CYP2U1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CYP2U1
Entrez Gene ID	113612
Full Name	cytochrome P450 family 2 subfamily U member 1
Synonyms	P450TEC,SPG49,SPG56
General protein information	Preferred Names cytochrome P450 family 2 subfamily U member 1 Names cytochrome P450 2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 spastic paraplegia 49
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q25
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. [provided by RefSeq, Jul 2008].
Disorder MIM:	610670
Disorder Html:	Spastic paraplegia 56, autosomal recessive, 615030 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_183075.3	NP_898898.1	cytochrome P450 2U1
XM_005262720.2	XP_005262777.1	cytochrome P450 2U1 isoform X2
NM_183075.2	NP_898898.1	cytochrome P450 2U1
XM_005262717.2	XP_005262774.1	cytochrome P450 2U1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC471267	XP_526649.2
Rattus norvegicus (Norway rat)	Cyp2u1	NP_001019950.1
Drosophila melanogaster (fruit fly)	Cyp18a1	NP_523403.2
Arabidopsis thaliana (thale cress)	FAH1	NP_195345.1
Xenopus tropicalis (tropical clawed frog)	cyp2u1	NP_001106471.1
Mus musculus (house mouse)	Cyp2u1	NP_082092.2
Gallus gallus (chicken)	LOC422528	XP_420491.3
Danio rerio (zebrafish)	cyp2u1	NP_001139036.1
Arabidopsis thaliana (thale cress)	AT5G04330	NP_196053.2
Homo sapiens (human)	CYP2U1	NP_898898.1
Canis lupus familiaris (dog)	CYP2U1	XP_005639392.1
Bos taurus (cattle)	CYP2U1	NP_001069518.1

Gene Ontology
Bibliography

Related articles in PubMed

CYP2U1 activity is altered by missense mutations in hereditary spastic paraplegia 56.
Durand CM, Dhers L, Tesson C, Tessa A, Fouillen L, Jacquer? S, Raymond L, Coupry I, Benard G, Darios F, El-Hachimi KH, Astrea G, Rivier F, Banneau G, Pujol C, Lacombe D, Durr A, Babin PJ, Santorelli FM, Pietrancosta N, Boucher JL, Mansuy D, Stevanin G, Goizet C
Human mutation39(1)140-151(2018 Jan)

An atypical case of SPG56/CYP2U1-related spastic paraplegia presenting with delayed myelination.
Minase G, Miyatake S, Nabatame S, Arai H, Koshimizu E, Mizuguchi T, Nakashima M, Miyake N, Saitsu H, Miyamoto T, Sengoku K, Matsumoto N
Journal of human genetics62(11)997-1000(2017 Nov)

Membrane-bound human orphan cytochrome P450 2U1: Sequence singularities, construction of a full 3D model, and substrate docking.
Ducassou L, Dhers L, Jonasson G, Pietrancosta N, Boucher JL, Mansuy D, Andr? F
Biochimie140166-175(2017 Sep)

Cytochrome P450 2U1, a very peculiar member of the human P450s family.
Dhers L, Ducassou L, Boucher JL, Mansuy D
Cellular and molecular life sciences : CMLS74(10)1859-1869(2017 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

protein sequence of CYP2U1 displayed two unique characteristics when compared to those of the human CYPs, the presence of a longer N-terminal region upstream of the putative trans-membrane helix (TMH) containing 8 proline residues, and of an insert of about 20 amino acids containing 5 arginine residues between helices A' and A
Title: Membrane-bound human orphan cytochrome P450 2U1: Sequence singularities, construction of a full 3D model, and substrate docking.

Cytochrome P450 2U1 (CYP2U1) exhibits several distinctive characteristics among the 57 human CYPs, such as its presence in almost all living organisms with a highly conserved sequence, its particular gene organization with only five exons, its major location in thymus and brain, and its protein sequence involving an unusually long N-terminal region containing 8 proline residues. [review]
Title: Cytochrome P450 2U1, a very peculiar member of the human P450s family.

the mode of interaction of several Fe(III)-heme ligands and substrates with the active site of CYP2U1 on the basis of spectroscopic and molecular docking data.[CYP2U1]
Title: Spectral and 3D model studies of the interaction of orphan human cytochrome P450 2U1 with substrates and ligands.

we identified two novel mutations in CYP2U1 in two unrelated Hereditary spastic paraplegia patients by whole exome sequencing
Title: CYP2U1 mutations in two ian patients with activity induced dystonia, motor regression and spastic paraplegia.

This is the first formal report of pigmentary degenerative maculopathy associated with a CYP2U1 homozygous mutation
Title: Pigmentary degenerative maculopathy as prominent phenotype in an Italian SPG56/CYP2U1 family.

