TLR15 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	TLR15
Entrez Gene ID	421219
Full Name	toll-like receptor 15
General protein information	Preferred Names toll-like receptor 15 Names toll-like receptor 15
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001037835.1	NP_001032924.1	toll-like receptor 15

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Diacylated lipopeptide from Mycoplasma synoviae mediates TLR15 induced innate immune responses.
Oven I, Resman Rus K, Du?ani? D, Ben?ina D, Keeler CL Jr, Narat M
Veterinary research4499(2013 Oct)

Upregulation of chicken TLR4, TLR15 and MyD88 in heterophils and monocyte-derived macrophages stimulated with Eimeria tenella in vitro.
Zhou Z, Wang Z, Cao L, Hu S, Zhang Z, Qin B, Guo Z, Nie K
Experimental parasitology133(4)427-33(2013 Apr)

Polymorphisms of chicken Toll-like receptors 4, 15, and 21 in different breeds.
Ruan WK, Wu YH, An J, Zheng SJ
Poultry science91(10)2512-6(2012 Oct)

[Marek's disease virus can infect chicken brain microglia and promote the transcription of toll-like receptor 15 and 1LB genes].
Yang QL, Chen H, Wei P
Bing du xue bao = Chinese journal of virology27(1)18-25(2011 Jan)

Expression of the avian-specific toll-like receptor 15 in chicken heterophils is mediated by gram-negative and gram-positive bacteria, but not TLR agonists.
Nerren JR, He H, Genovese K, Kogut MH
Veterinary immunology and immunopathology136(1-2)151-6(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The N-terminal diacylated lipopeptide representing the amino-terminal portion of its mature haemagglutinin protein of Mycoplasma synoviae, significantly induces the expression of TLR15, but not TLR1 and TLR2 in chicken macrophages and chondrocytes.
Title: Diacylated lipopeptide from Mycoplasma synoviae mediates TLR15 induced innate immune responses.

The results suggest that ChTLR4 and ChTLR15 are involved in response to E. tenella infection, and may operate in a MyD88-dependent manner for host defense.
Title: Upregulation of chicken TLR4, TLR15 and MyD88 in heterophils and monocyte-derived macrophages stimulated with Eimeria tenella in vitro.

Marek's disease virus infection promotes the transcription of TLR15 and TLR1Lb in brain.
Title: [Marek's disease virus can infect chicken brain microglia and promote the transcription of toll-like receptor 15 and 1LB genes].

TLR15 recognizes a unique, non-secreted, heat-stabile component of both Gram-negative and Gram-positive bacteria commonly found in and/or capable of causing disease
Title: Expression of the avian-specific toll-like receptor 15 in chicken heterophils is mediated by gram-negative and gram-positive bacteria, but not TLR agonists.

Heterophils from chickens resistant to infection with Salmonella enterica serovar enteritidis had significantly greater levels of TLR 15 mRNA expression prior to & following stimulation with SE than heterophils from susceptible chickens.
Title: Differential mRNA expression of the avian-specific toll-like receptor 15 between heterophils from Salmonella-susceptible and -resistant chickens.

The following TLR15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TLR15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa01161	NM_001037835.1 Latest version!	Gallus gallus toll-like receptor 15 (TLR15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TLR15 ( NM_001037835.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001032924.1 Gallus gallus toll-like receptor 15 (TLR15), mRNA.

Price & Availability↑

CloneID	OGa01161
Clone ID Related Accession (Same CDS sequence)	NM_001037835.1
Accession Version	NM_001037835.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2607bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-23
Organism	Gallus gallus(chicken)
Product	toll-like receptor 15
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ267901.1. On Dec 19, 2005 this sequence version replaced XM_419294.1. ##Evidence-Data-START## Transcript exon combination :: DQ267901.1 [ECO:0000332] ##Evidence-Data-END##

