DENND2C cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DENND2C
Entrez Gene ID	163259
Full Name	DENN domain containing 2C
Synonyms	dJ1156J9.1
General protein information	Preferred Names DENN domain containing 2C Names DENN domain-containing protein 2C DENN/MADD domain containing 2C RP5-1156J9.1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p13.2

mRNA and Protein(s)

mRNA	Protein	Name
NM_198459.4	NP_940861.3	DENN domain-containing protein 2C isoform 2
NM_001256404.2	NP_001243333.1	DENN domain-containing protein 2C isoform 1
NM_001256404.1	NP_001243333.1	DENN domain-containing protein 2C isoform 1
NM_198459.3	NP_940861.3	DENN domain-containing protein 2C isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DENND2C	XP_524806.2
Bos taurus (cattle)	DENND2C	NP_001179486.1
Homo sapiens (human)	DENND2C	NP_001243333.1
Mus musculus (house mouse)	Dennd2c	NP_808525.2
Gallus gallus (chicken)	DENND2C	NP_001244225.1
Danio rerio (zebrafish)	dennd2c	XP_001919086.4
	DENND2C	XP_002801777.1
Canis lupus familiaris (dog)	DENND2C	XP_005630699.1
Rattus norvegicus (Norway rat)	Dennd2c	NP_001178498.1
Xenopus tropicalis (tropical clawed frog)	dennd2c	NP_001072651.1

Gene Ontology
Bibliography

Related articles in PubMed

Common genetic variants on 1p13.2 associate with risk of autism.
Xia K, Guo H, Hu Z, Xun G, Zuo L, Peng Y, Wang K, He Y, Xiong Z, Sun L, Pan Q, Long Z, Zou X, Li X, Li W, Xu X, Lu L, Liu Y, Hu Y, Tian D, Long L, Ou J, Liu Y, Li X, Zhang L, Pan Y, Chen J, Peng H, Liu Q, Luo X, Su W, Wu L, Liang D, Dai H, Yan X, Feng Y, Tang B, Li J, Miedzybrodzka Z, Xia J, Zhang Z, Luo X, Zhang X, St Clair D, Zhao J, Zhang F
Molecular psychiatry19(11)1212-9(2014 Nov)

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.
Yoshimura S, Gerondopoulos A, Linford A, Rigden DJ, Barr FA
The Journal of cell biology191(2)367-81(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following DENND2C gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DENND2C cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15406	NM_001256404.2 Latest version!	Homo sapiens DENN domain containing 2C (DENND2C), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu15410	NM_198459.4 Latest version!	Homo sapiens DENN domain containing 2C (DENND2C), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$615.30 $879.00
View Old Accession Versions >>
OHu15406	NM_001256404.1	Homo sapiens DENN domain containing 2C (DENND2C), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu15410	NM_198459.3	Homo sapiens DENN domain containing 2C (DENND2C), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$615.30 $879.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DENND2C ( NM_001256404.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243333.1 Homo sapiens DENN domain containing 2C (DENND2C), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15406
Clone ID Related Accession (Same CDS sequence)	NM_001256404.2 , NM_001256404.1
Accession Version	NM_001256404.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2787bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	DENN domain-containing protein 2C isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX647950.1, AL096773.6, AL133382.8 and AL390241.19. On Nov 22, 2018 this sequence version replaced NM_001256404.1. Transcript Variant: This variant (1) represents the longer variant and it encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: CR749576.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000393274.6/ ENSP00000376955.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGATGTTG GTTTTTCTCG TACTACTGTT CAGACACTGT CAAGAAGCCA CTGCAAAAAC 
ATCAAACAAA AAATTTCTCA ATGGGAAGGA AGGGCTAATG GTATATCTAA TCCAGAAAAG 
TGGTGTCCAA AGGACTTTGG AGTGAGATAT AACTGTCACC AAGAGATCCG TCTTAAGAAA 
AATCCTATAG CTGAGAGAAA GAGCAAAAAC TTGGATGTAA CCAGCCGTGA AAATGTGGGT 
CTAGATATAA ATGAAAATAC CAAAAGCCAT GATCAAAGTG AGAATGAAAA TAAGAAACAT 
GAATATGACG ATACACACTT CTTTAAAAAT GAATCAGAAT CCAACTGGGT ATGTTCTCGG 
GTCAAAGAAA TTGAAAGCTG TAAAGAAGAT GTCTTAGATC CAGAGACTTC ATTACCTCCA 
GGAAACTTCT ATACCTCACA AATACTGTGG AAGAAAATAG AAGCACTTCC CCCAGATAAA 
CTCTTAAATT TGGCTTTAGA ACATTGTGAC TCTTCAGAAA AAGAACTGAA CTTCAGAGTT 
CTGGATAGTT CATACGGAAT AACCAAGAGC TTAGAAAATA TTTACTCTGA ACCTGAGGGG 
CAAGAATGTG GACCTTCCAT AAATCCTTTG CCAAAACCTC GTAGGACATT CAGATATTTA 
TCCGAATCTG GTGTTACGCC GTATAAAGAA AGAAACTGTG ACAAAAAATA CTGTGAAAAT 
AACTCTTGTG CACAATCTTC TTTGGCCTCT TCTCAGGAAC CTGAACCAAA GAAATATGGT 
GGAAAAATCA GAGGAAGATC TAAAAGGAAA TCCTTTGAAT TTGAGGATAT TCAGCACTTT 
CGAAATCGGA ACTCACAGAC GATTCGTGAA GAACTTGGAA GAAATTCTGG GTCAGCACTT 
TATTACACAC AGTCTGAGGA CAATATCTAT GAAGATATCA TATATCCCAC CAAAGAAAAT 
CCATATGAAG ATATTCCAGT GCAGCCTTTA CCTATGTGGA GATCCCCTTC AGCATGGAAG 
CTACCACCCG CTAAAAGTGC TTTTAAAGCA CCCAAGCTCC CTCCAAAACC TCAGTTCCTT 
CACCGGAAGA CTATGGAAGT AAAGAACTCA CAGGCTTATT TGCGGTCAAA GCTTACAAAA 
GATACAACTT TGCCGGTCAC TTTAACGGAA TGGAAGCTTT TCCGAGCTGG TGAAGTTGCA 
AACACGAAAA GGAAAAATCT TCCAAGGCTT GTATTGAAAA TAGATGACAT ATTTGAATCT 
AAAAGAGGGA AGAAGAAGGT AAAGTTACAT TCTTACACTG GAAAGGAATT ACCTCCGACA 
AAAGGTGAAA CCAGTGGGAA CGAAAGTGAT GCCGAGTATC TGCCAAAGAA TCGCCATAAA 
CGCTTAGCAC AACTGCAACC GTCTTCCAAG AGGAATCCTC ACTACCAGAC CTTGGAGCGG 
GATCTTATTG AATTACAGGA GCAGCAGCTG TTTGAACTTT TTGTGGTGGT GTCTCTACAG 
AAGAAACCAT CAGGAATAAG CTATATTCCC CAGGTCATAC AACAATTCCC TGGCAAGGAT 
GATCATGGCT ATAAGCAGTC CAAAGACATG GAAGAGAGAC TTAAAGTTAT TCCAAAATTT 
TGTTTTCCTG ATTCAAAGGA CTGGATGCCA ACCTCAGAAC TCAAGAGTGA AACATTCTCC 
TTTGTCTTGA CTGGTGAAGA TGGAAGCCGG TGGTTTGGTT ACTGTAAGAA GCTCTTGCCA 
GTAGGCAAAG GAAAGCGACT CCCTGAGGTA TACTGCATGG TTAGTCGCCT AGGCTGCTTC 
AATCTTTTTT CAAAGATTCT GGATGAAGTA GAGAAGAGAA GAGAAATGTC TCCAGCCCTT 
GTTTACCCAT TCATGCGAAG TGTCATGGAA GCTCCTTTCC CAGCTCCTGG ACGCACCATC 
ACAGTTAAGA GTTACCTCCC TGGGGCTGGA GATGAGTCCA TTGAACTCTG CCGACCACTA 
GATTCCCGAT TGGAACATGT TGATTTTAAA TGTCTCTTTA AGTGCCTGAG TGTGTGTCAT 
CTCATCCGGG TCTGTGCCTC TCTCCTTTTG GAGCGTAGGG TAATCTTTGT TGCCAACAGC 
CTAAGCACCC TGTCAAAATG TGGCCATGCT GTGGTAGCTA CACTGTATCC GTTCACCTGG 
CAGCATACCT ATATCCCAGT CCTGCCAGCA TCTATGATTG ACATCGTGTG CTCACCTACA 
CCATTCCTTA TTGGAATCCT GTCTTGCTCC TTACCACAGC TCCAGGACCT ACCCATTGAA 
GAGGTGCTGA TAGTTGATCT CTGTGCAGAC AAGTTCTTAC AGGAGGTATC TGATGAGGAT 
GAAATTCTAC CACCAAAACT TCAAGCTGCC CTGATGCAGA TTTTGGAAGA ACGAAATGAA 
ATCTTGACTC AGGAGCAGAA TTTTTCACAA GATGTGACAC TCAACTCTCT GGTGTCCGAA 
GCATTTGTCA GGTTTTTTGT GGAGTTGGTA GGACATTATT CTTTGAACAT GACTGTCACT 
GAGCGTGGGG AGCGTGTTTT CCAAAGGGAA CCATTCCGTA AGTCCCACAC CTCCCGAAGT 
GTACGCCACT TCCTGGATCT CTTCATGGAA ACTCAGATGT TTGCAGGATT CATCCAGGAC 
CGAGAGCTTC GGAAAAGTGG AGTTAAAGGT TTGTTTGAGA TCCGGGCCAT CCAGTATTTG 
GAAACAATTC CTGAGTCGGA GCCCAGTGGG ATGAATAGAA TTTTGCGGAG TCTTGGAAGC 
AAAATGAAAT TTCTGCAAAA GAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243333.1
CDS	641..3427
Translation	MDVGFSRTTVQTLSRSHCKNIKQKISQWEGRANGISNPEKWCPKDFGVRYNCHQEIRLKKNPIAERKSKNLDVTSRENVGLDINENTKSHDQSENENKKHEYDDTHFFKNESESNWVCSRVKEIESCKEDVLDPETSLPPGNFYTSQILWKKIEALPPDKLLNLALEHCDSSEKELNFRVLDSSYGITKSLENIYSEPEGQECGPSINPLPKPRRTFRYLSESGVTPYKERNCDKKYCENNSCAQSSLASSQEPEPKKYGGKIRGRSKRKSFEFEDIQHFRNRNSQTIREELGRNSGSALYYTQSEDNIYEDIIYPTKENPYEDIPVQPLPMWRSPSAWKLPPAKSAFKAPKLPPKPQFLHRKTMEVKNSQAYLRSKLTKDTTLPVTLTEWKLFRAGEVANTKRKNLPRLVLKIDDIFESKRGKKKVKLHSYTGKELPPTKGETSGNESDAEYLPKNRHKRLAQLQPSSKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKPSGISYIPQVIQQFPGKDDHGYKQSKDMEERLKVIPKFCFPDSKDWMPTSELKSETFSFVLTGEDGSRWFGYCKKLLPVGKGKRLPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDESIELCRPLDSRLEHVDFKCLFKCLSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPASMIDIVCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEVSDEDEILPPKLQAALMQILEERNEILTQEQNFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFIQDRELRKSGVKGLFEIRAIQYLETIPESEPSGMNRILRSLGSKMKFLQKK

