SPINK5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SPINK5
Entrez Gene ID	11005
Full Name	serine peptidase inhibitor, Kazal type 5
Synonyms	LEKTI,LETKI,NETS,NS,VAKTI
General protein information	Preferred Names serine peptidase inhibitor, Kazal type 5 Names serine protease inhibitor Kazal-type 5 lympho-epithelial Kazal-type-related inhibitor lymphoepithelial Kazal-type-related inhibitor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q32
Summary	This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015].
Disorder MIM:	605010
Disorder Html:	Netherton syndrome, 256500 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_006846.3	NP_006837.2	serine protease inhibitor Kazal-type 5 isoform b preproprotein
NM_001127698.1	NP_001121170.1	serine protease inhibitor Kazal-type 5 isoform a preproprotein
NM_001127698.2	NP_001121170.1	serine protease inhibitor Kazal-type 5 isoform a preproprotein
NM_001127699.1	NP_001121171.1	serine protease inhibitor Kazal-type 5 isoform c preproprotein
NM_001127699.2	NP_001121171.1	serine protease inhibitor Kazal-type 5 isoform c preproprotein
NM_006846.4	NP_006837.2	serine protease inhibitor Kazal-type 5 isoform b preproprotein
XM_011537551.2	XP_011535853.1	serine protease inhibitor Kazal-type 5 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SPINK5	XP_001160618.1
	SPINK5	XP_001103296.1
Rattus norvegicus (Norway rat)	Spink5	NP_001164077.1
Canis lupus familiaris (dog)	SPINK5	NP_001020568.1
Rattus norvegicus (Norway rat)	LOC100910851	XP_003749120.1
Gallus gallus (chicken)	SPINK7	NP_001106132.1
Homo sapiens (human)	SPINK5	NP_001121170.1
Bos taurus (cattle)	SPINK5	NP_001095572.1
Gallus gallus (chicken)	SPINK5	XP_004944964.1
Mus musculus (house mouse)	Spink5	NP_001074649.1

Gene Ontology
Bibliography

Related articles in PubMed

SPINK5 is associated with early-onset and CHI3L1 with late-onset atopic dermatitis.
De?man K, Koro?ec P, Rupnik H, Rijavec M
International journal of immunogenetics44(5)212-218(2017 Oct)

The skin barrier function gene SPINK5 is associated with?challenge-proven IgE-mediated food allergy in infants.
Ashley SE, Tan HT, Vuillermin P, Dharmage SC, Tang MLK, Koplin J, Gurrin LC, Lowe A, Lodge C, Ponsonby AL, Molloy J, Martin P, Matheson MC, Saffery R, Allen KJ, Ellis JA, Martino D, ,
Allergy72(9)1356-1364(2017 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

impaired KLK7 secretion from lamellar granules and increased LEKTI expression could underlie the insufficient activation of KLK in atopic dermatitis.
Title: Incomplete KLK7 Secretion and Upregulated LEKTI Expression Underlie Hyperkeratotic Stratum Corneum in Atopic Dermatitis.

This report discloses a prevalent SPINK5 founder mutation in Finland and illustrates Netherton syndrome phenotype variability
Title: Intrafamily and Interfamilial Phenotype Variation and Immature Immunity in Patients With Netherton Syndrome and Finnish SPINK5 Founder Mutation.

New mutation leading to the full variety of typical features of the Netherton syndrome.
Title: New mutation leading to the full variety of typical features of the Netherton syndrome.

The results suggest that SPINK5 and ADRB2 haplotypes might play a role in the susceptibility to childhood-onset asthma
Title: SPINK5 and ADRB2 haplotypes are risk factors for asthma in Mexican pediatric patients.

The effect of GATA3 on SPINK5 expression was indirect and GATA3 alone was insufficient for final differentiation of keratinocytes where full SPINK5 expression was observed.
Title: Regulation of serine protease inhibitor Kazal type-5 (SPINK5) gene expression in the keratinocytes.

The following SPINK5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SPINK5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31833	NM_001127698.2 Latest version!	Homo sapiens serine peptidase inhibitor Kazal type 5 (SPINK5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu19403	NM_006846.4 Latest version!	Homo sapiens serine peptidase inhibitor Kazal type 5 (SPINK5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OHu31774	NM_001127699.2 Latest version!	Homo sapiens serine peptidase inhibitor Kazal type 5 (SPINK5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00
OHu64572	XM_011537551.2 Latest version!	Homo sapiens serine peptidase inhibitor Kazal type 5 (SPINK5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
View Old Accession Versions >>
OHu31833	NM_001127698.1	Homo sapiens serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
OHu31774	NM_001127699.1	Homo sapiens serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00
OHu19403	NM_006846.3	Homo sapiens serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SPINK5 ( NM_001127698.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001121170.1 Homo sapiens serine peptidase inhibitor Kazal type 5 (SPINK5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu31833
Clone ID Related Accession (Same CDS sequence)	NM_001127698.1 , NM_001127698.2
Accession Version	NM_001127698.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3285bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-01
Organism	Homo sapiens(human)
Product	serine protease inhibitor Kazal-type 5 isoform a preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ149928.1, AK307588.1, AK307648.1, AK025197.1, BI256857.1, AI341060.1, DR421881.1 and AC116334.2. On Jun 2, 2019 this sequence version replaced NM_001127698.1. Transcript Variant: This variant (1, also known as SPINK5l) represents the longest transcript and encodes the longest isoform (a, also known as the LEKTIl or long isoform). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ149928.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAAGATAG CCACAGTGTC AGTGCTTCTG CCCTTGGCTC TTTGCCTCAT ACAAGATGCT 
GCCAGTAAGA ATGAAGATCA GGAAATGTGC CATGAATTTC AGGCATTTAT GAAAAATGGA 
AAACTGTTCT GTCCCCAGGA TAAGAAATTT TTTCAAAGTC TTGATGGAAT AATGTTCATC 
AATAAATGTG CCACGTGCAA AATGATACTG GAAAAAGAAG CAAAATCACA GAAGAGGGCC 
AGGCATTTAG CAAGAGCTCC CAAGGCTACT GCCCCAACAG AGCTGAATTG TGATGATTTT 
AAAAAAGGAG AAAGAGATGG GGATTTTATC TGTCCTGATT ATTATGAAGC TGTTTGTGGC 
ACAGATGGGA AAACATATGA CAACAGATGT GCACTGTGTG CTGAGAATGC GAAAACCGGG 
TCCCAAATTG GTGTAAAAAG TGAAGGGGAA TGTAAGAGCA GTAATCCAGA GCAGGATGTA 
TGCAGTGCTT TTCGGCCCTT TGTTAGAGAT GGAAGACTTG GATGCACAAG GGAAAATGAT 
CCTGTTCTTG GTCCTGATGG GAAGACGCAT GGCAATAAGT GTGCAATGTG TGCTGAGCTG 
TTTTTAAAAG AAGCTGAAAA TGCCAAGCGA GAGGGTGAAA CTAGAATTCG ACGAAATGCT 
GAAAAGGATT TTTGCAAGGA ATATGAAAAA CAAGTGAGAA ATGGAAGGCT TTTTTGTACA 
CGGGAGAGTG ATCCAGTCCG TGGCCCTGAC GGCAGGATGC ATGGCAACAA ATGTGCCCTG 
TGTGCTGAAA TTTTCAAGCA GCGTTTTTCA GAGGAAAACA GTAAAACAGA TCAAAATTTG 
GGAAAAGCTG AAGAAAAAAC TAAAGTTAAA AGAGAAATTG TGAAACTCTG CAGTCAATAT 
CAAAATCAGG CAAAGAATGG AATACTTTTC TGTACCAGAG AAAATGACCC TATTCGTGGT 
CCAGATGGGA AAATGCATGG CAACTTGTGT TCCATGTGTC AAGCCTACTT CCAAGCAGAA 
AATGAAGAAA AGAAAAAGGC TGAAGCACGA GCTAGAAACA AAAGAGAATC TGGAAAAGCA 
ACCTCATATG CAGAGCTTTG CAGTGAATAT CGAAAGCTTG TGAGGAACGG AAAACTTGCT 
TGCACCAGAG AGAACGATCC TATCCAGGGC CCAGATGGGA AAGTGCATGG CAACACCTGC 
TCCATGTGTG AGGTCTTCTT CCAAGCAGAA GAAGAAGAAA AGAAAAAGAA GGAAGGTAAA 
TCAAGAAACA AAAGACAATC TAAGAGTACA GCTTCCTTTG AGGAGTTGTG TAGTGAATAC 
CGCAAATCCA GGAAAAACGG ACGGCTTTTT TGCACCAGAG AGAATGACCC CATCCAGGGC 
CCAGATGGAA AAATGCATGG CAACACCTGC TCCATGTGTG AGGCCTTCTT TCAACAAGAA 
GAAAGAGCAA GAGCAAAGGC TAAAAGAGAA GCTGCAAAGG AAATCTGCAG TGAATTTCGG 
GACCAAGTGA GGAATGGAAC ACTTATATGC ACCAGGGAGC ATAATCCTGT CCGTGGCCCA 
GATGGCAAAA TGCATGGAAA CAAGTGTGCC ATGTGTGCCA GTGTGTTCAA ACTTGAAGAA 
GAAGAGAAGA AAAATGATAA AGAAGAAAAA GGGAAAGTCG AGGCTGAAAA AGTTAAGAGA 
GAAGCAGTTC AGGAGCTGTG CAGTGAATAT CGTCATTATG TGAGGAATGG ACGACTCCCC 
TGTACCAGAG AGAATGATCC TATTGAGGGT CTAGATGGGA AAATCCACGG CAACACCTGC 
TCCATGTGTG AAGCCTTCTT CCAGCAAGAA GCAAAAGAAA AAGAAAGAGC TGAACCCAGA 
GCAAAAGTCA AAAGAGAAGC TGAAAAGGAG ACATGCGATG AATTTCGGAG ACTTTTGCAA 
AATGGAAAAC TTTTCTGCAC AAGAGAAAAT GATCCTGTGC GTGGCCCAGA TGGCAAGACC 
CATGGCAACA AGTGTGCCAT GTGTAAGGCA GTCTTCCAGA AAGAAAATGA GGAAAGAAAG 
AGGAAAGAAG AGGAAGATCA GAGAAATGCT GCAGGACATG GTTCCAGTGG TGGTGGAGGA 
GGAAACACTC AGGACGAATG TGCTGAGTAT CGGGAACAAA TGAAAAATGG AAGACTCAGC 
TGTACTCGGG AGAGTGATCC TGTACGTGAT GCTGATGGCA AATCGTACAA CAATCAGTGT 
ACCATGTGTA AAGCAAAATT GGAAAGAGAA GCAGAGAGAA AAAATGAGTA TTCTCGCTCC 
AGATCAAATG GGACTGGATC AGAATCAGGG AAGGATACAT GTGATGAGTT TAGAAGCCAA 
ATGAAAAATG GAAAACTCAT CTGCACTCGA GAAAGTGACC CTGTCCGGGG TCCAGATGGC 
AAGACACATG GCAATAAGTG TACTATGTGT AAGGAAAAAC TGGAAAGGGA AGCAGCTGAA 
AAAAAAAAGA AAGAGGATGA AGACAGGAGC AATACAGGAG AAAGGAGCAA TACAGGAGAA 
AGGAGCAATG ACAAAGAGGA TCTGTGTCGT GAATTTCGAA GCATGCAGAG AAATGGAAAG 
CTTATCTGCA CCAGAGAAAA TAACCCTGTT CGAGGCCCAT ATGGCAAGAT GCACATCAAT 
AAATGTGCTA TGTGTCAGAG CATCTTTGAT CGAGAAGCTA ATGAAAGAAA AAAGAAAGAT 
GAAGAGAAAT CAAGTAGCAA GCCCTCAAAT AATGCAAAGG ACCAGTGCAG ACAGGTTCAG 
AATGAAGCGG AGGATGCAAA ATTTAGACAA CCTGGGCGTT CCTTGGCCTC TGTTGCCAGG 
ATGAGTACAG ATGAGTGCAG TGAATTTCGA AACTATATAA GGAACAATGA ACTCATCTGC 
CCTAGAGAGA ATGACCCAGT GCACGGTGCT GATGGAAAGT TCTATACAAA CAAGTGCTAC 
ATGTGCAGAG CTGTCTTTCT AACAGAAGCT TTGGAAAGGG CAAAGCTTCA AGAAAAGCCA 
TCCCATGTTA GAGCTTCTCA AGAGGAAGAC AGCCCAGACT CTTTCAGTTC TCTGGATTCT 
GAGATGTGCA AAGACTACCG AGTATTGCCC AGGATAGGTT ATCTTTGTCC AAAGGATTTA 
AAGCCTGTCT GTGGTGACGA TGGCCAAACC TACAACAATC CTTGCATGCT CTGTCATGAA 
AACCTGATAC GCCAAACAAA TACACACATC CGCAGTACAG GGAAGTGTGA GGAGAGCAGC 
ACCCCAGGAA CCACCGCAGC CAGCATGCCC CCGTCTGACG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121170.1
CDS	66..3350
Translation	MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNAKDQCRQVQNEAEDAKFRQPGRSLASVARMSTDECSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAVFLTEALERAKLQEKPSHVRASQEEDSPDSFSSLDSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKCEESSTPGTTAASMPPSDE

Target ORF information:

RefSeq Version	NM_001127698.2
Organism	Homo sapiens(human)
Definition	Homo sapiens serine peptidase inhibitor Kazal type 5 (SPINK5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127698.2

ORF Insert Sequence:

