lin-52 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	lin-52
Entrez Gene ID	31499
Full Name	CG15929 gene product from transcript CG15929-RB
Synonyms	CG15929,Dmel\CG15929,Lin-52,Lin52,dLIN-52,dLin-52,dLin52,dlin-52,dlin52
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: X Map Location: 5B6-5B7

mRNA and Protein(s)

mRNA	Protein	Name
NM_132028.3	NP_572256.1	lin-52, isoform A
NM_001297979.1	NP_001284908.1	lin-52, isoform B

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

conclude that dLin52 functions as a co-factor and modulates activity of members of dMyb/dREAM complex at hid promoter, thus regulating apoptosis by repressing this pro-apoptotic gene in the developing Drosophila eye
Title: dLin52 is crucial for dE2F and dRBF mediated transcriptional regulation of pro-apoptotic gene hid.

the Lin-52 and Myb proteins counteract the repressive activities of the other members of the MMB/dREAM complex at specific genomic loci in a developmentally controlled manner
Title: Drosophila lin-52 acts in opposition to repressive components of the Myb-MuvB/dREAM complex.

dlin52 is expressed in the larval optic lobe, as well as in the developing neurons of ventral ganglion, indicating that this gene has an important role to play in cell cycle regulation and neuronal development.
Title: Dynamic pattern of expression of dlin52, a member of the Myb/MuvB complex, during Drosophila development.

The following lin-52 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lin-52 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa00889	NM_001297979.1 Latest version!	Drosophila melanogaster lin-52, transcript variant B (lin-52), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa00889	NM_132028.3 Latest version!	Drosophila melanogaster lin-52, transcript variant A (lin-52), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

lin-52 ( NM_132028.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_572256.1 Drosophila melanogaster lin-52, transcript variant A (lin-52), mRNA.

Price & Availability↑

CloneID	OFa00889
Clone ID Related Accession (Same CDS sequence)	NM_132028.3 , NM_001297979.1
Accession Version	NM_132028.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 474bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	lin-52, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_132028.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAGCAACG CAGAGACAAC TACGGATTTG CTTTCTACAG AAACCATTCT AAAAGCGGCG 
GACGAGGAAG TGGAGAAGGC TTCAGCGTCC AGCAGTAGTA CGTTATTGGC CGAAAAGGAT 
GTCCCGGAGG TCAAGGAGCG GCCCATAACG CCGGAAGACG AGCTCATCTC CATGGAAACT 
CTGCGACCCT CACCTGTCCA ATGGCCAGAG CGTTTTCCCG GAATGGACGA GTTCCTCTCC 
ATGAGCGACA CGCCGATGTA CACGCGCAGC ACCAACTACA CCAGCAATCT GACCGATGAT 
GATATGGTTA AGATTAATGA ACTAGCCCAG CTCCCTCCCG AGGATCTGAT CGATAAAATA 
AAGTCAATGC ATGATGAAAT TTACCAGCTG GGACTGCGTG AGGCAATGGA GATGACTCGT 
GGGAAACTGC TGGGCATCTT TGACCGGGAT CGCGCTCCTA AGCGGCAGCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_572256.1
CDS	75..548
Translation	MSNAETTTDLLSTETILKAADEEVEKASASSSSTLLAEKDVPEVKERPITPEDELISMETLRPSPVQWPERFPGMDEFLSMSDTPMYTRSTNYTSNLTDDDMVKINELAQLPPEDLIDKIKSMHDEIYQLGLREAMEMTRGKLLGIFDRDRAPKRQP

Target ORF information:

RefSeq Version	NM_132028.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster lin-52, transcript variant A (lin-52), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_132028.3

ORF Insert Sequence:

