Gene Symbol | unc-51 |
Entrez Gene ID | 180311 |
Full Name | Serine/threonine-protein kinase unc-51 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » unc-51 cDNA ORF clone
Gene Symbol | unc-51 |
Entrez Gene ID | 180311 |
Full Name | Serine/threonine-protein kinase unc-51 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_075468.4 | NP_507869.1 | Serine/threonine-protein kinase unc-51 |
NM_075468.5 | NP_507869.1 | Serine/threonine-protein kinase unc-51 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
PP2A cooperates with UNC-51 to regulate axon guidance by regulating phosphorylation.
Title: Protein phosphatase 2A cooperates with the autophagy-related kinase UNC-51 to regulate axon guidance in Caenorhabditis elegans.
Inactivation of unc-51, bec-1 and lgg-1, the worm counterparts of the yeast autophagy genes Atg1, Atg6 and Atg8 respectively, partially suppresses degeneration of neurons with toxic ion channel variants.
Title: Influence of autophagy genes on ion-channel-dependent neuronal degeneration in Caenorhabditis elegans.
The autophagy-related kinase UNC-51 regulates the subcellular localization of the Netrin receptor UNC-5 in Caenorhabditis elegans
Title: The autophagy-related kinase UNC-51 and its binding partner UNC-14 regulate the subcellular localization of the Netrin receptor UNC-5 in Caenorhabditis elegans.
VAB-8 and UNC-14 are substrates that mediate the function of UNC-51 in axon outgrowth
Title: The conserved kinase UNC-51 acts with VAB-8 and UNC-14 to regulate axon outgrowth in C. elegans.
Mutants with impaired growth cone functions, such as unc-51, often exhibit abnormal terminations and inappropriate trajectories at the distal ends of the M2 axons.
Title: A genetic analysis of axon guidance in the C elegans pharynx.
The following unc-51 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the unc-51 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa346633 | |
Clone ID Related Accession (Same CDS sequence) | NM_075468.4 , NM_075468.5 | |
Accession Version | NM_075468.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2571bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Serine/threonine-protein kinase unc-51 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_075468.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGAGCAGT TTGACGGCTT CGAGTACAGC AAACGGGACC TTTTAGGTCA TGGAGCATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_507869.1 |
CDS | 1..2571 |
Translation |
Target ORF information:
Target ORF information:
|
NM_075468.4 |
1 | ATGGAGCAGT TTGACGGCTT CGAGTACAGC AAACGGGACC TTTTAGGTCA TGGAGCATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346633 | |
Clone ID Related Accession (Same CDS sequence) | NM_075468.4 , NM_075468.5 | |
Accession Version | NM_075468.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2571bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Serine/threonine-protein kinase unc-51 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_075468.4. |
1 | ATGGAGCAGT TTGACGGCTT CGAGTACAGC AAACGGGACC TTTTAGGTCA TGGAGCATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_507869.1 |
CDS | 66..2636 |
Translation |
Target ORF information:
Target ORF information:
|
NM_075468.5 |
1 | ATGGAGCAGT TTGACGGCTT CGAGTACAGC AAACGGGACC TTTTAGGTCA TGGAGCATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |