RABAC1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RABAC1
Entrez Gene ID	10567
Full Name	Rab acceptor 1
Synonyms	PRA1,PRAF1,YIP3
General protein information	Preferred Names Rab acceptor 1 Names prenylated Rab acceptor protein 1 PRA1 domain family 1 PRA1 family protein 1 Rab acceptor 1 (prenylated) prenylated Rab acceptor 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.2
Disorder MIM:	604925

mRNA and Protein(s)

mRNA	Protein	Name
NM_006423.2	NP_006414.2	prenylated Rab acceptor protein 1
NM_006423.3	NP_006414.2	prenylated Rab acceptor protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	RABAC1	NP_006414.2
	RABAC1	XP_001104030.1
Canis lupus familiaris (dog)	RABAC1	NP_001003014.1
Mus musculus (house mouse)	Rabac1	NP_034391.1
Drosophila melanogaster (fruit fly)	CG1418	NP_610539.1
Rattus norvegicus (Norway rat)	Rabac1	NP_113962.1
Xenopus tropicalis (tropical clawed frog)	rabac1	NP_001072225.1
Bos taurus (cattle)	RABAC1	NP_001069043.1
Danio rerio (zebrafish)	rabac1	NP_999945.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003662	XP_003436558.1
Pan troglodytes (chimpanzee)	RABAC1	XP_001152812.1

Gene Ontology
Bibliography

Related articles in PubMed

An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Ta?an M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barab?si AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M
Molecular systems biology12(4)865(2016 Apr)

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

Widespread macromolecular interaction perturbations in human genetic disorders.
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kov?cs IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barab?si AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M
Cell161(3)647-660(2015 Apr)

NDRG2 and PRA1 interact and synergistically inhibit T-cell factor/?-catenin signaling.
Kim JT, Kim JW, Kang YH, Kim KD, Lee SJ, Choi SC, Kim KS, Chae SK, Kim JW, Lim JS, Lee HG
FEBS letters586(22)3962-8(2012 Nov)

A directed protein interaction network for investigating intracellular signal transduction.
Vinayagam A, Stelzl U, Foulle R, Plassmann S, Zenkner M, Timm J, Assmus HE, Andrade-Navarro MA, Wanker EE
Science signaling4(189)rs8(2011 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results suggest that NDRG2 and prenylated Rab acceptor-1 (PRA1) might act synergistically to prevent signaling of T-cell facto/beta-catenin.
Title: NDRG2 and PRA1 interact and synergistically inhibit T-cell factor/?-catenin signaling.

Prenylated Rab acceptor protein 1 (PRA1) was identified as an interacting partner of SNCA.
Title: Human ?-synuclein modulates vesicle trafficking through its interaction with prenylated Rab acceptor protein 1.

These findings delineated novel roles of PRA1 in lipid transport and cell migration.
Title: Proteome-wide dysregulation by PRA1 depletion delineates a role of PRA1 in lipid transport and cell migration.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following RABAC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RABAC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31998	NM_006423.3 Latest version!	Homo sapiens Rab acceptor 1 (RABAC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu31998	NM_006423.2	Homo sapiens Rab acceptor 1 (RABAC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RABAC1 ( NM_006423.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_006414.2 Homo sapiens Rab acceptor 1 (RABAC1), mRNA.