ATGAGGATCC TTATTGGGAG TCTTTATTTC TACTTCATTT CTTTCTTATT CAGTAAAGTA 
AATGGATTCC TAACTCAGAG AACATCTCCA GTGTCTTCCT TCCCATTTTA TAACTACTCT 
TACTTAAACC TCTCTTCTGT ATCACAAGCA CAAGCTCCCA AAACAGCGAG AGCTCTCAAC 
TTCTCATATA ATGCAATTGA AAAAATAACC AAAAGAGACT TTGAAGGTTT TCATGTACTG 
GAAGTTTTGG ACCTTTCTCA CAATCACATT AAGGACATTG AACCTGGTGC ATTTGAGAAC 
CTGCTCAGCC TTGTTTCTGT GGATTTATCA TTTAATGATA AGAATCTTCT GGTATCTGGT 
CTTGCACCTC ACCTGAAACT CATACCGACC AGCGGAGCCT CGGGGCCTTC ACAGATTTAT 
ATGTATTTTC AAAAATCAGC AGAGGCTGCT CTGGAGCCTT CTGCACCAGC TGAACTGCTG 
CCACATTTGG AAGATCCACC CAATCCAGGA AATGTTAACC CAAGATTCAG ACAAAGAAGA 
ACAGAGGAAA ATAAAACTTC CCCTCCAGCA GCCACGCTGA GGCCTGACTT GTGTGGAGCA 
CCGATCAATG GGTTGCTTGA CCTATCAAGG ACCAAACTGT CTAATGAAGA GCTGACAGCA 
AAATTGGATG CAGACCTCTG CCAAGCTCAG CTGGGCACTG TTTTGGAGTT TAACATTAGT 
CACAGCGACC TGGAGATGGA TCTTCTATCT CTGTTCATCC TGTTTTTGCC GATGAAAGAT 
ATACAGTCCG TTGATGCCAG CTACAACAGA ATAACAATTA ACAACATAGA CGTTGAAGCA 
ATCTGTCACT TCCCATTCAG CAACTTTTCA TTTTTAAATA TCAGCAACAA TCCCATCAAC 
AGCCTGGAAA CTGTGTGTCT CCCAGCAAGC ATCACAGTCA TTGATCTGTC CTTCACAAAC 
ATTAGTACAA TACCTGCAAA TTTTGCTAAG AAGTTATCTA AATTAGAACG TATGTACGTT 
CAAGGAAATC AGCTCATATA TACCGTACGT CCAGAAAACC CCAGTGCAAC CCCAAGGCCT 
CCCCCTGGAA CTGTACAAAT CAGCGCTATT TCCTTGGTCA GAAACCAGGC TGGTACACCC 
ATCGAAAGCC TTCCAGAGAG CGTAAAACAC CTGAAAGTGT CCAACTGCTC CATCGTAGAA 
CTTCCAGAAT GGTTTGCCAA CAGAATGCAA GAACTACTAT TTCTGGATCT CAGCAGCAAT 
CGGATTTCCA TGCTTCCTGA CCTACCTATC TCTCTGCAGC AACTTGACAT AAGTAACAGC 
GATATTAAAA TAATACCCCC TAGGTTTAAA TCTCTCTCCA ACGTAACTGT ATTTAATATT 
CAAAATAATA AACTTACAGA GATGCATCCC GAATACTTCC CATCCACTTT AACGACATGC 
GATATTAGTA AAAATAAGTT GAAGGTGCTA TCATTAACCA AAGCCCTAGA GAACCTCGAA 
TCACTTAATG TCTCTGGAAA CCTAATAACC AGACTAGAAC CTGCCTGCCA ACTTCCTTCA 
CTCACTAACC TGGACAGTAG TCACAACCTG ATTTCAGAAC TCCCTGACCA TTTGGGGCAA 
TCTCTCCTGA TGCTGAAGCA TTTTAATTTA TCAGGGAATA AGATCTCCTT CCTGCAGCGC 
GGCTCCCTCC CAGCTTCCCT GGAGGAGCTG GACATTAGCG ACAACGCCAT CACTACCATA 
