SELENOP2 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	SELENOP2
Entrez Gene ID	424593
Full Name	selenoprotein P2
Synonyms	SELPB,SEPP1L,SEPP2
General protein information	Preferred Names selenoprotein P2 Names selenoprotein Pb selenoprotein P 2 selenoprotein P, plasma, 1-like
Gene Type	protein-coding
Organism	Gallus gallus(chicken)
Summary	This gene has 5-exon structure similar to chicken selenoprotein P gene (GeneID:431587). These two genes are thought to have arisen by whole genome duplication. This gene encodes a vertebrate-specific selenoprotein that contains a single selenocysteine (Sec) residue compared to 13 Sec residues in chicken selenoprotein P. The exact function of this selenoprotein is not known; however, it is predicted to have a signal peptide, so it is probably secreted like selenoprotein P, and may function as an extracellular antioxidant. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The mRNA for this selenoprotein contains a single SECIS element. [provided by RefSeq, Jul 2017].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001348769.1	NP_001335698.1	selenoprotein Pb precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Selenoprotein Gene Nomenclature.
Gladyshev VN, Arn?r ES, Berry MJ, Brigelius-Floh? R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Floh? L, Green FR, Guig? R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, K?hrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Sandeep Prabhu K, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonovi? M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y
The Journal of biological chemistry291(46)24036-24040(2016 Nov)

Dietary Selenium Status Regulates the Transcriptions of Selenoproteome and Activities of Selenoenzymes in Chicken Kidney at Low or Super-nutritional Levels.
Xu JX, Zhang C, Cao CY, Zhu SY, Li H, Sun YC, Li JL
Biological trace element research170(2)438-48(2016 Apr)

Composition and evolution of the vertebrate and mammalian selenoproteomes.
Mariotti M, Ridge PG, Zhang Y, Lobanov AV, Pringle TH, Guigo R, Hatfield DL, Gladyshev VN
PloS one7(3)e33066(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

At super-nutritional Se, most selenoproteins were upregulated in chicken kidney, but Sepp2 and Sep15 was only upregulated in Se excess (5.0 mg/kg) bird.
Title: Dietary Selenium Status Regulates the Transcriptions of Selenoproteome and Activities of Selenoenzymes in Chicken Kidney at Low or Super-nutritional Levels.

The following SELENOP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SELENOP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa86430	NM_001348769.1 Latest version!	Gallus gallus selenoprotein P2 (SELENOP2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SELENOP2 ( NM_001348769.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001335698.1 Gallus gallus selenoprotein P2 (SELENOP2), mRNA.

Price & Availability↑

CloneID	OGa86430
Clone ID Related Accession (Same CDS sequence)	NM_001348769.1
Accession Version	NM_001348769.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-16
Organism	Gallus gallus(chicken)
Product	selenoprotein Pb precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AADN05000647.1. On Feb 15, 2017 this sequence version replaced XM_003641687.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: ERR2368565.148207.1, ERR2368565.336976.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2201377, SAMEA2201381 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGCCGC TGCTGCTGGC GCTGGCCTCC TGCCTGGGGC TGGCCGTGGC CTCCGAGGGG 
GCCACCAACG GCAGCCGGCT GTGCCACGAG GCCCCGGCGT GGCGGATCAA CGGCTCCAGC 
CCCATGGAGG GCGCGGCAGG GCAGGTGACG GTGGTGGCCC TGCTGAAGGC CAGCTGACAC 
TTCTGCCTGC TGCAGGCCCG CAGCCTCGGG GCCCTGCGGG AGCGGCTGGG ACAGCAGGGG 
GTGAGCGATG TCCGCTATGT GATCGTCAAC GAGCAGGCCC CGCTGTCCCG CGCCATGTTT 
GGGGAGCTGC AGCGCCACGC CCCGCCGGGC GTCCCCGTCC TCCAGCAGCA GCCACACGAG 
CCCGACGTGT GGCAGCTGCT GGGGGGTGAC AAAGACGACT TCCTCGTCTA CGACCGCTGC 
GGCCGCCTGG CCTTCCACAT CCAGCTGCCC TACAGCTTCC TGCACCTGCC CTACGTCGAG 
TCCGCCATCC GCTTCACCCA CCGCAAGGAC TTCTGCGGGA ACTGCTCCCT CTACCCCAAC 
AGCACCCAGG AGGCCAACAG TACCATGGAG GTCCCTGCGA CCCTGACCCC GCTTCCCAAA 
CAGGAGGAGA AGGAATCCGA GACCCCCGCC CACCACCAAC CCAACCATCT CCATCCTCAC 
CACCGCGCAG TTGGCAACGG GACAGCCCCA GAGCCCAGCG GGGACCACAG ACCTGCCCAC 
GCTCACCACC ACCATGGAGC CCATGGCAAA CTCCATCCCA AGGGCCAGAC GCCAGAGGGA 
CGCGATCCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001335698.1
CDS	63..854
Translation	MGPLLLALASCLGLAVASEGATNGSRLCHEAPAWRINGSSPMEGAAGQVTVVALLKAS*HFCLLQARSLGALRERLGQQGVSDVRYVIVNEQAPLSRAMFGELQRHAPPGVPVLQQQPHEPDVWQLLGGDKDDFLVYDRCGRLAFHIQLPYSFLHLPYVESAIRFTHRKDFCGNCSLYPNSTQEANSTMEVPATLTPLPKQEEKESETPAHHQPNHLHPHHRAVGNGTAPEPSGDHRPAHAHHHHGAHGKLHPKGQTPEGRDP