Price & Availability↑

CloneID	OHu31998
Clone ID Related Accession (Same CDS sequence)	NM_006423.2 , NM_006423.3
Accession Version	NM_006423.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-27
Organism	Homo sapiens(human)
Product	prenylated Rab acceptor protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB454056.1, CF242972.1 and AI376198.1. On Jan 30, 2009 this sequence version replaced NM_006423.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ219376.1, ERR279839.134.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGCGC AGAAGGACCA GCAGAAAGAT GCCGAGGCGG AAGGGCTGAG CGGCACGACC 
CTGCTGCCGA AGCTGATTCC CTCCGGTGCA GGCCGGGAGT GGCTGGAGCG GCGCCGCGCG 
ACCATCCGGC CCTGGAGCAC CTTCGTGGAC CAGCAGCGCT TCTCACGGCC CCGCAACCTG 
GGAGAGCTGT GCCAGCGCCT CGTACGCAAC GTGGAGTACT ACCAGAGCAA CTATGTGTTC 
GTGTTCCTGG GCCTCATCCT GTACTGTGTG GTGACGTCCC CTATGTTGCT GGTGGCTCTG 
GCTGTCTTTT TCGGCGCCTG TTACATTCTC TATCTGCGCA CCTTGGAGTC CAAGCTTGTG 
CTCTTTGGCC GAGAGGTGAG CCCAGCGCAT CAGTATGCTC TGGCTGGAGG CATCTCCTTC 
CCCTTCTTCT GGCTGGCTGG TGCGGGCTCG GCCGTCTTCT GGGTGCTGGG AGCCACCCTG 
GTGGTCATCG GCTCCCACGC TGCCTTCCAC CAGATTGAGG CTGTGGACGG GGAGGAGCTG 
CAGATGGAAC CCGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006414.2
CDS	85..642
Translation	MAAQKDQQKDAEAEGLSGTTLLPKLIPSGAGREWLERRRATIRPWSTFVDQQRFSRPRNLGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLESKLVLFGREVSPAHQYALAGGISFPFFWLAGAGSAVFWVLGATLVVIGSHAAFHQIEAVDGEELQMEPV

Target ORF information:

RefSeq Version	NM_006423.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rab acceptor 1 (RABAC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006423.2

ORF Insert Sequence:

ATGGCAGCGC AGAAGGACCA GCAGAAAGAT GCCGAGGCGG AAGGGCTGAG CGGCACGACC 
CTGCTGCCGA AGCTGATTCC CTCCGGTGCA GGCCGGGAGT GGCTGGAGCG GCGCCGCGCG 
ACCATCCGGC CCTGGAGCAC CTTCGTGGAC CAGCAGCGCT TCTCACGGCC CCGCAACCTG 
GGAGAGCTGT GCCAGCGCCT CGTACGCAAC GTGGAGTACT ACCAGAGCAA CTATGTGTTC 
GTGTTCCTGG GCCTCATCCT GTACTGTGTG GTGACGTCCC CTATGTTGCT GGTGGCTCTG 
GCTGTCTTTT TCGGCGCCTG TTACATTCTC TATCTGCGCA CCTTGGAGTC CAAGCTTGTG 
CTCTTTGGCC GAGAGGTGAG CCCAGCGCAT CAGTATGCTC TGGCTGGAGG CATCTCCTTC 
CCCTTCTTCT GGCTGGCTGG TGCGGGCTCG GCCGTCTTCT GGGTGCTGGG AGCCACCCTG 
GTGGTCATCG GCTCCCACGC TGCCTTCCAC CAGATTGAGG CTGTGGACGG GGAGGAGCTG 
CAGATGGAAC CCGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RABAC1 ( NM_006423.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006414.2 Homo sapiens Rab acceptor 1 (RABAC1), mRNA.

Price & Availability↑

CloneID	OHu31998
Clone ID Related Accession (Same CDS sequence)	NM_006423.2 , NM_006423.3
Accession Version	NM_006423.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	prenylated Rab acceptor protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB454056.1, CF242972.1 and AI376198.1. On Nov 23, 2018 this sequence version replaced NM_006423.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.83507.1, SRR5189655.12603.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000222008.11/ ENSP00000222008.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAGCGC AGAAGGACCA GCAGAAAGAT GCCGAGGCGG AAGGGCTGAG CGGCACGACC 
CTGCTGCCGA AGCTGATTCC CTCCGGTGCA GGCCGGGAGT GGCTGGAGCG GCGCCGCGCG 
ACCATCCGGC CCTGGAGCAC CTTCGTGGAC CAGCAGCGCT TCTCACGGCC CCGCAACCTG 
GGAGAGCTGT GCCAGCGCCT CGTACGCAAC GTGGAGTACT ACCAGAGCAA CTATGTGTTC 
GTGTTCCTGG GCCTCATCCT GTACTGTGTG GTGACGTCCC CTATGTTGCT GGTGGCTCTG 
GCTGTCTTTT TCGGCGCCTG TTACATTCTC TATCTGCGCA CCTTGGAGTC CAAGCTTGTG 
CTCTTTGGCC GAGAGGTGAG CCCAGCGCAT CAGTATGCTC TGGCTGGAGG CATCTCCTTC 
CCCTTCTTCT GGCTGGCTGG TGCGGGCTCG GCCGTCTTCT GGGTGCTGGG AGCCACCCTG 
GTGGTCATCG GCTCCCACGC TGCCTTCCAC CAGATTGAGG CTGTGGACGG GGAGGAGCTG 
CAGATGGAAC CCGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006414.2
CDS	30..587
Translation	MAAQKDQQKDAEAEGLSGTTLLPKLIPSGAGREWLERRRATIRPWSTFVDQQRFSRPRNLGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLESKLVLFGREVSPAHQYALAGGISFPFFWLAGAGSAVFWVLGATLVVIGSHAAFHQIEAVDGEELQMEPV