The following CYP2U1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP2U1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18230	NM_183075.3 Latest version!	Homo sapiens cytochrome P450 family 2 subfamily U member 1 (CYP2U1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu38691	XM_005262717.2 Latest version!	Homo sapiens cytochrome P450 family 2 subfamily U member 1 (CYP2U1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu38692	XM_005262720.2 Latest version!	Homo sapiens cytochrome P450 family 2 subfamily U member 1 (CYP2U1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu18230	NM_183075.2	Homo sapiens cytochrome P450 family 2 subfamily U member 1 (CYP2U1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CYP2U1 ( NM_183075.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_898898.1 Homo sapiens cytochrome P450 family 2 subfamily U member 1 (CYP2U1), mRNA.

Price & Availability↑

CloneID	OHu18230
Clone ID Related Accession (Same CDS sequence)	NM_183075.3 , NM_183075.2
Accession Version	NM_183075.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1635bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	cytochrome P450 2U1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC096564.3, BX437421.2, AY343323.1, BX354124.2, AK026498.1, CD672608.1, BU838483.1 and AC114733.4. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_183075.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.135482.1, SRR1803617.264842.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000332884.11/ ENSP00000333212.6 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGTCTC CGGGGCCGTC GCAGCCGCCG GCCGAGGACC CGCCCTGGCC CGCGCGCCTC 
CTGCGTGCGC CTCTGGGGCT GCTGCGGCTG GACCCCAGCG GGGGCGCGCT GCTGCTATGC 
GGCCTCGTAG CGCTGCTGGG CTGGAGCTGG CTGCGGAGGC GCCGGGCGCG GGGCATCCCG 
CCCGGGCCCA CGCCCTGGCC TCTGGTGGGC AACTTCGGTC ACGTGCTGCT GCCTCCCTTC 
CTCCGGCGGC GGAGCTGGCT GAGCAGCAGG ACCAGGGCCG CAGGGATTGA TCCCTCGGTC 
ATAGGCCCGC AGGTGCTCCT GGCTCACCTA GCCCGCGTGT ACGGCAGCAT CTTCAGCTTC 
TTTATCGGCC ACTACCTGGT GGTGGTCCTC AGCGACTTCC ACAGCGTGCG CGAGGCGCTG 
GTGCAGCAGG CCGAGGTCTT CAGCGACCGC CCGCGGGTGC CGCTCATCTC CATCGTGACC 
AAGGAGAAGG GGGTTGTGTT TGCACATTAT GGTCCCGTCT GGAGACAACA AAGGAAGTTC 
TCTCATTCAA CTCTTCGTCA TTTTGGGTTG GGAAAACTTA GCTTGGAGCC CAAGATTATT 
GAGGAGTTCA AATATGTGAA AGCAGAAATG CAAAAGCACG GAGAAGACCC CTTCTGCCCT 
TTCTCCATCA TCAGCAATGC CGTCTCTAAC ATCATTTGCT CCTTGTGCTT TGGCCAGCGC 
TTTGATTACA CTAATAGTGA GTTCAAGAAA ATGCTTGGTT TTATGTCACG AGGCCTAGAA 
ATCTGTCTGA ACAGTCAAGT CCTCCTGGTC AACATATGCC CTTGGCTTTA TTACCTTCCC 
TTTGGACCAT TTAAGGAATT AAGACAAATT GAAAAGGATA TAACCAGTTT CCTTAAAAAA 
ATCATCAAAG ACCATCAAGA GTCTCTGGAT AGAGAGAACC CTCAGGACTT CATAGACATG 
TACCTTCTCC ACATGGAAGA GGAGAGGAAA AATAATAGTA ACAGCAGTTT TGATGAAGAG 
TACTTATTTT ATATCATTGG GGATCTCTTT ATTGCTGGGA CTGATACCAC AACTAACTCT 
TTGCTCTGGT GCCTGCTGTA TATGTCGCTG AACCCCGATG TACAAGAAAA GGTTCATGAA 
GAAATTGAAA GAGTCATTGG CGCCAACCGA GCTCCTTCCC TCACAGACAA GGCCCAGATG 
CCCTACACAG AAGCCACCAT CATGGAAGTG CAGAGGCTAA CTGTGGTGGT GCCGCTTGCC 
ATTCCTCATA TGACCTCAGA GAACACAGTG CTCCAAGGGT ATACCATTCC TAAAGGCACA 
TTGATCTTAC CCAACCTGTG GTCAGTACAT AGAGACCCAG CCATTTGGGA GAAACCGGAG 
GATTTCTACC CTAATCGATT TCTGGATGAC CAAGGACAAC TAATTAAAAA AGAAACCTTT 
ATTCCTTTTG GGATAGGGAA GCGGGTGTGT ATGGGAGAAC AACTGGCAAA GATGGAATTA 
TTCCTAATGT TTGTGAGCCT AATGCAGAGT TTCGCATTTG CTTTACCTGA GGATTCTAAG 
AAGCCCCTCC TGACTGGAAG ATTTGGTCTA ACTTTAGCCC CACATCCATT TAATATAACT 
ATTTCAAGGA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_898898.1
CDS	96..1730
Translation	MSSPGPSQPPAEDPPWPARLLRAPLGLLRLDPSGGALLLCGLVALLGWSWLRRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKEKGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFSIISNAVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWLYYLPFGPFKELRQIEKDITSFLKKIIKDHQESLDRENPQDFIDMYLLHMEEERKNNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSKKPLLTGRFGLTLAPHPFNITISRR