GTGCAGGATA CTTTTGGACA GTTAACAAGT TTGAGCGTTC TGACTGTTCA AGGTAAACAT 
TTCTTTTGTA ACTGCGACTT GTACTGGTTT GTGAACATCT ACATCCGTAA CCCGCATTTG 
CAGATAAATG GCAAAGATGA TCTCAGGTGC AGCTTTCCAC CAGACAGACG GGGCTCGCTG 
GTGAAGAGCA GTAATCTCAC ACTTCTGCAC TGCTCCCTGG GCATTCAGAT GGCCATTACA 
GCTTGTATGG CCATCCTTGT CGTTCTGGTG CTAACGGGCT TATGCTGGCG CTTTGATGGG 
CTGTGGTATG TGAGAATGGG CTGGTACTGG TGTATGGCAA AGAGGAGGCA GTACAAGAAG 
AGGCCAGAAA ATAAGCCCTT CGATGCCTTC ATTTCATACA GCGAGCACGA TGCAGACTGG 
ACGAAGGAGC ATCTACTGAA AAAACTGGAA ACTGATGGAT TCAAGATATG TTATCATGAG 
AGAGATTTCA AACCAGGGCA TCCTGTACTT GGCAACATTT TTTACTGCAT AGAGAACAGC 
CACAAAGTCC TTTTTGTTCT CTCTCCCAGT TTTGTAAATA GCTGCTGGTG TCAGTATGAA 
CTGTATTTTG CTGAACACCG GGTCCTGGAT GAAAATCAGG ATTCCCTCAT TATGGTAGTG 
CTGGAAGACC TCCCGCCCGA CAGCGTGCCT CAGAAGTTCA GCAAACTCAG GAAGCTGCTG 
AAAAGAAAAA CCTACTTAAA GTGGAGCCCC GAAGAACACA AACAGAAGAT TTTCTGGCAT 
CAGCTGGCAG CTGTCCTAAA AACAACCAAT GAACCACTGG TGAGAGCAGA AAATGGACCC 
AATGAGGATG TAATTGAGAT GGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032924.1
CDS	1..2607
Translation	MRILIGSLYFYFISFLFSKVNGFLTQRTSPVSSFPFYNYSYLNLSSVSQAQAPKTARALNFSYNAIEKITKRDFEGFHVLEVLDLSHNHIKDIEPGAFENLLSLVSVDLSFNDKNLLVSGLAPHLKLIPTSGASGPSQIYMYFQKSAEAALEPSAPAELLPHLEDPPNPGNVNPRFRQRRTEENKTSPPAATLRPDLCGAPINGLLDLSRTKLSNEELTAKLDADLCQAQLGTVLEFNISHSDLEMDLLSLFILFLPMKDIQSVDASYNRITINNIDVEAICHFPFSNFSFLNISNNPINSLETVCLPASITVIDLSFTNISTIPANFAKKLSKLERMYVQGNQLIYTVRPENPSATPRPPPGTVQISAISLVRNQAGTPIESLPESVKHLKVSNCSIVELPEWFANRMQELLFLDLSSNRISMLPDLPISLQQLDISNSDIKIIPPRFKSLSNVTVFNIQNNKLTEMHPEYFPSTLTTCDISKNKLKVLSLTKALENLESLNVSGNLITRLEPACQLPSLTNLDSSHNLISELPDHLGQSLLMLKHFNLSGNKISFLQRGSLPASLEELDISDNAITTIVQDTFGQLTSLSVLTVQGKHFFCNCDLYWFVNIYIRNPHLQINGKDDLRCSFPPDRRGSLVKSSNLTLLHCSLGIQMAITACMAILVVLVLTGLCWRFDGLWYVRMGWYWCMAKRRQYKKRPENKPFDAFISYSEHDADWTKEHLLKKLETDGFKICYHERDFKPGHPVLGNIFYCIENSHKVLFVLSPSFVNSCWCQYELYFAEHRVLDENQDSLIMVVLEDLPPDSVPQKFSKLRKLLKRKTYLKWSPEEHKQKIFWHQLAAVLKTTNEPLVRAENGPNEDVIEME