Target ORF information:

RefSeq Version	NM_006423.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rab acceptor 1 (RABAC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006423.3

ORF Insert Sequence:

ATGGCAGCGC AGAAGGACCA GCAGAAAGAT GCCGAGGCGG AAGGGCTGAG CGGCACGACC 
CTGCTGCCGA AGCTGATTCC CTCCGGTGCA GGCCGGGAGT GGCTGGAGCG GCGCCGCGCG 
ACCATCCGGC CCTGGAGCAC CTTCGTGGAC CAGCAGCGCT TCTCACGGCC CCGCAACCTG 
GGAGAGCTGT GCCAGCGCCT CGTACGCAAC GTGGAGTACT ACCAGAGCAA CTATGTGTTC 
GTGTTCCTGG GCCTCATCCT GTACTGTGTG GTGACGTCCC CTATGTTGCT GGTGGCTCTG 
GCTGTCTTTT TCGGCGCCTG TTACATTCTC TATCTGCGCA CCTTGGAGTC CAAGCTTGTG 
CTCTTTGGCC GAGAGGTGAG CCCAGCGCAT CAGTATGCTC TGGCTGGAGG CATCTCCTTC 
CCCTTCTTCT GGCTGGCTGG TGCGGGCTCG GCCGTCTTCT GGGTGCTGGG AGCCACCCTG 
GTGGTCATCG GCTCCCACGC TGCCTTCCAC CAGATTGAGG CTGTGGACGG GGAGGAGCTG 
CAGATGGAAC CCGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An inter-species protein-protein interaction network across vast evolutionary distance.
Molecular systems biology12(4)865(2016 Apr)
Zhong Q,Pevzner SJ,Hao T,Wang Y,Mosca R,Menche J,Taipale M,Ta?an M,Fan C,Yang X,Haley P,Murray RR,Mer F,Gebreab F,Tam S,MacWilliams A,Dricot A,Reichert P,Santhanam B,Ghamsari L,Calderwood MA,Rolland T,Charloteaux B,Lindquist S,Barab?si AL,Hill DE,Aloy P,Cusick ME,Xia Y,Roth FP,Vidal M

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

Widespread macromolecular interaction perturbations in human genetic disorders.
Cell161(3)647-660(2015 Apr)
Sahni N,Yi S,Taipale M,Fuxman Bass JI,Coulombe-Huntington J,Yang F,Peng J,Weile J,Karras GI,Wang Y,Kov?cs IA,Kamburov A,Krykbaeva I,Lam MH,Tucker G,Khurana V,Sharma A,Liu YY,Yachie N,Zhong Q,Shen Y,Palagi A,San-Miguel A,Fan C,Balcha D,Dricot A,Jordan DM,Walsh JM,Shah AA,Yang X,Stoyanova AK,Leighton A,Calderwood MA,Jacob Y,Cusick ME,Salehi-Ashtiani K,Whitesell LJ,Sunyaev S,Berger B,Barab?si AL,Charloteaux B,Hill DE,Hao T,Roth FP,Xia Y,Walhout AJM,Lindquist S,Vidal M

NDRG2 and PRA1 interact and synergistically inhibit T-cell factor/?-catenin signaling.
FEBS letters586(22)3962-8(2012 Nov)
Kim JT,Kim JW,Kang YH,Kim KD,Lee SJ,Choi SC,Kim KS,Chae SK,Kim JW,Lim JS,Lee HG

A directed protein interaction network for investigating intracellular signal transduction.
Science signaling4(189)rs8(2011 Sep)
Vinayagam A,Stelzl U,Foulle R,Plassmann S,Zenkner M,Timm J,Assmus HE,Andrade-Navarro MA,Wanker EE

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RABAC1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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