gRNAs
The following SLFN5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLFN5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu30913 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_144975.3 , NM_144975.4 | |
| Accession Version | NM_144975.3 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2676bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-11-11 | |
| Organism | Homo sapiens(human) | |
| Product | schlafen family member 5 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP281007.1, BC125200.1, AC022706.7 and BX102817.1. On Apr 20, 2007 this sequence version replaced NM_144975.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.150548.1, SRR1660809.233387.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGAGTCTTA GGATTGATGT GGATACAAAC TTTCCTGAGT GTGTTGTAGA TGCAGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_659412.3 |
| CDS | 118..2793 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_144975.3 |
1 | ATGAGTCTTA GGATTGATGT GGATACAAAC TTTCCTGAGT GTGTTGTAGA TGCAGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu30913 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_144975.3 , NM_144975.4 | |
| Accession Version | NM_144975.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2676bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-26 | |
| Organism | Homo sapiens(human) | |
| Product | schlafen family member 5 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP281007.1, BC125200.1, AC022706.7 and BX102817.1. On Nov 23, 2018 this sequence version replaced NM_144975.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK303299.1, SRR1803611.150548.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000299977.9/ ENSP00000299977.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGAGTCTTA GGATTGATGT GGATACAAAC TTTCCTGAGT GTGTTGTAGA TGCAGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_659412.3 |
| CDS | 113..2788 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_144975.4 |
1 | ATGAGTCTTA GGATTGATGT GGATACAAAC TTTCCTGAGT GTGTTGTAGA TGCAGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu50159 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001330183.2 , NM_001330183.1 | |
| Accession Version | NM_001330183.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1170bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-27 | |
| Organism | Homo sapiens(human) | |
| Product | schlafen family member 5 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK303632.1, AC022706.7 and BQ023439.1. On May 31, 2019 this sequence version replaced NM_001330183.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.262725.1, AK303632.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGAGTCTTA GGATTGATGT GGATACAAAC TTTCCTGAGT GTGTTGTAGA TGCAGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001317112.1 |
| CDS | 113..1282 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001330183.2 |
1 | ATGAGTCTTA GGATTGATGT GGATACAAAC TTTCCTGAGT GTGTTGTAGA TGCAGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu50159 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001330183.2 , NM_001330183.1 | |
| Accession Version | NM_001330183.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1170bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-06-30 | |
| Organism | Homo sapiens(human) | |
| Product | schlafen family member 5 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC389067.1, AK303632.1, AC022706.7 and BQ023439.1. On Aug 18, 2016 this sequence version replaced XM_005257934.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.262725.1, AK303632.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGAGTCTTA GGATTGATGT GGATACAAAC TTTCCTGAGT GTGTTGTAGA TGCAGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001317112.1 |
| CDS | 149..1318 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001330183.1 |
1 | ATGAGTCTTA GGATTGATGT GGATACAAAC TTTCCTGAGT GTGTTGTAGA TGCAGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma. |
SCHLAFEN 5 expression correlates with intestinal metaplasia that progresses to gastric cancer. |
Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells. |
Role of interferon {alpha} (IFN{alpha})-inducible Schlafen-5 in regulation of anchorage-independent growth and invasion of malignant melanoma cells. |
Schlafen, a new family of growth regulatory genes that affect thymocyte development. |
