h cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	h
Entrez Gene ID	38995
Full Name	hairy
Synonyms	8247,CG6494,Dmel\CG6494,H,HRY,Hairy,bHLHb39,bHLHc14,brr,dDr1,hry,l(3)08247,l(3)rM384
General protein information	Preferred Names hairy Names CG6494 gene product from transcript CG6494-RB CG6494-PA CG6494-PB barrel h-PA h-PB
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3L Map Location: 66D10-66D10\|3-26.5 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001014577.2	NP_001014577.1	hairy, isoform B
NM_079253.4	NP_523977.2	hairy, isoform A

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	HES1	NP_989803.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006699	XP_316733.3
Danio rerio (zebrafish)	her9	NP_571948.1
Drosophila melanogaster (fruit fly)	h	NP_523977.2
Xenopus tropicalis (tropical clawed frog)	hes4	NP_988870.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

argue that the role emc, h and sr in development of the flight apparatus preceded their activities for macrochaete patterning
Title: The bristle patterning genes hairy and extramacrochaetae regulate the development of structures required for flight in Diptera.

These findings question whether hairy is an important regulator of the progression of retinal differentiation in Drosophila, alone or redundantly with extramacrochaete.
Title: The role of the bHLH protein hairy in morphogenetic furrow progression in the developing Drosophila eye.

In this study, the authors show that Dgrn is a negative regulator of the repressor Hairy and its corepressor Groucho (Gro/transducin-like enhancer (TLE)) during embryonic segmentation and neurogenesis.
Title: Degringolade, a SUMO-targeted ubiquitin ligase, inhibits Hairy/Groucho-mediated repression.

Hairy induces widespread histone deacetylation and inhibits the recruitment of basal machinery without inducing chromatin compaction.
Title: Long- and short-range transcriptional repressors induce distinct chromatin states on repressed genes.

Studies demonstrate a novel role for Hairy in restriction of the terminal cell fate by limiting the domain of bnl expression in surrounding muscle cells such that only a single dorsal branch cell becomes specified as a terminal cell.
Title: The bHLH transcription factor, hairy, refines the terminal cell fate in the Drosophila embryonic trachea.

The following h gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the h cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa17929	NM_079253.4 Latest version!	Drosophila melanogaster hairy (h), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$258.30 $369.00
OFa17929	NM_001014577.2 Latest version!	Drosophila melanogaster hairy (h), transcript variant B, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$258.30 $369.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

h ( NM_001014577.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001014577.1 Drosophila melanogaster hairy (h), transcript variant B, mRNA.

Price & Availability↑

CloneID	OFa17929
Clone ID Related Accession (Same CDS sequence)	NM_001014577.2 , NM_079253.4
Accession Version	NM_001014577.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	hairy, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_001014577.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGTTACCG GCGTAACAGC AGCCAACATG ACCAACGTTC TGGGCACCGC CGTTGTGCCG 
GCCCAGCTCA AGGAGACGCC GCTCAAAAGT GACCGTCGGT CGAACAAGCC CATCATGGAG 
AAACGCCGAC GTGCCCGTAT TAACAACTGT CTCAATGAAC TCAAGACTCT GATTCTGGAT 
GCCACCAAAA AAGACCCGGC TCGCCACTCC AAATTGGAAA AGGCCGACAT TCTGGAGAAG 
ACAGTAAAGC ATCTGCAGGA GCTGCAGCGC CAGCAGGCAG CCATGCAGCA GGCCGCCGAT 
CCCAAGATTG TGAACAAATT CAAGGCCGGA TTCGCCGACT GTGTGAACGA GGTTAGCCGC 
TTTCCCGGCA TCGAGCCCGC CCAGCGTCGT CGCCTGCTAC AGCACCTGAG CAACTGCATC 
AATGGCGTTA AGACAGAGCT GCACCAGCAG CAGCGCCAGC AGCAACAGCA GTCCATCCAC 
GCCCAGATGC TGCCCTCGCC GCCCAGCTCG CCGGAGCAGG ATAGCCAGCA GGGAGCAGCG 
GCACCCTACC TCTTTGGTAT CCAGCAGACG GCCAGCGGTT ACTTTCTGCC CAATGGCATG 
CAGGTGATCC CCACCAAGCT GCCCAACGGT AGCATTGCCC TCGTGTTGCC CCAGAGCCTG 
CCCCAGCAGC AGCAGCAACA GTTGCTGCAG CACCAACAGC AGCAGCAGCA ACTCGCCGTC 
GCAGCAGCAG CAGCGGCCGC AGCAGCAGCA CAACAGCAAC CCATGTTGGT CAGCATGCCC 
CAGCGTACAG CCAGCACCGG ATCCGCCAGC TCGCACTCCT CCGCCGGATA CGAGTCGGCG 
CCCGGAAGCA GCAGCAGCTG TAGCTACGCC CCGCCCAGTC CGGCCAACTC TAGCTACGAG 
CCCATGGACA TCAAGCCATC GGTCATCCAG CGCGTGCCAA TGGAGCAGCA GCCCCTGTCG 
CTGGTGATCA AGAAGCAGAT CAAGGAGGAG GAGCAGCCCT GGCGGCCCTG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001014577.1
CDS	492..1505
Translation	MVTGVTAANMTNVLGTAVVPAQLKETPLKSDRRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQQAAMQQAADPKIVNKFKAGFADCVNEVSRFPGIEPAQRRRLLQHLSNCINGVKTELHQQQRQQQQQSIHAQMLPSPPSSPEQDSQQGAAAPYLFGIQQTASGYFLPNGMQVIPTKLPNGSIALVLPQSLPQQQQQQLLQHQQQQQQLAVAAAAAAAAAAQQQPMLVSMPQRTASTGSASSHSSAGYESAPGSSSSCSYAPPSPANSSYEPMDIKPSVIQRVPMEQQPLSLVIKKQIKEEEQPWRPW