Target ORF information:

RefSeq Version	NM_183075.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily U member 1 (CYP2U1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_183075.3

ORF Insert Sequence:

ATGTCGTCTC CGGGGCCGTC GCAGCCGCCG GCCGAGGACC CGCCCTGGCC CGCGCGCCTC 
CTGCGTGCGC CTCTGGGGCT GCTGCGGCTG GACCCCAGCG GGGGCGCGCT GCTGCTATGC 
GGCCTCGTAG CGCTGCTGGG CTGGAGCTGG CTGCGGAGGC GCCGGGCGCG GGGCATCCCG 
CCCGGGCCCA CGCCCTGGCC TCTGGTGGGC AACTTCGGTC ACGTGCTGCT GCCTCCCTTC 
CTCCGGCGGC GGAGCTGGCT GAGCAGCAGG ACCAGGGCCG CAGGGATTGA TCCCTCGGTC 
ATAGGCCCGC AGGTGCTCCT GGCTCACCTA GCCCGCGTGT ACGGCAGCAT CTTCAGCTTC 
TTTATCGGCC ACTACCTGGT GGTGGTCCTC AGCGACTTCC ACAGCGTGCG CGAGGCGCTG 
GTGCAGCAGG CCGAGGTCTT CAGCGACCGC CCGCGGGTGC CGCTCATCTC CATCGTGACC 
AAGGAGAAGG GGGTTGTGTT TGCACATTAT GGTCCCGTCT GGAGACAACA AAGGAAGTTC 
TCTCATTCAA CTCTTCGTCA TTTTGGGTTG GGAAAACTTA GCTTGGAGCC CAAGATTATT 
GAGGAGTTCA AATATGTGAA AGCAGAAATG CAAAAGCACG GAGAAGACCC CTTCTGCCCT 
TTCTCCATCA TCAGCAATGC CGTCTCTAAC ATCATTTGCT CCTTGTGCTT TGGCCAGCGC 
TTTGATTACA CTAATAGTGA GTTCAAGAAA ATGCTTGGTT TTATGTCACG AGGCCTAGAA 
ATCTGTCTGA ACAGTCAAGT CCTCCTGGTC AACATATGCC CTTGGCTTTA TTACCTTCCC 
TTTGGACCAT TTAAGGAATT AAGACAAATT GAAAAGGATA TAACCAGTTT CCTTAAAAAA 
ATCATCAAAG ACCATCAAGA GTCTCTGGAT AGAGAGAACC CTCAGGACTT CATAGACATG 
TACCTTCTCC ACATGGAAGA GGAGAGGAAA AATAATAGTA ACAGCAGTTT TGATGAAGAG 
TACTTATTTT ATATCATTGG GGATCTCTTT ATTGCTGGGA CTGATACCAC AACTAACTCT 
TTGCTCTGGT GCCTGCTGTA TATGTCGCTG AACCCCGATG TACAAGAAAA GGTTCATGAA 
GAAATTGAAA GAGTCATTGG CGCCAACCGA GCTCCTTCCC TCACAGACAA GGCCCAGATG 
CCCTACACAG AAGCCACCAT CATGGAAGTG CAGAGGCTAA CTGTGGTGGT GCCGCTTGCC 
ATTCCTCATA TGACCTCAGA GAACACAGTG CTCCAAGGGT ATACCATTCC TAAAGGCACA 
TTGATCTTAC CCAACCTGTG GTCAGTACAT AGAGACCCAG CCATTTGGGA GAAACCGGAG 
GATTTCTACC CTAATCGATT TCTGGATGAC CAAGGACAAC TAATTAAAAA AGAAACCTTT 
ATTCCTTTTG GGATAGGGAA GCGGGTGTGT ATGGGAGAAC AACTGGCAAA GATGGAATTA 
TTCCTAATGT TTGTGAGCCT AATGCAGAGT TTCGCATTTG CTTTACCTGA GGATTCTAAG 
AAGCCCCTCC TGACTGGAAG ATTTGGTCTA ACTTTAGCCC CACATCCATT TAATATAACT 
ATTTCAAGGA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2U1 ( NM_183075.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_898898.1 Homo sapiens cytochrome P450 family 2 subfamily U member 1 (CYP2U1), mRNA.