Target ORF information:

RefSeq Version	NM_001256404.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DENN domain containing 2C (DENND2C), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256404.2

ORF Insert Sequence:

ATGGATGTTG GTTTTTCTCG TACTACTGTT CAGACACTGT CAAGAAGCCA CTGCAAAAAC 
ATCAAACAAA AAATTTCTCA ATGGGAAGGA AGGGCTAATG GTATATCTAA TCCAGAAAAG 
TGGTGTCCAA AGGACTTTGG AGTGAGATAT AACTGTCACC AAGAGATCCG TCTTAAGAAA 
AATCCTATAG CTGAGAGAAA GAGCAAAAAC TTGGATGTAA CCAGCCGTGA AAATGTGGGT 
CTAGATATAA ATGAAAATAC CAAAAGCCAT GATCAAAGTG AGAATGAAAA TAAGAAACAT 
GAATATGACG ATACACACTT CTTTAAAAAT GAATCAGAAT CCAACTGGGT ATGTTCTCGG 
GTCAAAGAAA TTGAAAGCTG TAAAGAAGAT GTCTTAGATC CAGAGACTTC ATTACCTCCA 
GGAAACTTCT ATACCTCACA AATACTGTGG AAGAAAATAG AAGCACTTCC CCCAGATAAA 
CTCTTAAATT TGGCTTTAGA ACATTGTGAC TCTTCAGAAA AAGAACTGAA CTTCAGAGTT 
CTGGATAGTT CATACGGAAT AACCAAGAGC TTAGAAAATA TTTACTCTGA ACCTGAGGGG 
CAAGAATGTG GACCTTCCAT AAATCCTTTG CCAAAACCTC GTAGGACATT CAGATATTTA 
TCCGAATCTG GTGTTACGCC GTATAAAGAA AGAAACTGTG ACAAAAAATA CTGTGAAAAT 
AACTCTTGTG CACAATCTTC TTTGGCCTCT TCTCAGGAAC CTGAACCAAA GAAATATGGT 
GGAAAAATCA GAGGAAGATC TAAAAGGAAA TCCTTTGAAT TTGAGGATAT TCAGCACTTT 
CGAAATCGGA ACTCACAGAC GATTCGTGAA GAACTTGGAA GAAATTCTGG GTCAGCACTT 
TATTACACAC AGTCTGAGGA CAATATCTAT GAAGATATCA TATATCCCAC CAAAGAAAAT 
CCATATGAAG ATATTCCAGT GCAGCCTTTA CCTATGTGGA GATCCCCTTC AGCATGGAAG 
CTACCACCCG CTAAAAGTGC TTTTAAAGCA CCCAAGCTCC CTCCAAAACC TCAGTTCCTT 
CACCGGAAGA CTATGGAAGT AAAGAACTCA CAGGCTTATT TGCGGTCAAA GCTTACAAAA 
GATACAACTT TGCCGGTCAC TTTAACGGAA TGGAAGCTTT TCCGAGCTGG TGAAGTTGCA 
AACACGAAAA GGAAAAATCT TCCAAGGCTT GTATTGAAAA TAGATGACAT ATTTGAATCT 
AAAAGAGGGA AGAAGAAGGT AAAGTTACAT TCTTACACTG GAAAGGAATT ACCTCCGACA 
AAAGGTGAAA CCAGTGGGAA CGAAAGTGAT GCCGAGTATC TGCCAAAGAA TCGCCATAAA 
CGCTTAGCAC AACTGCAACC GTCTTCCAAG AGGAATCCTC ACTACCAGAC CTTGGAGCGG 
GATCTTATTG AATTACAGGA GCAGCAGCTG TTTGAACTTT TTGTGGTGGT GTCTCTACAG 
AAGAAACCAT CAGGAATAAG CTATATTCCC CAGGTCATAC AACAATTCCC TGGCAAGGAT 
GATCATGGCT ATAAGCAGTC CAAAGACATG GAAGAGAGAC TTAAAGTTAT TCCAAAATTT 
TGTTTTCCTG ATTCAAAGGA CTGGATGCCA ACCTCAGAAC TCAAGAGTGA AACATTCTCC 
TTTGTCTTGA CTGGTGAAGA TGGAAGCCGG TGGTTTGGTT ACTGTAAGAA GCTCTTGCCA 
GTAGGCAAAG GAAAGCGACT CCCTGAGGTA TACTGCATGG TTAGTCGCCT AGGCTGCTTC 
AATCTTTTTT CAAAGATTCT GGATGAAGTA GAGAAGAGAA GAGAAATGTC TCCAGCCCTT 
GTTTACCCAT TCATGCGAAG TGTCATGGAA GCTCCTTTCC CAGCTCCTGG ACGCACCATC 
ACAGTTAAGA GTTACCTCCC TGGGGCTGGA GATGAGTCCA TTGAACTCTG CCGACCACTA 
GATTCCCGAT TGGAACATGT TGATTTTAAA TGTCTCTTTA AGTGCCTGAG TGTGTGTCAT 
CTCATCCGGG TCTGTGCCTC TCTCCTTTTG GAGCGTAGGG TAATCTTTGT TGCCAACAGC 
CTAAGCACCC TGTCAAAATG TGGCCATGCT GTGGTAGCTA CACTGTATCC GTTCACCTGG 
CAGCATACCT ATATCCCAGT CCTGCCAGCA TCTATGATTG ACATCGTGTG CTCACCTACA 
CCATTCCTTA TTGGAATCCT GTCTTGCTCC TTACCACAGC TCCAGGACCT ACCCATTGAA 
GAGGTGCTGA TAGTTGATCT CTGTGCAGAC AAGTTCTTAC AGGAGGTATC TGATGAGGAT 
GAAATTCTAC CACCAAAACT TCAAGCTGCC CTGATGCAGA TTTTGGAAGA ACGAAATGAA 
ATCTTGACTC AGGAGCAGAA TTTTTCACAA GATGTGACAC TCAACTCTCT GGTGTCCGAA 
GCATTTGTCA GGTTTTTTGT GGAGTTGGTA GGACATTATT CTTTGAACAT GACTGTCACT 
GAGCGTGGGG AGCGTGTTTT CCAAAGGGAA CCATTCCGTA AGTCCCACAC CTCCCGAAGT 
GTACGCCACT TCCTGGATCT CTTCATGGAA ACTCAGATGT TTGCAGGATT CATCCAGGAC 
CGAGAGCTTC GGAAAAGTGG AGTTAAAGGT TTGTTTGAGA TCCGGGCCAT CCAGTATTTG 
GAAACAATTC CTGAGTCGGA GCCCAGTGGG ATGAATAGAA TTTTGCGGAG TCTTGGAAGC 
AAAATGAAAT TTCTGCAAAA GAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DENND2C ( NM_001256404.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243333.1 Homo sapiens DENN domain containing 2C (DENND2C), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15406
Clone ID Related Accession (Same CDS sequence)	NM_001256404.2 , NM_001256404.1
Accession Version	NM_001256404.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2787bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	DENN domain-containing protein 2C isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX647950.1, AL096773.6 and AL133382.8. Transcript Variant: This variant (1) represents the longer variant and it encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## CDS exon combination :: CR749576.1, SRR1803611.20527.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGATGTTG GTTTTTCTCG TACTACTGTT CAGACACTGT CAAGAAGCCA CTGCAAAAAC 
