CSTL1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CSTL1
Entrez Gene ID	128817
Full Name	cystatin like 1
Synonyms	CTES1,RCET11,dJ322G13.4
General protein information	Preferred Names cystatin like 1 Names cystatin-like 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20p11.21
Summary	The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located at the telomeric end of the cystatin locus and encodes a type 2 cystatin-like protein. The specific function of this protein has not been determined. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_138283.1	NP_612140.1	cystatin-like 1 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CSTL1	XP_005634763.1
Homo sapiens (human)	CSTL1	NP_612140.1
Bos taurus (cattle)	CSTL1	XP_002692210.2
Pan troglodytes (chimpanzee)	CSTL1	XP_001146859.1
Rattus norvegicus (Norway rat)	Cstl1	NP_001099992.1
Mus musculus (house mouse)	Cstl1	NP_808323.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution and human tissue expression of the Cres/Testatin subgroup genes, a reproductive tissue specific subgroup of the type 2 cystatins.
Frygelius J, Arvestad L, Wedell A, T?h?nen V
Evolution & development12(3)329-42(2010 May-Jun)

The DNA sequence and comparative analysis of human chromosome 20.
Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, Stavrides G, Almeida JP, Babbage AK, Bagguley CL, Bailey J, Barlow KF, Bates KN, Beard LM, Beare DM, Beasley OP, Bird CP, Blakey SE, Bridgeman AM, Brown AJ, Buck D, Burrill W, Butler AP, Carder C, Carter NP, Chapman JC, Clamp M, Clark G, Clark LN, Clark SY, Clee CM, Clegg S, Cobley VE, Collier RE, Connor R, Corby NR, Coulson A, Coville GJ, Deadman R, Dhami P, Dunn M, Ellington AG, Frankland JA, Fraser A, French L, Garner P, Grafham DV, Griffiths C, Griffiths MN, Gwilliam R, Hall RE, Hammond S, Harley JL, Heath PD, Ho S, Holden JL, Howden PJ, Huckle E, Hunt AR, Hunt SE, Jekosch K, Johnson CM, Johnson D, Kay MP, Kimberley AM, King A, Knights A, Laird GK, Lawlor S, Lehvaslaiho MH, Leversha M, Lloyd C, Lloyd DM, Lovell JD, Marsh VL, Martin SL, McConnachie LJ, McLay K, McMurray AA, Milne S, Mistry D, Moore MJ, Mullikin JC, Nickerson T, Oliver K, Parker A, Patel R, Pearce TA, Peck AI, Phillimore BJ, Prathalingam SR, Plumb RW, Ramsay H, Rice CM, Ross MT, Scott CE, Sehra HK, Shownkeen R, Sims S, Skuce CD, Smith ML, Soderlund C, Steward CA, Sulston JE, Swann M, Sycamore N, Taylor R, Tee L, Thomas DW, Thorpe A, Tracey A, Tromans AC, Vaudin M, Wall M, Wallis JM, Whitehead SL, Whittaker P, Willey DL, Williams L, Williams SA, Wilming L, Wray PW, Hubbard T, Durbin RM, Bentley DR, Beck S, Rogers J
Nature414(6866)865-71(2001 Dec 20-27)

Friends and relations of the cystatin superfamily--new members and their evolution.
Brown WM, Dziegielewska KM
Protein science : a publication of the Protein Society6(1)5-12(1997 Jan)

Direct mapping of seven genes encoding human type 2 cystatins to a single site located at 20p11.2.
Dickinson DP, Zhao Y, Thiesse M, Siciliano MJ
Genomics24(1)172-5(1994 Nov)

The human type 2 cystatin gene family consists of eight to nine members, with at least seven genes clustered at a single locus on human chromosome 20.
Thiesse M, Millar SJ, Dickinson DP
DNA and cell biology13(2)97-116(1994 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CSTL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CSTL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu29318	NM_138283.1 Latest version!	Homo sapiens cystatin like 1 (CSTL1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CSTL1 ( NM_138283.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_612140.1 Homo sapiens cystatin like 1 (CSTL1), mRNA.

Price & Availability↑

CloneID	OHu29318
Clone ID Related Accession (Same CDS sequence)	NM_138283.1
Accession Version	NM_138283.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 438bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Homo sapiens(human)
Product	cystatin-like 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY707749.1. ##Evidence-Data-START## Transcript exon combination :: AY707749.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2151119 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGATCG GATGCTGGAG AAACCCCCTG CTGCTGCTGA TTGCCCTGGT CCTGTCAGCC 
AAGCTGGGTC ACTTCCAAAG GTGGGAGGGC TTCCAGCAGA AGCTCATGAG CAAGAAGAAC 
ATGAATTCAA CACTCAACTT CTTCATTCAA TCCTACAACA ATGCCAGCAA CGACACCTAC 
TTATATCGAG TCCAGAGGCT AATTCGAAGT CAGATGCAGC TGACGACGGG AGTGGAGTAT 
ATAGTCACTG TGAAGATTGG CTGGACCAAA TGCAAGAGGA ATGACACGAG CAATTCTTCC 
TGCCCCCTGC AAAGCAAGAA GCTGAGAAAG AGTTTAATTT GCGAGTCTTT GATATACACC 
ATGCCCTGGA TAAACTATTT CCAGCTCTGG AACAATTCCT GTCTGGAGGC CGAGCATGTG 
GGCAGAAACC TCAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612140.1
CDS	247..684
Translation	MGIGCWRNPLLLLIALVLSAKLGHFQRWEGFQQKLMSKKNMNSTLNFFIQSYNNASNDTYLYRVQRLIRSQMQLTTGVEYIVTVKIGWTKCKRNDTSNSSCPLQSKKLRKSLICESLIYTMPWINYFQLWNNSCLEAEHVGRNLR

