alx1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	alx1
Entrez Gene ID	565176
Full Name	ALX homeobox 1
Synonyms	CART-1,cart1,si:ch211-154h20.1
General protein information	Preferred Names ALX homeobox 1 Names ALX homeobox protein 1 cartilage paired-class homeoprotein 1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001045074.1	NP_001038539.1	ALX homeobox protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ALX1	NP_008913.2
Gallus gallus (chicken)	ALX1	XP_425445.3
Rattus norvegicus (Norway rat)	Alx1	NP_037053.1
Xenopus tropicalis (tropical clawed frog)	alx1	XP_002931669.1
Bos taurus (cattle)	ALX1	NP_001179220.1
Mus musculus (house mouse)	Alx1	NP_766141.1
Danio rerio (zebrafish)	alx1	NP_001038539.1
Pan troglodytes (chimpanzee)	ALX1	XP_509250.2
Canis lupus familiaris (dog)	ALX1	XP_005629485.1

Gene Ontology
Bibliography

Related articles in PubMed

Essential Role of Nr2f Nuclear Receptors in Patterning the Vertebrate Upper Jaw.
Barske L, Rataud P, Behizad K, Del Rio L, Cox SG, Crump JG
Developmental cell(2018 Jan)

Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis.
Sedykh I, Yoon B, Roberson L, Moskvin O, Dewey CN, Grinblat Y
Developmental biology429(1)92-104(2017 09)

Phenotypic chemical screening using a zebrafish neural crest EMT reporter identifies retinoic acid as an inhibitor of epithelial morphogenesis.
Jimenez L, Wang J, Morrison MA, Whatcott C, Soh KK, Warner S, Bearss D, Jette CA, Stewart RA
Disease models & mechanisms9(4)389-400(2016 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Alx1 plays a crucial role in regulating the migration of cranial neural crest (CNC) cells into the frontonasal primordia.
Title: Defective neural crest migration revealed by a Zebrafish model of Alx1-related frontonasal dysplasia.

The following alx1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the alx1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01638	NM_001045074.1 Latest version!	Danio rerio ALX homeobox 1 (alx1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

alx1 ( NM_001045074.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001038539.1 Danio rerio ALX homeobox 1 (alx1), mRNA.

Price & Availability↑

CloneID	ODa01638
Clone ID Related Accession (Same CDS sequence)	NM_001045074.1
Accession Version	NM_001045074.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 963bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Danio rerio(zebrafish)
Product	ALX homeobox protein 1
Comment	Comment: INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from BX000347.7. On Sep 1, 2006 this sequence version replaced XM_688461.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTATT TGAGCGACAA GTTCTCCTTG AAAAGTCCAG CGATTAAAGG CAGCGATTAC 
TACATGGACC AAGTCATGGA TACTTTAGAT AATGTGCAGT ACTACAACAA GGCATCGCCG 
AAATGCGTCC AAGCATTCCC GATGCAGAGC AATGACCAGC ACTCCTCCAT GGACAGATCG 
TCTCCGTGCG ATAACCAAAG CAGCGTGACT TACTGCGCTC CTAAATCTGA GGAGAGCAGC 
CTGCACGCGA TGGAAAACTG CTGCAGCCTC AGGGTCTCAC CGGCCACAAG CGGACCCGAC 
AAAACAGACC TCGACGAACT CGGAGAAAAA TGCGACAGCA ACGTGTCGAG CAGCAAGAAG 
AGACGCCACC GCACAACCTT CACGAGTGCT CAGCTGGAGG AGCTGGAGAA AGTCTTCCAG 
AAAACCCATT ATCCAGATGT GTACGTGAGA GAGCAGCTGG CCATGCGGAC AGAGCTCACG 
GAGGCCCGGG TTCAGGTTTG GTTCCAAAAC AGAAGAGCTA AGTGGAGGAA GAGAGAAAGA 
TATGGACAAA TACAGCAGGC CAAAAGTCAT TTTGCAGCAA CTTATGACAT CTCAATGCTG 
CCACGGACAG ACAGCTACTC ACAGATCTCC AATAACCTAT GGACAGGGCC GAGCGCGGGC 
AGCTCAGTGG TGTCGTCCTG CATGATCCCC CGAGGGTCCC CACCCTGCGT CACATCCCCG 
TACCCACATT CACCCAGAGC CGCGGAGCAT GGCTATGTGG GATTCCCAAA CCACCAGCAA 
AATCAGTTCG GAGTCAATCA TGTTTCCCTC AACAACTTCT TTGCTGATTC TCTTCTGGCT 
TCGTCAGCGA ACAGTCACGC CGCGTTTGAG ACCAAACCGG AGTTCGAGCG CCGCTCCTCC 
AGCATTGCTG TACTGCGAAT GAAGGCCAAA GAACACACAG CCAACATCTC CTGGGCTATG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001038539.1
CDS	1..963
Translation	MEYLSDKFSLKSPAIKGSDYYMDQVMDTLDNVQYYNKASPKCVQAFPMQSNDQHSSMDRSSPCDNQSSVTYCAPKSEESSLHAMENCCSLRVSPATSGPDKTDLDELGEKCDSNVSSSKKRRHRTTFTSAQLEELEKVFQKTHYPDVYVREQLAMRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISMLPRTDSYSQISNNLWTGPSAGSSVVSSCMIPRGSPPCVTSPYPHSPRAAEHGYVGFPNHQQNQFGVNHVSLNNFFADSLLASSANSHAAFETKPEFERRSSSIAVLRMKAKEHTANISWAM