Target ORF information:

RefSeq Version	NM_001037835.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus toll-like receptor 15 (TLR15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037835.1

ORF Insert Sequence:

ATGAGGATCC TTATTGGGAG TCTTTATTTC TACTTCATTT CTTTCTTATT CAGTAAAGTA 
AATGGATTCC TAACTCAGAG AACATCTCCA GTGTCTTCCT TCCCATTTTA TAACTACTCT 
TACTTAAACC TCTCTTCTGT ATCACAAGCA CAAGCTCCCA AAACAGCGAG AGCTCTCAAC 
TTCTCATATA ATGCAATTGA AAAAATAACC AAAAGAGACT TTGAAGGTTT TCATGTACTG 
GAAGTTTTGG ACCTTTCTCA CAATCACATT AAGGACATTG AACCTGGTGC ATTTGAGAAC 
CTGCTCAGCC TTGTTTCTGT GGATTTATCA TTTAATGATA AGAATCTTCT GGTATCTGGT 
CTTGCACCTC ACCTGAAACT CATACCGACC AGCGGAGCCT CGGGGCCTTC ACAGATTTAT 
ATGTATTTTC AAAAATCAGC AGAGGCTGCT CTGGAGCCTT CTGCACCAGC TGAACTGCTG 
CCACATTTGG AAGATCCACC CAATCCAGGA AATGTTAACC CAAGATTCAG ACAAAGAAGA 
ACAGAGGAAA ATAAAACTTC CCCTCCAGCA GCCACGCTGA GGCCTGACTT GTGTGGAGCA 
CCGATCAATG GGTTGCTTGA CCTATCAAGG ACCAAACTGT CTAATGAAGA GCTGACAGCA 
AAATTGGATG CAGACCTCTG CCAAGCTCAG CTGGGCACTG TTTTGGAGTT TAACATTAGT 
CACAGCGACC TGGAGATGGA TCTTCTATCT CTGTTCATCC TGTTTTTGCC GATGAAAGAT 
ATACAGTCCG TTGATGCCAG CTACAACAGA ATAACAATTA ACAACATAGA CGTTGAAGCA 
ATCTGTCACT TCCCATTCAG CAACTTTTCA TTTTTAAATA TCAGCAACAA TCCCATCAAC 
AGCCTGGAAA CTGTGTGTCT CCCAGCAAGC ATCACAGTCA TTGATCTGTC CTTCACAAAC 
ATTAGTACAA TACCTGCAAA TTTTGCTAAG AAGTTATCTA AATTAGAACG TATGTACGTT 
CAAGGAAATC AGCTCATATA TACCGTACGT CCAGAAAACC CCAGTGCAAC CCCAAGGCCT 
CCCCCTGGAA CTGTACAAAT CAGCGCTATT TCCTTGGTCA GAAACCAGGC TGGTACACCC 
ATCGAAAGCC TTCCAGAGAG CGTAAAACAC CTGAAAGTGT CCAACTGCTC CATCGTAGAA 
CTTCCAGAAT GGTTTGCCAA CAGAATGCAA GAACTACTAT TTCTGGATCT CAGCAGCAAT 
CGGATTTCCA TGCTTCCTGA CCTACCTATC TCTCTGCAGC AACTTGACAT AAGTAACAGC 
GATATTAAAA TAATACCCCC TAGGTTTAAA TCTCTCTCCA ACGTAACTGT ATTTAATATT 
CAAAATAATA AACTTACAGA GATGCATCCC GAATACTTCC CATCCACTTT AACGACATGC 
GATATTAGTA AAAATAAGTT GAAGGTGCTA TCATTAACCA AAGCCCTAGA GAACCTCGAA 
TCACTTAATG TCTCTGGAAA CCTAATAACC AGACTAGAAC CTGCCTGCCA ACTTCCTTCA 
CTCACTAACC TGGACAGTAG TCACAACCTG ATTTCAGAAC TCCCTGACCA TTTGGGGCAA 
TCTCTCCTGA TGCTGAAGCA TTTTAATTTA TCAGGGAATA AGATCTCCTT CCTGCAGCGC 
GGCTCCCTCC CAGCTTCCCT GGAGGAGCTG GACATTAGCG ACAACGCCAT CACTACCATA 
GTGCAGGATA CTTTTGGACA GTTAACAAGT TTGAGCGTTC TGACTGTTCA AGGTAAACAT 
TTCTTTTGTA ACTGCGACTT GTACTGGTTT GTGAACATCT ACATCCGTAA CCCGCATTTG 
CAGATAAATG GCAAAGATGA TCTCAGGTGC AGCTTTCCAC CAGACAGACG GGGCTCGCTG 
GTGAAGAGCA GTAATCTCAC ACTTCTGCAC TGCTCCCTGG GCATTCAGAT GGCCATTACA 
GCTTGTATGG CCATCCTTGT CGTTCTGGTG CTAACGGGCT TATGCTGGCG CTTTGATGGG 
CTGTGGTATG TGAGAATGGG CTGGTACTGG TGTATGGCAA AGAGGAGGCA GTACAAGAAG 
AGGCCAGAAA ATAAGCCCTT CGATGCCTTC ATTTCATACA GCGAGCACGA TGCAGACTGG 
ACGAAGGAGC ATCTACTGAA AAAACTGGAA ACTGATGGAT TCAAGATATG TTATCATGAG 
AGAGATTTCA AACCAGGGCA TCCTGTACTT GGCAACATTT TTTACTGCAT AGAGAACAGC 
CACAAAGTCC TTTTTGTTCT CTCTCCCAGT TTTGTAAATA GCTGCTGGTG TCAGTATGAA 
CTGTATTTTG CTGAACACCG GGTCCTGGAT GAAAATCAGG ATTCCCTCAT TATGGTAGTG 
CTGGAAGACC TCCCGCCCGA CAGCGTGCCT CAGAAGTTCA GCAAACTCAG GAAGCTGCTG 
AAAAGAAAAA CCTACTTAAA GTGGAGCCCC GAAGAACACA AACAGAAGAT TTTCTGGCAT 
CAGCTGGCAG CTGTCCTAAA AACAACCAAT GAACCACTGG TGAGAGCAGA AAATGGACCC 
AATGAGGATG TAATTGAGAT GGAATGA