ATCAAACAAA AAATTTCTCA ATGGGAAGGA AGGGCTAATG GTATATCTAA TCCAGAAAAG 
TGGTGTCCAA AGGACTTTGG AGTGAGATAT AACTGTCACC AAGAGATCCG TCTTAAGAAA 
AATCCTATAG CTGAGAGAAA GAGCAAAAAC TTGGATGTAA CCAGCCGTGA AAATGTGGGT 
CTAGATATAA ATGAAAATAC CAAAAGCCAT GATCAAAGTG AGAATGAAAA TAAGAAACAT 
GAATATGACG ATACACACTT CTTTAAAAAT GAATCAGAAT CCAACTGGGT ATGTTCTCGG 
GTCAAAGAAA TTGAAAGCTG TAAAGAAGAT GTCTTAGATC CAGAGACTTC ATTACCTCCA 
GGAAACTTCT ATACCTCACA AATACTGTGG AAGAAAATAG AAGCACTTCC CCCAGATAAA 
CTCTTAAATT TGGCTTTAGA ACATTGTGAC TCTTCAGAAA AAGAACTGAA CTTCAGAGTT 
CTGGATAGTT CATACGGAAT AACCAAGAGC TTAGAAAATA TTTACTCTGA ACCTGAGGGG 
CAAGAATGTG GACCTTCCAT AAATCCTTTG CCAAAACCTC GTAGGACATT CAGATATTTA 
TCCGAATCTG GTGTTACGCC GTATAAAGAA AGAAACTGTG ACAAAAAATA CTGTGAAAAT 
AACTCTTGTG CACAATCTTC TTTGGCCTCT TCTCAGGAAC CTGAACCAAA GAAATATGGT 
GGAAAAATCA GAGGAAGATC TAAAAGGAAA TCCTTTGAAT TTGAGGATAT TCAGCACTTT 
CGAAATCGGA ACTCACAGAC GATTCGTGAA GAACTTGGAA GAAATTCTGG GTCAGCACTT 
TATTACACAC AGTCTGAGGA CAATATCTAT GAAGATATCA TATATCCCAC CAAAGAAAAT 
CCATATGAAG ATATTCCAGT GCAGCCTTTA CCTATGTGGA GATCCCCTTC AGCATGGAAG 
CTACCACCCG CTAAAAGTGC TTTTAAAGCA CCCAAGCTCC CTCCAAAACC TCAGTTCCTT 
CACCGGAAGA CTATGGAAGT AAAGAACTCA CAGGCTTATT TGCGGTCAAA GCTTACAAAA 
GATACAACTT TGCCGGTCAC TTTAACGGAA TGGAAGCTTT TCCGAGCTGG TGAAGTTGCA 
AACACGAAAA GGAAAAATCT TCCAAGGCTT GTATTGAAAA TAGATGACAT ATTTGAATCT 
AAAAGAGGGA AGAAGAAGGT AAAGTTACAT TCTTACACTG GAAAGGAATT ACCTCCGACA 
AAAGGTGAAA CCAGTGGGAA CGAAAGTGAT GCCGAGTATC TGCCAAAGAA TCGCCATAAA 
CGCTTAGCAC AACTGCAACC GTCTTCCAAG AGGAATCCTC ACTACCAGAC CTTGGAGCGG 
GATCTTATTG AATTACAGGA GCAGCAGCTG TTTGAACTTT TTGTGGTGGT GTCTCTACAG 
AAGAAACCAT CAGGAATAAG CTATATTCCC CAGGTCATAC AACAATTCCC TGGCAAGGAT 
GATCATGGCT ATAAGCAGTC CAAAGACATG GAAGAGAGAC TTAAAGTTAT TCCAAAATTT 
TGTTTTCCTG ATTCAAAGGA CTGGATGCCA ACCTCAGAAC TCAAGAGTGA AACATTCTCC 
TTTGTCTTGA CTGGTGAAGA TGGAAGCCGG TGGTTTGGTT ACTGTAAGAA GCTCTTGCCA 
GTAGGCAAAG GAAAGCGACT CCCTGAGGTA TACTGCATGG TTAGTCGCCT AGGCTGCTTC 
AATCTTTTTT CAAAGATTCT GGATGAAGTA GAGAAGAGAA GAGAAATGTC TCCAGCCCTT 
GTTTACCCAT TCATGCGAAG TGTCATGGAA GCTCCTTTCC CAGCTCCTGG ACGCACCATC 
ACAGTTAAGA GTTACCTCCC TGGGGCTGGA GATGAGTCCA TTGAACTCTG CCGACCACTA 
GATTCCCGAT TGGAACATGT TGATTTTAAA TGTCTCTTTA AGTGCCTGAG TGTGTGTCAT 
CTCATCCGGG TCTGTGCCTC TCTCCTTTTG GAGCGTAGGG TAATCTTTGT TGCCAACAGC 
CTAAGCACCC TGTCAAAATG TGGCCATGCT GTGGTAGCTA CACTGTATCC GTTCACCTGG 
CAGCATACCT ATATCCCAGT CCTGCCAGCA TCTATGATTG ACATCGTGTG CTCACCTACA 
CCATTCCTTA TTGGAATCCT GTCTTGCTCC TTACCACAGC TCCAGGACCT ACCCATTGAA 
GAGGTGCTGA TAGTTGATCT CTGTGCAGAC AAGTTCTTAC AGGAGGTATC TGATGAGGAT 
GAAATTCTAC CACCAAAACT TCAAGCTGCC CTGATGCAGA TTTTGGAAGA ACGAAATGAA 
ATCTTGACTC AGGAGCAGAA TTTTTCACAA GATGTGACAC TCAACTCTCT GGTGTCCGAA 
GCATTTGTCA GGTTTTTTGT GGAGTTGGTA GGACATTATT CTTTGAACAT GACTGTCACT 
GAGCGTGGGG AGCGTGTTTT CCAAAGGGAA CCATTCCGTA AGTCCCACAC CTCCCGAAGT 
GTACGCCACT TCCTGGATCT CTTCATGGAA ACTCAGATGT TTGCAGGATT CATCCAGGAC 
CGAGAGCTTC GGAAAAGTGG AGTTAAAGGT TTGTTTGAGA TCCGGGCCAT CCAGTATTTG 
GAAACAATTC CTGAGTCGGA GCCCAGTGGG ATGAATAGAA TTTTGCGGAG TCTTGGAAGC 
AAAATGAAAT TTCTGCAAAA GAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243333.1
CDS	703..3489
Translation	MDVGFSRTTVQTLSRSHCKNIKQKISQWEGRANGISNPEKWCPKDFGVRYNCHQEIRLKKNPIAERKSKNLDVTSRENVGLDINENTKSHDQSENENKKHEYDDTHFFKNESESNWVCSRVKEIESCKEDVLDPETSLPPGNFYTSQILWKKIEALPPDKLLNLALEHCDSSEKELNFRVLDSSYGITKSLENIYSEPEGQECGPSINPLPKPRRTFRYLSESGVTPYKERNCDKKYCENNSCAQSSLASSQEPEPKKYGGKIRGRSKRKSFEFEDIQHFRNRNSQTIREELGRNSGSALYYTQSEDNIYEDIIYPTKENPYEDIPVQPLPMWRSPSAWKLPPAKSAFKAPKLPPKPQFLHRKTMEVKNSQAYLRSKLTKDTTLPVTLTEWKLFRAGEVANTKRKNLPRLVLKIDDIFESKRGKKKVKLHSYTGKELPPTKGETSGNESDAEYLPKNRHKRLAQLQPSSKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKPSGISYIPQVIQQFPGKDDHGYKQSKDMEERLKVIPKFCFPDSKDWMPTSELKSETFSFVLTGEDGSRWFGYCKKLLPVGKGKRLPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDESIELCRPLDSRLEHVDFKCLFKCLSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPASMIDIVCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEVSDEDEILPPKLQAALMQILEERNEILTQEQNFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFIQDRELRKSGVKGLFEIRAIQYLETIPESEPSGMNRILRSLGSKMKFLQKK