Target ORF information:

RefSeq Version	NM_001045074.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio ALX homeobox 1 (alx1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001045074.1

ORF Insert Sequence:

ATGGAGTATT TGAGCGACAA GTTCTCCTTG AAAAGTCCAG CGATTAAAGG CAGCGATTAC 
TACATGGACC AAGTCATGGA TACTTTAGAT AATGTGCAGT ACTACAACAA GGCATCGCCG 
AAATGCGTCC AAGCATTCCC GATGCAGAGC AATGACCAGC ACTCCTCCAT GGACAGATCG 
TCTCCGTGCG ATAACCAAAG CAGCGTGACT TACTGCGCTC CTAAATCTGA GGAGAGCAGC 
CTGCACGCGA TGGAAAACTG CTGCAGCCTC AGGGTCTCAC CGGCCACAAG CGGACCCGAC 
AAAACAGACC TCGACGAACT CGGAGAAAAA TGCGACAGCA ACGTGTCGAG CAGCAAGAAG 
AGACGCCACC GCACAACCTT CACGAGTGCT CAGCTGGAGG AGCTGGAGAA AGTCTTCCAG 
AAAACCCATT ATCCAGATGT GTACGTGAGA GAGCAGCTGG CCATGCGGAC AGAGCTCACG 
GAGGCCCGGG TTCAGGTTTG GTTCCAAAAC AGAAGAGCTA AGTGGAGGAA GAGAGAAAGA 
TATGGACAAA TACAGCAGGC CAAAAGTCAT TTTGCAGCAA CTTATGACAT CTCAATGCTG 
CCACGGACAG ACAGCTACTC ACAGATCTCC AATAACCTAT GGACAGGGCC GAGCGCGGGC 
AGCTCAGTGG TGTCGTCCTG CATGATCCCC CGAGGGTCCC CACCCTGCGT CACATCCCCG 
TACCCACATT CACCCAGAGC CGCGGAGCAT GGCTATGTGG GATTCCCAAA CCACCAGCAA 
AATCAGTTCG GAGTCAATCA TGTTTCCCTC AACAACTTCT TTGCTGATTC TCTTCTGGCT 
TCGTCAGCGA ACAGTCACGC CGCGTTTGAG ACCAAACCGG AGTTCGAGCG CCGCTCCTCC 
AGCATTGCTG TACTGCGAAT GAAGGCCAAA GAACACACAG CCAACATCTC CTGGGCTATG 
TGA