Target ORF information:

RefSeq Version	NM_138283.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cystatin like 1 (CSTL1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138283.1

ORF Insert Sequence:

ATGGGGATCG GATGCTGGAG AAACCCCCTG CTGCTGCTGA TTGCCCTGGT CCTGTCAGCC 
AAGCTGGGTC ACTTCCAAAG GTGGGAGGGC TTCCAGCAGA AGCTCATGAG CAAGAAGAAC 
ATGAATTCAA CACTCAACTT CTTCATTCAA TCCTACAACA ATGCCAGCAA CGACACCTAC 
TTATATCGAG TCCAGAGGCT AATTCGAAGT CAGATGCAGC TGACGACGGG AGTGGAGTAT 
ATAGTCACTG TGAAGATTGG CTGGACCAAA TGCAAGAGGA ATGACACGAG CAATTCTTCC 
TGCCCCCTGC AAAGCAAGAA GCTGAGAAAG AGTTTAATTT GCGAGTCTTT GATATACACC 
ATGCCCTGGA TAAACTATTT CCAGCTCTGG AACAATTCCT GTCTGGAGGC CGAGCATGTG 
GGCAGAAACC TCAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution and human tissue expression of the Cres/Testatin subgroup genes, a reproductive tissue specific subgroup of the type 2 cystatins.
Evolution & development12(3)329-42(2010 May-Jun)
Frygelius J,Arvestad L,Wedell A,T?h?nen V

The DNA sequence and comparative analysis of human chromosome 20.
Nature414(6866)865-71(2001 Dec 20-27)
Deloukas P,Matthews LH,Ashurst J,Burton J,Gilbert JG,Jones M,Stavrides G,Almeida JP,Babbage AK,Bagguley CL,Bailey J,Barlow KF,Bates KN,Beard LM,Beare DM,Beasley OP,Bird CP,Blakey SE,Bridgeman AM,Brown AJ,Buck D,Burrill W,Butler AP,Carder C,Carter NP,Chapman JC,Clamp M,Clark G,Clark LN,Clark SY,Clee CM,Clegg S,Cobley VE,Collier RE,Connor R,Corby NR,Coulson A,Coville GJ,Deadman R,Dhami P,Dunn M,Ellington AG,Frankland JA,Fraser A,French L,Garner P,Grafham DV,Griffiths C,Griffiths MN,Gwilliam R,Hall RE,Hammond S,Harley JL,Heath PD,Ho S,Holden JL,Howden PJ,Huckle E,Hunt AR,Hunt SE,Jekosch K,Johnson CM,Johnson D,Kay MP,Kimberley AM,King A,Knights A,Laird GK,Lawlor S,Lehvaslaiho MH,Leversha M,Lloyd C,Lloyd DM,Lovell JD,Marsh VL,Martin SL,McConnachie LJ,McLay K,McMurray AA,Milne S,Mistry D,Moore MJ,Mullikin JC,Nickerson T,Oliver K,Parker A,Patel R,Pearce TA,Peck AI,Phillimore BJ,Prathalingam SR,Plumb RW,Ramsay H,Rice CM,Ross MT,Scott CE,Sehra HK,Shownkeen R,Sims S,Skuce CD,Smith ML,Soderlund C,Steward CA,Sulston JE,Swann M,Sycamore N,Taylor R,Tee L,Thomas DW,Thorpe A,Tracey A,Tromans AC,Vaudin M,Wall M,Wallis JM,Whitehead SL,Whittaker P,Willey DL,Williams L,Williams SA,Wilming L,Wray PW,Hubbard T,Durbin RM,Bentley DR,Beck S,Rogers J

Friends and relations of the cystatin superfamily--new members and their evolution.
Protein science : a publication of the Protein Society6(1)5-12(1997 Jan)
Brown WM,Dziegielewska KM

Direct mapping of seven genes encoding human type 2 cystatins to a single site located at 20p11.2.
Genomics24(1)172-5(1994 Nov)
Dickinson DP,Zhao Y,Thiesse M,Siciliano MJ

The human type 2 cystatin gene family consists of eight to nine members, with at least seven genes clustered at a single locus on human chromosome 20.
DNA and cell biology13(2)97-116(1994 Feb)
Thiesse M,Millar SJ,Dickinson DP

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CSTL1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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