IRAK3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IRAK3
Entrez Gene ID	11213
Full Name	interleukin 1 receptor associated kinase 3
Synonyms	ASRT5,IRAKM
General protein information	Preferred Names interleukin 1 receptor associated kinase 3 Names interleukin-1 receptor-associated kinase 3 IL-1 receptor-associated kinase M
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q14.3
Summary	This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
Disorder MIM:	604459
Disorder Html:	{Asthma susceptibility 5}, 611064 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_007199.2	NP_009130.2	interleukin-1 receptor-associated kinase 3 isoform a
NM_001142523.2	NP_001135995.1	interleukin-1 receptor-associated kinase 3 isoform b
NM_001142523.1	NP_001135995.1	interleukin-1 receptor-associated kinase 3 isoform b
NM_007199.3	NP_009130.2	interleukin-1 receptor-associated kinase 3 isoform a

Pathways from BioSystems

Homologies

	IRAK3	XP_001117080.1
Bos taurus (cattle)	IRAK3	NP_001177228.1
Danio rerio (zebrafish)	irak3	XP_003198307.2
Homo sapiens (human)	IRAK3	NP_009130.2
Canis lupus familiaris (dog)	IRAK3	XP_005625714.1
Mus musculus (house mouse)	Irak3	NP_082955.2
Rattus norvegicus (Norway rat)	Irak3	NP_001101571.1
Pan troglodytes (chimpanzee)	IRAK3	XP_522458.2

Gene Ontology
Bibliography

Related articles in PubMed

Middle east respiratory syndrome corona virus spike glycoprotein suppresses macrophage responses via DPP4-mediated induction of IRAK-M and PPAR?.
Al-Qahtani AA, Lyroni K, Aznaourova M, Tseliou M, Al-Anazi MR, Al-Ahdal MN, Alkahtani S, Sourvinos G, Tsatsanis C
Oncotarget8(6)9053-9066(2017 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

IRAK-M functions to modulate inflammatory signaling pathways and is critical in maintaining immune system homeostasis in the gut. However, increased IRAK-M is associated with increased disease pathogenesis and increased cancer severity in human patients.
Title: Enhanced Mucosal Defense and Reduced Tumor Burden in Mice with the Compromised Negative Regulator IRAK-M.

Data indicate a strong positive correlation between interleukin-1 receptor-associated kinase 3 (IRAK-M) and pSTAT3 protein in colorectal cancer (CRC).
Title: IRAK-M Expression in Tumor Cells Supports Colorectal Cancer Progression through Reduction of Antimicrobial Defense and Stabilization of STAT3.

IRAK3 methylation was associated with tumor stage and poor prognosis of hepatocellular carcinoma patients.
Title: Methylation of IRAK3 is a novel prognostic marker in hepatocellular carcinoma.

HIF1alpha is a regulator of monocyte functional re-programming in sepsis via regulating IRAKM expression.
Title: Human monocytes undergo functional re-programming during sepsis mediated by hypoxia-inducible factor-1?.

Alpha-Melanocyte-Stimulating Hormone Suppresses TLR2-Mediated Functional Responses through IRAK-M in Normal Human Keratinocytes
Title: The Alpha-Melanocyte-Stimulating Hormone Suppresses TLR2-Mediated Functional Responses through IRAK-M in Normal Human Keratinocytes.