Target ORF information:

RefSeq Version	NM_001348769.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus selenoprotein P2 (SELENOP2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001348769.1

ORF Insert Sequence:

ATGGGGCCGC TGCTGCTGGC GCTGGCCTCC TGCCTGGGGC TGGCCGTGGC CTCCGAGGGG 
GCCACCAACG GCAGCCGGCT GTGCCACGAG GCCCCGGCGT GGCGGATCAA CGGCTCCAGC 
CCCATGGAGG GCGCGGCAGG GCAGGTGACG GTGGTGGCCC TGCTGAAGGC CAGCTGACAC 
TTCTGCCTGC TGCAGGCCCG CAGCCTCGGG GCCCTGCGGG AGCGGCTGGG ACAGCAGGGG 
GTGAGCGATG TCCGCTATGT GATCGTCAAC GAGCAGGCCC CGCTGTCCCG CGCCATGTTT 
GGGGAGCTGC AGCGCCACGC CCCGCCGGGC GTCCCCGTCC TCCAGCAGCA GCCACACGAG 
CCCGACGTGT GGCAGCTGCT GGGGGGTGAC AAAGACGACT TCCTCGTCTA CGACCGCTGC 
GGCCGCCTGG CCTTCCACAT CCAGCTGCCC TACAGCTTCC TGCACCTGCC CTACGTCGAG 
TCCGCCATCC GCTTCACCCA CCGCAAGGAC TTCTGCGGGA ACTGCTCCCT CTACCCCAAC 
AGCACCCAGG AGGCCAACAG TACCATGGAG GTCCCTGCGA CCCTGACCCC GCTTCCCAAA 
CAGGAGGAGA AGGAATCCGA GACCCCCGCC CACCACCAAC CCAACCATCT CCATCCTCAC 
CACCGCGCAG TTGGCAACGG GACAGCCCCA GAGCCCAGCG GGGACCACAG ACCTGCCCAC 
GCTCACCACC ACCATGGAGC CCATGGCAAA CTCCATCCCA AGGGCCAGAC GCCAGAGGGA 
CGCGATCCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Selenoprotein Gene Nomenclature.
The Journal of biological chemistry291(46)24036-24040(2016 Nov)
Gladyshev VN,Arn?r ES,Berry MJ,Brigelius-Floh? R,Bruford EA,Burk RF,Carlson BA,Castellano S,Chavatte L,Conrad M,Copeland PR,Diamond AM,Driscoll DM,Ferreiro A,Floh? L,Green FR,Guig? R,Handy DE,Hatfield DL,Hesketh J,Hoffmann PR,Holmgren A,Hondal RJ,Howard MT,Huang K,Kim HY,Kim IY,K?hrle J,Krol A,Kryukov GV,Lee BJ,Lee BC,Lei XG,Liu Q,Lescure A,Lobanov AV,Loscalzo J,Maiorino M,Mariotti M,Sandeep Prabhu K,Rayman MP,Rozovsky S,Salinas G,Schmidt EE,Schomburg L,Schweizer U,Simonovi? M,Sunde RA,Tsuji PA,Tweedie S,Ursini F,Whanger PD,Zhang Y

Dietary Selenium Status Regulates the Transcriptions of Selenoproteome and Activities of Selenoenzymes in Chicken Kidney at Low or Super-nutritional Levels.
Biological trace element research170(2)438-48(2016 Apr)
Xu JX,Zhang C,Cao CY,Zhu SY,Li H,Sun YC,Li JL

Composition and evolution of the vertebrate and mammalian selenoproteomes.
PloS one7(3)e33066(2012)
Mariotti M,Ridge PG,Zhang Y,Lobanov AV,Pringle TH,Guigo R,Hatfield DL,Gladyshev VN

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SELENOP2 cDNA ORF clone, Gallus gallus(chicken)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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