ATGAAGATAG CCACAGTGTC AGTGCTTCTG CCCTTGGCTC TTTGCCTCAT ACAAGATGCT 
GCCAGTAAGA ATGAAGATCA GGAAATGTGC CATGAATTTC AGGCATTTAT GAAAAATGGA 
AAACTGTTCT GTCCCCAGGA TAAGAAATTT TTTCAAAGTC TTGATGGAAT AATGTTCATC 
AATAAATGTG CCACGTGCAA AATGATACTG GAAAAAGAAG CAAAATCACA GAAGAGGGCC 
AGGCATTTAG CAAGAGCTCC CAAGGCTACT GCCCCAACAG AGCTGAATTG TGATGATTTT 
AAAAAAGGAG AAAGAGATGG GGATTTTATC TGTCCTGATT ATTATGAAGC TGTTTGTGGC 
ACAGATGGGA AAACATATGA CAACAGATGT GCACTGTGTG CTGAGAATGC GAAAACCGGG 
TCCCAAATTG GTGTAAAAAG TGAAGGGGAA TGTAAGAGCA GTAATCCAGA GCAGGATGTA 
TGCAGTGCTT TTCGGCCCTT TGTTAGAGAT GGAAGACTTG GATGCACAAG GGAAAATGAT 
CCTGTTCTTG GTCCTGATGG GAAGACGCAT GGCAATAAGT GTGCAATGTG TGCTGAGCTG 
TTTTTAAAAG AAGCTGAAAA TGCCAAGCGA GAGGGTGAAA CTAGAATTCG ACGAAATGCT 
GAAAAGGATT TTTGCAAGGA ATATGAAAAA CAAGTGAGAA ATGGAAGGCT TTTTTGTACA 
CGGGAGAGTG ATCCAGTCCG TGGCCCTGAC GGCAGGATGC ATGGCAACAA ATGTGCCCTG 
TGTGCTGAAA TTTTCAAGCA GCGTTTTTCA GAGGAAAACA GTAAAACAGA TCAAAATTTG 
GGAAAAGCTG AAGAAAAAAC TAAAGTTAAA AGAGAAATTG TGAAACTCTG CAGTCAATAT 
CAAAATCAGG CAAAGAATGG AATACTTTTC TGTACCAGAG AAAATGACCC TATTCGTGGT 
CCAGATGGGA AAATGCATGG CAACTTGTGT TCCATGTGTC AAGCCTACTT CCAAGCAGAA 
AATGAAGAAA AGAAAAAGGC TGAAGCACGA GCTAGAAACA AAAGAGAATC TGGAAAAGCA 
ACCTCATATG CAGAGCTTTG CAGTGAATAT CGAAAGCTTG TGAGGAACGG AAAACTTGCT 
TGCACCAGAG AGAACGATCC TATCCAGGGC CCAGATGGGA AAGTGCATGG CAACACCTGC 
TCCATGTGTG AGGTCTTCTT CCAAGCAGAA GAAGAAGAAA AGAAAAAGAA GGAAGGTAAA 
TCAAGAAACA AAAGACAATC TAAGAGTACA GCTTCCTTTG AGGAGTTGTG TAGTGAATAC 
CGCAAATCCA GGAAAAACGG ACGGCTTTTT TGCACCAGAG AGAATGACCC CATCCAGGGC 
CCAGATGGAA AAATGCATGG CAACACCTGC TCCATGTGTG AGGCCTTCTT TCAACAAGAA 
GAAAGAGCAA GAGCAAAGGC TAAAAGAGAA GCTGCAAAGG AAATCTGCAG TGAATTTCGG 
GACCAAGTGA GGAATGGAAC ACTTATATGC ACCAGGGAGC ATAATCCTGT CCGTGGCCCA 
GATGGCAAAA TGCATGGAAA CAAGTGTGCC ATGTGTGCCA GTGTGTTCAA ACTTGAAGAA 
GAAGAGAAGA AAAATGATAA AGAAGAAAAA GGGAAAGTCG AGGCTGAAAA AGTTAAGAGA 
GAAGCAGTTC AGGAGCTGTG CAGTGAATAT CGTCATTATG TGAGGAATGG ACGACTCCCC 
TGTACCAGAG AGAATGATCC TATTGAGGGT CTAGATGGGA AAATCCACGG CAACACCTGC 
TCCATGTGTG AAGCCTTCTT CCAGCAAGAA GCAAAAGAAA AAGAAAGAGC TGAACCCAGA 
GCAAAAGTCA AAAGAGAAGC TGAAAAGGAG ACATGCGATG AATTTCGGAG ACTTTTGCAA 
AATGGAAAAC TTTTCTGCAC AAGAGAAAAT GATCCTGTGC GTGGCCCAGA TGGCAAGACC 
CATGGCAACA AGTGTGCCAT GTGTAAGGCA GTCTTCCAGA AAGAAAATGA GGAAAGAAAG 
AGGAAAGAAG AGGAAGATCA GAGAAATGCT GCAGGACATG GTTCCAGTGG TGGTGGAGGA 
GGAAACACTC AGGACGAATG TGCTGAGTAT CGGGAACAAA TGAAAAATGG AAGACTCAGC 
TGTACTCGGG AGAGTGATCC TGTACGTGAT GCTGATGGCA AATCGTACAA CAATCAGTGT 
ACCATGTGTA AAGCAAAATT GGAAAGAGAA GCAGAGAGAA AAAATGAGTA TTCTCGCTCC 
AGATCAAATG GGACTGGATC AGAATCAGGG AAGGATACAT GTGATGAGTT TAGAAGCCAA 
ATGAAAAATG GAAAACTCAT CTGCACTCGA GAAAGTGACC CTGTCCGGGG TCCAGATGGC 
AAGACACATG GCAATAAGTG TACTATGTGT AAGGAAAAAC TGGAAAGGGA AGCAGCTGAA 
AAAAAAAAGA AAGAGGATGA AGACAGGAGC AATACAGGAG AAAGGAGCAA TACAGGAGAA 
AGGAGCAATG ACAAAGAGGA TCTGTGTCGT GAATTTCGAA GCATGCAGAG AAATGGAAAG 
CTTATCTGCA CCAGAGAAAA TAACCCTGTT CGAGGCCCAT ATGGCAAGAT GCACATCAAT 
AAATGTGCTA TGTGTCAGAG CATCTTTGAT CGAGAAGCTA ATGAAAGAAA AAAGAAAGAT 
GAAGAGAAAT CAAGTAGCAA GCCCTCAAAT AATGCAAAGG ACCAGTGCAG ACAGGTTCAG 
AATGAAGCGG AGGATGCAAA ATTTAGACAA CCTGGGCGTT CCTTGGCCTC TGTTGCCAGG 
ATGAGTACAG ATGAGTGCAG TGAATTTCGA AACTATATAA GGAACAATGA ACTCATCTGC 
CCTAGAGAGA ATGACCCAGT GCACGGTGCT GATGGAAAGT TCTATACAAA CAAGTGCTAC 
ATGTGCAGAG CTGTCTTTCT AACAGAAGCT TTGGAAAGGG CAAAGCTTCA AGAAAAGCCA 
TCCCATGTTA GAGCTTCTCA AGAGGAAGAC AGCCCAGACT CTTTCAGTTC TCTGGATTCT 
GAGATGTGCA AAGACTACCG AGTATTGCCC AGGATAGGTT ATCTTTGTCC AAAGGATTTA 
AAGCCTGTCT GTGGTGACGA TGGCCAAACC TACAACAATC CTTGCATGCT CTGTCATGAA 
AACCTGATAC GCCAAACAAA TACACACATC CGCAGTACAG GGAAGTGTGA GGAGAGCAGC 
ACCCCAGGAA CCACCGCAGC CAGCATGCCC CCGTCTGACG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPINK5 ( NM_006846.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006837.2 Homo sapiens serine peptidase inhibitor Kazal type 5 (SPINK5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu19403
Clone ID Related Accession (Same CDS sequence)	NM_006846.3 , NM_006846.4
Accession Version	NM_006846.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3195bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	serine protease inhibitor Kazal-type 5 isoform b preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ149927.1, AK307588.1, AK307648.1, AK025197.1, DR421881.1, AI341060.1 and AC116334.2. On Nov 30, 2019 this sequence version replaced NM_006846.3. Transcript Variant: This variant (2, also known as SPINK5f-l) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform b, also known as the LEKTIf-l isoform), compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ149927.1, AJ228139.2 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGATAG CCACAGTGTC AGTGCTTCTG CCCTTGGCTC TTTGCCTCAT ACAAGATGCT 
GCCAGTAAGA ATGAAGATCA GGAAATGTGC CATGAATTTC AGGCATTTAT GAAAAATGGA 
AAACTGTTCT GTCCCCAGGA TAAGAAATTT TTTCAAAGTC TTGATGGAAT AATGTTCATC 
AATAAATGTG CCACGTGCAA AATGATACTG GAAAAAGAAG CAAAATCACA GAAGAGGGCC 
AGGCATTTAG CAAGAGCTCC CAAGGCTACT GCCCCAACAG AGCTGAATTG TGATGATTTT 
AAAAAAGGAG AAAGAGATGG GGATTTTATC TGTCCTGATT ATTATGAAGC TGTTTGTGGC 
ACAGATGGGA AAACATATGA CAACAGATGT GCACTGTGTG CTGAGAATGC GAAAACCGGG 
TCCCAAATTG GTGTAAAAAG TGAAGGGGAA TGTAAGAGCA GTAATCCAGA GCAGGATGTA 
TGCAGTGCTT TTCGGCCCTT TGTTAGAGAT GGAAGACTTG GATGCACAAG GGAAAATGAT 
CCTGTTCTTG GTCCTGATGG GAAGACGCAT GGCAATAAGT GTGCAATGTG TGCTGAGCTG 
TTTTTAAAAG AAGCTGAAAA TGCCAAGCGA GAGGGTGAAA CTAGAATTCG ACGAAATGCT 
GAAAAGGATT TTTGCAAGGA ATATGAAAAA CAAGTGAGAA ATGGAAGGCT TTTTTGTACA 
CGGGAGAGTG ATCCAGTCCG TGGCCCTGAC GGCAGGATGC ATGGCAACAA ATGTGCCCTG 
TGTGCTGAAA TTTTCAAGCA GCGTTTTTCA GAGGAAAACA GTAAAACAGA TCAAAATTTG 
GGAAAAGCTG AAGAAAAAAC TAAAGTTAAA AGAGAAATTG TGAAACTCTG CAGTCAATAT 
CAAAATCAGG CAAAGAATGG AATACTTTTC TGTACCAGAG AAAATGACCC TATTCGTGGT 
CCAGATGGGA AAATGCATGG CAACTTGTGT TCCATGTGTC AAGCCTACTT CCAAGCAGAA 
AATGAAGAAA AGAAAAAGGC TGAAGCACGA GCTAGAAACA AAAGAGAATC TGGAAAAGCA 
ACCTCATATG CAGAGCTTTG CAGTGAATAT CGAAAGCTTG TGAGGAACGG AAAACTTGCT 
TGCACCAGAG AGAACGATCC TATCCAGGGC CCAGATGGGA AAGTGCATGG CAACACCTGC 
TCCATGTGTG AGGTCTTCTT CCAAGCAGAA GAAGAAGAAA AGAAAAAGAA GGAAGGTAAA 
TCAAGAAACA AAAGACAATC TAAGAGTACA GCTTCCTTTG AGGAGTTGTG TAGTGAATAC 
CGCAAATCCA GGAAAAACGG ACGGCTTTTT TGCACCAGAG AGAATGACCC CATCCAGGGC 
CCAGATGGAA AAATGCATGG CAACACCTGC TCCATGTGTG AGGCCTTCTT TCAACAAGAA 
GAAAGAGCAA GAGCAAAGGC TAAAAGAGAA GCTGCAAAGG AAATCTGCAG TGAATTTCGG 
GACCAAGTGA GGAATGGAAC ACTTATATGC ACCAGGGAGC ATAATCCTGT CCGTGGCCCA 
GATGGCAAAA TGCATGGAAA CAAGTGTGCC ATGTGTGCCA GTGTGTTCAA ACTTGAAGAA 
GAAGAGAAGA AAAATGATAA AGAAGAAAAA GGGAAAGTCG AGGCTGAAAA AGTTAAGAGA 
GAAGCAGTTC AGGAGCTGTG CAGTGAATAT CGTCATTATG TGAGGAATGG ACGACTCCCC 
TGTACCAGAG AGAATGATCC TATTGAGGGT CTAGATGGGA AAATCCACGG CAACACCTGC 
TCCATGTGTG AAGCCTTCTT CCAGCAAGAA GCAAAAGAAA AAGAAAGAGC TGAACCCAGA 
GCAAAAGTCA AAAGAGAAGC TGAAAAGGAG ACATGCGATG AATTTCGGAG ACTTTTGCAA 
AATGGAAAAC TTTTCTGCAC AAGAGAAAAT GATCCTGTGC GTGGCCCAGA TGGCAAGACC 
CATGGCAACA AGTGTGCCAT GTGTAAGGCA GTCTTCCAGA AAGAAAATGA GGAAAGAAAG 
AGGAAAGAAG AGGAAGATCA GAGAAATGCT GCAGGACATG GTTCCAGTGG TGGTGGAGGA 
GGAAACACTC AGGACGAATG TGCTGAGTAT CGGGAACAAA TGAAAAATGG AAGACTCAGC 
TGTACTCGGG AGAGTGATCC TGTACGTGAT GCTGATGGCA AATCGTACAA CAATCAGTGT 
ACCATGTGTA AAGCAAAATT GGAAAGAGAA GCAGAGAGAA AAAATGAGTA TTCTCGCTCC 
AGATCAAATG GGACTGGATC AGAATCAGGG AAGGATACAT GTGATGAGTT TAGAAGCCAA 
ATGAAAAATG GAAAACTCAT CTGCACTCGA GAAAGTGACC CTGTCCGGGG TCCAGATGGC 
AAGACACATG GCAATAAGTG TACTATGTGT AAGGAAAAAC TGGAAAGGGA AGCAGCTGAA 
AAAAAAAAGA AAGAGGATGA AGACAGGAGC AATACAGGAG AAAGGAGCAA TACAGGAGAA 
AGGAGCAATG ACAAAGAGGA TCTGTGTCGT GAATTTCGAA GCATGCAGAG AAATGGAAAG 
CTTATCTGCA CCAGAGAAAA TAACCCTGTT CGAGGCCCAT ATGGCAAGAT GCACATCAAT 
AAATGTGCTA TGTGTCAGAG CATCTTTGAT CGAGAAGCTA ATGAAAGAAA AAAGAAAGAT 
GAAGAGAAAT CAAGTAGCAA GCCCTCAAAT AATGCAAAGG ATGAGTGCAG TGAATTTCGA 
AACTATATAA GGAACAATGA ACTCATCTGC CCTAGAGAGA ATGACCCAGT GCACGGTGCT 
GATGGAAAGT TCTATACAAA CAAGTGCTAC ATGTGCAGAG CTGTCTTTCT AACAGAAGCT 
TTGGAAAGGG CAAAGCTTCA AGAAAAGCCA TCCCATGTTA GAGCTTCTCA AGAGGAAGAC 
AGCCCAGACT CTTTCAGTTC TCTGGATTCT GAGATGTGCA AAGACTACCG AGTATTGCCC 
AGGATAGGTT ATCTTTGTCC AAAGGATTTA AAGCCTGTCT GTGGTGACGA TGGCCAAACC 
TACAACAATC CTTGCATGCT CTGTCATGAA AACCTGATAC GCCAAACAAA TACACACATC 
CGCAGTACAG GGAAGTGTGA GGAGAGCAGC ACCCCAGGAA CCACCGCAGC CAGCATGCCC 
CCGTCTGACG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006837.2
CDS	66..3260
Translation	MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNAKDECSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAVFLTEALERAKLQEKPSHVRASQEEDSPDSFSSLDSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKCEESSTPGTTAASMPPSDE

Target ORF information:

RefSeq Version	NM_006846.4
Organism	Homo sapiens(human)
Definition	Homo sapiens serine peptidase inhibitor Kazal type 5 (SPINK5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006846.4

ORF Insert Sequence:

ATGAAGATAG CCACAGTGTC AGTGCTTCTG CCCTTGGCTC TTTGCCTCAT ACAAGATGCT 
GCCAGTAAGA ATGAAGATCA GGAAATGTGC CATGAATTTC AGGCATTTAT GAAAAATGGA 
AAACTGTTCT GTCCCCAGGA TAAGAAATTT TTTCAAAGTC TTGATGGAAT AATGTTCATC 
AATAAATGTG CCACGTGCAA AATGATACTG GAAAAAGAAG CAAAATCACA GAAGAGGGCC 
AGGCATTTAG CAAGAGCTCC CAAGGCTACT GCCCCAACAG AGCTGAATTG TGATGATTTT 
AAAAAAGGAG AAAGAGATGG GGATTTTATC TGTCCTGATT ATTATGAAGC TGTTTGTGGC 
ACAGATGGGA AAACATATGA CAACAGATGT GCACTGTGTG CTGAGAATGC GAAAACCGGG 
TCCCAAATTG GTGTAAAAAG TGAAGGGGAA TGTAAGAGCA GTAATCCAGA GCAGGATGTA 
TGCAGTGCTT TTCGGCCCTT TGTTAGAGAT GGAAGACTTG GATGCACAAG GGAAAATGAT 
CCTGTTCTTG GTCCTGATGG GAAGACGCAT GGCAATAAGT GTGCAATGTG TGCTGAGCTG 
TTTTTAAAAG AAGCTGAAAA TGCCAAGCGA GAGGGTGAAA CTAGAATTCG ACGAAATGCT 
GAAAAGGATT TTTGCAAGGA ATATGAAAAA CAAGTGAGAA ATGGAAGGCT TTTTTGTACA 
CGGGAGAGTG ATCCAGTCCG TGGCCCTGAC GGCAGGATGC ATGGCAACAA ATGTGCCCTG 
TGTGCTGAAA TTTTCAAGCA GCGTTTTTCA GAGGAAAACA GTAAAACAGA TCAAAATTTG 
GGAAAAGCTG AAGAAAAAAC TAAAGTTAAA AGAGAAATTG TGAAACTCTG CAGTCAATAT 
CAAAATCAGG CAAAGAATGG AATACTTTTC TGTACCAGAG AAAATGACCC TATTCGTGGT 
CCAGATGGGA AAATGCATGG CAACTTGTGT TCCATGTGTC AAGCCTACTT CCAAGCAGAA 
AATGAAGAAA AGAAAAAGGC TGAAGCACGA GCTAGAAACA AAAGAGAATC TGGAAAAGCA 
ACCTCATATG CAGAGCTTTG CAGTGAATAT CGAAAGCTTG TGAGGAACGG AAAACTTGCT 
TGCACCAGAG AGAACGATCC TATCCAGGGC CCAGATGGGA AAGTGCATGG CAACACCTGC 
TCCATGTGTG AGGTCTTCTT CCAAGCAGAA GAAGAAGAAA AGAAAAAGAA GGAAGGTAAA 
TCAAGAAACA AAAGACAATC TAAGAGTACA GCTTCCTTTG AGGAGTTGTG TAGTGAATAC 
CGCAAATCCA GGAAAAACGG ACGGCTTTTT TGCACCAGAG AGAATGACCC CATCCAGGGC 
CCAGATGGAA AAATGCATGG CAACACCTGC TCCATGTGTG AGGCCTTCTT TCAACAAGAA 
GAAAGAGCAA GAGCAAAGGC TAAAAGAGAA GCTGCAAAGG AAATCTGCAG TGAATTTCGG 
GACCAAGTGA GGAATGGAAC ACTTATATGC ACCAGGGAGC ATAATCCTGT CCGTGGCCCA 
GATGGCAAAA TGCATGGAAA CAAGTGTGCC ATGTGTGCCA GTGTGTTCAA ACTTGAAGAA 
GAAGAGAAGA AAAATGATAA AGAAGAAAAA GGGAAAGTCG AGGCTGAAAA AGTTAAGAGA 
GAAGCAGTTC AGGAGCTGTG CAGTGAATAT CGTCATTATG TGAGGAATGG ACGACTCCCC 
TGTACCAGAG AGAATGATCC TATTGAGGGT CTAGATGGGA AAATCCACGG CAACACCTGC 
TCCATGTGTG AAGCCTTCTT CCAGCAAGAA GCAAAAGAAA AAGAAAGAGC TGAACCCAGA 
GCAAAAGTCA AAAGAGAAGC TGAAAAGGAG ACATGCGATG AATTTCGGAG ACTTTTGCAA 
AATGGAAAAC TTTTCTGCAC AAGAGAAAAT GATCCTGTGC GTGGCCCAGA TGGCAAGACC 
CATGGCAACA AGTGTGCCAT GTGTAAGGCA GTCTTCCAGA AAGAAAATGA GGAAAGAAAG 
AGGAAAGAAG AGGAAGATCA GAGAAATGCT GCAGGACATG GTTCCAGTGG TGGTGGAGGA 
GGAAACACTC AGGACGAATG TGCTGAGTAT CGGGAACAAA TGAAAAATGG AAGACTCAGC 
TGTACTCGGG AGAGTGATCC TGTACGTGAT GCTGATGGCA AATCGTACAA CAATCAGTGT 
ACCATGTGTA AAGCAAAATT GGAAAGAGAA GCAGAGAGAA AAAATGAGTA TTCTCGCTCC 
AGATCAAATG GGACTGGATC AGAATCAGGG AAGGATACAT GTGATGAGTT TAGAAGCCAA 
ATGAAAAATG GAAAACTCAT CTGCACTCGA GAAAGTGACC CTGTCCGGGG TCCAGATGGC 
AAGACACATG GCAATAAGTG TACTATGTGT AAGGAAAAAC TGGAAAGGGA AGCAGCTGAA 
AAAAAAAAGA AAGAGGATGA AGACAGGAGC AATACAGGAG AAAGGAGCAA TACAGGAGAA 
AGGAGCAATG ACAAAGAGGA TCTGTGTCGT GAATTTCGAA GCATGCAGAG AAATGGAAAG 
CTTATCTGCA CCAGAGAAAA TAACCCTGTT CGAGGCCCAT ATGGCAAGAT GCACATCAAT 
AAATGTGCTA TGTGTCAGAG CATCTTTGAT CGAGAAGCTA ATGAAAGAAA AAAGAAAGAT 
GAAGAGAAAT CAAGTAGCAA GCCCTCAAAT AATGCAAAGG ATGAGTGCAG TGAATTTCGA 
AACTATATAA GGAACAATGA ACTCATCTGC CCTAGAGAGA ATGACCCAGT GCACGGTGCT 
GATGGAAAGT TCTATACAAA CAAGTGCTAC ATGTGCAGAG CTGTCTTTCT AACAGAAGCT 
TTGGAAAGGG CAAAGCTTCA AGAAAAGCCA TCCCATGTTA GAGCTTCTCA AGAGGAAGAC 
AGCCCAGACT CTTTCAGTTC TCTGGATTCT GAGATGTGCA AAGACTACCG AGTATTGCCC 
AGGATAGGTT ATCTTTGTCC AAAGGATTTA AAGCCTGTCT GTGGTGACGA TGGCCAAACC 
TACAACAATC CTTGCATGCT CTGTCATGAA AACCTGATAC GCCAAACAAA TACACACATC 
CGCAGTACAG GGAAGTGTGA GGAGAGCAGC ACCCCAGGAA CCACCGCAGC CAGCATGCCC 
CCGTCTGACG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPINK5 ( NM_006846.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006837.2 Homo sapiens serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 2, mRNA.

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CloneID	OHu19403
Clone ID Related Accession (Same CDS sequence)	NM_006846.3 , NM_006846.4
Accession Version	NM_006846.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3195bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	serine protease inhibitor Kazal-type 5 isoform b preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ149927.1, AK307588.1, AK307648.1, AK025197.1, DR421881.1 and AI341060.1. On May 29, 2008 this sequence version replaced NM_006846.2. Transcript Variant: This variant (2, also known as SPINK5f-l) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform b, also known as the LEKTIf-l isoform), compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ149927.1, AJ228139.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGATAG CCACAGTGTC AGTGCTTCTG CCCTTGGCTC TTTGCCTCAT ACAAGATGCT 
GCCAGTAAGA ATGAAGATCA GGAAATGTGC CATGAATTTC AGGCATTTAT GAAAAATGGA 
AAACTGTTCT GTCCCCAGGA TAAGAAATTT TTTCAAAGTC TTGATGGAAT AATGTTCATC 
AATAAATGTG CCACGTGCAA AATGATACTG GAAAAAGAAG CAAAATCACA GAAGAGGGCC 
AGGCATTTAG CAAGAGCTCC CAAGGCTACT GCCCCAACAG AGCTGAATTG TGATGATTTT 
AAAAAAGGAG AAAGAGATGG GGATTTTATC TGTCCTGATT ATTATGAAGC TGTTTGTGGC 
ACAGATGGGA AAACATATGA CAACAGATGT GCACTGTGTG CTGAGAATGC GAAAACCGGG 
TCCCAAATTG GTGTAAAAAG TGAAGGGGAA TGTAAGAGCA GTAATCCAGA GCAGGATGTA 
TGCAGTGCTT TTCGGCCCTT TGTTAGAGAT GGAAGACTTG GATGCACAAG GGAAAATGAT 
CCTGTTCTTG GTCCTGATGG GAAGACGCAT GGCAATAAGT GTGCAATGTG TGCTGAGCTG 
TTTTTAAAAG AAGCTGAAAA TGCCAAGCGA GAGGGTGAAA CTAGAATTCG ACGAAATGCT 
GAAAAGGATT TTTGCAAGGA ATATGAAAAA CAAGTGAGAA ATGGAAGGCT TTTTTGTACA 
CGGGAGAGTG ATCCAGTCCG TGGCCCTGAC GGCAGGATGC ATGGCAACAA ATGTGCCCTG 
TGTGCTGAAA TTTTCAAGCA GCGTTTTTCA GAGGAAAACA GTAAAACAGA TCAAAATTTG 
GGAAAAGCTG AAGAAAAAAC TAAAGTTAAA AGAGAAATTG TGAAACTCTG CAGTCAATAT 
CAAAATCAGG CAAAGAATGG AATACTTTTC TGTACCAGAG AAAATGACCC TATTCGTGGT 
CCAGATGGGA AAATGCATGG CAACTTGTGT TCCATGTGTC AAGCCTACTT CCAAGCAGAA 
AATGAAGAAA AGAAAAAGGC TGAAGCACGA GCTAGAAACA AAAGAGAATC TGGAAAAGCA 
ACCTCATATG CAGAGCTTTG CAGTGAATAT CGAAAGCTTG TGAGGAACGG AAAACTTGCT 
TGCACCAGAG AGAACGATCC TATCCAGGGC CCAGATGGGA AAGTGCATGG CAACACCTGC 
TCCATGTGTG AGGTCTTCTT CCAAGCAGAA GAAGAAGAAA AGAAAAAGAA GGAAGGTAAA 
TCAAGAAACA AAAGACAATC TAAGAGTACA GCTTCCTTTG AGGAGTTGTG TAGTGAATAC 
CGCAAATCCA GGAAAAACGG ACGGCTTTTT TGCACCAGAG AGAATGACCC CATCCAGGGC 
CCAGATGGAA AAATGCATGG CAACACCTGC TCCATGTGTG AGGCCTTCTT TCAACAAGAA 
GAAAGAGCAA GAGCAAAGGC TAAAAGAGAA GCTGCAAAGG AAATCTGCAG TGAATTTCGG 
GACCAAGTGA GGAATGGAAC ACTTATATGC ACCAGGGAGC ATAATCCTGT CCGTGGCCCA 
GATGGCAAAA TGCATGGAAA CAAGTGTGCC ATGTGTGCCA GTGTGTTCAA ACTTGAAGAA 
GAAGAGAAGA AAAATGATAA AGAAGAAAAA GGGAAAGTCG AGGCTGAAAA AGTTAAGAGA 
GAAGCAGTTC AGGAGCTGTG CAGTGAATAT CGTCATTATG TGAGGAATGG ACGACTCCCC 
TGTACCAGAG AGAATGATCC TATTGAGGGT CTAGATGGGA AAATCCACGG CAACACCTGC 
TCCATGTGTG AAGCCTTCTT CCAGCAAGAA GCAAAAGAAA AAGAAAGAGC TGAACCCAGA 
GCAAAAGTCA AAAGAGAAGC TGAAAAGGAG ACATGCGATG AATTTCGGAG ACTTTTGCAA 
AATGGAAAAC TTTTCTGCAC AAGAGAAAAT GATCCTGTGC GTGGCCCAGA TGGCAAGACC 
CATGGCAACA AGTGTGCCAT GTGTAAGGCA GTCTTCCAGA AAGAAAATGA GGAAAGAAAG 
AGGAAAGAAG AGGAAGATCA GAGAAATGCT GCAGGACATG GTTCCAGTGG TGGTGGAGGA 
GGAAACACTC AGGACGAATG TGCTGAGTAT CGGGAACAAA TGAAAAATGG AAGACTCAGC 
TGTACTCGGG AGAGTGATCC TGTACGTGAT GCTGATGGCA AATCGTACAA CAATCAGTGT 
ACCATGTGTA AAGCAAAATT GGAAAGAGAA GCAGAGAGAA AAAATGAGTA TTCTCGCTCC 
AGATCAAATG GGACTGGATC AGAATCAGGG AAGGATACAT GTGATGAGTT TAGAAGCCAA 
ATGAAAAATG GAAAACTCAT CTGCACTCGA GAAAGTGACC CTGTCCGGGG TCCAGATGGC 
AAGACACATG GCAATAAGTG TACTATGTGT AAGGAAAAAC TGGAAAGGGA AGCAGCTGAA 
AAAAAAAAGA AAGAGGATGA AGACAGGAGC AATACAGGAG AAAGGAGCAA TACAGGAGAA 
AGGAGCAATG ACAAAGAGGA TCTGTGTCGT GAATTTCGAA GCATGCAGAG AAATGGAAAG 
CTTATCTGCA CCAGAGAAAA TAACCCTGTT CGAGGCCCAT ATGGCAAGAT GCACATCAAT 
AAATGTGCTA TGTGTCAGAG CATCTTTGAT CGAGAAGCTA ATGAAAGAAA AAAGAAAGAT 
GAAGAGAAAT CAAGTAGCAA GCCCTCAAAT AATGCAAAGG ATGAGTGCAG TGAATTTCGA 
AACTATATAA GGAACAATGA ACTCATCTGC CCTAGAGAGA ATGACCCAGT GCACGGTGCT 
GATGGAAAGT TCTATACAAA CAAGTGCTAC ATGTGCAGAG CTGTCTTTCT AACAGAAGCT 
TTGGAAAGGG CAAAGCTTCA AGAAAAGCCA TCCCATGTTA GAGCTTCTCA AGAGGAAGAC 
AGCCCAGACT CTTTCAGTTC TCTGGATTCT GAGATGTGCA AAGACTACCG AGTATTGCCC 
AGGATAGGTT ATCTTTGTCC AAAGGATTTA AAGCCTGTCT GTGGTGACGA TGGCCAAACC 
TACAACAATC CTTGCATGCT CTGTCATGAA AACCTGATAC GCCAAACAAA TACACACATC 
CGCAGTACAG GGAAGTGTGA GGAGAGCAGC ACCCCAGGAA CCACCGCAGC CAGCATGCCC 
CCGTCTGACG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006837.2
CDS	74..3268
Translation	MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNAKDECSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAVFLTEALERAKLQEKPSHVRASQEEDSPDSFSSLDSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKCEESSTPGTTAASMPPSDE

Target ORF information:

RefSeq Version	NM_006846.3
Organism	Homo sapiens(human)
Definition	Homo sapiens serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006846.3

ORF Insert Sequence:

ATGAAGATAG CCACAGTGTC AGTGCTTCTG CCCTTGGCTC TTTGCCTCAT ACAAGATGCT 
GCCAGTAAGA ATGAAGATCA GGAAATGTGC CATGAATTTC AGGCATTTAT GAAAAATGGA 
AAACTGTTCT GTCCCCAGGA TAAGAAATTT TTTCAAAGTC TTGATGGAAT AATGTTCATC 
AATAAATGTG CCACGTGCAA AATGATACTG GAAAAAGAAG CAAAATCACA GAAGAGGGCC 
AGGCATTTAG CAAGAGCTCC CAAGGCTACT GCCCCAACAG AGCTGAATTG TGATGATTTT 
AAAAAAGGAG AAAGAGATGG GGATTTTATC TGTCCTGATT ATTATGAAGC TGTTTGTGGC 
ACAGATGGGA AAACATATGA CAACAGATGT GCACTGTGTG CTGAGAATGC GAAAACCGGG 
TCCCAAATTG GTGTAAAAAG TGAAGGGGAA TGTAAGAGCA GTAATCCAGA GCAGGATGTA 
TGCAGTGCTT TTCGGCCCTT TGTTAGAGAT GGAAGACTTG GATGCACAAG GGAAAATGAT 
CCTGTTCTTG GTCCTGATGG GAAGACGCAT GGCAATAAGT GTGCAATGTG TGCTGAGCTG 
TTTTTAAAAG AAGCTGAAAA TGCCAAGCGA GAGGGTGAAA CTAGAATTCG ACGAAATGCT 
GAAAAGGATT TTTGCAAGGA ATATGAAAAA CAAGTGAGAA ATGGAAGGCT TTTTTGTACA 
CGGGAGAGTG ATCCAGTCCG TGGCCCTGAC GGCAGGATGC ATGGCAACAA ATGTGCCCTG 
TGTGCTGAAA TTTTCAAGCA GCGTTTTTCA GAGGAAAACA GTAAAACAGA TCAAAATTTG 
GGAAAAGCTG AAGAAAAAAC TAAAGTTAAA AGAGAAATTG TGAAACTCTG CAGTCAATAT 
CAAAATCAGG CAAAGAATGG AATACTTTTC TGTACCAGAG AAAATGACCC TATTCGTGGT 
CCAGATGGGA AAATGCATGG CAACTTGTGT TCCATGTGTC AAGCCTACTT CCAAGCAGAA 
AATGAAGAAA AGAAAAAGGC TGAAGCACGA GCTAGAAACA AAAGAGAATC TGGAAAAGCA 
ACCTCATATG CAGAGCTTTG CAGTGAATAT CGAAAGCTTG TGAGGAACGG AAAACTTGCT 
TGCACCAGAG AGAACGATCC TATCCAGGGC CCAGATGGGA AAGTGCATGG CAACACCTGC 
TCCATGTGTG AGGTCTTCTT CCAAGCAGAA GAAGAAGAAA AGAAAAAGAA GGAAGGTAAA 
TCAAGAAACA AAAGACAATC TAAGAGTACA GCTTCCTTTG AGGAGTTGTG TAGTGAATAC 
CGCAAATCCA GGAAAAACGG ACGGCTTTTT TGCACCAGAG AGAATGACCC CATCCAGGGC 
CCAGATGGAA AAATGCATGG CAACACCTGC TCCATGTGTG AGGCCTTCTT TCAACAAGAA 
GAAAGAGCAA GAGCAAAGGC TAAAAGAGAA GCTGCAAAGG AAATCTGCAG TGAATTTCGG 
GACCAAGTGA GGAATGGAAC ACTTATATGC ACCAGGGAGC ATAATCCTGT CCGTGGCCCA 
GATGGCAAAA TGCATGGAAA CAAGTGTGCC ATGTGTGCCA GTGTGTTCAA ACTTGAAGAA 
GAAGAGAAGA AAAATGATAA AGAAGAAAAA GGGAAAGTCG AGGCTGAAAA AGTTAAGAGA 
GAAGCAGTTC AGGAGCTGTG CAGTGAATAT CGTCATTATG TGAGGAATGG ACGACTCCCC 
TGTACCAGAG AGAATGATCC TATTGAGGGT CTAGATGGGA AAATCCACGG CAACACCTGC 
TCCATGTGTG AAGCCTTCTT CCAGCAAGAA GCAAAAGAAA AAGAAAGAGC TGAACCCAGA 
GCAAAAGTCA AAAGAGAAGC TGAAAAGGAG ACATGCGATG AATTTCGGAG ACTTTTGCAA 
AATGGAAAAC TTTTCTGCAC AAGAGAAAAT GATCCTGTGC GTGGCCCAGA TGGCAAGACC 
CATGGCAACA AGTGTGCCAT GTGTAAGGCA GTCTTCCAGA AAGAAAATGA GGAAAGAAAG 
AGGAAAGAAG AGGAAGATCA GAGAAATGCT GCAGGACATG GTTCCAGTGG TGGTGGAGGA 
GGAAACACTC AGGACGAATG TGCTGAGTAT CGGGAACAAA TGAAAAATGG AAGACTCAGC 
TGTACTCGGG AGAGTGATCC TGTACGTGAT GCTGATGGCA AATCGTACAA CAATCAGTGT 
ACCATGTGTA AAGCAAAATT GGAAAGAGAA GCAGAGAGAA AAAATGAGTA TTCTCGCTCC 
AGATCAAATG GGACTGGATC AGAATCAGGG AAGGATACAT GTGATGAGTT TAGAAGCCAA 
ATGAAAAATG GAAAACTCAT CTGCACTCGA GAAAGTGACC CTGTCCGGGG TCCAGATGGC 
AAGACACATG GCAATAAGTG TACTATGTGT AAGGAAAAAC TGGAAAGGGA AGCAGCTGAA 
AAAAAAAAGA AAGAGGATGA AGACAGGAGC AATACAGGAG AAAGGAGCAA TACAGGAGAA 
AGGAGCAATG ACAAAGAGGA TCTGTGTCGT GAATTTCGAA GCATGCAGAG AAATGGAAAG 
CTTATCTGCA CCAGAGAAAA TAACCCTGTT CGAGGCCCAT ATGGCAAGAT GCACATCAAT 
AAATGTGCTA TGTGTCAGAG CATCTTTGAT CGAGAAGCTA ATGAAAGAAA AAAGAAAGAT 
GAAGAGAAAT CAAGTAGCAA GCCCTCAAAT AATGCAAAGG ATGAGTGCAG TGAATTTCGA 
AACTATATAA GGAACAATGA ACTCATCTGC CCTAGAGAGA ATGACCCAGT GCACGGTGCT 
GATGGAAAGT TCTATACAAA CAAGTGCTAC ATGTGCAGAG CTGTCTTTCT AACAGAAGCT 
TTGGAAAGGG CAAAGCTTCA AGAAAAGCCA TCCCATGTTA GAGCTTCTCA AGAGGAAGAC 
AGCCCAGACT CTTTCAGTTC TCTGGATTCT GAGATGTGCA AAGACTACCG AGTATTGCCC 
AGGATAGGTT ATCTTTGTCC AAAGGATTTA AAGCCTGTCT GTGGTGACGA TGGCCAAACC 
TACAACAATC CTTGCATGCT CTGTCATGAA AACCTGATAC GCCAAACAAA TACACACATC 
CGCAGTACAG GGAAGTGTGA GGAGAGCAGC ACCCCAGGAA CCACCGCAGC CAGCATGCCC 
CCGTCTGACG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPINK5 ( NM_001127699.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001121171.1 Homo sapiens serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu31774
Clone ID Related Accession (Same CDS sequence)	NM_001127699.1 , NM_001127699.2
Accession Version	NM_001127699.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2751bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	serine protease inhibitor Kazal-type 5 isoform c preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ149929.1, AK307588.1, AK307648.1 and AK025197.1. Transcript Variant: This variant (3, also known as SPINK5sh) differs in the 3' UTR and lacks several exons in the 3' coding region, compared to variant 1. The resulting protein (isoform c, also known as the LEKTIsh or short isoform) has a distinct C-terminus and is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ149929.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAAGATAG CCACAGTGTC AGTGCTTCTG CCCTTGGCTC TTTGCCTCAT ACAAGATGCT 
GCCAGTAAGA ATGAAGATCA GGAAATGTGC CATGAATTTC AGGCATTTAT GAAAAATGGA 
AAACTGTTCT GTCCCCAGGA TAAGAAATTT TTTCAAAGTC TTGATGGAAT AATGTTCATC 
AATAAATGTG CCACGTGCAA AATGATACTG GAAAAAGAAG CAAAATCACA GAAGAGGGCC 
AGGCATTTAG CAAGAGCTCC CAAGGCTACT GCCCCAACAG AGCTGAATTG TGATGATTTT 
AAAAAAGGAG AAAGAGATGG GGATTTTATC TGTCCTGATT ATTATGAAGC TGTTTGTGGC 
ACAGATGGGA AAACATATGA CAACAGATGT GCACTGTGTG CTGAGAATGC GAAAACCGGG 
TCCCAAATTG GTGTAAAAAG TGAAGGGGAA TGTAAGAGCA GTAATCCAGA GCAGGATGTA 
TGCAGTGCTT TTCGGCCCTT TGTTAGAGAT GGAAGACTTG GATGCACAAG GGAAAATGAT 
CCTGTTCTTG GTCCTGATGG GAAGACGCAT GGCAATAAGT GTGCAATGTG TGCTGAGCTG 
TTTTTAAAAG AAGCTGAAAA TGCCAAGCGA GAGGGTGAAA CTAGAATTCG ACGAAATGCT 
GAAAAGGATT TTTGCAAGGA ATATGAAAAA CAAGTGAGAA ATGGAAGGCT TTTTTGTACA 
CGGGAGAGTG ATCCAGTCCG TGGCCCTGAC GGCAGGATGC ATGGCAACAA ATGTGCCCTG 
TGTGCTGAAA TTTTCAAGCA GCGTTTTTCA GAGGAAAACA GTAAAACAGA TCAAAATTTG 
GGAAAAGCTG AAGAAAAAAC TAAAGTTAAA AGAGAAATTG TGAAACTCTG CAGTCAATAT 
CAAAATCAGG CAAAGAATGG AATACTTTTC TGTACCAGAG AAAATGACCC TATTCGTGGT 
CCAGATGGGA AAATGCATGG CAACTTGTGT TCCATGTGTC AAGCCTACTT CCAAGCAGAA 
AATGAAGAAA AGAAAAAGGC TGAAGCACGA GCTAGAAACA AAAGAGAATC TGGAAAAGCA 
ACCTCATATG CAGAGCTTTG CAGTGAATAT CGAAAGCTTG TGAGGAACGG AAAACTTGCT 
TGCACCAGAG AGAACGATCC TATCCAGGGC CCAGATGGGA AAGTGCATGG CAACACCTGC 
TCCATGTGTG AGGTCTTCTT CCAAGCAGAA GAAGAAGAAA AGAAAAAGAA GGAAGGTAAA 
TCAAGAAACA AAAGACAATC TAAGAGTACA GCTTCCTTTG AGGAGTTGTG TAGTGAATAC 
CGCAAATCCA GGAAAAACGG ACGGCTTTTT TGCACCAGAG AGAATGACCC CATCCAGGGC 
CCAGATGGAA AAATGCATGG CAACACCTGC TCCATGTGTG AGGCCTTCTT TCAACAAGAA 
GAAAGAGCAA GAGCAAAGGC TAAAAGAGAA GCTGCAAAGG AAATCTGCAG TGAATTTCGG 
GACCAAGTGA GGAATGGAAC ACTTATATGC ACCAGGGAGC ATAATCCTGT CCGTGGCCCA 
GATGGCAAAA TGCATGGAAA CAAGTGTGCC ATGTGTGCCA GTGTGTTCAA ACTTGAAGAA 
GAAGAGAAGA AAAATGATAA AGAAGAAAAA GGGAAAGTCG AGGCTGAAAA AGTTAAGAGA 
GAAGCAGTTC AGGAGCTGTG CAGTGAATAT CGTCATTATG TGAGGAATGG ACGACTCCCC 
TGTACCAGAG AGAATGATCC TATTGAGGGT CTAGATGGGA AAATCCACGG CAACACCTGC 
TCCATGTGTG AAGCCTTCTT CCAGCAAGAA GCAAAAGAAA AAGAAAGAGC TGAACCCAGA 
GCAAAAGTCA AAAGAGAAGC TGAAAAGGAG ACATGCGATG AATTTCGGAG ACTTTTGCAA 
AATGGAAAAC TTTTCTGCAC AAGAGAAAAT GATCCTGTGC GTGGCCCAGA TGGCAAGACC 
CATGGCAACA AGTGTGCCAT GTGTAAGGCA GTCTTCCAGA AAGAAAATGA GGAAAGAAAG 
AGGAAAGAAG AGGAAGATCA GAGAAATGCT GCAGGACATG GTTCCAGTGG TGGTGGAGGA 
GGAAACACTC AGGACGAATG TGCTGAGTAT CGGGAACAAA TGAAAAATGG AAGACTCAGC 
TGTACTCGGG AGAGTGATCC TGTACGTGAT GCTGATGGCA AATCGTACAA CAATCAGTGT 
ACCATGTGTA AAGCAAAATT GGAAAGAGAA GCAGAGAGAA AAAATGAGTA TTCTCGCTCC 
AGATCAAATG GGACTGGATC AGAATCAGGG AAGGATACAT GTGATGAGTT TAGAAGCCAA 
ATGAAAAATG GAAAACTCAT CTGCACTCGA GAAAGTGACC CTGTCCGGGG TCCAGATGGC 
AAGACACATG GCAATAAGTG TACTATGTGT AAGGAAAAAC TGGAAAGGGA AGCAGCTGAA 
AAAAAAAAGA AAGAGGATGA AGACAGGAGC AATACAGGAG AAAGGAGCAA TACAGGAGAA 
AGGAGCAATG ACAAAGAGGA TCTGTGTCGT GAATTTCGAA GCATGCAGAG AAATGGAAAG 
CTTATCTGCA CCAGAGAAAA TAACCCTGTT CGAGGCCCAT ATGGCAAGAT GCACATCAAT 
AAATGTGCTA TGTGTCAGAG CATCTTTGAT CGAGAAGCTA ATGAAAGAAA AAAGAAAGAT 
GAAGAGAAAT CAAGTAGCAA GCCCTCAAAT AATGCAAAGG TTATTTATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121171.1
CDS	74..2824
Translation	MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNAKVIY

Target ORF information:

RefSeq Version	NM_001127699.1
Organism	Homo sapiens(human)
Definition	Homo sapiens serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127699.1

ORF Insert Sequence:

ATGAAGATAG CCACAGTGTC AGTGCTTCTG CCCTTGGCTC TTTGCCTCAT ACAAGATGCT 
GCCAGTAAGA ATGAAGATCA GGAAATGTGC CATGAATTTC AGGCATTTAT GAAAAATGGA 
AAACTGTTCT GTCCCCAGGA TAAGAAATTT TTTCAAAGTC TTGATGGAAT AATGTTCATC 
AATAAATGTG CCACGTGCAA AATGATACTG GAAAAAGAAG CAAAATCACA GAAGAGGGCC 
AGGCATTTAG CAAGAGCTCC CAAGGCTACT GCCCCAACAG AGCTGAATTG TGATGATTTT 
AAAAAAGGAG AAAGAGATGG GGATTTTATC TGTCCTGATT ATTATGAAGC TGTTTGTGGC 
ACAGATGGGA AAACATATGA CAACAGATGT GCACTGTGTG CTGAGAATGC GAAAACCGGG 
TCCCAAATTG GTGTAAAAAG TGAAGGGGAA TGTAAGAGCA GTAATCCAGA GCAGGATGTA 
TGCAGTGCTT TTCGGCCCTT TGTTAGAGAT GGAAGACTTG GATGCACAAG GGAAAATGAT 
CCTGTTCTTG GTCCTGATGG GAAGACGCAT GGCAATAAGT GTGCAATGTG TGCTGAGCTG 
TTTTTAAAAG AAGCTGAAAA TGCCAAGCGA GAGGGTGAAA CTAGAATTCG ACGAAATGCT 
GAAAAGGATT TTTGCAAGGA ATATGAAAAA CAAGTGAGAA ATGGAAGGCT TTTTTGTACA 
CGGGAGAGTG ATCCAGTCCG TGGCCCTGAC GGCAGGATGC ATGGCAACAA ATGTGCCCTG 
TGTGCTGAAA TTTTCAAGCA GCGTTTTTCA GAGGAAAACA GTAAAACAGA TCAAAATTTG 
GGAAAAGCTG AAGAAAAAAC TAAAGTTAAA AGAGAAATTG TGAAACTCTG CAGTCAATAT 
CAAAATCAGG CAAAGAATGG AATACTTTTC TGTACCAGAG AAAATGACCC TATTCGTGGT 
CCAGATGGGA AAATGCATGG CAACTTGTGT TCCATGTGTC AAGCCTACTT CCAAGCAGAA 
AATGAAGAAA AGAAAAAGGC TGAAGCACGA GCTAGAAACA AAAGAGAATC TGGAAAAGCA 
ACCTCATATG CAGAGCTTTG CAGTGAATAT CGAAAGCTTG TGAGGAACGG AAAACTTGCT 
TGCACCAGAG AGAACGATCC TATCCAGGGC CCAGATGGGA AAGTGCATGG CAACACCTGC 
TCCATGTGTG AGGTCTTCTT CCAAGCAGAA GAAGAAGAAA AGAAAAAGAA GGAAGGTAAA 
TCAAGAAACA AAAGACAATC TAAGAGTACA GCTTCCTTTG AGGAGTTGTG TAGTGAATAC 
CGCAAATCCA GGAAAAACGG ACGGCTTTTT TGCACCAGAG AGAATGACCC CATCCAGGGC 
CCAGATGGAA AAATGCATGG CAACACCTGC TCCATGTGTG AGGCCTTCTT TCAACAAGAA 
GAAAGAGCAA GAGCAAAGGC TAAAAGAGAA GCTGCAAAGG AAATCTGCAG TGAATTTCGG 
GACCAAGTGA GGAATGGAAC ACTTATATGC ACCAGGGAGC ATAATCCTGT CCGTGGCCCA 
GATGGCAAAA TGCATGGAAA CAAGTGTGCC ATGTGTGCCA GTGTGTTCAA ACTTGAAGAA 
GAAGAGAAGA AAAATGATAA AGAAGAAAAA GGGAAAGTCG AGGCTGAAAA AGTTAAGAGA 
GAAGCAGTTC AGGAGCTGTG CAGTGAATAT CGTCATTATG TGAGGAATGG ACGACTCCCC 
TGTACCAGAG AGAATGATCC TATTGAGGGT CTAGATGGGA AAATCCACGG CAACACCTGC 
TCCATGTGTG AAGCCTTCTT CCAGCAAGAA GCAAAAGAAA AAGAAAGAGC TGAACCCAGA 
GCAAAAGTCA AAAGAGAAGC TGAAAAGGAG ACATGCGATG AATTTCGGAG ACTTTTGCAA 
AATGGAAAAC TTTTCTGCAC AAGAGAAAAT GATCCTGTGC GTGGCCCAGA TGGCAAGACC 
CATGGCAACA AGTGTGCCAT GTGTAAGGCA GTCTTCCAGA AAGAAAATGA GGAAAGAAAG 
AGGAAAGAAG AGGAAGATCA GAGAAATGCT GCAGGACATG GTTCCAGTGG TGGTGGAGGA 
GGAAACACTC AGGACGAATG TGCTGAGTAT CGGGAACAAA TGAAAAATGG AAGACTCAGC 
TGTACTCGGG AGAGTGATCC TGTACGTGAT GCTGATGGCA AATCGTACAA CAATCAGTGT 
ACCATGTGTA AAGCAAAATT GGAAAGAGAA GCAGAGAGAA AAAATGAGTA TTCTCGCTCC 
AGATCAAATG GGACTGGATC AGAATCAGGG AAGGATACAT GTGATGAGTT TAGAAGCCAA 
ATGAAAAATG GAAAACTCAT CTGCACTCGA GAAAGTGACC CTGTCCGGGG TCCAGATGGC 
AAGACACATG GCAATAAGTG TACTATGTGT AAGGAAAAAC TGGAAAGGGA AGCAGCTGAA 
AAAAAAAAGA AAGAGGATGA AGACAGGAGC AATACAGGAG AAAGGAGCAA TACAGGAGAA 
AGGAGCAATG ACAAAGAGGA TCTGTGTCGT GAATTTCGAA GCATGCAGAG AAATGGAAAG 
CTTATCTGCA CCAGAGAAAA TAACCCTGTT CGAGGCCCAT ATGGCAAGAT GCACATCAAT 
AAATGTGCTA TGTGTCAGAG CATCTTTGAT CGAGAAGCTA ATGAAAGAAA AAAGAAAGAT 
GAAGAGAAAT CAAGTAGCAA GCCCTCAAAT AATGCAAAGG TTATTTATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPINK5 ( NM_001127699.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001121171.1 Homo sapiens serine peptidase inhibitor Kazal type 5 (SPINK5), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu31774
Clone ID Related Accession (Same CDS sequence)	NM_001127699.1 , NM_001127699.2
Accession Version	NM_001127699.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2751bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-01
Organism	Homo sapiens(human)
Product	serine protease inhibitor Kazal-type 5 isoform c preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ149929.1, AK307588.1, AK307648.1, AK025197.1 and AC008722.6. On Jun 2, 2019 this sequence version replaced NM_001127699.1. Transcript Variant: This variant (3, also known as SPINK5sh) differs in the 3' UTR and lacks several exons in the 3' coding region, compared to variant 1. The resulting protein (isoform c, also known as the LEKTIsh or short isoform) has a distinct C-terminus and is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ149929.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAAGATAG CCACAGTGTC AGTGCTTCTG CCCTTGGCTC TTTGCCTCAT ACAAGATGCT 
GCCAGTAAGA ATGAAGATCA GGAAATGTGC CATGAATTTC AGGCATTTAT GAAAAATGGA 
AAACTGTTCT GTCCCCAGGA TAAGAAATTT TTTCAAAGTC TTGATGGAAT AATGTTCATC 
AATAAATGTG CCACGTGCAA AATGATACTG GAAAAAGAAG CAAAATCACA GAAGAGGGCC 
AGGCATTTAG CAAGAGCTCC CAAGGCTACT GCCCCAACAG AGCTGAATTG TGATGATTTT 
AAAAAAGGAG AAAGAGATGG GGATTTTATC TGTCCTGATT ATTATGAAGC TGTTTGTGGC 
ACAGATGGGA AAACATATGA CAACAGATGT GCACTGTGTG CTGAGAATGC GAAAACCGGG 
TCCCAAATTG GTGTAAAAAG TGAAGGGGAA TGTAAGAGCA GTAATCCAGA GCAGGATGTA 
TGCAGTGCTT TTCGGCCCTT TGTTAGAGAT GGAAGACTTG GATGCACAAG GGAAAATGAT 
CCTGTTCTTG GTCCTGATGG GAAGACGCAT GGCAATAAGT GTGCAATGTG TGCTGAGCTG 
TTTTTAAAAG AAGCTGAAAA TGCCAAGCGA GAGGGTGAAA CTAGAATTCG ACGAAATGCT 
GAAAAGGATT TTTGCAAGGA ATATGAAAAA CAAGTGAGAA ATGGAAGGCT TTTTTGTACA 
CGGGAGAGTG ATCCAGTCCG TGGCCCTGAC GGCAGGATGC ATGGCAACAA ATGTGCCCTG 
TGTGCTGAAA TTTTCAAGCA GCGTTTTTCA GAGGAAAACA GTAAAACAGA TCAAAATTTG 
GGAAAAGCTG AAGAAAAAAC TAAAGTTAAA AGAGAAATTG TGAAACTCTG CAGTCAATAT 
CAAAATCAGG CAAAGAATGG AATACTTTTC TGTACCAGAG AAAATGACCC TATTCGTGGT 
CCAGATGGGA AAATGCATGG CAACTTGTGT TCCATGTGTC AAGCCTACTT CCAAGCAGAA 
AATGAAGAAA AGAAAAAGGC TGAAGCACGA GCTAGAAACA AAAGAGAATC TGGAAAAGCA 
ACCTCATATG CAGAGCTTTG CAGTGAATAT CGAAAGCTTG TGAGGAACGG AAAACTTGCT 
TGCACCAGAG AGAACGATCC TATCCAGGGC CCAGATGGGA AAGTGCATGG CAACACCTGC 
TCCATGTGTG AGGTCTTCTT CCAAGCAGAA GAAGAAGAAA AGAAAAAGAA GGAAGGTAAA 
TCAAGAAACA AAAGACAATC TAAGAGTACA GCTTCCTTTG AGGAGTTGTG TAGTGAATAC 
CGCAAATCCA GGAAAAACGG ACGGCTTTTT TGCACCAGAG AGAATGACCC CATCCAGGGC 
CCAGATGGAA AAATGCATGG CAACACCTGC TCCATGTGTG AGGCCTTCTT TCAACAAGAA 
GAAAGAGCAA GAGCAAAGGC TAAAAGAGAA GCTGCAAAGG AAATCTGCAG TGAATTTCGG 
GACCAAGTGA GGAATGGAAC ACTTATATGC ACCAGGGAGC ATAATCCTGT CCGTGGCCCA 
GATGGCAAAA TGCATGGAAA CAAGTGTGCC ATGTGTGCCA GTGTGTTCAA ACTTGAAGAA 
GAAGAGAAGA AAAATGATAA AGAAGAAAAA GGGAAAGTCG AGGCTGAAAA AGTTAAGAGA 
GAAGCAGTTC AGGAGCTGTG CAGTGAATAT CGTCATTATG TGAGGAATGG ACGACTCCCC 
TGTACCAGAG AGAATGATCC TATTGAGGGT CTAGATGGGA AAATCCACGG CAACACCTGC 
TCCATGTGTG AAGCCTTCTT CCAGCAAGAA GCAAAAGAAA AAGAAAGAGC TGAACCCAGA 
GCAAAAGTCA AAAGAGAAGC TGAAAAGGAG ACATGCGATG AATTTCGGAG ACTTTTGCAA 
AATGGAAAAC TTTTCTGCAC AAGAGAAAAT GATCCTGTGC GTGGCCCAGA TGGCAAGACC 
CATGGCAACA AGTGTGCCAT GTGTAAGGCA GTCTTCCAGA AAGAAAATGA GGAAAGAAAG 
AGGAAAGAAG AGGAAGATCA GAGAAATGCT GCAGGACATG GTTCCAGTGG TGGTGGAGGA 
GGAAACACTC AGGACGAATG TGCTGAGTAT CGGGAACAAA TGAAAAATGG AAGACTCAGC 
TGTACTCGGG AGAGTGATCC TGTACGTGAT GCTGATGGCA AATCGTACAA CAATCAGTGT 
ACCATGTGTA AAGCAAAATT GGAAAGAGAA GCAGAGAGAA AAAATGAGTA TTCTCGCTCC 
AGATCAAATG GGACTGGATC AGAATCAGGG AAGGATACAT GTGATGAGTT TAGAAGCCAA 
ATGAAAAATG GAAAACTCAT CTGCACTCGA GAAAGTGACC CTGTCCGGGG TCCAGATGGC 
AAGACACATG GCAATAAGTG TACTATGTGT AAGGAAAAAC TGGAAAGGGA AGCAGCTGAA 
AAAAAAAAGA AAGAGGATGA AGACAGGAGC AATACAGGAG AAAGGAGCAA TACAGGAGAA 
AGGAGCAATG ACAAAGAGGA TCTGTGTCGT GAATTTCGAA GCATGCAGAG AAATGGAAAG 
CTTATCTGCA CCAGAGAAAA TAACCCTGTT CGAGGCCCAT ATGGCAAGAT GCACATCAAT 
AAATGTGCTA TGTGTCAGAG CATCTTTGAT CGAGAAGCTA ATGAAAGAAA AAAGAAAGAT 
GAAGAGAAAT CAAGTAGCAA GCCCTCAAAT AATGCAAAGG TTATTTATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121171.1
CDS	66..2816
Translation	MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNAKVIY

Target ORF information:

RefSeq Version	NM_001127699.2
Organism	Homo sapiens(human)
Definition	Homo sapiens serine peptidase inhibitor Kazal type 5 (SPINK5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127699.2

ORF Insert Sequence:

ATGAAGATAG CCACAGTGTC AGTGCTTCTG CCCTTGGCTC TTTGCCTCAT ACAAGATGCT 
GCCAGTAAGA ATGAAGATCA GGAAATGTGC CATGAATTTC AGGCATTTAT GAAAAATGGA 
AAACTGTTCT GTCCCCAGGA TAAGAAATTT TTTCAAAGTC TTGATGGAAT AATGTTCATC 
AATAAATGTG CCACGTGCAA AATGATACTG GAAAAAGAAG CAAAATCACA GAAGAGGGCC 
AGGCATTTAG CAAGAGCTCC CAAGGCTACT GCCCCAACAG AGCTGAATTG TGATGATTTT 
AAAAAAGGAG AAAGAGATGG GGATTTTATC TGTCCTGATT ATTATGAAGC TGTTTGTGGC 
ACAGATGGGA AAACATATGA CAACAGATGT GCACTGTGTG CTGAGAATGC GAAAACCGGG 
TCCCAAATTG GTGTAAAAAG TGAAGGGGAA TGTAAGAGCA GTAATCCAGA GCAGGATGTA 
TGCAGTGCTT TTCGGCCCTT TGTTAGAGAT GGAAGACTTG GATGCACAAG GGAAAATGAT 
CCTGTTCTTG GTCCTGATGG GAAGACGCAT GGCAATAAGT GTGCAATGTG TGCTGAGCTG 
TTTTTAAAAG AAGCTGAAAA TGCCAAGCGA GAGGGTGAAA CTAGAATTCG ACGAAATGCT 
GAAAAGGATT TTTGCAAGGA ATATGAAAAA CAAGTGAGAA ATGGAAGGCT TTTTTGTACA 
CGGGAGAGTG ATCCAGTCCG TGGCCCTGAC GGCAGGATGC ATGGCAACAA ATGTGCCCTG 
TGTGCTGAAA TTTTCAAGCA GCGTTTTTCA GAGGAAAACA GTAAAACAGA TCAAAATTTG 
GGAAAAGCTG AAGAAAAAAC TAAAGTTAAA AGAGAAATTG TGAAACTCTG CAGTCAATAT 
CAAAATCAGG CAAAGAATGG AATACTTTTC TGTACCAGAG AAAATGACCC TATTCGTGGT 
CCAGATGGGA AAATGCATGG CAACTTGTGT TCCATGTGTC AAGCCTACTT CCAAGCAGAA 
AATGAAGAAA AGAAAAAGGC TGAAGCACGA GCTAGAAACA AAAGAGAATC TGGAAAAGCA 
ACCTCATATG CAGAGCTTTG CAGTGAATAT CGAAAGCTTG TGAGGAACGG AAAACTTGCT 
TGCACCAGAG AGAACGATCC TATCCAGGGC CCAGATGGGA AAGTGCATGG CAACACCTGC 
TCCATGTGTG AGGTCTTCTT CCAAGCAGAA GAAGAAGAAA AGAAAAAGAA GGAAGGTAAA 
TCAAGAAACA AAAGACAATC TAAGAGTACA GCTTCCTTTG AGGAGTTGTG TAGTGAATAC 
CGCAAATCCA GGAAAAACGG ACGGCTTTTT TGCACCAGAG AGAATGACCC CATCCAGGGC 
CCAGATGGAA AAATGCATGG CAACACCTGC TCCATGTGTG AGGCCTTCTT TCAACAAGAA 
GAAAGAGCAA GAGCAAAGGC TAAAAGAGAA GCTGCAAAGG AAATCTGCAG TGAATTTCGG 
GACCAAGTGA GGAATGGAAC ACTTATATGC ACCAGGGAGC ATAATCCTGT CCGTGGCCCA 
GATGGCAAAA TGCATGGAAA CAAGTGTGCC ATGTGTGCCA GTGTGTTCAA ACTTGAAGAA 
GAAGAGAAGA AAAATGATAA AGAAGAAAAA GGGAAAGTCG AGGCTGAAAA AGTTAAGAGA 
GAAGCAGTTC AGGAGCTGTG CAGTGAATAT CGTCATTATG TGAGGAATGG ACGACTCCCC 
TGTACCAGAG AGAATGATCC TATTGAGGGT CTAGATGGGA AAATCCACGG CAACACCTGC 
TCCATGTGTG AAGCCTTCTT CCAGCAAGAA GCAAAAGAAA AAGAAAGAGC TGAACCCAGA 
GCAAAAGTCA AAAGAGAAGC TGAAAAGGAG ACATGCGATG AATTTCGGAG ACTTTTGCAA 
AATGGAAAAC TTTTCTGCAC AAGAGAAAAT GATCCTGTGC GTGGCCCAGA TGGCAAGACC 
CATGGCAACA AGTGTGCCAT GTGTAAGGCA GTCTTCCAGA AAGAAAATGA GGAAAGAAAG 
AGGAAAGAAG AGGAAGATCA GAGAAATGCT GCAGGACATG GTTCCAGTGG TGGTGGAGGA 
GGAAACACTC AGGACGAATG TGCTGAGTAT CGGGAACAAA TGAAAAATGG AAGACTCAGC 
TGTACTCGGG AGAGTGATCC TGTACGTGAT GCTGATGGCA AATCGTACAA CAATCAGTGT 
ACCATGTGTA AAGCAAAATT GGAAAGAGAA GCAGAGAGAA AAAATGAGTA TTCTCGCTCC 
AGATCAAATG GGACTGGATC AGAATCAGGG AAGGATACAT GTGATGAGTT TAGAAGCCAA 
ATGAAAAATG GAAAACTCAT CTGCACTCGA GAAAGTGACC CTGTCCGGGG TCCAGATGGC 
AAGACACATG GCAATAAGTG TACTATGTGT AAGGAAAAAC TGGAAAGGGA AGCAGCTGAA 
AAAAAAAAGA AAGAGGATGA AGACAGGAGC AATACAGGAG AAAGGAGCAA TACAGGAGAA 
AGGAGCAATG ACAAAGAGGA TCTGTGTCGT GAATTTCGAA GCATGCAGAG AAATGGAAAG 
CTTATCTGCA CCAGAGAAAA TAACCCTGTT CGAGGCCCAT ATGGCAAGAT GCACATCAAT 
AAATGTGCTA TGTGTCAGAG CATCTTTGAT CGAGAAGCTA ATGAAAGAAA AAAGAAAGAT 
GAAGAGAAAT CAAGTAGCAA GCCCTCAAAT AATGCAAAGG TTATTTATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPINK5 ( NM_001127698.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001121170.1 Homo sapiens serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 1, mRNA.

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CloneID	OHu31833
Clone ID Related Accession (Same CDS sequence)	NM_001127698.1 , NM_001127698.2
Accession Version	NM_001127698.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3285bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	serine protease inhibitor Kazal-type 5 isoform a preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ149928.1, AK307588.1, AK307648.1, AK025197.1, BI256857.1, AI341060.1 and DR421881.1. Transcript Variant: This variant (1, also known as SPINK5l) represents the longest transcript and encodes the longest isoform (a, also known as the LEKTIl or long isoform). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ149928.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAAGATAG CCACAGTGTC AGTGCTTCTG CCCTTGGCTC TTTGCCTCAT ACAAGATGCT 
GCCAGTAAGA ATGAAGATCA GGAAATGTGC CATGAATTTC AGGCATTTAT GAAAAATGGA 
AAACTGTTCT GTCCCCAGGA TAAGAAATTT TTTCAAAGTC TTGATGGAAT AATGTTCATC 
AATAAATGTG CCACGTGCAA AATGATACTG GAAAAAGAAG CAAAATCACA GAAGAGGGCC 
AGGCATTTAG CAAGAGCTCC CAAGGCTACT GCCCCAACAG AGCTGAATTG TGATGATTTT 
AAAAAAGGAG AAAGAGATGG GGATTTTATC TGTCCTGATT ATTATGAAGC TGTTTGTGGC 
ACAGATGGGA AAACATATGA CAACAGATGT GCACTGTGTG CTGAGAATGC GAAAACCGGG 
TCCCAAATTG GTGTAAAAAG TGAAGGGGAA TGTAAGAGCA GTAATCCAGA GCAGGATGTA 
TGCAGTGCTT TTCGGCCCTT TGTTAGAGAT GGAAGACTTG GATGCACAAG GGAAAATGAT 
CCTGTTCTTG GTCCTGATGG GAAGACGCAT GGCAATAAGT GTGCAATGTG TGCTGAGCTG 
TTTTTAAAAG AAGCTGAAAA TGCCAAGCGA GAGGGTGAAA CTAGAATTCG ACGAAATGCT 
GAAAAGGATT TTTGCAAGGA ATATGAAAAA CAAGTGAGAA ATGGAAGGCT TTTTTGTACA 
CGGGAGAGTG ATCCAGTCCG TGGCCCTGAC GGCAGGATGC ATGGCAACAA ATGTGCCCTG 
TGTGCTGAAA TTTTCAAGCA GCGTTTTTCA GAGGAAAACA GTAAAACAGA TCAAAATTTG 
GGAAAAGCTG AAGAAAAAAC TAAAGTTAAA AGAGAAATTG TGAAACTCTG CAGTCAATAT 
CAAAATCAGG CAAAGAATGG AATACTTTTC TGTACCAGAG AAAATGACCC TATTCGTGGT 
CCAGATGGGA AAATGCATGG CAACTTGTGT TCCATGTGTC AAGCCTACTT CCAAGCAGAA 
AATGAAGAAA AGAAAAAGGC TGAAGCACGA GCTAGAAACA AAAGAGAATC TGGAAAAGCA 
ACCTCATATG CAGAGCTTTG CAGTGAATAT CGAAAGCTTG TGAGGAACGG AAAACTTGCT 
TGCACCAGAG AGAACGATCC TATCCAGGGC CCAGATGGGA AAGTGCATGG CAACACCTGC 
TCCATGTGTG AGGTCTTCTT CCAAGCAGAA GAAGAAGAAA AGAAAAAGAA GGAAGGTAAA 
TCAAGAAACA AAAGACAATC TAAGAGTACA GCTTCCTTTG AGGAGTTGTG TAGTGAATAC 
CGCAAATCCA GGAAAAACGG ACGGCTTTTT TGCACCAGAG AGAATGACCC CATCCAGGGC 
CCAGATGGAA AAATGCATGG CAACACCTGC TCCATGTGTG AGGCCTTCTT TCAACAAGAA 
GAAAGAGCAA GAGCAAAGGC TAAAAGAGAA GCTGCAAAGG AAATCTGCAG TGAATTTCGG 
GACCAAGTGA GGAATGGAAC ACTTATATGC ACCAGGGAGC ATAATCCTGT CCGTGGCCCA 
GATGGCAAAA TGCATGGAAA CAAGTGTGCC ATGTGTGCCA GTGTGTTCAA ACTTGAAGAA 
GAAGAGAAGA AAAATGATAA AGAAGAAAAA GGGAAAGTCG AGGCTGAAAA AGTTAAGAGA 
GAAGCAGTTC AGGAGCTGTG CAGTGAATAT CGTCATTATG TGAGGAATGG ACGACTCCCC 
TGTACCAGAG AGAATGATCC TATTGAGGGT CTAGATGGGA AAATCCACGG CAACACCTGC 
TCCATGTGTG AAGCCTTCTT CCAGCAAGAA GCAAAAGAAA AAGAAAGAGC TGAACCCAGA 
GCAAAAGTCA AAAGAGAAGC TGAAAAGGAG ACATGCGATG AATTTCGGAG ACTTTTGCAA 
AATGGAAAAC TTTTCTGCAC AAGAGAAAAT GATCCTGTGC GTGGCCCAGA TGGCAAGACC 
CATGGCAACA AGTGTGCCAT GTGTAAGGCA GTCTTCCAGA AAGAAAATGA GGAAAGAAAG 
AGGAAAGAAG AGGAAGATCA GAGAAATGCT GCAGGACATG GTTCCAGTGG TGGTGGAGGA 
GGAAACACTC AGGACGAATG TGCTGAGTAT CGGGAACAAA TGAAAAATGG AAGACTCAGC 
TGTACTCGGG AGAGTGATCC TGTACGTGAT GCTGATGGCA AATCGTACAA CAATCAGTGT 
ACCATGTGTA AAGCAAAATT GGAAAGAGAA GCAGAGAGAA AAAATGAGTA TTCTCGCTCC 
AGATCAAATG GGACTGGATC AGAATCAGGG AAGGATACAT GTGATGAGTT TAGAAGCCAA 
ATGAAAAATG GAAAACTCAT CTGCACTCGA GAAAGTGACC CTGTCCGGGG TCCAGATGGC 
AAGACACATG GCAATAAGTG TACTATGTGT AAGGAAAAAC TGGAAAGGGA AGCAGCTGAA 
AAAAAAAAGA AAGAGGATGA AGACAGGAGC AATACAGGAG AAAGGAGCAA TACAGGAGAA 
AGGAGCAATG ACAAAGAGGA TCTGTGTCGT GAATTTCGAA GCATGCAGAG AAATGGAAAG 
CTTATCTGCA CCAGAGAAAA TAACCCTGTT CGAGGCCCAT ATGGCAAGAT GCACATCAAT 
AAATGTGCTA TGTGTCAGAG CATCTTTGAT CGAGAAGCTA ATGAAAGAAA AAAGAAAGAT 
GAAGAGAAAT CAAGTAGCAA GCCCTCAAAT AATGCAAAGG ACCAGTGCAG ACAGGTTCAG 
AATGAAGCGG AGGATGCAAA ATTTAGACAA CCTGGGCGTT CCTTGGCCTC TGTTGCCAGG 
ATGAGTACAG ATGAGTGCAG TGAATTTCGA AACTATATAA GGAACAATGA ACTCATCTGC 
CCTAGAGAGA ATGACCCAGT GCACGGTGCT GATGGAAAGT TCTATACAAA CAAGTGCTAC 
ATGTGCAGAG CTGTCTTTCT AACAGAAGCT TTGGAAAGGG CAAAGCTTCA AGAAAAGCCA 
TCCCATGTTA GAGCTTCTCA AGAGGAAGAC AGCCCAGACT CTTTCAGTTC TCTGGATTCT 
GAGATGTGCA AAGACTACCG AGTATTGCCC AGGATAGGTT ATCTTTGTCC AAAGGATTTA 
AAGCCTGTCT GTGGTGACGA TGGCCAAACC TACAACAATC CTTGCATGCT CTGTCATGAA 
AACCTGATAC GCCAAACAAA TACACACATC CGCAGTACAG GGAAGTGTGA GGAGAGCAGC 
ACCCCAGGAA CCACCGCAGC CAGCATGCCC CCGTCTGACG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121170.1
CDS	74..3358
Translation	MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNAKDQCRQVQNEAEDAKFRQPGRSLASVARMSTDECSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAVFLTEALERAKLQEKPSHVRASQEEDSPDSFSSLDSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKCEESSTPGTTAASMPPSDE

Target ORF information:

RefSeq Version	NM_001127698.1
Organism	Homo sapiens(human)
Definition	Homo sapiens serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127698.1

ORF Insert Sequence:

ATGAAGATAG CCACAGTGTC AGTGCTTCTG CCCTTGGCTC TTTGCCTCAT ACAAGATGCT 
GCCAGTAAGA ATGAAGATCA GGAAATGTGC CATGAATTTC AGGCATTTAT GAAAAATGGA 
AAACTGTTCT GTCCCCAGGA TAAGAAATTT TTTCAAAGTC TTGATGGAAT AATGTTCATC 
AATAAATGTG CCACGTGCAA AATGATACTG GAAAAAGAAG CAAAATCACA GAAGAGGGCC 
AGGCATTTAG CAAGAGCTCC CAAGGCTACT GCCCCAACAG AGCTGAATTG TGATGATTTT 
AAAAAAGGAG AAAGAGATGG GGATTTTATC TGTCCTGATT ATTATGAAGC TGTTTGTGGC 
ACAGATGGGA AAACATATGA CAACAGATGT GCACTGTGTG CTGAGAATGC GAAAACCGGG 
TCCCAAATTG GTGTAAAAAG TGAAGGGGAA TGTAAGAGCA GTAATCCAGA GCAGGATGTA 
TGCAGTGCTT TTCGGCCCTT TGTTAGAGAT GGAAGACTTG GATGCACAAG GGAAAATGAT 
CCTGTTCTTG GTCCTGATGG GAAGACGCAT GGCAATAAGT GTGCAATGTG TGCTGAGCTG 
TTTTTAAAAG AAGCTGAAAA TGCCAAGCGA GAGGGTGAAA CTAGAATTCG ACGAAATGCT 
GAAAAGGATT TTTGCAAGGA ATATGAAAAA CAAGTGAGAA ATGGAAGGCT TTTTTGTACA 
CGGGAGAGTG ATCCAGTCCG TGGCCCTGAC GGCAGGATGC ATGGCAACAA ATGTGCCCTG 
TGTGCTGAAA TTTTCAAGCA GCGTTTTTCA GAGGAAAACA GTAAAACAGA TCAAAATTTG 
GGAAAAGCTG AAGAAAAAAC TAAAGTTAAA AGAGAAATTG TGAAACTCTG CAGTCAATAT 
CAAAATCAGG CAAAGAATGG AATACTTTTC TGTACCAGAG AAAATGACCC TATTCGTGGT 
CCAGATGGGA AAATGCATGG CAACTTGTGT TCCATGTGTC AAGCCTACTT CCAAGCAGAA 
AATGAAGAAA AGAAAAAGGC TGAAGCACGA GCTAGAAACA AAAGAGAATC TGGAAAAGCA 
ACCTCATATG CAGAGCTTTG CAGTGAATAT CGAAAGCTTG TGAGGAACGG AAAACTTGCT 
TGCACCAGAG AGAACGATCC TATCCAGGGC CCAGATGGGA AAGTGCATGG CAACACCTGC 
TCCATGTGTG AGGTCTTCTT CCAAGCAGAA GAAGAAGAAA AGAAAAAGAA GGAAGGTAAA 
TCAAGAAACA AAAGACAATC TAAGAGTACA GCTTCCTTTG AGGAGTTGTG TAGTGAATAC 
CGCAAATCCA GGAAAAACGG ACGGCTTTTT TGCACCAGAG AGAATGACCC CATCCAGGGC 
CCAGATGGAA AAATGCATGG CAACACCTGC TCCATGTGTG AGGCCTTCTT TCAACAAGAA 
GAAAGAGCAA GAGCAAAGGC TAAAAGAGAA GCTGCAAAGG AAATCTGCAG TGAATTTCGG 
GACCAAGTGA GGAATGGAAC ACTTATATGC ACCAGGGAGC ATAATCCTGT CCGTGGCCCA 
GATGGCAAAA TGCATGGAAA CAAGTGTGCC ATGTGTGCCA GTGTGTTCAA ACTTGAAGAA 
GAAGAGAAGA AAAATGATAA AGAAGAAAAA GGGAAAGTCG AGGCTGAAAA AGTTAAGAGA 
GAAGCAGTTC AGGAGCTGTG CAGTGAATAT CGTCATTATG TGAGGAATGG ACGACTCCCC 
TGTACCAGAG AGAATGATCC TATTGAGGGT CTAGATGGGA AAATCCACGG CAACACCTGC 
TCCATGTGTG AAGCCTTCTT CCAGCAAGAA GCAAAAGAAA AAGAAAGAGC TGAACCCAGA 
GCAAAAGTCA AAAGAGAAGC TGAAAAGGAG ACATGCGATG AATTTCGGAG ACTTTTGCAA 
AATGGAAAAC TTTTCTGCAC AAGAGAAAAT GATCCTGTGC GTGGCCCAGA TGGCAAGACC 
CATGGCAACA AGTGTGCCAT GTGTAAGGCA GTCTTCCAGA AAGAAAATGA GGAAAGAAAG 
AGGAAAGAAG AGGAAGATCA GAGAAATGCT GCAGGACATG GTTCCAGTGG TGGTGGAGGA 
GGAAACACTC AGGACGAATG TGCTGAGTAT CGGGAACAAA TGAAAAATGG AAGACTCAGC 
TGTACTCGGG AGAGTGATCC TGTACGTGAT GCTGATGGCA AATCGTACAA CAATCAGTGT 
ACCATGTGTA AAGCAAAATT GGAAAGAGAA GCAGAGAGAA AAAATGAGTA TTCTCGCTCC 
AGATCAAATG GGACTGGATC AGAATCAGGG AAGGATACAT GTGATGAGTT TAGAAGCCAA 
ATGAAAAATG GAAAACTCAT CTGCACTCGA GAAAGTGACC CTGTCCGGGG TCCAGATGGC 
AAGACACATG GCAATAAGTG TACTATGTGT AAGGAAAAAC TGGAAAGGGA AGCAGCTGAA 
AAAAAAAAGA AAGAGGATGA AGACAGGAGC AATACAGGAG AAAGGAGCAA TACAGGAGAA 
AGGAGCAATG ACAAAGAGGA TCTGTGTCGT GAATTTCGAA GCATGCAGAG AAATGGAAAG 
CTTATCTGCA CCAGAGAAAA TAACCCTGTT CGAGGCCCAT ATGGCAAGAT GCACATCAAT 
AAATGTGCTA TGTGTCAGAG CATCTTTGAT CGAGAAGCTA ATGAAAGAAA AAAGAAAGAT 
GAAGAGAAAT CAAGTAGCAA GCCCTCAAAT AATGCAAAGG ACCAGTGCAG ACAGGTTCAG 
AATGAAGCGG AGGATGCAAA ATTTAGACAA CCTGGGCGTT CCTTGGCCTC TGTTGCCAGG 
ATGAGTACAG ATGAGTGCAG TGAATTTCGA AACTATATAA GGAACAATGA ACTCATCTGC 
CCTAGAGAGA ATGACCCAGT GCACGGTGCT GATGGAAAGT TCTATACAAA CAAGTGCTAC 
ATGTGCAGAG CTGTCTTTCT AACAGAAGCT TTGGAAAGGG CAAAGCTTCA AGAAAAGCCA 
TCCCATGTTA GAGCTTCTCA AGAGGAAGAC AGCCCAGACT CTTTCAGTTC TCTGGATTCT 
GAGATGTGCA AAGACTACCG AGTATTGCCC AGGATAGGTT ATCTTTGTCC AAAGGATTTA 
AAGCCTGTCT GTGGTGACGA TGGCCAAACC TACAACAATC CTTGCATGCT CTGTCATGAA 
AACCTGATAC GCCAAACAAA TACACACATC CGCAGTACAG GGAAGTGTGA GGAGAGCAGC 
ACCCCAGGAA CCACCGCAGC CAGCATGCCC CCGTCTGACG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPINK5 ( XM_011537551.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011535853.1 Homo sapiens serine peptidase inhibitor Kazal type 5 (SPINK5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu64572
Clone ID Related Accession (Same CDS sequence)	XM_011537551.2
Accession Version	XM_011537551.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3201bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	serine protease inhibitor Kazal-type 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011537551.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCCATG AATTTCAGGC ATTTATGAAA AATGGAAAAC TGTTCTGTCC CCAGGATAAG 
AAATTTTTTC AAAGTCTTGA TGGAATAATG TTCATCAATA AATGTGCCAC GTGCAAAATG 
ATACTGGAAA AAGAAGCAAA ATCACAGAAG AGGGCCAGGC ATTTAGCAAG AGCTCCCAAG 
GCTACTGCCC CAACAGAGCT GAATTGTGAT GATTTTAAAA AAGGAGAAAG AGATGGGGAT 
TTTATCTGTC CTGATTATTA TGAAGCTGTT TGTGGCACAG ATGGGAAAAC ATATGACAAC 
AGATGTGCAC TGTGTGCTGA GAATGCGAAA ACCGGGTCCC AAATTGGTGT AAAAAGTGAA 
GGGGAATGTA AGAGCAGTAA TCCAGAGCAG GATGTATGCA GTGCTTTTCG GCCCTTTGTT 
AGAGATGGAA GACTTGGATG CACAAGGGAA AATGATCCTG TTCTTGGTCC TGATGGGAAG 
ACGCATGGCA ATAAGTGTGC AATGTGTGCT GAGCTGTTTT TAAAAGAAGC TGAAAATGCC 
AAGCGAGAGG GTGAAACTAG AATTCGACGA AATGCTGAAA AGGATTTTTG CAAGGAATAT 
GAAAAACAAG TGAGAAATGG AAGGCTTTTT TGTACACGGG AGAGTGATCC AGTCCGTGGC 
CCTGACGGCA GGATGCATGG CAACAAATGT GCCCTGTGTG CTGAAATTTT CAAGCAGCGT 
TTTTCAGAGG AAAACAGTAA AACAGATCAA AATTTGGGAA AAGCTGAAGA AAAAACTAAA 
GTTAAAAGAG AAATTGTGAA ACTCTGCAGT CAATATCAAA ATCAGGCAAA GAATGGAATA 
CTTTTCTGTA CCAGAGAAAA TGACCCTATT CGTGGTCCAG ATGGGAAAAT GCATGGCAAC 
TTGTGTTCCA TGTGTCAAGC CTACTTCCAA GCAGAAAATG AAGAAAAGAA AAAGGCTGAA 
GCACGAGCTA GAAACAAAAG AGAATCTGGA AAAGCAACCT CATATGCAGA GCTTTGCAGT 
GAATATCGAA AGCTTGTGAG GAACGGAAAA CTTGCTTGCA CCAGAGAGAA CGATCCTATC 
CAGGGCCCAG ATGGGAAAGT GCATGGCAAC ACCTGCTCCA TGTGTGAGGT CTTCTTCCAA 
GCAGAAGAAG AAGAAAAGAA AAAGAAGGAA GGTAAATCAA GAAACAAAAG ACAATCTAAG 
AGTACAGCTT CCTTTGAGGA GTTGTGTAGT GAATACCGCA AATCCAGGAA AAACGGACGG 
CTTTTTTGCA CCAGAGAGAA TGACCCCATC CAGGGCCCAG ATGGAAAAAT GCATGGCAAC 
ACCTGCTCCA TGTGTGAGGC CTTCTTTCAA CAAGAAGAAA GAGCAAGAGC AAAGGCTAAA 
AGAGAAGCTG CAAAGGAAAT CTGCAGTGAA TTTCGGGACC AAGTGAGGAA TGGAACACTT 
ATATGCACCA GGGAGCATAA TCCTGTCCGT GGCCCAGATG GCAAAATGCA TGGAAACAAG 
TGTGCCATGT GTGCCAGTGT GTTCAAACTT GAAGAAGAAG AGAAGAAAAA TGATAAAGAA 
GAAAAAGGGA AAGTCGAGGC TGAAAAAGTT AAGAGAGAAG CAGTTCAGGA GCTGTGCAGT 
GAATATCGTC ATTATGTGAG GAATGGACGA CTCCCCTGTA CCAGAGAGAA TGATCCTATT 
GAGGGTCTAG ATGGGAAAAT CCACGGCAAC ACCTGCTCCA TGTGTGAAGC CTTCTTCCAG 
CAAGAAGCAA AAGAAAAAGA AAGAGCTGAA CCCAGAGCAA AAGTCAAAAG AGAAGCTGAA 
AAGGAGACAT GCGATGAATT TCGGAGACTT TTGCAAAATG GAAAACTTTT CTGCACAAGA 
GAAAATGATC CTGTGCGTGG CCCAGATGGC AAGACCCATG GCAACAAGTG TGCCATGTGT 
AAGGCAGTCT TCCAGAAAGA AAATGAGGAA AGAAAGAGGA AAGAAGAGGA AGATCAGAGA 
AATGCTGCAG GACATGGTTC CAGTGGTGGT GGAGGAGGAA ACACTCAGGA CGAATGTGCT 
GAGTATCGGG AACAAATGAA AAATGGAAGA CTCAGCTGTA CTCGGGAGAG TGATCCTGTA 
CGTGATGCTG ATGGCAAATC GTACAACAAT CAGTGTACCA TGTGTAAAGC AAAATTGGAA 
AGAGAAGCAG AGAGAAAAAA TGAGTATTCT CGCTCCAGAT CAAATGGGAC TGGATCAGAA 
TCAGGGAAGG ATACATGTGA TGAGTTTAGA AGCCAAATGA AAAATGGAAA ACTCATCTGC 
ACTCGAGAAA GTGACCCTGT CCGGGGTCCA GATGGCAAGA CACATGGCAA TAAGTGTACT 
ATGTGTAAGG AAAAACTGGA AAGGGAAGCA GCTGAAAAAA AAAAGAAAGA GGATGAAGAC 
AGGAGCAATA CAGGAGAAAG GAGCAATACA GGAGAAAGGA GCAATGACAA AGAGGATCTG 
TGTCGTGAAT TTCGAAGCAT GCAGAGAAAT GGAAAGCTTA TCTGCACCAG AGAAAATAAC 
CCTGTTCGAG GCCCATATGG CAAGATGCAC ATCAATAAAT GTGCTATGTG TCAGAGCATC 
TTTGATCGAG AAGCTAATGA AAGAAAAAAG AAAGATGAAG AGAAATCAAG TAGCAAGCCC 
TCAAATAATG CAAAGGACCA GTGCAGACAG GTTCAGAATG AAGCGGAGGA TGCAAAATTT 
AGACAACCTG GGCGTTCCTT GGCCTCTGTT GCCAGGATGA GTACAGATGA GTGCAGTGAA 
TTTCGAAACT ATATAAGGAA CAATGAACTC ATCTGCCCTA GAGAGAATGA CCCAGTGCAC 
GGTGCTGATG GAAAGTTCTA TACAAACAAG TGCTACATGT GCAGAGCTGT CTTTCTAACA 
GAAGCTTTGG AAAGGGCAAA GCTTCAAGAA AAGCCATCCC ATGTTAGAGC TTCTCAAGAG 
GAAGACAGCC CAGACTCTTT CAGTTCTCTG GATTCTGAGA TGTGCAAAGA CTACCGAGTA 
TTGCCCAGGA TAGGTTATCT TTGTCCAAAG GATTTAAAGC CTGTCTGTGG TGACGATGGC 
CAAACCTACA ACAATCCTTG CATGCTCTGT CATGAAAACC TGATACGCCA AACAAATACA 
CACATCCGCA GTACAGGGAA GTGTGAGGAG AGCAGCACCC CAGGAACCAC CGCAGCCAGC 
ATGCCCCCGT CTGACGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011535853.1
CDS	244..3444
Translation	MCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNAKDQCRQVQNEAEDAKFRQPGRSLASVARMSTDECSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAVFLTEALERAKLQEKPSHVRASQEEDSPDSFSSLDSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKCEESSTPGTTAASMPPSDE

Target ORF information:

RefSeq Version	XM_011537551.2
Organism	Homo sapiens(human)
Definition	Homo sapiens serine peptidase inhibitor Kazal type 5 (SPINK5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011537551.2

ORF Insert Sequence:

ATGTGCCATG AATTTCAGGC ATTTATGAAA AATGGAAAAC TGTTCTGTCC CCAGGATAAG 
AAATTTTTTC AAAGTCTTGA TGGAATAATG TTCATCAATA AATGTGCCAC GTGCAAAATG 
ATACTGGAAA AAGAAGCAAA ATCACAGAAG AGGGCCAGGC ATTTAGCAAG AGCTCCCAAG 
GCTACTGCCC CAACAGAGCT GAATTGTGAT GATTTTAAAA AAGGAGAAAG AGATGGGGAT 
TTTATCTGTC CTGATTATTA TGAAGCTGTT TGTGGCACAG ATGGGAAAAC ATATGACAAC 
AGATGTGCAC TGTGTGCTGA GAATGCGAAA ACCGGGTCCC AAATTGGTGT AAAAAGTGAA 
GGGGAATGTA AGAGCAGTAA TCCAGAGCAG GATGTATGCA GTGCTTTTCG GCCCTTTGTT 
AGAGATGGAA GACTTGGATG CACAAGGGAA AATGATCCTG TTCTTGGTCC TGATGGGAAG 
ACGCATGGCA ATAAGTGTGC AATGTGTGCT GAGCTGTTTT TAAAAGAAGC TGAAAATGCC 
AAGCGAGAGG GTGAAACTAG AATTCGACGA AATGCTGAAA AGGATTTTTG CAAGGAATAT 
GAAAAACAAG TGAGAAATGG AAGGCTTTTT TGTACACGGG AGAGTGATCC AGTCCGTGGC 
CCTGACGGCA GGATGCATGG CAACAAATGT GCCCTGTGTG CTGAAATTTT CAAGCAGCGT 
TTTTCAGAGG AAAACAGTAA AACAGATCAA AATTTGGGAA AAGCTGAAGA AAAAACTAAA 
GTTAAAAGAG AAATTGTGAA ACTCTGCAGT CAATATCAAA ATCAGGCAAA GAATGGAATA 
CTTTTCTGTA CCAGAGAAAA TGACCCTATT CGTGGTCCAG ATGGGAAAAT GCATGGCAAC 
TTGTGTTCCA TGTGTCAAGC CTACTTCCAA GCAGAAAATG AAGAAAAGAA AAAGGCTGAA 
GCACGAGCTA GAAACAAAAG AGAATCTGGA AAAGCAACCT CATATGCAGA GCTTTGCAGT 
GAATATCGAA AGCTTGTGAG GAACGGAAAA CTTGCTTGCA CCAGAGAGAA CGATCCTATC 
CAGGGCCCAG ATGGGAAAGT GCATGGCAAC ACCTGCTCCA TGTGTGAGGT CTTCTTCCAA 
GCAGAAGAAG AAGAAAAGAA AAAGAAGGAA GGTAAATCAA GAAACAAAAG ACAATCTAAG 
AGTACAGCTT CCTTTGAGGA GTTGTGTAGT GAATACCGCA AATCCAGGAA AAACGGACGG 
CTTTTTTGCA CCAGAGAGAA TGACCCCATC CAGGGCCCAG ATGGAAAAAT GCATGGCAAC 
ACCTGCTCCA TGTGTGAGGC CTTCTTTCAA CAAGAAGAAA GAGCAAGAGC AAAGGCTAAA 
AGAGAAGCTG CAAAGGAAAT CTGCAGTGAA TTTCGGGACC AAGTGAGGAA TGGAACACTT 
ATATGCACCA GGGAGCATAA TCCTGTCCGT GGCCCAGATG GCAAAATGCA TGGAAACAAG 
TGTGCCATGT GTGCCAGTGT GTTCAAACTT GAAGAAGAAG AGAAGAAAAA TGATAAAGAA 
GAAAAAGGGA AAGTCGAGGC TGAAAAAGTT AAGAGAGAAG CAGTTCAGGA GCTGTGCAGT 
GAATATCGTC ATTATGTGAG GAATGGACGA CTCCCCTGTA CCAGAGAGAA TGATCCTATT 
GAGGGTCTAG ATGGGAAAAT CCACGGCAAC ACCTGCTCCA TGTGTGAAGC CTTCTTCCAG 
CAAGAAGCAA AAGAAAAAGA AAGAGCTGAA CCCAGAGCAA AAGTCAAAAG AGAAGCTGAA 
AAGGAGACAT GCGATGAATT TCGGAGACTT TTGCAAAATG GAAAACTTTT CTGCACAAGA 
GAAAATGATC CTGTGCGTGG CCCAGATGGC AAGACCCATG GCAACAAGTG TGCCATGTGT 
AAGGCAGTCT TCCAGAAAGA AAATGAGGAA AGAAAGAGGA AAGAAGAGGA AGATCAGAGA 
AATGCTGCAG GACATGGTTC CAGTGGTGGT GGAGGAGGAA ACACTCAGGA CGAATGTGCT 
GAGTATCGGG AACAAATGAA AAATGGAAGA CTCAGCTGTA CTCGGGAGAG TGATCCTGTA 
CGTGATGCTG ATGGCAAATC GTACAACAAT CAGTGTACCA TGTGTAAAGC AAAATTGGAA 
AGAGAAGCAG AGAGAAAAAA TGAGTATTCT CGCTCCAGAT CAAATGGGAC TGGATCAGAA 
TCAGGGAAGG ATACATGTGA TGAGTTTAGA AGCCAAATGA AAAATGGAAA ACTCATCTGC 
ACTCGAGAAA GTGACCCTGT CCGGGGTCCA GATGGCAAGA CACATGGCAA TAAGTGTACT 
ATGTGTAAGG AAAAACTGGA AAGGGAAGCA GCTGAAAAAA AAAAGAAAGA GGATGAAGAC 
AGGAGCAATA CAGGAGAAAG GAGCAATACA GGAGAAAGGA GCAATGACAA AGAGGATCTG 
TGTCGTGAAT TTCGAAGCAT GCAGAGAAAT GGAAAGCTTA TCTGCACCAG AGAAAATAAC 
CCTGTTCGAG GCCCATATGG CAAGATGCAC ATCAATAAAT GTGCTATGTG TCAGAGCATC 
TTTGATCGAG AAGCTAATGA AAGAAAAAAG AAAGATGAAG AGAAATCAAG TAGCAAGCCC 
TCAAATAATG CAAAGGACCA GTGCAGACAG GTTCAGAATG AAGCGGAGGA TGCAAAATTT 
AGACAACCTG GGCGTTCCTT GGCCTCTGTT GCCAGGATGA GTACAGATGA GTGCAGTGAA 
TTTCGAAACT ATATAAGGAA CAATGAACTC ATCTGCCCTA GAGAGAATGA CCCAGTGCAC 
GGTGCTGATG GAAAGTTCTA TACAAACAAG TGCTACATGT GCAGAGCTGT CTTTCTAACA 
GAAGCTTTGG AAAGGGCAAA GCTTCAAGAA AAGCCATCCC ATGTTAGAGC TTCTCAAGAG 
GAAGACAGCC CAGACTCTTT CAGTTCTCTG GATTCTGAGA TGTGCAAAGA CTACCGAGTA 
TTGCCCAGGA TAGGTTATCT TTGTCCAAAG GATTTAAAGC CTGTCTGTGG TGACGATGGC 
CAAACCTACA ACAATCCTTG CATGCTCTGT CATGAAAACC TGATACGCCA AACAAATACA 
CACATCCGCA GTACAGGGAA GTGTGAGGAG AGCAGCACCC CAGGAACCAC CGCAGCCAGC 
ATGCCCCCGT CTGACGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SPINK5 is associated with early-onset and CHI3L1 with late-onset atopic dermatitis.
International journal of immunogenetics44(5)212-218(2017 Oct)
De?man K,Koro?ec P,Rupnik H,Rijavec M

The skin barrier function gene SPINK5 is associated with?challenge-proven IgE-mediated food allergy in infants.
Allergy72(9)1356-1364(2017 Sep)
Ashley SE,Tan HT,Vuillermin P,Dharmage SC,Tang MLK,Koplin J,Gurrin LC,Lowe A,Lodge C,Ponsonby AL,Molloy J,Martin P,Matheson MC,Saffery R,Allen KJ,Ellis JA,Martino D,,

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SPINK5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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