The following IRAK3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IRAK3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18753	NM_007199.3 Latest version!	Homo sapiens interleukin 1 receptor associated kinase 3 (IRAK3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu17583	NM_001142523.2 Latest version!	Homo sapiens interleukin 1 receptor associated kinase 3 (IRAK3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$314.30 $449.00
View Old Accession Versions >>
OHu17583	NM_001142523.1	Homo sapiens interleukin 1 receptor associated kinase 3 (IRAK3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$314.30 $449.00
OHu18753	NM_007199.2	Homo sapiens interleukin 1 receptor associated kinase 3 (IRAK3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IRAK3 ( NM_007199.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_009130.2 Homo sapiens interleukin 1 receptor associated kinase 3 (IRAK3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18753
Clone ID Related Accession (Same CDS sequence)	NM_007199.2 , NM_007199.3
Accession Version	NM_007199.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1791bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	interleukin-1 receptor-associated kinase 3 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA594800.1, BC057800.1, BP292474.1, AF113136.1, AC078889.20 and AL049435.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_007199.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.25922.1, SRR1803613.87331.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000261233.9/ ENSP00000261233.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGGA ACTGTGGGGC CCGCGGCGCG CTGTCGGCGC ACACGCTGCT GTTCGACCTG 
CCGCCCGCGC TGCTCGGAGA GCTCTGCGCT GTTCTGGACA GCTGCGACGG CGCGCTGGGC 
TGGCGCGGCC TGGCAGAGAG ACTTTCAAGC AGCTGGCTGG ATGTTCGTCA TATTGAAAAG 
TATGTAGACC AAGGTAAAAG TGGAACAAGA GAATTACTTT GGTCCTGGGC ACAGAAAAAC 
AAGACCATCG GTGACCTTTT ACAGGTCCTC CAGGAGATGG GACATCGTCG AGCTATTCAT 
TTAATTACAA ACTATGGAGC AGTGTTGAGT CCTTCAGAGA AGAGTTATCA GGAAGGTGGA 
TTTCCAAATA TATTATTCAA GGAAACAGCC AATGTCACCG TGGATAATGT TCTTATTCCT 
GAACATAATG AAAAAGGAAT ACTGCTTAAA TCTTCCATCA GCTTTCAAAA TATCATAGAA 
GGAACTAGAA ATTTCCACAA AGACTTCCTA ATTGGAGAAG GAGAGATTTT TGAGGTATAC 
AGAGTGGAGA TTCAAAACCT AACATATGCT GTCAAATTAT TTAAACAGGA GAAAAAAATG 
CAGTGTAAGA AGCATTGGAA GAGGTTTTTA TCTGAGCTTG AAGTTTTACT ACTGTTTCAT 
CACCCAAACA TACTAGAGTT GGCTGCATAT TTTACAGAGA CTGAGAAGTT CTGTCTGATT 
TATCCATACA TGAGAAATGG AACACTTTTT GACAGATTGC AGTGTGTAGG TGACACGGCC 
CCACTCCCTT GGCACATTCG AATCGGTATA TTAATAGGAA TATCCAAAGC CATTCACTAC 
CTGCACAACG TTCAACCATG CTCGGTCATC TGTGGCAGTA TATCAAGTGC AAACATCCTT 
TTGGATGATC AGTTTCAACC CAAACTAACT GATTTTGCCA TGGCACACTT CCGGTCCCAC 
CTAGAACATC AGAGTTGTAC CATAAATATG ACCAGCAGCA GCAGTAAACA TCTGTGGTAC 
ATGCCAGAAG AGTACATCAG ACAGGGGAAA CTTTCCATTA AAACAGATGT CTACAGCTTT 
GGAATTGTAA TAATGGAAGT TCTAACAGGA TGTAGAGTAG TGTTAGATGA TCCAAAACAT 
ATCCAGCTGC GGGATCTCCT TAGAGAATTG ATGGAGAAGA GAGGCCTGGA TTCATGTCTC 
TCATTTCTAG ATAAGAAAGT GCCTCCCTGC CCTCGGAATT TCTCTGCCAA GCTCTTCTGT 
TTGGCAGGCC GGTGTGCTGC AACGCGGGCA AAGTTAAGAC CATCAATGGA TGAAGTTTTA 
AATACTCTTG AAAGTACTCA AGCCAGCTTG TATTTTGCTG AAGATCCTCC CACATCACTA 
AAGTCCTTCA GGTGTCCTTC TCCTCTATTC CTGGAGAATG TACCAAGTAT TCCAGTGGAA 
GATGATGAAA GCCAGAATAA CAATTTACTA CCTTCTGATG AAGGCCTGAG GATAGACAGA 
ATGACTCAGA AAACTCCTTT TGAATGCAGC CAGTCTGAGG TTATGTTTCT GAGCTTGGAC 
AAAAAGCCAG AGAGCAAGAG AAATGAGGAA GCTTGCAACA TGCCCAGTTC TTCTTGTGAA 
GAAAGTTGGT TCCCAAAGTA TATAGTTCCA TCCCAGGACT TAAGGCCCTA TAAGGTAAAT 
ATAGATCCTT CTTCAGAAGC TCCAGGGCAT TCTTGCAGGA GCAGGCCAGT GGAGAGCAGC 
TGTTCCTCCA AATTTTCCTG GGATGAATAT GAACAGTACA AAAAAGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009130.2
CDS	87..1877
Translation	MAGNCGARGALSAHTLLFDLPPALLGELCAVLDSCDGALGWRGLAERLSSSWLDVRHIEKYVDQGKSGTRELLWSWAQKNKTIGDLLQVLQEMGHRRAIHLITNYGAVLSPSEKSYQEGGFPNILFKETANVTVDNVLIPEHNEKGILLKSSISFQNIIEGTRNFHKDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESSCSSKFSWDEYEQYKKE

Target ORF information:

RefSeq Version	NM_007199.3
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin 1 receptor associated kinase 3 (IRAK3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007199.3

ORF Insert Sequence:

ATGGCGGGGA ACTGTGGGGC CCGCGGCGCG CTGTCGGCGC ACACGCTGCT GTTCGACCTG 
CCGCCCGCGC TGCTCGGAGA GCTCTGCGCT GTTCTGGACA GCTGCGACGG CGCGCTGGGC 
TGGCGCGGCC TGGCAGAGAG ACTTTCAAGC AGCTGGCTGG ATGTTCGTCA TATTGAAAAG 
TATGTAGACC AAGGTAAAAG TGGAACAAGA GAATTACTTT GGTCCTGGGC ACAGAAAAAC 
AAGACCATCG GTGACCTTTT ACAGGTCCTC CAGGAGATGG GACATCGTCG AGCTATTCAT 
TTAATTACAA ACTATGGAGC AGTGTTGAGT CCTTCAGAGA AGAGTTATCA GGAAGGTGGA 
TTTCCAAATA TATTATTCAA GGAAACAGCC AATGTCACCG TGGATAATGT TCTTATTCCT 
GAACATAATG AAAAAGGAAT ACTGCTTAAA TCTTCCATCA GCTTTCAAAA TATCATAGAA 
GGAACTAGAA ATTTCCACAA AGACTTCCTA ATTGGAGAAG GAGAGATTTT TGAGGTATAC 
AGAGTGGAGA TTCAAAACCT AACATATGCT GTCAAATTAT TTAAACAGGA GAAAAAAATG 
CAGTGTAAGA AGCATTGGAA GAGGTTTTTA TCTGAGCTTG AAGTTTTACT ACTGTTTCAT 
CACCCAAACA TACTAGAGTT GGCTGCATAT TTTACAGAGA CTGAGAAGTT CTGTCTGATT 
TATCCATACA TGAGAAATGG AACACTTTTT GACAGATTGC AGTGTGTAGG TGACACGGCC 
CCACTCCCTT GGCACATTCG AATCGGTATA TTAATAGGAA TATCCAAAGC CATTCACTAC 
CTGCACAACG TTCAACCATG CTCGGTCATC TGTGGCAGTA TATCAAGTGC AAACATCCTT 
TTGGATGATC AGTTTCAACC CAAACTAACT GATTTTGCCA TGGCACACTT CCGGTCCCAC 
CTAGAACATC AGAGTTGTAC CATAAATATG ACCAGCAGCA GCAGTAAACA TCTGTGGTAC 
ATGCCAGAAG AGTACATCAG ACAGGGGAAA CTTTCCATTA AAACAGATGT CTACAGCTTT 
GGAATTGTAA TAATGGAAGT TCTAACAGGA TGTAGAGTAG TGTTAGATGA TCCAAAACAT 
ATCCAGCTGC GGGATCTCCT TAGAGAATTG ATGGAGAAGA GAGGCCTGGA TTCATGTCTC 
TCATTTCTAG ATAAGAAAGT GCCTCCCTGC CCTCGGAATT TCTCTGCCAA GCTCTTCTGT 
TTGGCAGGCC GGTGTGCTGC AACGCGGGCA AAGTTAAGAC CATCAATGGA TGAAGTTTTA 
AATACTCTTG AAAGTACTCA AGCCAGCTTG TATTTTGCTG AAGATCCTCC CACATCACTA 
AAGTCCTTCA GGTGTCCTTC TCCTCTATTC CTGGAGAATG TACCAAGTAT TCCAGTGGAA 
GATGATGAAA GCCAGAATAA CAATTTACTA CCTTCTGATG AAGGCCTGAG GATAGACAGA 
ATGACTCAGA AAACTCCTTT TGAATGCAGC CAGTCTGAGG TTATGTTTCT GAGCTTGGAC 
AAAAAGCCAG AGAGCAAGAG AAATGAGGAA GCTTGCAACA TGCCCAGTTC TTCTTGTGAA 
GAAAGTTGGT TCCCAAAGTA TATAGTTCCA TCCCAGGACT TAAGGCCCTA TAAGGTAAAT 
ATAGATCCTT CTTCAGAAGC TCCAGGGCAT TCTTGCAGGA GCAGGCCAGT GGAGAGCAGC 
TGTTCCTCCA AATTTTCCTG GGATGAATAT GAACAGTACA AAAAAGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRAK3 ( NM_001142523.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001135995.1 Homo sapiens interleukin 1 receptor associated kinase 3 (IRAK3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17583
Clone ID Related Accession (Same CDS sequence)	NM_001142523.2 , NM_001142523.1
Accession Version	NM_001142523.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1608bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Homo sapiens(human)
