTGGC CCTCTCCCGC 
TGGGTGTTCA AGGAGGAGGG TGTCCTCCGT GTGGGGCCTG TGTCCCATCA TCGGGTGGGC 
GAGACAGCCC CACCCAATGC CTACACTGTC ACTGACCTAG TGGAGTATAG CATCGTGATC 
CAGCAGCTCT CAAATGGCAA ATGGGTCCCC TTTGATGGCG ATGACATTCA GCTGGAGTTT 
GTCCGCATTG ATCCTTTTGT GAGGACCTTC CTGAAGAAGA AAGGTGGCAA ATACAGTGTT 
CAGTTCAAGT TGCCCGACGT GTATGGTGTA TTCCAGTTTA AAGTGGATTA CAACCGGCTA 
GGCTACACAC ACCTGTACTC TTCCACTCAG GTATCCGTGC GGCCACTCCA GCACACGCAG 
TATGAGCGCT TCATCCCCTC GGCCTACCCC TACTACGCCA GCGCCTTCTC CATGATGCTG 
GGGCTCTTCA TCTTCAGCAT CGTCTTCTTG CACATGAAGG AGAAGGAGAA GTCCGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005207.3
CDS	20..1339
Translation	MEPSTAARAWALFWLLLPLLGAVCASGPRTLVLLDNLNVRETHSLFFRSLKDRGFELTFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDLGQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDSFFNSAVQKAAPGSQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPNAYTVTDLVEYSIVIQQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKKKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMLGLFIFSIVFLHMKEKEKSD

Target ORF information:

RefSeq Version	NM_005216.5
Organism	Homo sapiens(human)
Definition	Homo sapiens dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit (DDOST), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005216.5

ORF Insert Sequence:

ATGGAGCCCA GCACCGCGGC CCGGGCTTGG GCCCTCTTTT GGTTGCTGCT GCCCTTGCTT 
GGCGCGGTTT GCGCCAGCGG ACCCCGCACC TTAGTGCTGC TGGACAACCT CAACGTGCGG 
GAGACTCATT CGCTTTTCTT CCGGAGCCTG AAGGACCGGG GCTTTGAGCT CACATTCAAG 
ACCGCTGATG ACCCCAGCCT GTCTCTCATA AAGTATGGGG AATTCCTCTA TGACAATCTC 
ATCATTTTCT CCCCTTCGGT AGAAGATTTT GGAGGCAACA TCAACGTGGA GACCATCAGT 
GCCTTTATTG ACGGCGGAGG CAGTGTGCTG GTAGCTGCCA GCTCCGACAT TGGTGACCCT 
CTTCGAGAGC TGGGCAGTGA GTGCGGGATT GAGTTTGACG AGGAGAAAAC GGCTGTCATT 
GACCATCACA ACTATGACAT CTCAGACCTT GGCCAGCATA CGCTCATCGT GGCTGACACT 
GAGAACCTGC TGAAGGCCCC AACCATCGTT GGGAAATCAT CTCTAAATCC CATCCTCTTT 
CGAGGTGTTG GGATGGTGGC CGATCCTGAT AACCCTTTGG TGCTGGACAT CCTGACGGGC 
TCTTCCACCT CTTACTCCTT CTTCCCGGAC AAGCCTATCA CCCAGTATCC ACATGCGGTG 
GGGAAGAACA CCCTCCTCAT TGCTGGGCTC CAGGCCAGGA ACAATGCCCG CGTCATCTTC 
AGCGGCTCCC TCGACTTCTT CAGCGACTCC TTCTTCAACT CAGCAGTGCA GAAGGCGGCG 
CCCGGCTCCC AGAGGTATTC CCAGACAGGC AACTATGAAC TAGCTGTGGC CCTCTCCCGC 
TGGGTGTTCA AGGAGGAGGG TGTCCTCCGT GTGGGGCCTG TGTCCCATCA TCGGGTGGGC 
GAGACAGCCC CACCCAATGC CTACACTGTC ACTGACCTAG TGGAGTATAG CATCGTGATC 
CAGCAGCTCT CAAATGGCAA ATGGGTCCCC TTTGATGGCG ATGACATTCA GCTGGAGTTT 
GTCCGCATTG ATCCTTTTGT GAGGACCTTC CTGAAGAAGA AAGGTGGCAA ATACAGTGTT 
CAGTTCAAGT TGCCCGACGT GTATGGTGTA TTCCAGTTTA AAGTGGATTA CAACCGGCTA 
GGCTACACAC ACCTGTACTC TTCCACTCAG GTATCCGTGC GGCCACTCCA GCACACGCAG 
TATGAGCGCT TCATCCCCTC GGCCTACCCC TACTACGCCA GCGCCTTCTC CATGATGCTG 
GGGCTCTTCA TCTTCAGCAT CGTCTTCTTG CACATGAAGG AGAAGGAGAA GTCCGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dietary advanced glycated end-products and medicines influence the expression of SIRT1 and DDOST in peripheral mononuclear cells from long-term type 1 diabetes patients.
Diabetes & vascular disease research15(1)81-89(2018 Jan)
Santos-Bezerra DP,Machado-Lima A,Monteiro MB,Admoni SN,Perez RV,Machado CG,Shimizu MH,Cavaleiro AM,Thieme K,Queiroz MS,Machado UF,Giannella-Neto D,Passarelli M,Corr?a-Giannella ML

Increased liver AGEs induce hepatic injury mediated through an OST48 pathway.
Scientific reports7(1)12292(2017 Sep)
Zhuang A,Yap FY,Bruce C,Leung C,Plan MR,Sullivan MA,Herath C,McCarthy D,Sourris KC,Kantharidis P,Coughlan MT,Febbraio MA,Hodson MP,Watt MJ,Angus P,Schulz BL,Forbes JM

Mitotic Phosphorylation of TREX1 C Terminus Disrupts TREX1 Regulation of the Oligosaccharyltransferase Complex.
Cell reports18(11)2600-2607(2017 Mar)
Kucej M,Fermaintt CS,Yang K,Irizarry-Caro RA,Yan N

DDOST mutations identified by whole-exome sequencing are implicated in congenital disorders of glycosylation.
American journal of human genetics90(2)363-8(2012 Feb)
Jones MA,Ng BG,Bhide S,Chin E,Rhodenizer D,He P,Losfeld ME,He M,Raymond K,Berry G,Freeze HH,Hegde MR

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

DDOST cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報