Price & Availability↑

CloneID	OHu18230
Clone ID Related Accession (Same CDS sequence)	NM_183075.3 , NM_183075.2
Accession Version	NM_183075.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1635bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-11
Organism	Homo sapiens(human)
Product	cytochrome P450 2U1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX437421.2, AY343323.1, BX354124.2, AK026498.1, CD672608.1 and BU838483.1. This sequence is a reference standard in the RefSeqGene project. On Apr 28, 2005 this sequence version replaced NM_183075.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.135482.1, SRR1803617.264842.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGTCTC CGGGGCCGTC GCAGCCGCCG GCCGAGGACC CGCCCTGGCC CGCGCGCCTC 
CTGCGTGCGC CTCTGGGGCT GCTGCGGCTG GACCCCAGCG GGGGCGCGCT GCTGCTATGC 
GGCCTCGTAG CGCTGCTGGG CTGGAGCTGG CTGCGGAGGC GCCGGGCGCG GGGCATCCCG 
CCCGGGCCCA CGCCCTGGCC TCTGGTGGGC AACTTCGGTC ACGTGCTGCT GCCTCCCTTC 
CTCCGGCGGC GGAGCTGGCT GAGCAGCAGG ACCAGGGCCG CAGGGATTGA TCCCTCGGTC 
ATAGGCCCGC AGGTGCTCCT GGCTCACCTA GCCCGCGTGT ACGGCAGCAT CTTCAGCTTC 
TTTATCGGCC ACTACCTGGT GGTGGTCCTC AGCGACTTCC ACAGCGTGCG CGAGGCGCTG 
GTGCAGCAGG CCGAGGTCTT CAGCGACCGC CCGCGGGTGC CGCTCATCTC CATCGTGACC 
AAGGAGAAGG GGGTTGTGTT TGCACATTAT GGTCCCGTCT GGAGACAACA AAGGAAGTTC 
TCTCATTCAA CTCTTCGTCA TTTTGGGTTG GGAAAACTTA GCTTGGAGCC CAAGATTATT 
GAGGAGTTCA AATATGTGAA AGCAGAAATG CAAAAGCACG GAGAAGACCC CTTCTGCCCT 
TTCTCCATCA TCAGCAATGC CGTCTCTAAC ATCATTTGCT CCTTGTGCTT TGGCCAGCGC 
TTTGATTACA CTAATAGTGA GTTCAAGAAA ATGCTTGGTT TTATGTCACG AGGCCTAGAA 
ATCTGTCTGA ACAGTCAAGT CCTCCTGGTC AACATATGCC CTTGGCTTTA TTACCTTCCC 
TTTGGACCAT TTAAGGAATT AAGACAAATT GAAAAGGATA TAACCAGTTT CCTTAAAAAA 
ATCATCAAAG ACCATCAAGA GTCTCTGGAT AGAGAGAACC CTCAGGACTT CATAGACATG 
TACCTTCTCC ACATGGAAGA GGAGAGGAAA AATAATAGTA ACAGCAGTTT TGATGAAGAG 
TACTTATTTT ATATCATTGG GGATCTCTTT ATTGCTGGGA CTGATACCAC AACTAACTCT 
TTGCTCTGGT GCCTGCTGTA TATGTCGCTG AACCCCGATG TACAAGAAAA GGTTCATGAA 
GAAATTGAAA GAGTCATTGG CGCCAACCGA GCTCCTTCCC TCACAGACAA GGCCCAGATG 
CCCTACACAG AAGCCACCAT CATGGAAGTG CAGAGGCTAA CTGTGGTGGT GCCGCTTGCC 
ATTCCTCATA TGACCTCAGA GAACACAGTG CTCCAAGGGT ATACCATTCC TAAAGGCACA 
TTGATCTTAC CCAACCTGTG GTCAGTACAT AGAGACCCAG CCATTTGGGA GAAACCGGAG 
GATTTCTACC CTAATCGATT TCTGGATGAC CAAGGACAAC TAATTAAAAA AGAAACCTTT 
ATTCCTTTTG GGATAGGGAA GCGGGTGTGT ATGGGAGAAC AACTGGCAAA GATGGAATTA 
TTCCTAATGT TTGTGAGCCT AATGCAGAGT TTCGCATTTG CTTTACCTGA GGATTCTAAG 
AAGCCCCTCC TGACTGGAAG ATTTGGTCTA ACTTTAGCCC CACATCCATT TAATATAACT 
ATTTCAAGGA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_898898.1
CDS	84..1718
Translation	MSSPGPSQPPAEDPPWPARLLRAPLGLLRLDPSGGALLLCGLVALLGWSWLRRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKEKGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFSIISNAVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWLYYLPFGPFKELRQIEKDITSFLKKIIKDHQESLDRENPQDFIDMYLLHMEEERKNNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSKKPLLTGRFGLTLAPHPFNITISRR

Target ORF information:

RefSeq Version	NM_183075.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily U member 1 (CYP2U1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_183075.2

ORF Insert Sequence:

ATGTCGTCTC CGGGGCCGTC GCAGCCGCCG GCCGAGGACC CGCCCTGGCC CGCGCGCCTC 
CTGCGTGCGC CTCTGGGGCT GCTGCGGCTG GACCCCAGCG GGGGCGCGCT GCTGCTATGC 
GGCCTCGTAG CGCTGCTGGG CTGGAGCTGG CTGCGGAGGC GCCGGGCGCG GGGCATCCCG 
CCCGGGCCCA CGCCCTGGCC TCTGGTGGGC AACTTCGGTC ACGTGCTGCT GCCTCCCTTC 
CTCCGGCGGC GGAGCTGGCT GAGCAGCAGG ACCAGGGCCG CAGGGATTGA TCCCTCGGTC 
ATAGGCCCGC AGGTGCTCCT GGCTCACCTA GCCCGCGTGT ACGGCAGCAT CTTCAGCTTC 
TTTATCGGCC ACTACCTGGT GGTGGTCCTC AGCGACTTCC ACAGCGTGCG CGAGGCGCTG 
GTGCAGCAGG CCGAGGTCTT CAGCGACCGC CCGCGGGTGC CGCTCATCTC CATCGTGACC 
AAGGAGAAGG GGGTTGTGTT TGCACATTAT GGTCCCGTCT GGAGACAACA AAGGAAGTTC 
TCTCATTCAA CTCTTCGTCA TTTTGGGTTG GGAAAACTTA GCTTGGAGCC CAAGATTATT 
GAGGAGTTCA AATATGTGAA AGCAGAAATG CAAAAGCACG GAGAAGACCC CTTCTGCCCT 
TTCTCCATCA TCAGCAATGC CGTCTCTAAC ATCATTTGCT CCTTGTGCTT TGGCCAGCGC 
TTTGATTACA CTAATAGTGA GTTCAAGAAA ATGCTTGGTT TTATGTCACG AGGCCTAGAA 
ATCTGTCTGA ACAGTCAAGT CCTCCTGGTC AACATATGCC CTTGGCTTTA TTACCTTCCC 
TTTGGACCAT TTAAGGAATT AAGACAAATT GAAAAGGATA TAACCAGTTT CCTTAAAAAA 
ATCATCAAAG ACCATCAAGA GTCTCTGGAT AGAGAGAACC CTCAGGACTT CATAGACATG 
TACCTTCTCC ACATGGAAGA GGAGAGGAAA AATAATAGTA ACAGCAGTTT TGATGAAGAG 
TACTTATTTT ATATCATTGG GGATCTCTTT ATTGCTGGGA CTGATACCAC AACTAACTCT 
TTGCTCTGGT GCCTGCTGTA TATGTCGCTG AACCCCGATG TACAAGAAAA GGTTCATGAA 
GAAATTGAAA GAGTCATTGG CGCCAACCGA GCTCCTTCCC TCACAGACAA GGCCCAGATG 
CCCTACACAG AAGCCACCAT CATGGAAGTG CAGAGGCTAA CTGTGGTGGT GCCGCTTGCC 
ATTCCTCATA TGACCTCAGA GAACACAGTG CTCCAAGGGT ATACCATTCC TAAAGGCACA 
TTGATCTTAC CCAACCTGTG GTCAGTACAT AGAGACCCAG CCATTTGGGA GAAACCGGAG 
GATTTCTACC CTAATCGATT TCTGGATGAC CAAGGACAAC TAATTAAAAA AGAAACCTTT 
ATTCCTTTTG GGATAGGGAA GCGGGTGTGT ATGGGAGAAC AACTGGCAAA GATGGAATTA 
TTCCTAATGT TTGTGAGCCT AATGCAGAGT TTCGCATTTG CTTTACCTGA GGATTCTAAG 
AAGCCCCTCC TGACTGGAAG ATTTGGTCTA ACTTTAGCCC CACATCCATT TAATATAACT 
ATTTCAAGGA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2U1 ( XM_005262717.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005262774.1 Homo sapiens cytochrome P450 family 2 subfamily U member 1 (CYP2U1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu38691
Clone ID Related Accession (Same CDS sequence)	XM_005262717.2
Accession Version	XM_005262717.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1689bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cytochrome P450 2U1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005262717.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGTCTC CGGGGCCGTC GCAGCCGCCG GCCGAGGACC CGCCCTGGCC CGCGCGCCTC 