Product	interleukin-1 receptor-associated kinase 3 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078927.20, AK298645.1, BP292474.1, BQ009433.1, AC078889.20 and AL049435.1. On May 31, 2019 this sequence version replaced NM_001142523.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform b), compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.43078.1, SRR1803616.57266.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGGA ACTGTGGGGC CCGCGGCGCG CTGTCGGCGC ACACGCTGCT GTTCGACCTG 
CCGCCCGCGC TGCTCGGAGA GCTCTGCGCT GTTCTGGACA GCTGCGACGG CGCGCTGGGC 
TGGCGCGGCC TGGGAGCAGT GTTGAGTCCT TCAGAGAAGA GTTATCAGGA AGGTGGATTT 
CCAAATATAT TATTCAAGGA AACAGCCAAT GTCACCGTGG ATAATGTTCT TATTCCTGAA 
CATAATGAAA AAGGAATACT GCTTAAATCT TCCATCAGCT TTCAAAATAT CATAGAAGGA 
ACTAGAAATT TCCACAAAGA CTTCCTAATT GGAGAAGGAG AGATTTTTGA GGTATACAGA 
GTGGAGATTC AAAACCTAAC ATATGCTGTC AAATTATTTA AACAGGAGAA AAAAATGCAG 
TGTAAGAAGC ATTGGAAGAG GTTTTTATCT GAGCTTGAAG TTTTACTACT GTTTCATCAC 
CCAAACATAC TAGAGTTGGC TGCATATTTT ACAGAGACTG AGAAGTTCTG TCTGATTTAT 
CCATACATGA GAAATGGAAC ACTTTTTGAC AGATTGCAGT GTGTAGGTGA CACGGCCCCA 
CTCCCTTGGC ACATTCGAAT CGGTATATTA ATAGGAATAT CCAAAGCCAT TCACTACCTG 
CACAACGTTC AACCATGCTC GGTCATCTGT GGCAGTATAT CAAGTGCAAA CATCCTTTTG 
GATGATCAGT TTCAACCCAA ACTAACTGAT TTTGCCATGG CACACTTCCG GTCCCACCTA 
GAACATCAGA GTTGTACCAT AAATATGACC AGCAGCAGCA GTAAACATCT GTGGTACATG 
CCAGAAGAGT ACATCAGACA GGGGAAACTT TCCATTAAAA CAGATGTCTA CAGCTTTGGA 
ATTGTAATAA TGGAAGTTCT AACAGGATGT AGAGTAGTGT TAGATGATCC AAAACATATC 
CAGCTGCGGG ATCTCCTTAG AGAATTGATG GAGAAGAGAG GCCTGGATTC ATGTCTCTCA 
TTTCTAGATA AGAAAGTGCC TCCCTGCCCT CGGAATTTCT CTGCCAAGCT CTTCTGTTTG 
GCAGGCCGGT GTGCTGCAAC GCGGGCAAAG TTAAGACCAT CAATGGATGA AGTTTTAAAT 
ACTCTTGAAA GTACTCAAGC CAGCTTGTAT TTTGCTGAAG ATCCTCCCAC ATCACTAAAG 
TCCTTCAGGT GTCCTTCTCC TCTATTCCTG GAGAATGTAC CAAGTATTCC AGTGGAAGAT 
GATGAAAGCC AGAATAACAA TTTACTACCT TCTGATGAAG GCCTGAGGAT AGACAGAATG 
ACTCAGAAAA CTCCTTTTGA ATGCAGCCAG TCTGAGGTTA TGTTTCTGAG CTTGGACAAA 
AAGCCAGAGA GCAAGAGAAA TGAGGAAGCT TGCAACATGC CCAGTTCTTC TTGTGAAGAA 
AGTTGGTTCC CAAAGTATAT AGTTCCATCC CAGGACTTAA GGCCCTATAA GGTAAATATA 
GATCCTTCTT CAGAAGCTCC AGGGCATTCT TGCAGGAGCA GGCCAGTGGA GAGCAGCTGT 
TCCTCCAAAT TTTCCTGGGA TGAATATGAA CAGTACAAAA AAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001135995.1
CDS	87..1694
Translation	MAGNCGARGALSAHTLLFDLPPALLGELCAVLDSCDGALGWRGLGAVLSPSEKSYQEGGFPNILFKETANVTVDNVLIPEHNEKGILLKSSISFQNIIEGTRNFHKDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESSCSSKFSWDEYEQYKKE

Target ORF information:

RefSeq Version	NM_001142523.2
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin 1 receptor associated kinase 3 (IRAK3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142523.2

ORF Insert Sequence:

ATGGCGGGGA ACTGTGGGGC CCGCGGCGCG CTGTCGGCGC ACACGCTGCT GTTCGACCTG 
CCGCCCGCGC TGCTCGGAGA GCTCTGCGCT GTTCTGGACA GCTGCGACGG CGCGCTGGGC 
TGGCGCGGCC TGGGAGCAGT GTTGAGTCCT TCAGAGAAGA GTTATCAGGA AGGTGGATTT 
CCAAATATAT TATTCAAGGA AACAGCCAAT GTCACCGTGG ATAATGTTCT TATTCCTGAA 
CATAATGAAA AAGGAATACT GCTTAAATCT TCCATCAGCT TTCAAAATAT CATAGAAGGA 
ACTAGAAATT TCCACAAAGA CTTCCTAATT GGAGAAGGAG AGATTTTTGA GGTATACAGA 
GTGGAGATTC AAAACCTAAC ATATGCTGTC AAATTATTTA AACAGGAGAA AAAAATGCAG 
TGTAAGAAGC ATTGGAAGAG GTTTTTATCT GAGCTTGAAG TTTTACTACT GTTTCATCAC 
CCAAACATAC TAGAGTTGGC TGCATATTTT ACAGAGACTG AGAAGTTCTG TCTGATTTAT 
CCATACATGA GAAATGGAAC ACTTTTTGAC AGATTGCAGT GTGTAGGTGA CACGGCCCCA 
CTCCCTTGGC ACATTCGAAT CGGTATATTA ATAGGAATAT CCAAAGCCAT TCACTACCTG 
CACAACGTTC AACCATGCTC GGTCATCTGT GGCAGTATAT CAAGTGCAAA CATCCTTTTG 
GATGATCAGT TTCAACCCAA ACTAACTGAT TTTGCCATGG CACACTTCCG GTCCCACCTA 
GAACATCAGA GTTGTACCAT AAATATGACC AGCAGCAGCA GTAAACATCT GTGGTACATG 
CCAGAAGAGT ACATCAGACA GGGGAAACTT TCCATTAAAA CAGATGTCTA CAGCTTTGGA 
ATTGTAATAA TGGAAGTTCT AACAGGATGT AGAGTAGTGT TAGATGATCC AAAACATATC 
CAGCTGCGGG ATCTCCTTAG AGAATTGATG GAGAAGAGAG GCCTGGATTC ATGTCTCTCA 
TTTCTAGATA AGAAAGTGCC TCCCTGCCCT CGGAATTTCT CTGCCAAGCT CTTCTGTTTG 
GCAGGCCGGT GTGCTGCAAC GCGGGCAAAG TTAAGACCAT CAATGGATGA AGTTTTAAAT 
ACTCTTGAAA GTACTCAAGC CAGCTTGTAT TTTGCTGAAG ATCCTCCCAC ATCACTAAAG 
TCCTTCAGGT GTCCTTCTCC TCTATTCCTG GAGAATGTAC CAAGTATTCC AGTGGAAGAT 
GATGAAAGCC AGAATAACAA TTTACTACCT TCTGATGAAG GCCTGAGGAT AGACAGAATG 
ACTCAGAAAA CTCCTTTTGA ATGCAGCCAG TCTGAGGTTA TGTTTCTGAG CTTGGACAAA 
AAGCCAGAGA GCAAGAGAAA TGAGGAAGCT TGCAACATGC CCAGTTCTTC TTGTGAAGAA 
AGTTGGTTCC CAAAGTATAT AGTTCCATCC CAGGACTTAA GGCCCTATAA GGTAAATATA 
GATCCTTCTT CAGAAGCTCC AGGGCATTCT TGCAGGAGCA GGCCAGTGGA GAGCAGCTGT 
TCCTCCAAAT TTTCCTGGGA TGAATATGAA CAGTACAAAA AAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRAK3 ( NM_001142523.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001135995.1 Homo sapiens interleukin 1 receptor associated kinase 3 (IRAK3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17583
Clone ID Related Accession (Same CDS sequence)	NM_001142523.2 , NM_001142523.1
Accession Version	NM_001142523.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1608bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	interleukin-1 receptor-associated kinase 3 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078927.20, AK298645.1, BP292474.1, BQ009433.1, AC078889.20 and AL049435.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform b), compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.43078.1, SRR1803616.57266.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGGA ACTGTGGGGC CCGCGGCGCG CTGTCGGCGC ACACGCTGCT GTTCGACCTG 
CCGCCCGCGC TGCTCGGAGA GCTCTGCGCT GTTCTGGACA GCTGCGACGG CGCGCTGGGC 
TGGCGCGGCC TGGGAGCAGT GTTGAGTCCT TCAGAGAAGA GTTATCAGGA AGGTGGATTT 
CCAAATATAT TATTCAAGGA AACAGCCAAT GTCACCGTGG ATAATGTTCT TATTCCTGAA 
CATAATGAAA AAGGAATACT GCTTAAATCT TCCATCAGCT TTCAAAATAT CATAGAAGGA 
ACTAGAAATT TCCACAAAGA CTTCCTAATT GGAGAAGGAG AGATTTTTGA GGTATACAGA 
GTGGAGATTC AAAACCTAAC ATATGCTGTC AAATTATTTA AACAGGAGAA AAAAATGCAG 
TGTAAGAAGC ATTGGAAGAG GTTTTTATCT GAGCTTGAAG TTTTACTACT GTTTCATCAC 
CCAAACATAC TAGAGTTGGC TGCATATTTT ACAGAGACTG AGAAGTTCTG TCTGATTTAT 
CCATACATGA GAAATGGAAC ACTTTTTGAC AGATTGCAGT GTGTAGGTGA CACGGCCCCA 
CTCCCTTGGC ACATTCGAAT CGGTATATTA ATAGGAATAT CCAAAGCCAT TCACTACCTG 
CACAACGTTC AACCATGCTC GGTCATCTGT GGCAGTATAT CAAGTGCAAA CATCCTTTTG 
GATGATCAGT TTCAACCCAA ACTAACTGAT TTTGCCATGG CACACTTCCG GTCCCACCTA 
GAACATCAGA GTTGTACCAT AAATATGACC AGCAGCAGCA GTAAACATCT GTGGTACATG 
CCAGAAGAGT ACATCAGACA GGGGAAACTT TCCATTAAAA CAGATGTCTA CAGCTTTGGA 
ATTGTAATAA TGGAAGTTCT AACAGGATGT AGAGTAGTGT TAGATGATCC AAAACATATC 
CAGCTGCGGG ATCTCCTTAG AGAATTGATG GAGAAGAGAG GCCTGGATTC ATGTCTCTCA 
TTTCTAGATA AGAAAGTGCC TCCCTGCCCT CGGAATTTCT CTGCCAAGCT CTTCTGTTTG 
GCAGGCCGGT GTGCTGCAAC GCGGGCAAAG TTAAGACCAT CAATGGATGA AGTTTTAAAT 
ACTCTTGAAA GTACTCAAGC CAGCTTGTAT TTTGCTGAAG ATCCTCCCAC ATCACTAAAG 
TCCTTCAGGT GTCCTTCTCC TCTATTCCTG GAGAATGTAC CAAGTATTCC AGTGGAAGAT 
GATGAAAGCC AGAATAACAA TTTACTACCT TCTGATGAAG GCCTGAGGAT AGACAGAATG 
ACTCAGAAAA CTCCTTTTGA ATGCAGCCAG TCTGAGGTTA TGTTTCTGAG CTTGGACAAA 
AAGCCAGAGA GCAAGAGAAA TGAGGAAGCT TGCAACATGC CCAGTTCTTC TTGTGAAGAA 
AGTTGGTTCC CAAAGTATAT AGTTCCATCC CAGGACTTAA GGCCCTATAA GGTAAATATA 
GATCCTTCTT CAGAAGCTCC AGGGCATTCT TGCAGGAGCA GGCCAGTGGA GAGCAGCTGT 
TCCTCCAAAT TTTCCTGGGA TGAATATGAA CAGTACAAAA AAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001135995.1
CDS	103..1710
Translation	MAGNCGARGALSAHTLLFDLPPALLGELCAVLDSCDGALGWRGLGAVLSPSEKSYQEGGFPNILFKETANVTVDNVLIPEHNEKGILLKSSISFQNIIEGTRNFHKDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESSCSSKFSWDEYEQYKKE

Target ORF information:

RefSeq Version	NM_001142523.1
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin 1 receptor associated kinase 3 (IRAK3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142523.1

ORF Insert Sequence:

ATGGCGGGGA ACTGTGGGGC CCGCGGCGCG CTGTCGGCGC ACACGCTGCT GTTCGACCTG 
CCGCCCGCGC TGCTCGGAGA GCTCTGCGCT GTTCTGGACA GCTGCGACGG CGCGCTGGGC 
TGGCGCGGCC TGGGAGCAGT GTTGAGTCCT TCAGAGAAGA GTTATCAGGA AGGTGGATTT 
CCAAATATAT TATTCAAGGA AACAGCCAAT GTCACCGTGG ATAATGTTCT TATTCCTGAA 
CATAATGAAA AAGGAATACT GCTTAAATCT TCCATCAGCT TTCAAAATAT CATAGAAGGA 
ACTAGAAATT TCCACAAAGA CTTCCTAATT GGAGAAGGAG AGATTTTTGA GGTATACAGA 
GTGGAGATTC AAAACCTAAC ATATGCTGTC AAATTATTTA AACAGGAGAA AAAAATGCAG 
TGTAAGAAGC ATTGGAAGAG GTTTTTATCT GAGCTTGAAG TTTTACTACT GTTTCATCAC 
CCAAACATAC TAGAGTTGGC TGCATATTTT ACAGAGACTG AGAAGTTCTG TCTGATTTAT 
CCATACATGA GAAATGGAAC ACTTTTTGAC AGATTGCAGT GTGTAGGTGA CACGGCCCCA 
CTCCCTTGGC ACATTCGAAT CGGTATATTA ATAGGAATAT CCAAAGCCAT TCACTACCTG 
CACAACGTTC AACCATGCTC GGTCATCTGT GGCAGTATAT CAAGTGCAAA CATCCTTTTG 
GATGATCAGT TTCAACCCAA ACTAACTGAT TTTGCCATGG CACACTTCCG GTCCCACCTA 
GAACATCAGA GTTGTACCAT AAATATGACC AGCAGCAGCA GTAAACATCT GTGGTACATG 
CCAGAAGAGT ACATCAGACA GGGGAAACTT TCCATTAAAA CAGATGTCTA CAGCTTTGGA 
ATTGTAATAA TGGAAGTTCT AACAGGATGT AGAGTAGTGT TAGATGATCC AAAACATATC 
CAGCTGCGGG ATCTCCTTAG AGAATTGATG GAGAAGAGAG GCCTGGATTC ATGTCTCTCA 
TTTCTAGATA AGAAAGTGCC TCCCTGCCCT CGGAATTTCT CTGCCAAGCT CTTCTGTTTG 
GCAGGCCGGT GTGCTGCAAC GCGGGCAAAG TTAAGACCAT CAATGGATGA AGTTTTAAAT 
ACTCTTGAAA GTACTCAAGC CAGCTTGTAT TTTGCTGAAG ATCCTCCCAC ATCACTAAAG 
TCCTTCAGGT GTCCTTCTCC TCTATTCCTG GAGAATGTAC CAAGTATTCC AGTGGAAGAT 
GATGAAAGCC AGAATAACAA TTTACTACCT TCTGATGAAG GCCTGAGGAT AGACAGAATG 
ACTCAGAAAA CTCCTTTTGA ATGCAGCCAG TCTGAGGTTA TGTTTCTGAG CTTGGACAAA 
AAGCCAGAGA GCAAGAGAAA TGAGGAAGCT TGCAACATGC CCAGTTCTTC TTGTGAAGAA 
AGTTGGTTCC CAAAGTATAT AGTTCCATCC CAGGACTTAA GGCCCTATAA GGTAAATATA 
GATCCTTCTT CAGAAGCTCC AGGGCATTCT TGCAGGAGCA GGCCAGTGGA GAGCAGCTGT 
TCCTCCAAAT TTTCCTGGGA TGAATATGAA CAGTACAAAA AAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRAK3 ( NM_007199.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_009130.2 Homo sapiens interleukin 1 receptor associated kinase 3 (IRAK3), transcript variant 1, mRNA.