Target ORF information:

RefSeq Version	NM_001256404.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DENN domain containing 2C (DENND2C), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256404.1

ORF Insert Sequence:

ATGGATGTTG GTTTTTCTCG TACTACTGTT CAGACACTGT CAAGAAGCCA CTGCAAAAAC 
ATCAAACAAA AAATTTCTCA ATGGGAAGGA AGGGCTAATG GTATATCTAA TCCAGAAAAG 
TGGTGTCCAA AGGACTTTGG AGTGAGATAT AACTGTCACC AAGAGATCCG TCTTAAGAAA 
AATCCTATAG CTGAGAGAAA GAGCAAAAAC TTGGATGTAA CCAGCCGTGA AAATGTGGGT 
CTAGATATAA ATGAAAATAC CAAAAGCCAT GATCAAAGTG AGAATGAAAA TAAGAAACAT 
GAATATGACG ATACACACTT CTTTAAAAAT GAATCAGAAT CCAACTGGGT ATGTTCTCGG 
GTCAAAGAAA TTGAAAGCTG TAAAGAAGAT GTCTTAGATC CAGAGACTTC ATTACCTCCA 
GGAAACTTCT ATACCTCACA AATACTGTGG AAGAAAATAG AAGCACTTCC CCCAGATAAA 
CTCTTAAATT TGGCTTTAGA ACATTGTGAC TCTTCAGAAA AAGAACTGAA CTTCAGAGTT 
CTGGATAGTT CATACGGAAT AACCAAGAGC TTAGAAAATA TTTACTCTGA ACCTGAGGGG 
CAAGAATGTG GACCTTCCAT AAATCCTTTG CCAAAACCTC GTAGGACATT CAGATATTTA 
TCCGAATCTG GTGTTACGCC GTATAAAGAA AGAAACTGTG ACAAAAAATA CTGTGAAAAT 
AACTCTTGTG CACAATCTTC TTTGGCCTCT TCTCAGGAAC CTGAACCAAA GAAATATGGT 
GGAAAAATCA GAGGAAGATC TAAAAGGAAA TCCTTTGAAT TTGAGGATAT TCAGCACTTT 
CGAAATCGGA ACTCACAGAC GATTCGTGAA GAACTTGGAA GAAATTCTGG GTCAGCACTT 
TATTACACAC AGTCTGAGGA CAATATCTAT GAAGATATCA TATATCCCAC CAAAGAAAAT 
CCATATGAAG ATATTCCAGT GCAGCCTTTA CCTATGTGGA GATCCCCTTC AGCATGGAAG 
CTACCACCCG CTAAAAGTGC TTTTAAAGCA CCCAAGCTCC CTCCAAAACC TCAGTTCCTT 
CACCGGAAGA CTATGGAAGT AAAGAACTCA CAGGCTTATT TGCGGTCAAA GCTTACAAAA 
GATACAACTT TGCCGGTCAC TTTAACGGAA TGGAAGCTTT TCCGAGCTGG TGAAGTTGCA 
AACACGAAAA GGAAAAATCT TCCAAGGCTT GTATTGAAAA TAGATGACAT ATTTGAATCT 
AAAAGAGGGA AGAAGAAGGT AAAGTTACAT TCTTACACTG GAAAGGAATT ACCTCCGACA 
AAAGGTGAAA CCAGTGGGAA CGAAAGTGAT GCCGAGTATC TGCCAAAGAA TCGCCATAAA 
CGCTTAGCAC AACTGCAACC GTCTTCCAAG AGGAATCCTC ACTACCAGAC CTTGGAGCGG 
GATCTTATTG AATTACAGGA GCAGCAGCTG TTTGAACTTT TTGTGGTGGT GTCTCTACAG 
AAGAAACCAT CAGGAATAAG CTATATTCCC CAGGTCATAC AACAATTCCC TGGCAAGGAT 
GATCATGGCT ATAAGCAGTC CAAAGACATG GAAGAGAGAC TTAAAGTTAT TCCAAAATTT 
TGTTTTCCTG ATTCAAAGGA CTGGATGCCA ACCTCAGAAC TCAAGAGTGA AACATTCTCC 
TTTGTCTTGA CTGGTGAAGA TGGAAGCCGG TGGTTTGGTT ACTGTAAGAA GCTCTTGCCA 
GTAGGCAAAG GAAAGCGACT CCCTGAGGTA TACTGCATGG TTAGTCGCCT AGGCTGCTTC 
AATCTTTTTT CAAAGATTCT GGATGAAGTA GAGAAGAGAA GAGAAATGTC TCCAGCCCTT 
GTTTACCCAT TCATGCGAAG TGTCATGGAA GCTCCTTTCC CAGCTCCTGG ACGCACCATC 
ACAGTTAAGA GTTACCTCCC TGGGGCTGGA GATGAGTCCA TTGAACTCTG CCGACCACTA 
GATTCCCGAT TGGAACATGT TGATTTTAAA TGTCTCTTTA AGTGCCTGAG TGTGTGTCAT 
CTCATCCGGG TCTGTGCCTC TCTCCTTTTG GAGCGTAGGG TAATCTTTGT TGCCAACAGC 
CTAAGCACCC TGTCAAAATG TGGCCATGCT GTGGTAGCTA CACTGTATCC GTTCACCTGG 
CAGCATACCT ATATCCCAGT CCTGCCAGCA TCTATGATTG ACATCGTGTG CTCACCTACA 
CCATTCCTTA TTGGAATCCT GTCTTGCTCC TTACCACAGC TCCAGGACCT ACCCATTGAA 
GAGGTGCTGA TAGTTGATCT CTGTGCAGAC AAGTTCTTAC AGGAGGTATC TGATGAGGAT 
GAAATTCTAC CACCAAAACT TCAAGCTGCC CTGATGCAGA TTTTGGAAGA ACGAAATGAA 
ATCTTGACTC AGGAGCAGAA TTTTTCACAA GATGTGACAC TCAACTCTCT GGTGTCCGAA 
GCATTTGTCA GGTTTTTTGT GGAGTTGGTA GGACATTATT CTTTGAACAT GACTGTCACT 
GAGCGTGGGG AGCGTGTTTT CCAAAGGGAA CCATTCCGTA AGTCCCACAC CTCCCGAAGT 
GTACGCCACT TCCTGGATCT CTTCATGGAA ACTCAGATGT TTGCAGGATT CATCCAGGAC 
CGAGAGCTTC GGAAAAGTGG AGTTAAAGGT TTGTTTGAGA TCCGGGCCAT CCAGTATTTG 
GAAACAATTC CTGAGTCGGA GCCCAGTGGG ATGAATAGAA TTTTGCGGAG TCTTGGAAGC 
AAAATGAAAT TTCTGCAAAA GAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DENND2C ( NM_198459.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_940861.3 Homo sapiens DENN domain containing 2C (DENND2C), transcript variant 2, mRNA.