CTGCGTGCGC CTCTGGGGCT GCTGCGGCTG GACCCCAGCG GGGGCGCGCT GCTGCTATGC 
GGCCTCGTAG CGCTGCTGGG CTGGAGCTGG CTGCGGAGGC GCCGGGCGCG GGGCATCCCG 
CCCGGGCCCA CGCCCTGGCC TCTGGTGGGC AACTTCGGTC ACGTGCTGCT GCCTCCCTTC 
CTCCGGCGGC GGAGCTGGCT GAGCAGCAGG ACCAGGGCCG CAGGGATTGA TCCCTCGGTC 
ATAGGCCCGC AGGTGCTCCT GGCTCACCTA GCCCGCGTGT ACGGCAGCAT CTTCAGCTTC 
TTTATCGGCC ACTACCTGGT GGTGGTCCTC AGCGACTTCC ACAGCGTGCG CGAGGCGCTG 
GTGCAGCAGG CCGAGGTCTT CAGCGACCGC CCGCGGGTGC CGCTCATCTC CATCGTGACC 
AAGGAGAAGG GTGAGCGGGA GGTCGTGGGC TGTGGGTACG CGGATGCCGC GGATGAGTCT 
CCAGGGGTTG TGTTTGCACA TTATGGTCCC GTCTGGAGAC AACAAAGGAA GTTCTCTCAT 
TCAACTCTTC GTCATTTTGG GTTGGGAAAA CTTAGCTTGG AGCCCAAGAT TATTGAGGAG 
TTCAAATATG TGAAAGCAGA AATGCAAAAG CACGGAGAAG ACCCCTTCTG CCCTTTCTCC 
ATCATCAGCA ATGCCGTCTC TAACATCATT TGCTCCTTGT GCTTTGGCCA GCGCTTTGAT 
TACACTAATA GTGAGTTCAA GAAAATGCTT GGTTTTATGT CACGAGGCCT AGAAATCTGT 
CTGAACAGTC AAGTCCTCCT GGTCAACATA TGCCCTTGGC TTTATTACCT TCCCTTTGGA 
CCATTTAAGG AATTAAGACA AATTGAAAAG GATATAACCA GTTTCCTTAA AAAAATCATC 
AAAGACCATC AAGAGTCTCT GGATAGAGAG AACCCTCAGG ACTTCATAGA CATGTACCTT 
CTCCACATGG AAGAGGAGAG GAAAAATAAT AGTAACAGCA GTTTTGATGA AGAGTACTTA 
TTTTATATCA TTGGGGATCT CTTTATTGCT GGGACTGATA CCACAACTAA CTCTTTGCTC 
TGGTGCCTGC TGTATATGTC GCTGAACCCC GATGTACAAG AAAAGGTTCA TGAAGAAATT 
GAAAGAGTCA TTGGCGCCAA CCGAGCTCCT TCCCTCACAG ACAAGGCCCA GATGCCCTAC 
ACAGAAGCCA CCATCATGGA AGTGCAGAGG CTAACTGTGG TGGTGCCGCT TGCCATTCCT 
CATATGACCT CAGAGAACAC AGTGCTCCAA GGGTATACCA TTCCTAAAGG CACATTGATC 
TTACCCAACC TGTGGTCAGT ACATAGAGAC CCAGCCATTT GGGAGAAACC GGAGGATTTC 
TACCCTAATC GATTTCTGGA TGACCAAGGA CAACTAATTA AAAAAGAAAC CTTTATTCCT 
TTTGGGATAG GGAAGCGGGT GTGTATGGGA GAACAACTGG CAAAGATGGA ATTATTCCTA 
ATGTTTGTGA GCCTAATGCA GAGTTTCGCA TTTGCTTTAC CTGAGGATTC TAAGAAGCCC 
CTCCTGACTG GAAGATTTGG TCTAACTTTA GCCCCACATC CATTTAATAT AACTATTTCA 
AGGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005262774.1
CDS	96..1784
Translation	MSSPGPSQPPAEDPPWPARLLRAPLGLLRLDPSGGALLLCGLVALLGWSWLRRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKEKGEREVVGCGYADAADESPGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFSIISNAVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWLYYLPFGPFKELRQIEKDITSFLKKIIKDHQESLDRENPQDFIDMYLLHMEEERKNNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSKKPLLTGRFGLTLAPHPFNITISRR