Target ORF information:

RefSeq Version	NM_001014577.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster hairy (h), transcript variant B, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001014577.2

ORF Insert Sequence:

ATGGTTACCG GCGTAACAGC AGCCAACATG ACCAACGTTC TGGGCACCGC CGTTGTGCCG 
GCCCAGCTCA AGGAGACGCC GCTCAAAAGT GACCGTCGGT CGAACAAGCC CATCATGGAG 
AAACGCCGAC GTGCCCGTAT TAACAACTGT CTCAATGAAC TCAAGACTCT GATTCTGGAT 
GCCACCAAAA AAGACCCGGC TCGCCACTCC AAATTGGAAA AGGCCGACAT TCTGGAGAAG 
ACAGTAAAGC ATCTGCAGGA GCTGCAGCGC CAGCAGGCAG CCATGCAGCA GGCCGCCGAT 
CCCAAGATTG TGAACAAATT CAAGGCCGGA TTCGCCGACT GTGTGAACGA GGTTAGCCGC 
TTTCCCGGCA TCGAGCCCGC CCAGCGTCGT CGCCTGCTAC AGCACCTGAG CAACTGCATC 
AATGGCGTTA AGACAGAGCT GCACCAGCAG CAGCGCCAGC AGCAACAGCA GTCCATCCAC 
GCCCAGATGC TGCCCTCGCC GCCCAGCTCG CCGGAGCAGG ATAGCCAGCA GGGAGCAGCG 
GCACCCTACC TCTTTGGTAT CCAGCAGACG GCCAGCGGTT ACTTTCTGCC CAATGGCATG 
CAGGTGATCC CCACCAAGCT GCCCAACGGT AGCATTGCCC TCGTGTTGCC CCAGAGCCTG 
CCCCAGCAGC AGCAGCAACA GTTGCTGCAG CACCAACAGC AGCAGCAGCA ACTCGCCGTC 
GCAGCAGCAG CAGCGGCCGC AGCAGCAGCA CAACAGCAAC CCATGTTGGT CAGCATGCCC 
CAGCGTACAG CCAGCACCGG ATCCGCCAGC TCGCACTCCT CCGCCGGATA CGAGTCGGCG 
CCCGGAAGCA GCAGCAGCTG TAGCTACGCC CCGCCCAGTC CGGCCAACTC TAGCTACGAG 
CCCATGGACA TCAAGCCATC GGTCATCCAG CGCGTGCCAA TGGAGCAGCA GCCCCTGTCG 
CTGGTGATCA AGAAGCAGAT CAAGGAGGAG GAGCAGCCCT GGCGGCCCTG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

h ( NM_079253.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_523977.2 Drosophila melanogaster hairy (h), transcript variant A, mRNA.