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CloneID	OHu15410
Clone ID Related Accession (Same CDS sequence)	NM_198459.4 , NM_198459.3
Accession Version	NM_198459.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2616bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-30
Organism	Homo sapiens(human)
Product	DENN domain-containing protein 2C isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX647950.1, DB071246.1, BC063894.1, AL133382.8 and AL390241.19. On May 31, 2019 this sequence version replaced NM_198459.3. Transcript Variant: This variant (2) lacks several exons in the 5' UTR and in the coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGATGTTG GTTTTTCTCG TACTACTGTT CAGACACTGT CAAGAAGCCA CTGCAAAAAC 
ATCAAACAAA AAATTTCTCA ATGGGAAGGA AGGGCTAATG GTATATCTAA TCCAGAAAAG 
TGGTGTCCAA AGGACTTTGG AGTGAGATAT AACTGTCACC AAGAGATCCG TCTTAAGAAA 
AATCCTATAG CTGAGAGAAA GAGCAAAAAC TTGGATGTAA CCAGCCGTGA AAATGTGGGT 
CTAGATATAA ATGAAAATAC CAAAAGCCAT GATCAAAGTG AGAATGAAAA TAAGAAACAT 
GAATATGACG ATACACACTT CTTTAAAAAT GAATCAGAAT CCAACTGGGT ATGTTCTCGG 
GTCAAAGAAA TTGAAAGCTG TAAAGAAGAT GTCTTAGATC CAGAGACTTC ATTACCTCCA 
GGAAACTTCT ATACCTCACA AATACTGTGG AAGAAAATAG AAGCACTTCC CCCAGATAAA 
CTCTTAAATT TGGCTTTAGA ACATTGTGAC TCTTCAGAAA AAGAACTGAA CTTCAGAGTT 
CTGGATAGTT CATACGGAAT AACCAAGAGC TTAGAAAATA TTTACTCTGA ACCTGAGGGG 
CAAGAATGTG GACCTTCCAT AAATCCTTTG CCAAAACCTC GTAGGACATT CAGATATTTA 
TCCGAATCTG GTGTTACGCC GTATAAAGAA AGAAACTGTG ACAAAAAATA CTGTGAAAAT 
AACTCTTGTG CACAATCTTC TTTGGCCTCT TCTCAGGAAC CTGAACCAAA GAAATATGGT 
GGAAAAATCA GAGGAAGATC TAAAAGGAAA TCCTTTGAAT TTGAGGATAT TCAGCACTTT 
CGAAATCGGA ACTCACAGAC GATTCGTGAA GAACTTGGAA GAAATTCTGG GTCAGCACTT 
TATTACACAC AGTCTGAGGA CAATATCTAT GAAGATATCA TATATCCCAC CAAAGAAAAT 
CCATATGAAG ATATTCCAGT GCAGCCTTTA CCTATGTGGA GATCCCCTTC AGCATGGAAG 
CTACCACCCG CTAAAAGTGC TTTTAAAGCA CCCAAGCTTG TATTGAAAAT AGATGACATA 
TTTGAATCTA AAAGAGGGAA GAAGAAGGTA AAGTTACATT CTTACACTGG AAAGGAATTA 
CCTCCGACAA AAGGTGAAAC CAGTGGGAAC GAAAGTGATG CCGAGTATCT GCCAAAGAAT 
CGCCATAAAC GCTTAGCACA ACTGCAACCG TCTTCCAAGA GGAATCCTCA CTACCAGACC 
TTGGAGCGGG ATCTTATTGA ATTACAGGAG CAGCAGCTGT TTGAACTTTT TGTGGTGGTG 
TCTCTACAGA AGAAACCATC AGGAATAAGC TATATTCCCC AGGTCATACA ACAATTCCCT 
GGCAAGGATG ATCATGGCTA TAAGCAGTCC AAAGACATGG AAGAGAGACT TAAAGTTATT 
CCAAAATTTT GTTTTCCTGA TTCAAAGGAC TGGATGCCAA CCTCAGAACT CAAGAGTGAA 
ACATTCTCCT TTGTCTTGAC TGGTGAAGAT GGAAGCCGGT GGTTTGGTTA CTGTAAGAAG 
CTCTTGCCAG TAGGCAAAGG AAAGCGACTC CCTGAGGTAT ACTGCATGGT TAGTCGCCTA 
GGCTGCTTCA ATCTTTTTTC AAAGATTCTG GATGAAGTAG AGAAGAGAAG AGAAATGTCT 
CCAGCCCTTG TTTACCCATT CATGCGAAGT GTCATGGAAG CTCCTTTCCC AGCTCCTGGA 
CGCACCATCA CAGTTAAGAG TTACCTCCCT GGGGCTGGAG ATGAGTCCAT TGAACTCTGC 
CGACCACTAG ATTCCCGATT GGAACATGTT GATTTTAAAT GTCTCTTTAA GTGCCTGAGT 
GTGTGTCATC TCATCCGGGT CTGTGCCTCT CTCCTTTTGG AGCGTAGGGT AATCTTTGTT 
GCCAACAGCC TAAGCACCCT GTCAAAATGT GGCCATGCTG TGGTAGCTAC ACTGTATCCG 
TTCACCTGGC AGCATACCTA TATCCCAGTC CTGCCAGCAT CTATGATTGA CATCGTGTGC 
TCACCTACAC CATTCCTTAT TGGAATCCTG TCTTGCTCCT TACCACAGCT CCAGGACCTA 
CCCATTGAAG AGGTGCTGAT AGTTGATCTC TGTGCAGACA AGTTCTTACA GGAGGTATCT 
GATGAGGATG AAATTCTACC ACCAAAACTT CAAGCTGCCC TGATGCAGAT TTTGGAAGAA 
CGAAATGAAA TCTTGACTCA GGAGCAGAAT TTTTCACAAG ATGTGACACT CAACTCTCTG 
GTGTCCGAAG CATTTGTCAG GTTTTTTGTG GAGTTGGTAG GACATTATTC TTTGAACATG 
ACTGTCACTG AGCGTGGGGA GCGTGTTTTC CAAAGGGAAC CATTCCGTAA GTCCCACACC 
TCCCGAAGTG TACGCCACTT CCTGGATCTC TTCATGGAAA CTCAGATGTT TGCAGGATTC 
ATCCAGGACC GAGAGCTTCG GAAAAGTGGA GTTAAAGGTT TGTTTGAGAT CCGGGCCATC 
CAGTATTTGG AAACAATTCC TGAGTCGGAG CCCAGTGGGA TGAATAGAAT TTTGCGGAGT 
CTTGGAAGCA AAATGAAATT TCTGCAAAAG AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_940861.3
CDS	272..2887
Translation	MDVGFSRTTVQTLSRSHCKNIKQKISQWEGRANGISNPEKWCPKDFGVRYNCHQEIRLKKNPIAERKSKNLDVTSRENVGLDINENTKSHDQSENENKKHEYDDTHFFKNESESNWVCSRVKEIESCKEDVLDPETSLPPGNFYTSQILWKKIEALPPDKLLNLALEHCDSSEKELNFRVLDSSYGITKSLENIYSEPEGQECGPSINPLPKPRRTFRYLSESGVTPYKERNCDKKYCENNSCAQSSLASSQEPEPKKYGGKIRGRSKRKSFEFEDIQHFRNRNSQTIREELGRNSGSALYYTQSEDNIYEDIIYPTKENPYEDIPVQPLPMWRSPSAWKLPPAKSAFKAPKLVLKIDDIFESKRGKKKVKLHSYTGKELPPTKGETSGNESDAEYLPKNRHKRLAQLQPSSKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKPSGISYIPQVIQQFPGKDDHGYKQSKDMEERLKVIPKFCFPDSKDWMPTSELKSETFSFVLTGEDGSRWFGYCKKLLPVGKGKRLPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDESIELCRPLDSRLEHVDFKCLFKCLSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPASMIDIVCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEVSDEDEILPPKLQAALMQILEERNEILTQEQNFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFIQDRELRKSGVKGLFEIRAIQYLETIPESEPSGMNRILRSLGSKMKFLQKK