ATGAGCAACG CAGAGACAAC TACGGATTTG CTTTCTACAG AAACCATTCT AAAAGCGGCG 
GACGAGGAAG TGGAGAAGGC TTCAGCGTCC AGCAGTAGTA CGTTATTGGC CGAAAAGGAT 
GTCCCGGAGG TCAAGGAGCG GCCCATAACG CCGGAAGACG AGCTCATCTC CATGGAAACT 
CTGCGACCCT CACCTGTCCA ATGGCCAGAG CGTTTTCCCG GAATGGACGA GTTCCTCTCC 
ATGAGCGACA CGCCGATGTA CACGCGCAGC ACCAACTACA CCAGCAATCT GACCGATGAT 
GATATGGTTA AGATTAATGA ACTAGCCCAG CTCCCTCCCG AGGATCTGAT CGATAAAATA 
AAGTCAATGC ATGATGAAAT TTACCAGCTG GGACTGCGTG AGGCAATGGA GATGACTCGT 
GGGAAACTGC TGGGCATCTT TGACCGGGAT CGCGCTCCTA AGCGGCAGCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

lin-52 ( NM_001297979.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001284908.1 Drosophila melanogaster lin-52, transcript variant B (lin-52), mRNA.

Price & Availability↑

CloneID	OFa00889
Clone ID Related Accession (Same CDS sequence)	NM_132028.3 , NM_001297979.1
Accession Version	NM_001297979.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 474bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	lin-52, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAGCAACG CAGAGACAAC TACGGATTTG CTTTCTACAG AAACCATTCT AAAAGCGGCG 
GACGAGGAAG TGGAGAAGGC TTCAGCGTCC AGCAGTAGTA CGTTATTGGC CGAAAAGGAT 
GTCCCGGAGG TCAAGGAGCG GCCCATAACG CCGGAAGACG AGCTCATCTC CATGGAAACT 
CTGCGACCCT CACCTGTCCA ATGGCCAGAG CGTTTTCCCG GAATGGACGA GTTCCTCTCC 
ATGAGCGACA CGCCGATGTA CACGCGCAGC ACCAACTACA CCAGCAATCT GACCGATGAT 
GATATGGTTA AGATTAATGA ACTAGCCCAG CTCCCTCCCG AGGATCTGAT CGATAAAATA 
AAGTCAATGC ATGATGAAAT TTACCAGCTG GGACTGCGTG AGGCAATGGA GATGACTCGT 
GGGAAACTGC TGGGCATCTT TGACCGGGAT CGCGCTCCTA AGCGGCAGCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001284908.1
CDS	75..548
Translation	MSNAETTTDLLSTETILKAADEEVEKASASSSSTLLAEKDVPEVKERPITPEDELISMETLRPSPVQWPERFPGMDEFLSMSDTPMYTRSTNYTSNLTDDDMVKINELAQLPPEDLIDKIKSMHDEIYQLGLREAMEMTRGKLLGIFDRDRAPKRQP

Target ORF information:

RefSeq Version	NM_001297979.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster lin-52, transcript variant B (lin-52), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001297979.1

ORF Insert Sequence:

ATGAGCAACG CAGAGACAAC TACGGATTTG CTTTCTACAG AAACCATTCT AAAAGCGGCG 
GACGAGGAAG TGGAGAAGGC TTCAGCGTCC AGCAGTAGTA CGTTATTGGC CGAAAAGGAT 
GTCCCGGAGG TCAAGGAGCG GCCCATAACG CCGGAAGACG AGCTCATCTC CATGGAAACT 
CTGCGACCCT CACCTGTCCA ATGGCCAGAG CGTTTTCCCG GAATGGACGA GTTCCTCTCC 
ATGAGCGACA CGCCGATGTA CACGCGCAGC ACCAACTACA CCAGCAATCT GACCGATGAT 
GATATGGTTA AGATTAATGA ACTAGCCCAG CTCCCTCCCG AGGATCTGAT CGATAAAATA 
AAGTCAATGC ATGATGAAAT TTACCAGCTG GGACTGCGTG AGGCAATGGA GATGACTCGT 
GGGAAACTGC TGGGCATCTT TGACCGGGAT CGCGCTCCTA AGCGGCAGCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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lin-52 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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