Su(var)3-9 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Su(var)3-9
Entrez Gene ID	41483
Full Name	Suppressor of variegation 3-9
Synonyms	CG43664,CG6476,Dmel\CG43664,Dmel_CG6476,E(var)3-2,SU(VAR)3-9,SUV39,SUV39H1,Su(VAR)3-9,Su(Var)3-9,Su(var),Su(var) 3-9,Su(var)3-902,Su(var)306,Su(var)310,Su(var)328,Su-var(3)9,Su-var(3)902,SuVar3-9,Suv 3-9,Suvar(3)9,Suvar3-9,Suvar39,caa56376 Suvar39 Dm,dSU(VAR)3-9,dSu(var)3-9,ptn,su(var)3-9
General protein information	Preferred Names Suppressor of variegation 3-9 Names CG43664 gene product from transcript CG43664-RA CG43664-PA Su(var)3-9-PA enhancer of variegation 3-2 histone methyltransferase pitkin suppressor of variegation 3-9 suppressor of variegation 306 suppressor of variegation 310 suppressor of variegation 328
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 88E6-88E8\|3-56.4 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_079633.3	NP_524357.2	suppressor of variegation 3-9

Pathways from BioSystems

Homologies

Schizosaccharomyces pombe (fission yeast)	clr4	NP_595186.1
Danio rerio (zebrafish)	suv39h1a	NP_001003592.1
Magnaporthe oryzae (rice blast fungus)	MGG_06852	XP_003709573.1
Neurospora crassa	NCU04402	XP_957479.2
Drosophila melanogaster (fruit fly)	Su(var)3-9	NP_524357.2

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results suggest that SU(VAR)3-9 targets RRP6 to a subset of heterochromatic loci where RRP6 degrades chromatin-associated non-coding RNAs in a process that is necessary to maintain the packaging of the heterochromatin
Title: An Interaction between RRP6 and SU(VAR)3-9 Targets RRP6 to Heterochromatin and Contributes to Heterochromatin Maintenance in Drosophila melanogaster.

H1 plays a key role in silencing by tethering Su(var)3-9 to heterochromatin.
Title: Drosophila H1 regulates the genetic activity of heterochromatin by recruitment of Su(var)3-9.

The results showed that on chromosome 4, Su(var)3-9, SETDB1 and HP1a target the same genes.
Title: HP1a, Su(var)3-9, SETDB1 and POF stimulate or repress gene expression depending on genomic position, gene length and expression pattern in Drosophila melanogaster.

The following Su(var)3-9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Su(var)3-9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa04651	NM_079633.3 Latest version!	Drosophila melanogaster suppressor of variegation 3-9 (Su(var)3-9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Su(var)3-9 ( NM_079633.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524357.2 Drosophila melanogaster suppressor of variegation 3-9 (Su(var)3-9), mRNA.