Target ORF information:

RefSeq Version	NM_198459.4
Organism	Homo sapiens(human)
Definition	Homo sapiens DENN domain containing 2C (DENND2C), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198459.4

ORF Insert Sequence:

ATGGATGTTG GTTTTTCTCG TACTACTGTT CAGACACTGT CAAGAAGCCA CTGCAAAAAC 
ATCAAACAAA AAATTTCTCA ATGGGAAGGA AGGGCTAATG GTATATCTAA TCCAGAAAAG 
TGGTGTCCAA AGGACTTTGG AGTGAGATAT AACTGTCACC AAGAGATCCG TCTTAAGAAA 
AATCCTATAG CTGAGAGAAA GAGCAAAAAC TTGGATGTAA CCAGCCGTGA AAATGTGGGT 
CTAGATATAA ATGAAAATAC CAAAAGCCAT GATCAAAGTG AGAATGAAAA TAAGAAACAT 
GAATATGACG ATACACACTT CTTTAAAAAT GAATCAGAAT CCAACTGGGT ATGTTCTCGG 
GTCAAAGAAA TTGAAAGCTG TAAAGAAGAT GTCTTAGATC CAGAGACTTC ATTACCTCCA 
GGAAACTTCT ATACCTCACA AATACTGTGG AAGAAAATAG AAGCACTTCC CCCAGATAAA 
CTCTTAAATT TGGCTTTAGA ACATTGTGAC TCTTCAGAAA AAGAACTGAA CTTCAGAGTT 
CTGGATAGTT CATACGGAAT AACCAAGAGC TTAGAAAATA TTTACTCTGA ACCTGAGGGG 
CAAGAATGTG GACCTTCCAT AAATCCTTTG CCAAAACCTC GTAGGACATT CAGATATTTA 
TCCGAATCTG GTGTTACGCC GTATAAAGAA AGAAACTGTG ACAAAAAATA CTGTGAAAAT 
AACTCTTGTG CACAATCTTC TTTGGCCTCT TCTCAGGAAC CTGAACCAAA GAAATATGGT 
GGAAAAATCA GAGGAAGATC TAAAAGGAAA TCCTTTGAAT TTGAGGATAT TCAGCACTTT 
CGAAATCGGA ACTCACAGAC GATTCGTGAA GAACTTGGAA GAAATTCTGG GTCAGCACTT 
TATTACACAC AGTCTGAGGA CAATATCTAT GAAGATATCA TATATCCCAC CAAAGAAAAT 
CCATATGAAG ATATTCCAGT GCAGCCTTTA CCTATGTGGA GATCCCCTTC AGCATGGAAG 
CTACCACCCG CTAAAAGTGC TTTTAAAGCA CCCAAGCTTG TATTGAAAAT AGATGACATA 
TTTGAATCTA AAAGAGGGAA GAAGAAGGTA AAGTTACATT CTTACACTGG AAAGGAATTA 
CCTCCGACAA AAGGTGAAAC CAGTGGGAAC GAAAGTGATG CCGAGTATCT GCCAAAGAAT 
CGCCATAAAC GCTTAGCACA ACTGCAACCG TCTTCCAAGA GGAATCCTCA CTACCAGACC 
TTGGAGCGGG ATCTTATTGA ATTACAGGAG CAGCAGCTGT TTGAACTTTT TGTGGTGGTG 
TCTCTACAGA AGAAACCATC AGGAATAAGC TATATTCCCC AGGTCATACA ACAATTCCCT 
GGCAAGGATG ATCATGGCTA TAAGCAGTCC AAAGACATGG AAGAGAGACT TAAAGTTATT 
CCAAAATTTT GTTTTCCTGA TTCAAAGGAC TGGATGCCAA CCTCAGAACT CAAGAGTGAA 
ACATTCTCCT TTGTCTTGAC TGGTGAAGAT GGAAGCCGGT GGTTTGGTTA CTGTAAGAAG 
CTCTTGCCAG TAGGCAAAGG AAAGCGACTC CCTGAGGTAT ACTGCATGGT TAGTCGCCTA 
GGCTGCTTCA ATCTTTTTTC AAAGATTCTG GATGAAGTAG AGAAGAGAAG AGAAATGTCT 
CCAGCCCTTG TTTACCCATT CATGCGAAGT GTCATGGAAG CTCCTTTCCC AGCTCCTGGA 
CGCACCATCA CAGTTAAGAG TTACCTCCCT GGGGCTGGAG ATGAGTCCAT TGAACTCTGC 
CGACCACTAG ATTCCCGATT GGAACATGTT GATTTTAAAT GTCTCTTTAA GTGCCTGAGT 
GTGTGTCATC TCATCCGGGT CTGTGCCTCT CTCCTTTTGG AGCGTAGGGT AATCTTTGTT 
GCCAACAGCC TAAGCACCCT GTCAAAATGT GGCCATGCTG TGGTAGCTAC ACTGTATCCG 
TTCACCTGGC AGCATACCTA TATCCCAGTC CTGCCAGCAT CTATGATTGA CATCGTGTGC 
TCACCTACAC CATTCCTTAT TGGAATCCTG TCTTGCTCCT TACCACAGCT CCAGGACCTA 
CCCATTGAAG AGGTGCTGAT AGTTGATCTC TGTGCAGACA AGTTCTTACA GGAGGTATCT 
GATGAGGATG AAATTCTACC ACCAAAACTT CAAGCTGCCC TGATGCAGAT TTTGGAAGAA 
CGAAATGAAA TCTTGACTCA GGAGCAGAAT TTTTCACAAG ATGTGACACT CAACTCTCTG 
GTGTCCGAAG CATTTGTCAG GTTTTTTGTG GAGTTGGTAG GACATTATTC TTTGAACATG 
ACTGTCACTG AGCGTGGGGA GCGTGTTTTC CAAAGGGAAC CATTCCGTAA GTCCCACACC 
TCCCGAAGTG TACGCCACTT CCTGGATCTC TTCATGGAAA CTCAGATGTT TGCAGGATTC 
ATCCAGGACC GAGAGCTTCG GAAAAGTGGA GTTAAAGGTT TGTTTGAGAT CCGGGCCATC 
CAGTATTTGG AAACAATTCC TGAGTCGGAG CCCAGTGGGA TGAATAGAAT TTTGCGGAGT 
CTTGGAAGCA AAATGAAATT TCTGCAAAAG AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DENND2C ( NM_198459.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_940861.3 Homo sapiens DENN domain containing 2C (DENND2C), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15410
Clone ID Related Accession (Same CDS sequence)	NM_198459.4 , NM_198459.3
Accession Version	NM_198459.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2616bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	DENN domain-containing protein 2C isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX647950.1, DB071246.1, BC063894.1 and AL133382.8. On Jan 12, 2007 this sequence version replaced NM_198459.2. Transcript Variant: This variant (2) lacks several exons in the 5' UTR and in the coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1. ##Evidence-Data-START## CDS exon combination :: BX647950.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGATGTTG GTTTTTCTCG TACTACTGTT CAGACACTGT CAAGAAGCCA CTGCAAAAAC 