Price & Availability↑

CloneID	OFa17929
Clone ID Related Accession (Same CDS sequence)	NM_001014577.2 , NM_079253.4
Accession Version	NM_079253.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	hairy, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_079253.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGTTACCG GCGTAACAGC AGCCAACATG ACCAACGTTC TGGGCACCGC CGTTGTGCCG 
GCCCAGCTCA AGGAGACGCC GCTCAAAAGT GACCGTCGGT CGAACAAGCC CATCATGGAG 
AAACGCCGAC GTGCCCGTAT TAACAACTGT CTCAATGAAC TCAAGACTCT GATTCTGGAT 
GCCACCAAAA AAGACCCGGC TCGCCACTCC AAATTGGAAA AGGCCGACAT TCTGGAGAAG 
ACAGTAAAGC ATCTGCAGGA GCTGCAGCGC CAGCAGGCAG CCATGCAGCA GGCCGCCGAT 
CCCAAGATTG TGAACAAATT CAAGGCCGGA TTCGCCGACT GTGTGAACGA GGTTAGCCGC 
TTTCCCGGCA TCGAGCCCGC CCAGCGTCGT CGCCTGCTAC AGCACCTGAG CAACTGCATC 
AATGGCGTTA AGACAGAGCT GCACCAGCAG CAGCGCCAGC AGCAACAGCA GTCCATCCAC 
GCCCAGATGC TGCCCTCGCC GCCCAGCTCG CCGGAGCAGG ATAGCCAGCA GGGAGCAGCG 
GCACCCTACC TCTTTGGTAT CCAGCAGACG GCCAGCGGTT ACTTTCTGCC CAATGGCATG 
CAGGTGATCC CCACCAAGCT GCCCAACGGT AGCATTGCCC TCGTGTTGCC CCAGAGCCTG 
CCCCAGCAGC AGCAGCAACA GTTGCTGCAG CACCAACAGC AGCAGCAGCA ACTCGCCGTC 
GCAGCAGCAG CAGCGGCCGC AGCAGCAGCA CAACAGCAAC CCATGTTGGT CAGCATGCCC 
CAGCGTACAG CCAGCACCGG ATCCGCCAGC TCGCACTCCT CCGCCGGATA CGAGTCGGCG 
CCCGGAAGCA GCAGCAGCTG TAGCTACGCC CCGCCCAGTC CGGCCAACTC TAGCTACGAG 
CCCATGGACA TCAAGCCATC GGTCATCCAG CGCGTGCCAA TGGAGCAGCA GCCCCTGTCG 
CTGGTGATCA AGAAGCAGAT CAAGGAGGAG GAGCAGCCCT GGCGGCCCTG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_523977.2
CDS	296..1309
Translation	MVTGVTAANMTNVLGTAVVPAQLKETPLKSDRRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQQAAMQQAADPKIVNKFKAGFADCVNEVSRFPGIEPAQRRRLLQHLSNCINGVKTELHQQQRQQQQQSIHAQMLPSPPSSPEQDSQQGAAAPYLFGIQQTASGYFLPNGMQVIPTKLPNGSIALVLPQSLPQQQQQQLLQHQQQQQQLAVAAAAAAAAAAQQQPMLVSMPQRTASTGSASSHSSAGYESAPGSSSSCSYAPPSPANSSYEPMDIKPSVIQRVPMEQQPLSLVIKKQIKEEEQPWRPW

Target ORF information:

RefSeq Version	NM_079253.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster hairy (h), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079253.4

ORF Insert Sequence:

ATGGTTACCG GCGTAACAGC AGCCAACATG ACCAACGTTC TGGGCACCGC CGTTGTGCCG 
GCCCAGCTCA AGGAGACGCC GCTCAAAAGT GACCGTCGGT CGAACAAGCC CATCATGGAG 
AAACGCCGAC GTGCCCGTAT TAACAACTGT CTCAATGAAC TCAAGACTCT GATTCTGGAT 
GCCACCAAAA AAGACCCGGC TCGCCACTCC AAATTGGAAA AGGCCGACAT TCTGGAGAAG 
ACAGTAAAGC ATCTGCAGGA GCTGCAGCGC CAGCAGGCAG CCATGCAGCA GGCCGCCGAT 
CCCAAGATTG TGAACAAATT CAAGGCCGGA TTCGCCGACT GTGTGAACGA GGTTAGCCGC 
TTTCCCGGCA TCGAGCCCGC CCAGCGTCGT CGCCTGCTAC AGCACCTGAG CAACTGCATC 
AATGGCGTTA AGACAGAGCT GCACCAGCAG CAGCGCCAGC AGCAACAGCA GTCCATCCAC 
GCCCAGATGC TGCCCTCGCC GCCCAGCTCG CCGGAGCAGG ATAGCCAGCA GGGAGCAGCG 
GCACCCTACC TCTTTGGTAT CCAGCAGACG GCCAGCGGTT ACTTTCTGCC CAATGGCATG 
CAGGTGATCC CCACCAAGCT GCCCAACGGT AGCATTGCCC TCGTGTTGCC CCAGAGCCTG 
CCCCAGCAGC AGCAGCAACA GTTGCTGCAG CACCAACAGC AGCAGCAGCA ACTCGCCGTC 
GCAGCAGCAG CAGCGGCCGC AGCAGCAGCA CAACAGCAAC CCATGTTGGT CAGCATGCCC 
CAGCGTACAG CCAGCACCGG ATCCGCCAGC TCGCACTCCT CCGCCGGATA CGAGTCGGCG 
CCCGGAAGCA GCAGCAGCTG TAGCTACGCC CCGCCCAGTC CGGCCAACTC TAGCTACGAG 
CCCATGGACA TCAAGCCATC GGTCATCCAG CGCGTGCCAA TGGAGCAGCA GCCCCTGTCG 
CTGGTGATCA AGAAGCAGAT CAAGGAGGAG GAGCAGCCCT GGCGGCCCTG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

h cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報