Target ORF information:

RefSeq Version	XM_005262717.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily U member 1 (CYP2U1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005262717.2

ORF Insert Sequence:

ATGTCGTCTC CGGGGCCGTC GCAGCCGCCG GCCGAGGACC CGCCCTGGCC CGCGCGCCTC 
CTGCGTGCGC CTCTGGGGCT GCTGCGGCTG GACCCCAGCG GGGGCGCGCT GCTGCTATGC 
GGCCTCGTAG CGCTGCTGGG CTGGAGCTGG CTGCGGAGGC GCCGGGCGCG GGGCATCCCG 
CCCGGGCCCA CGCCCTGGCC TCTGGTGGGC AACTTCGGTC ACGTGCTGCT GCCTCCCTTC 
CTCCGGCGGC GGAGCTGGCT GAGCAGCAGG ACCAGGGCCG CAGGGATTGA TCCCTCGGTC 
ATAGGCCCGC AGGTGCTCCT GGCTCACCTA GCCCGCGTGT ACGGCAGCAT CTTCAGCTTC 
TTTATCGGCC ACTACCTGGT GGTGGTCCTC AGCGACTTCC ACAGCGTGCG CGAGGCGCTG 
GTGCAGCAGG CCGAGGTCTT CAGCGACCGC CCGCGGGTGC CGCTCATCTC CATCGTGACC 
AAGGAGAAGG GTGAGCGGGA GGTCGTGGGC TGTGGGTACG CGGATGCCGC GGATGAGTCT 
CCAGGGGTTG TGTTTGCACA TTATGGTCCC GTCTGGAGAC AACAAAGGAA GTTCTCTCAT 
TCAACTCTTC GTCATTTTGG GTTGGGAAAA CTTAGCTTGG AGCCCAAGAT TATTGAGGAG 
TTCAAATATG TGAAAGCAGA AATGCAAAAG CACGGAGAAG ACCCCTTCTG CCCTTTCTCC 
ATCATCAGCA ATGCCGTCTC TAACATCATT TGCTCCTTGT GCTTTGGCCA GCGCTTTGAT 
TACACTAATA GTGAGTTCAA GAAAATGCTT GGTTTTATGT CACGAGGCCT AGAAATCTGT 
CTGAACAGTC AAGTCCTCCT GGTCAACATA TGCCCTTGGC TTTATTACCT TCCCTTTGGA 
CCATTTAAGG AATTAAGACA AATTGAAAAG GATATAACCA GTTTCCTTAA AAAAATCATC 
AAAGACCATC AAGAGTCTCT GGATAGAGAG AACCCTCAGG ACTTCATAGA CATGTACCTT 
CTCCACATGG AAGAGGAGAG GAAAAATAAT AGTAACAGCA GTTTTGATGA AGAGTACTTA 
TTTTATATCA TTGGGGATCT CTTTATTGCT GGGACTGATA CCACAACTAA CTCTTTGCTC 
TGGTGCCTGC TGTATATGTC GCTGAACCCC GATGTACAAG AAAAGGTTCA TGAAGAAATT 
GAAAGAGTCA TTGGCGCCAA CCGAGCTCCT TCCCTCACAG ACAAGGCCCA GATGCCCTAC 
ACAGAAGCCA CCATCATGGA AGTGCAGAGG CTAACTGTGG TGGTGCCGCT TGCCATTCCT 
CATATGACCT CAGAGAACAC AGTGCTCCAA GGGTATACCA TTCCTAAAGG CACATTGATC 
TTACCCAACC TGTGGTCAGT ACATAGAGAC CCAGCCATTT GGGAGAAACC GGAGGATTTC 
TACCCTAATC GATTTCTGGA TGACCAAGGA CAACTAATTA AAAAAGAAAC CTTTATTCCT 
TTTGGGATAG GGAAGCGGGT GTGTATGGGA GAACAACTGG CAAAGATGGA ATTATTCCTA 
ATGTTTGTGA GCCTAATGCA GAGTTTCGCA TTTGCTTTAC CTGAGGATTC TAAGAAGCCC 
CTCCTGACTG GAAGATTTGG TCTAACTTTA GCCCCACATC CATTTAATAT AACTATTTCA 
AGGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2U1 ( XM_005262720.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005262777.1 Homo sapiens cytochrome P450 family 2 subfamily U member 1 (CYP2U1), transcript variant X2, mRNA.

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CloneID	OHu38692
Clone ID Related Accession (Same CDS sequence)	XM_005262720.2
Accession Version	XM_005262720.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cytochrome P450 2U1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005262720.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGTCTC CGGGGCCGTC GCAGCCGCCG GCCGAGGACC CGCCCTGGCC CGCGCGCCTC 
CTGCGTGCGC CTCTGGGGCT GCTGCGGCTG GACCCCAGCG GGGGCGCGCT GCTGCTATGC 
GGCCTCGTAG CGCTGCTGGG CTGGAGCTGG CTGCGGAGGC GCCGGGCGCG GGGCATCCCG 
CCCGGGCCCA CGCCCTGGCC TCTGGTGGGC AACTTCGGTC ACGTGCTGCT GCCTCCCTTC 
CTCCGGCGGC GGAGCTGGCT GAGCAGCAGG ACCAGGGCCG CAGGGATTGA TCCCTCGGTC 
ATAGGCCCGC AGGTGCTCCT GGCTCACCTA GCCCGCGTGT ACGGCAGCAT CTTCAGCTTC 
TTTATCGGCC ACTACCTGGT GGTGGTCCTC AGCGACTTCC ACAGCGTGCG CGAGGCGCTG 
GTGCAGCAGG CCGAGGTCTT CAGCGACCGC CCGCGGGTGC CGCTCATCTC CATCGTGACC 
AAGGAGAAGG AAAAGGTTCA TGAAGAAATT GAAAGAGTCA TTGGCGCCAA CCGAGCTCCT 
TCCCTCACAG ACAAGGCCCA GATGCCCTAC ACAGAAGCCA CCATCATGGA AGTGCAGAGG 
CTAACTGTGG TGGTGCCGCT TGCCATTCCT CATATGACCT CAGAGAACAC AGTGCTCCAA 
GGGTATACCA TTCCTAAAGG CACATTGATC TTACCCAACC TGTGGTCAGT ACATAGAGAC 
CCAGCCATTT GGGAGAAACC GGAGGATTTC TACCCTAATC GATTTCTGGA TGACCAAGGA 
CAACTAATTA AAAAAGAAAC CTTTATTCCT TTTGGGATAG GGAAGCGGGT GTGTATGGGA 
GAACAACTGG CAAAGATGGA ATTATTCCTA ATGTTTGTGA GCCTAATGCA GAGTTTCGCA 
TTTGCTTTAC CTGAGGATTC TAAGAAGCCC CTCCTGACTG GAAGATTTGG TCTAACTTTA 
GCCCCACATC CATTTAATAT AACTATTTCA AGGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005262777.1
CDS	96..1094
Translation	MSSPGPSQPPAEDPPWPARLLRAPLGLLRLDPSGGALLLCGLVALLGWSWLRRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKEKEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSKKPLLTGRFGLTLAPHPFNITISRR