ATCAAACAAA AAATTTCTCA ATGGGAAGGA AGGGCTAATG GTATATCTAA TCCAGAAAAG 
TGGTGTCCAA AGGACTTTGG AGTGAGATAT AACTGTCACC AAGAGATCCG TCTTAAGAAA 
AATCCTATAG CTGAGAGAAA GAGCAAAAAC TTGGATGTAA CCAGCCGTGA AAATGTGGGT 
CTAGATATAA ATGAAAATAC CAAAAGCCAT GATCAAAGTG AGAATGAAAA TAAGAAACAT 
GAATATGACG ATACACACTT CTTTAAAAAT GAATCAGAAT CCAACTGGGT ATGTTCTCGG 
GTCAAAGAAA TTGAAAGCTG TAAAGAAGAT GTCTTAGATC CAGAGACTTC ATTACCTCCA 
GGAAACTTCT ATACCTCACA AATACTGTGG AAGAAAATAG AAGCACTTCC CCCAGATAAA 
CTCTTAAATT TGGCTTTAGA ACATTGTGAC TCTTCAGAAA AAGAACTGAA CTTCAGAGTT 
CTGGATAGTT CATACGGAAT AACCAAGAGC TTAGAAAATA TTTACTCTGA ACCTGAGGGG 
CAAGAATGTG GACCTTCCAT AAATCCTTTG CCAAAACCTC GTAGGACATT CAGATATTTA 
TCCGAATCTG GTGTTACGCC GTATAAAGAA AGAAACTGTG ACAAAAAATA CTGTGAAAAT 
AACTCTTGTG CACAATCTTC TTTGGCCTCT TCTCAGGAAC CTGAACCAAA GAAATATGGT 
GGAAAAATCA GAGGAAGATC TAAAAGGAAA TCCTTTGAAT TTGAGGATAT TCAGCACTTT 
CGAAATCGGA ACTCACAGAC GATTCGTGAA GAACTTGGAA GAAATTCTGG GTCAGCACTT 
TATTACACAC AGTCTGAGGA CAATATCTAT GAAGATATCA TATATCCCAC CAAAGAAAAT 
CCATATGAAG ATATTCCAGT GCAGCCTTTA CCTATGTGGA GATCCCCTTC AGCATGGAAG 
CTACCACCCG CTAAAAGTGC TTTTAAAGCA CCCAAGCTTG TATTGAAAAT AGATGACATA 
TTTGAATCTA AAAGAGGGAA GAAGAAGGTA AAGTTACATT CTTACACTGG AAAGGAATTA 
CCTCCGACAA AAGGTGAAAC CAGTGGGAAC GAAAGTGATG CCGAGTATCT GCCAAAGAAT 
CGCCATAAAC GCTTAGCACA ACTGCAACCG TCTTCCAAGA GGAATCCTCA CTACCAGACC 
TTGGAGCGGG ATCTTATTGA ATTACAGGAG CAGCAGCTGT TTGAACTTTT TGTGGTGGTG 
TCTCTACAGA AGAAACCATC AGGAATAAGC TATATTCCCC AGGTCATACA ACAATTCCCT 
GGCAAGGATG ATCATGGCTA TAAGCAGTCC AAAGACATGG AAGAGAGACT TAAAGTTATT 
CCAAAATTTT GTTTTCCTGA TTCAAAGGAC TGGATGCCAA CCTCAGAACT CAAGAGTGAA 
ACATTCTCCT TTGTCTTGAC TGGTGAAGAT GGAAGCCGGT GGTTTGGTTA CTGTAAGAAG 
CTCTTGCCAG TAGGCAAAGG AAAGCGACTC CCTGAGGTAT ACTGCATGGT TAGTCGCCTA 
GGCTGCTTCA ATCTTTTTTC AAAGATTCTG GATGAAGTAG AGAAGAGAAG AGAAATGTCT 
CCAGCCCTTG TTTACCCATT CATGCGAAGT GTCATGGAAG CTCCTTTCCC AGCTCCTGGA 
CGCACCATCA CAGTTAAGAG TTACCTCCCT GGGGCTGGAG ATGAGTCCAT TGAACTCTGC 
CGACCACTAG ATTCCCGATT GGAACATGTT GATTTTAAAT GTCTCTTTAA GTGCCTGAGT 
GTGTGTCATC TCATCCGGGT CTGTGCCTCT CTCCTTTTGG AGCGTAGGGT AATCTTTGTT 
GCCAACAGCC TAAGCACCCT GTCAAAATGT GGCCATGCTG TGGTAGCTAC ACTGTATCCG 
TTCACCTGGC AGCATACCTA TATCCCAGTC CTGCCAGCAT CTATGATTGA CATCGTGTGC 
TCACCTACAC CATTCCTTAT TGGAATCCTG TCTTGCTCCT TACCACAGCT CCAGGACCTA 
CCCATTGAAG AGGTGCTGAT AGTTGATCTC TGTGCAGACA AGTTCTTACA GGAGGTATCT 
GATGAGGATG AAATTCTACC ACCAAAACTT CAAGCTGCCC TGATGCAGAT TTTGGAAGAA 
CGAAATGAAA TCTTGACTCA GGAGCAGAAT TTTTCACAAG ATGTGACACT CAACTCTCTG 
GTGTCCGAAG CATTTGTCAG GTTTTTTGTG GAGTTGGTAG GACATTATTC TTTGAACATG 
ACTGTCACTG AGCGTGGGGA GCGTGTTTTC CAAAGGGAAC CATTCCGTAA GTCCCACACC 
TCCCGAAGTG TACGCCACTT CCTGGATCTC TTCATGGAAA CTCAGATGTT TGCAGGATTC 
ATCCAGGACC GAGAGCTTCG GAAAAGTGGA GTTAAAGGTT TGTTTGAGAT CCGGGCCATC 
CAGTATTTGG AAACAATTCC TGAGTCGGAG CCCAGTGGGA TGAATAGAAT TTTGCGGAGT 
CTTGGAAGCA AAATGAAATT TCTGCAAAAG AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_940861.3
CDS	334..2949
Translation	MDVGFSRTTVQTLSRSHCKNIKQKISQWEGRANGISNPEKWCPKDFGVRYNCHQEIRLKKNPIAERKSKNLDVTSRENVGLDINENTKSHDQSENENKKHEYDDTHFFKNESESNWVCSRVKEIESCKEDVLDPETSLPPGNFYTSQILWKKIEALPPDKLLNLALEHCDSSEKELNFRVLDSSYGITKSLENIYSEPEGQECGPSINPLPKPRRTFRYLSESGVTPYKERNCDKKYCENNSCAQSSLASSQEPEPKKYGGKIRGRSKRKSFEFEDIQHFRNRNSQTIREELGRNSGSALYYTQSEDNIYEDIIYPTKENPYEDIPVQPLPMWRSPSAWKLPPAKSAFKAPKLVLKIDDIFESKRGKKKVKLHSYTGKELPPTKGETSGNESDAEYLPKNRHKRLAQLQPSSKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKPSGISYIPQVIQQFPGKDDHGYKQSKDMEERLKVIPKFCFPDSKDWMPTSELKSETFSFVLTGEDGSRWFGYCKKLLPVGKGKRLPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDESIELCRPLDSRLEHVDFKCLFKCLSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPASMIDIVCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEVSDEDEILPPKLQAALMQILEERNEILTQEQNFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFIQDRELRKSGVKGLFEIRAIQYLETIPESEPSGMNRILRSLGSKMKFLQKK