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CloneID	OHu18753
Clone ID Related Accession (Same CDS sequence)	NM_007199.2 , NM_007199.3
Accession Version	NM_007199.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1791bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Homo sapiens(human)
Product	interleukin-1 receptor-associated kinase 3 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA594800.1, BC057800.1, BP292474.1, AF113136.1, AC078889.20 and AL049435.1. This sequence is a reference standard in the RefSeqGene project. On Dec 9, 2008 this sequence version replaced NM_007199.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.25922.1, SRR1803613.87331.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGGA ACTGTGGGGC CCGCGGCGCG CTGTCGGCGC ACACGCTGCT GTTCGACCTG 
CCGCCCGCGC TGCTCGGAGA GCTCTGCGCT GTTCTGGACA GCTGCGACGG CGCGCTGGGC 
TGGCGCGGCC TGGCAGAGAG ACTTTCAAGC AGCTGGCTGG ATGTTCGTCA TATTGAAAAG 
TATGTAGACC AAGGTAAAAG TGGAACAAGA GAATTACTTT GGTCCTGGGC ACAGAAAAAC 
AAGACCATCG GTGACCTTTT ACAGGTCCTC CAGGAGATGG GACATCGTCG AGCTATTCAT 
TTAATTACAA ACTATGGAGC AGTGTTGAGT CCTTCAGAGA AGAGTTATCA GGAAGGTGGA 
TTTCCAAATA TATTATTCAA GGAAACAGCC AATGTCACCG TGGATAATGT TCTTATTCCT 
GAACATAATG AAAAAGGAAT ACTGCTTAAA TCTTCCATCA GCTTTCAAAA TATCATAGAA 
GGAACTAGAA ATTTCCACAA AGACTTCCTA ATTGGAGAAG GAGAGATTTT TGAGGTATAC 
AGAGTGGAGA TTCAAAACCT AACATATGCT GTCAAATTAT TTAAACAGGA GAAAAAAATG 
CAGTGTAAGA AGCATTGGAA GAGGTTTTTA TCTGAGCTTG AAGTTTTACT ACTGTTTCAT 
CACCCAAACA TACTAGAGTT GGCTGCATAT TTTACAGAGA CTGAGAAGTT CTGTCTGATT 
TATCCATACA TGAGAAATGG AACACTTTTT GACAGATTGC AGTGTGTAGG TGACACGGCC 
CCACTCCCTT GGCACATTCG AATCGGTATA TTAATAGGAA TATCCAAAGC CATTCACTAC 
CTGCACAACG TTCAACCATG CTCGGTCATC TGTGGCAGTA TATCAAGTGC AAACATCCTT 
TTGGATGATC AGTTTCAACC CAAACTAACT GATTTTGCCA TGGCACACTT CCGGTCCCAC 
CTAGAACATC AGAGTTGTAC CATAAATATG ACCAGCAGCA GCAGTAAACA TCTGTGGTAC 
ATGCCAGAAG AGTACATCAG ACAGGGGAAA CTTTCCATTA AAACAGATGT CTACAGCTTT 
GGAATTGTAA TAATGGAAGT TCTAACAGGA TGTAGAGTAG TGTTAGATGA TCCAAAACAT 
ATCCAGCTGC GGGATCTCCT TAGAGAATTG ATGGAGAAGA GAGGCCTGGA TTCATGTCTC 
TCATTTCTAG ATAAGAAAGT GCCTCCCTGC CCTCGGAATT TCTCTGCCAA GCTCTTCTGT 
TTGGCAGGCC GGTGTGCTGC AACGCGGGCA AAGTTAAGAC CATCAATGGA TGAAGTTTTA 
AATACTCTTG AAAGTACTCA AGCCAGCTTG TATTTTGCTG AAGATCCTCC CACATCACTA 
AAGTCCTTCA GGTGTCCTTC TCCTCTATTC CTGGAGAATG TACCAAGTAT TCCAGTGGAA 
GATGATGAAA GCCAGAATAA CAATTTACTA CCTTCTGATG AAGGCCTGAG GATAGACAGA 
ATGACTCAGA AAACTCCTTT TGAATGCAGC CAGTCTGAGG TTATGTTTCT GAGCTTGGAC 
AAAAAGCCAG AGAGCAAGAG AAATGAGGAA GCTTGCAACA TGCCCAGTTC TTCTTGTGAA 
GAAAGTTGGT TCCCAAAGTA TATAGTTCCA TCCCAGGACT TAAGGCCCTA TAAGGTAAAT 
ATAGATCCTT CTTCAGAAGC TCCAGGGCAT TCTTGCAGGA GCAGGCCAGT GGAGAGCAGC 
TGTTCCTCCA AATTTTCCTG GGATGAATAT GAACAGTACA AAAAAGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009130.2
CDS	103..1893
Translation	MAGNCGARGALSAHTLLFDLPPALLGELCAVLDSCDGALGWRGLAERLSSSWLDVRHIEKYVDQGKSGTRELLWSWAQKNKTIGDLLQVLQEMGHRRAIHLITNYGAVLSPSEKSYQEGGFPNILFKETANVTVDNVLIPEHNEKGILLKSSISFQNIIEGTRNFHKDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESSCSSKFSWDEYEQYKKE

Target ORF information:

RefSeq Version	NM_007199.2
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin 1 receptor associated kinase 3 (IRAK3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007199.2

ORF Insert Sequence:

ATGGCGGGGA ACTGTGGGGC CCGCGGCGCG CTGTCGGCGC ACACGCTGCT GTTCGACCTG 
CCGCCCGCGC TGCTCGGAGA GCTCTGCGCT GTTCTGGACA GCTGCGACGG CGCGCTGGGC 
TGGCGCGGCC TGGCAGAGAG ACTTTCAAGC AGCTGGCTGG ATGTTCGTCA TATTGAAAAG 
TATGTAGACC AAGGTAAAAG TGGAACAAGA GAATTACTTT GGTCCTGGGC ACAGAAAAAC 
AAGACCATCG GTGACCTTTT ACAGGTCCTC CAGGAGATGG GACATCGTCG AGCTATTCAT 
TTAATTACAA ACTATGGAGC AGTGTTGAGT CCTTCAGAGA AGAGTTATCA GGAAGGTGGA 
TTTCCAAATA TATTATTCAA GGAAACAGCC AATGTCACCG TGGATAATGT TCTTATTCCT 
GAACATAATG AAAAAGGAAT ACTGCTTAAA TCTTCCATCA GCTTTCAAAA TATCATAGAA 
GGAACTAGAA ATTTCCACAA AGACTTCCTA ATTGGAGAAG GAGAGATTTT TGAGGTATAC 
AGAGTGGAGA TTCAAAACCT AACATATGCT GTCAAATTAT TTAAACAGGA GAAAAAAATG 
CAGTGTAAGA AGCATTGGAA GAGGTTTTTA TCTGAGCTTG AAGTTTTACT ACTGTTTCAT 
CACCCAAACA TACTAGAGTT GGCTGCATAT TTTACAGAGA CTGAGAAGTT CTGTCTGATT 
TATCCATACA TGAGAAATGG AACACTTTTT GACAGATTGC AGTGTGTAGG TGACACGGCC 
CCACTCCCTT GGCACATTCG AATCGGTATA TTAATAGGAA TATCCAAAGC CATTCACTAC 
CTGCACAACG TTCAACCATG CTCGGTCATC TGTGGCAGTA TATCAAGTGC AAACATCCTT 
TTGGATGATC AGTTTCAACC CAAACTAACT GATTTTGCCA TGGCACACTT CCGGTCCCAC 
CTAGAACATC AGAGTTGTAC CATAAATATG ACCAGCAGCA GCAGTAAACA TCTGTGGTAC 
ATGCCAGAAG AGTACATCAG ACAGGGGAAA CTTTCCATTA AAACAGATGT CTACAGCTTT 
GGAATTGTAA TAATGGAAGT TCTAACAGGA TGTAGAGTAG TGTTAGATGA TCCAAAACAT 
ATCCAGCTGC GGGATCTCCT TAGAGAATTG ATGGAGAAGA GAGGCCTGGA TTCATGTCTC 
TCATTTCTAG ATAAGAAAGT GCCTCCCTGC CCTCGGAATT TCTCTGCCAA GCTCTTCTGT 
TTGGCAGGCC GGTGTGCTGC AACGCGGGCA AAGTTAAGAC CATCAATGGA TGAAGTTTTA 
AATACTCTTG AAAGTACTCA AGCCAGCTTG TATTTTGCTG AAGATCCTCC CACATCACTA 
AAGTCCTTCA GGTGTCCTTC TCCTCTATTC CTGGAGAATG TACCAAGTAT TCCAGTGGAA 
GATGATGAAA GCCAGAATAA CAATTTACTA CCTTCTGATG AAGGCCTGAG GATAGACAGA 
ATGACTCAGA AAACTCCTTT TGAATGCAGC CAGTCTGAGG TTATGTTTCT GAGCTTGGAC 
AAAAAGCCAG AGAGCAAGAG AAATGAGGAA GCTTGCAACA TGCCCAGTTC TTCTTGTGAA 
GAAAGTTGGT TCCCAAAGTA TATAGTTCCA TCCCAGGACT TAAGGCCCTA TAAGGTAAAT 
ATAGATCCTT CTTCAGAAGC TCCAGGGCAT TCTTGCAGGA GCAGGCCAGT GGAGAGCAGC 
TGTTCCTCCA AATTTTCCTG GGATGAATAT GAACAGTACA AAAAAGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Middle east respiratory syndrome corona virus spike glycoprotein suppresses macrophage responses via DPP4-mediated induction of IRAK-M and PPAR?.
Oncotarget8(6)9053-9066(2017 Feb)
Al-Qahtani AA,Lyroni K,Aznaourova M,Tseliou M,Al-Anazi MR,Al-Ahdal MN,Alkahtani S,Sourvinos G,Tsatsanis C

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IRAK3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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