Target ORF information:

RefSeq Version	XM_005262720.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily U member 1 (CYP2U1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005262720.2

ORF Insert Sequence:

ATGTCGTCTC CGGGGCCGTC GCAGCCGCCG GCCGAGGACC CGCCCTGGCC CGCGCGCCTC 
CTGCGTGCGC CTCTGGGGCT GCTGCGGCTG GACCCCAGCG GGGGCGCGCT GCTGCTATGC 
GGCCTCGTAG CGCTGCTGGG CTGGAGCTGG CTGCGGAGGC GCCGGGCGCG GGGCATCCCG 
CCCGGGCCCA CGCCCTGGCC TCTGGTGGGC AACTTCGGTC ACGTGCTGCT GCCTCCCTTC 
CTCCGGCGGC GGAGCTGGCT GAGCAGCAGG ACCAGGGCCG CAGGGATTGA TCCCTCGGTC 
ATAGGCCCGC AGGTGCTCCT GGCTCACCTA GCCCGCGTGT ACGGCAGCAT CTTCAGCTTC 
TTTATCGGCC ACTACCTGGT GGTGGTCCTC AGCGACTTCC ACAGCGTGCG CGAGGCGCTG 
GTGCAGCAGG CCGAGGTCTT CAGCGACCGC CCGCGGGTGC CGCTCATCTC CATCGTGACC 
AAGGAGAAGG AAAAGGTTCA TGAAGAAATT GAAAGAGTCA TTGGCGCCAA CCGAGCTCCT 
TCCCTCACAG ACAAGGCCCA GATGCCCTAC ACAGAAGCCA CCATCATGGA AGTGCAGAGG 
CTAACTGTGG TGGTGCCGCT TGCCATTCCT CATATGACCT CAGAGAACAC AGTGCTCCAA 
GGGTATACCA TTCCTAAAGG CACATTGATC TTACCCAACC TGTGGTCAGT ACATAGAGAC 
CCAGCCATTT GGGAGAAACC GGAGGATTTC TACCCTAATC GATTTCTGGA TGACCAAGGA 
CAACTAATTA AAAAAGAAAC CTTTATTCCT TTTGGGATAG GGAAGCGGGT GTGTATGGGA 
GAACAACTGG CAAAGATGGA ATTATTCCTA ATGTTTGTGA GCCTAATGCA GAGTTTCGCA 
TTTGCTTTAC CTGAGGATTC TAAGAAGCCC CTCCTGACTG GAAGATTTGG TCTAACTTTA 
GCCCCACATC CATTTAATAT AACTATTTCA AGGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CYP2U1 activity is altered by missense mutations in hereditary spastic paraplegia 56.
Human mutation39(1)140-151(2018 Jan)
Durand CM,Dhers L,Tesson C,Tessa A,Fouillen L,Jacquer? S,Raymond L,Coupry I,Benard G,Darios F,El-Hachimi KH,Astrea G,Rivier F,Banneau G,Pujol C,Lacombe D,Durr A,Babin PJ,Santorelli FM,Pietrancosta N,Boucher JL,Mansuy D,Stevanin G,Goizet C

An atypical case of SPG56/CYP2U1-related spastic paraplegia presenting with delayed myelination.
Journal of human genetics62(11)997-1000(2017 Nov)
Minase G,Miyatake S,Nabatame S,Arai H,Koshimizu E,Mizuguchi T,Nakashima M,Miyake N,Saitsu H,Miyamoto T,Sengoku K,Matsumoto N

Membrane-bound human orphan cytochrome P450 2U1: Sequence singularities, construction of a full 3D model, and substrate docking.
Biochimie140166-175(2017 Sep)
Ducassou L,Dhers L,Jonasson G,Pietrancosta N,Boucher JL,Mansuy D,Andr? F

Cytochrome P450 2U1, a very peculiar member of the human P450s family.
Cellular and molecular life sciences : CMLS74(10)1859-1869(2017 May)
Dhers L,Ducassou L,Boucher JL,Mansuy D

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CYP2U1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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