Target ORF information:

RefSeq Version	NM_198459.3
Organism	Homo sapiens(human)
Definition	Homo sapiens DENN domain containing 2C (DENND2C), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198459.3

ORF Insert Sequence:

ATGGATGTTG GTTTTTCTCG TACTACTGTT CAGACACTGT CAAGAAGCCA CTGCAAAAAC 
ATCAAACAAA AAATTTCTCA ATGGGAAGGA AGGGCTAATG GTATATCTAA TCCAGAAAAG 
TGGTGTCCAA AGGACTTTGG AGTGAGATAT AACTGTCACC AAGAGATCCG TCTTAAGAAA 
AATCCTATAG CTGAGAGAAA GAGCAAAAAC TTGGATGTAA CCAGCCGTGA AAATGTGGGT 
CTAGATATAA ATGAAAATAC CAAAAGCCAT GATCAAAGTG AGAATGAAAA TAAGAAACAT 
GAATATGACG ATACACACTT CTTTAAAAAT GAATCAGAAT CCAACTGGGT ATGTTCTCGG 
GTCAAAGAAA TTGAAAGCTG TAAAGAAGAT GTCTTAGATC CAGAGACTTC ATTACCTCCA 
GGAAACTTCT ATACCTCACA AATACTGTGG AAGAAAATAG AAGCACTTCC CCCAGATAAA 
CTCTTAAATT TGGCTTTAGA ACATTGTGAC TCTTCAGAAA AAGAACTGAA CTTCAGAGTT 
CTGGATAGTT CATACGGAAT AACCAAGAGC TTAGAAAATA TTTACTCTGA ACCTGAGGGG 
CAAGAATGTG GACCTTCCAT AAATCCTTTG CCAAAACCTC GTAGGACATT CAGATATTTA 
TCCGAATCTG GTGTTACGCC GTATAAAGAA AGAAACTGTG ACAAAAAATA CTGTGAAAAT 
AACTCTTGTG CACAATCTTC TTTGGCCTCT TCTCAGGAAC CTGAACCAAA GAAATATGGT 
GGAAAAATCA GAGGAAGATC TAAAAGGAAA TCCTTTGAAT TTGAGGATAT TCAGCACTTT 
CGAAATCGGA ACTCACAGAC GATTCGTGAA GAACTTGGAA GAAATTCTGG GTCAGCACTT 
TATTACACAC AGTCTGAGGA CAATATCTAT GAAGATATCA TATATCCCAC CAAAGAAAAT 
CCATATGAAG ATATTCCAGT GCAGCCTTTA CCTATGTGGA GATCCCCTTC AGCATGGAAG 
CTACCACCCG CTAAAAGTGC TTTTAAAGCA CCCAAGCTTG TATTGAAAAT AGATGACATA 
TTTGAATCTA AAAGAGGGAA GAAGAAGGTA AAGTTACATT CTTACACTGG AAAGGAATTA 
CCTCCGACAA AAGGTGAAAC CAGTGGGAAC GAAAGTGATG CCGAGTATCT GCCAAAGAAT 
CGCCATAAAC GCTTAGCACA ACTGCAACCG TCTTCCAAGA GGAATCCTCA CTACCAGACC 
TTGGAGCGGG ATCTTATTGA ATTACAGGAG CAGCAGCTGT TTGAACTTTT TGTGGTGGTG 
TCTCTACAGA AGAAACCATC AGGAATAAGC TATATTCCCC AGGTCATACA ACAATTCCCT 
GGCAAGGATG ATCATGGCTA TAAGCAGTCC AAAGACATGG AAGAGAGACT TAAAGTTATT 
CCAAAATTTT GTTTTCCTGA TTCAAAGGAC TGGATGCCAA CCTCAGAACT CAAGAGTGAA 
ACATTCTCCT TTGTCTTGAC TGGTGAAGAT GGAAGCCGGT GGTTTGGTTA CTGTAAGAAG 
CTCTTGCCAG TAGGCAAAGG AAAGCGACTC CCTGAGGTAT ACTGCATGGT TAGTCGCCTA 
GGCTGCTTCA ATCTTTTTTC AAAGATTCTG GATGAAGTAG AGAAGAGAAG AGAAATGTCT 
CCAGCCCTTG TTTACCCATT CATGCGAAGT GTCATGGAAG CTCCTTTCCC AGCTCCTGGA 
CGCACCATCA CAGTTAAGAG TTACCTCCCT GGGGCTGGAG ATGAGTCCAT TGAACTCTGC 
CGACCACTAG ATTCCCGATT GGAACATGTT GATTTTAAAT GTCTCTTTAA GTGCCTGAGT 
GTGTGTCATC TCATCCGGGT CTGTGCCTCT CTCCTTTTGG AGCGTAGGGT AATCTTTGTT 
GCCAACAGCC TAAGCACCCT GTCAAAATGT GGCCATGCTG TGGTAGCTAC ACTGTATCCG 
TTCACCTGGC AGCATACCTA TATCCCAGTC CTGCCAGCAT CTATGATTGA CATCGTGTGC 
TCACCTACAC CATTCCTTAT TGGAATCCTG TCTTGCTCCT TACCACAGCT CCAGGACCTA 
CCCATTGAAG AGGTGCTGAT AGTTGATCTC TGTGCAGACA AGTTCTTACA GGAGGTATCT 
GATGAGGATG AAATTCTACC ACCAAAACTT CAAGCTGCCC TGATGCAGAT TTTGGAAGAA 
CGAAATGAAA TCTTGACTCA GGAGCAGAAT TTTTCACAAG ATGTGACACT CAACTCTCTG 
GTGTCCGAAG CATTTGTCAG GTTTTTTGTG GAGTTGGTAG GACATTATTC TTTGAACATG 
ACTGTCACTG AGCGTGGGGA GCGTGTTTTC CAAAGGGAAC CATTCCGTAA GTCCCACACC 
TCCCGAAGTG TACGCCACTT CCTGGATCTC TTCATGGAAA CTCAGATGTT TGCAGGATTC 
ATCCAGGACC GAGAGCTTCG GAAAAGTGGA GTTAAAGGTT TGTTTGAGAT CCGGGCCATC 
CAGTATTTGG AAACAATTCC TGAGTCGGAG CCCAGTGGGA TGAATAGAAT TTTGCGGAGT 
CTTGGAAGCA AAATGAAATT TCTGCAAAAG AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Common genetic variants on 1p13.2 associate with risk of autism.
Molecular psychiatry19(11)1212-9(2014 Nov)
Xia K,Guo H,Hu Z,Xun G,Zuo L,Peng Y,Wang K,He Y,Xiong Z,Sun L,Pan Q,Long Z,Zou X,Li X,Li W,Xu X,Lu L,Liu Y,Hu Y,Tian D,Long L,Ou J,Liu Y,Li X,Zhang L,Pan Y,Chen J,Peng H,Liu Q,Luo X,Su W,Wu L,Liang D,Dai H,Yan X,Feng Y,Tang B,Li J,Miedzybrodzka Z,Xia J,Zhang Z,Luo X,Zhang X,St Clair D,Zhao J,Zhang F

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.
The Journal of cell biology191(2)367-81(2010 Oct)
Yoshimura S,Gerondopoulos A,Linford A,Rigden DJ,Barr FA

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DENND2C cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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