Price & Availability↑

CloneID	OFa04651
Clone ID Related Accession (Same CDS sequence)	NM_079633.3
Accession Version	NM_079633.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1908bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	suppressor of variegation 3-9
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jan 16, 2013 this sequence version replaced NM_079633.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCCACGG CTGAAGCCCA GATCGGTGTG AACAGGAACT TGCAGAAGCA GGACCTCAGC 
AACTTGGACG TCTCTAAACT AACGCCTCTA TCACCGGAGG TCATCTCCCG ACAGGCGACC 
ATCAACATCG GCACCATCGG TCATGTGGCT CACGGCAAAT CCACGGTGGT CAAAGCCATA 
TCCGGCGTGC AGACTGTGCG CTTCAAGAAC GAACTGGAGC GCAACATCAC AATCAAGCTG 
GAACGCTTGA GCGAAAAAAA AATCAAAAAT CTTTTGACCT CCAAGCAGCA GCGACAGCAG 
TATGAAATCA AACAGCGTTC AATGCTGCGC CACCTGGCCG AATTGCGGCG ACATAGCCGA 
TTCCGCCGCC TCTGCACCAA GCCAGCTTCG TCTTCCATGC CAGCATCCAC CTCCAGTGTA 
GATAGACGCA CCACCCGGCG AAGCACCAGT CAGACCTCAC TGAGTCCAAG CAATAGTAGC 
GGCTATGGCA GCGTTTTTGG CTGCGAGGAA CATGATGTGG ACAAAATACC CAGTCTCAAC 
GGATTCGCCA AACTGAAGCG TCGACGCAGC AGTTGTGTGG GCGCCCCAAC TCCCAACTCC 
AAGCGGTCGA AAAATAACAT GGGAGTAATT GCCAAAAGGC CGCCCAAAGG AGAGTACGTT 
GTGGAGCGTA TTGAATGCGT CGAGATGGAT CAATATCAGC CAGTCTTCTT CGTCAAATGG 
CTGGGATACC ATGATAGCGA GAACACCTGG GAAAGTCTTG CCAACGTGGC CGACTGCGCC 
GAAATGGAGA AGTTTGTGGA GCGGCATCAG CAGCTCTACG AGATATACAT AGCCAAGATA 
ACCACTGAGC TTGAGAAGCA GCTGGAGGCA TTGCCACTAA TGGAGAACAT TACGGTGGCC 
GAAGTAGACG CCTATGAGCC ACTCAATCTG CAGATCGATC TTATACTGCT CGCCCAATAT 
CGCGCTGCTG GCAGTCGAAG CCAAAGGGAA CCGCAGAAAA TTGGAGAACG AGCCCTGAAA 
AGCATGCAAA TCAAGCGGGC CCAATTTGTA CGACGCAAGC AGTTGGCTGA TCTAGCATTG 
TTCGAGAAGC GCATGAATCA TGTGGAGAAA CCGTCACCGC CAATACGTGT TGAGAACAAC 
ATTGATCTGG ACACCATAGA CAGCAATTTC ATGTACATAC ATGATAACAT AATCGGCAAG 
GATGTGCCCA AGCCGGAAGC GGGGATTGTG GGCTGTAAGT GCACTGAAGA CACAGAGGAG 
TGTACTGCCT CTACGAAGTG TTGTGCCCGC TTCGCCGGCG AGCTGTTCGC CTACGAGCGA 
AGCACACGGC GCTTGCGCCT TCGTCCCGGA AGTGCCATCT ATGAGTGCAA TAGCCGCTGC 
TCGTGCGATT CAAGCTGCTC CAACCGTCTG GTGCAGCACG GACGCCAGGT ACCGTTGGTG 
CTGTTTAAGA CCGCCAACGG CAGCGGATGG GGGGTGCGAG CCGCAACTGC CTTGCGTAAG 
GGTGAATTTG TGTGCGAGTA CATTGGAGAG ATCATCACCA GCGATGAGGC AAATGAGCGC 
GGCAAGGCGT ATGACGACAA TGGGAGGACA TATCTGTTCG ACTTGGATTA CAACACAGCT 
CAGGATAGCG AGTACACTAT CGATGCAGCT AACTATGGCA ACATCTCGCA CTTTATCAAT 
CACTCTTGCG ATCCTAATCT CGCCGTGTTC CCCTGTTGGA TCGAGCACCT GAATGTCGCG 
CTGCCGCACC TCGTGTTCTT CACACTGCGT CCAATCAAGG CGGGCGAGGA GTTGAGCTTC 
GACTACATTC GCGCGGACAA CGAAGATGTG CCCTACGAGA ACCTCTCGAC AGCTGTGCGT 
GTCGAGTGCC GCTGCGGAGC TGATAATTGC AGAAAGGTCC TCTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524357.2
CDS	112..2019
Translation	MATAEAQIGVNRNLQKQDLSNLDVSKLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNITIKLERLSEKKIKNLLTSKQQRQQYEIKQRSMLRHLAELRRHSRFRRLCTKPASSSMPASTSSVDRRTTRRSTSQTSLSPSNSSGYGSVFGCEEHDVDKIPSLNGFAKLKRRRSSCVGAPTPNSKRSKNNMGVIAKRPPKGEYVVERIECVEMDQYQPVFFVKWLGYHDSENTWESLANVADCAEMEKFVERHQQLYEIYIAKITTELEKQLEALPLMENITVAEVDAYEPLNLQIDLILLAQYRAAGSRSQREPQKIGERALKSMQIKRAQFVRRKQLADLALFEKRMNHVEKPSPPIRVENNIDLDTIDSNFMYIHDNIIGKDVPKPEAGIVGCKCTEDTEECTASTKCCARFAGELFAYERSTRRLRLRPGSAIYECNSRCSCDSSCSNRLVQHGRQVPLVLFKTANGSGWGVRAATALRKGEFVCEYIGEIITSDEANERGKAYDDNGRTYLFDLDYNTAQDSEYTIDAANYGNISHFINHSCDPNLAVFPCWIEHLNVALPHLVFFTLRPIKAGEELSFDYIRADNEDVPYENLSTAVRVECRCGADNCRKVLF

Target ORF information:

RefSeq Version	NM_079633.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster suppressor of variegation 3-9 (Su(var)3-9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079633.3

ORF Insert Sequence:

ATGGCCACGG CTGAAGCCCA GATCGGTGTG AACAGGAACT TGCAGAAGCA GGACCTCAGC 
AACTTGGACG TCTCTAAACT AACGCCTCTA TCACCGGAGG TCATCTCCCG ACAGGCGACC 
ATCAACATCG GCACCATCGG TCATGTGGCT CACGGCAAAT CCACGGTGGT CAAAGCCATA 
TCCGGCGTGC AGACTGTGCG CTTCAAGAAC GAACTGGAGC GCAACATCAC AATCAAGCTG 
GAACGCTTGA GCGAAAAAAA AATCAAAAAT CTTTTGACCT CCAAGCAGCA GCGACAGCAG 
TATGAAATCA AACAGCGTTC AATGCTGCGC CACCTGGCCG AATTGCGGCG ACATAGCCGA 
TTCCGCCGCC TCTGCACCAA GCCAGCTTCG TCTTCCATGC CAGCATCCAC CTCCAGTGTA 
GATAGACGCA CCACCCGGCG AAGCACCAGT CAGACCTCAC TGAGTCCAAG CAATAGTAGC 
GGCTATGGCA GCGTTTTTGG CTGCGAGGAA CATGATGTGG ACAAAATACC CAGTCTCAAC 
GGATTCGCCA AACTGAAGCG TCGACGCAGC AGTTGTGTGG GCGCCCCAAC TCCCAACTCC 
AAGCGGTCGA AAAATAACAT GGGAGTAATT GCCAAAAGGC CGCCCAAAGG AGAGTACGTT 
GTGGAGCGTA TTGAATGCGT CGAGATGGAT CAATATCAGC CAGTCTTCTT CGTCAAATGG 
CTGGGATACC ATGATAGCGA GAACACCTGG GAAAGTCTTG CCAACGTGGC CGACTGCGCC 
GAAATGGAGA AGTTTGTGGA GCGGCATCAG CAGCTCTACG AGATATACAT AGCCAAGATA 
ACCACTGAGC TTGAGAAGCA GCTGGAGGCA TTGCCACTAA TGGAGAACAT TACGGTGGCC 
GAAGTAGACG CCTATGAGCC ACTCAATCTG CAGATCGATC TTATACTGCT CGCCCAATAT 
CGCGCTGCTG GCAGTCGAAG CCAAAGGGAA CCGCAGAAAA TTGGAGAACG AGCCCTGAAA 
AGCATGCAAA TCAAGCGGGC CCAATTTGTA CGACGCAAGC AGTTGGCTGA TCTAGCATTG 
TTCGAGAAGC GCATGAATCA TGTGGAGAAA CCGTCACCGC CAATACGTGT TGAGAACAAC 
ATTGATCTGG ACACCATAGA CAGCAATTTC ATGTACATAC ATGATAACAT AATCGGCAAG 
GATGTGCCCA AGCCGGAAGC GGGGATTGTG GGCTGTAAGT GCACTGAAGA CACAGAGGAG 
TGTACTGCCT CTACGAAGTG TTGTGCCCGC TTCGCCGGCG AGCTGTTCGC CTACGAGCGA 
AGCACACGGC GCTTGCGCCT TCGTCCCGGA AGTGCCATCT ATGAGTGCAA TAGCCGCTGC 
TCGTGCGATT CAAGCTGCTC CAACCGTCTG GTGCAGCACG GACGCCAGGT ACCGTTGGTG 
CTGTTTAAGA CCGCCAACGG CAGCGGATGG GGGGTGCGAG CCGCAACTGC CTTGCGTAAG 
GGTGAATTTG TGTGCGAGTA CATTGGAGAG ATCATCACCA GCGATGAGGC AAATGAGCGC 
GGCAAGGCGT ATGACGACAA TGGGAGGACA TATCTGTTCG ACTTGGATTA CAACACAGCT 
CAGGATAGCG AGTACACTAT CGATGCAGCT AACTATGGCA ACATCTCGCA CTTTATCAAT 
CACTCTTGCG ATCCTAATCT CGCCGTGTTC CCCTGTTGGA TCGAGCACCT GAATGTCGCG 
CTGCCGCACC TCGTGTTCTT CACACTGCGT CCAATCAAGG CGGGCGAGGA GTTGAGCTTC 
GACTACATTC GCGCGGACAA CGAAGATGTG CCCTACGAGA ACCTCTCGAC AGCTGTGCGT 
GTCGAGTGCC GCTGCGGAGC TGATAATTGC AGAAAGGTCC TCTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Su(var)3-9 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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