Gene Symbol | hda-1 |
Entrez Gene ID | 179959 |
Full Name | Histone deacetylase 1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » hda-1 cDNA ORF clone
Gene Symbol | hda-1 |
Entrez Gene ID | 179959 |
Full Name | Histone deacetylase 1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_074198.7 | NP_506599.1 | Histone deacetylase 1 |
NM_074198.8 | NP_506599.1 | Histone deacetylase 1 |
Pan troglodytes (chimpanzee) | HDAC2 | XP_518700.2 |
Oryza sativa (rice) | Os08g0344100 | NP_001061596.1 |
Bos taurus (cattle) | HDAC2 | NP_001068614.1 |
Arabidopsis thaliana (thale cress) | HDA6 | NP_201116.1 |
Xenopus tropicalis (tropical clawed frog) | hdac2 | NP_001005432.1 |
Canis lupus familiaris (dog) | HDAC2 | XP_532270.4 |
Mus musculus (house mouse) | Hdac2 | NP_032255.2 |
Danio rerio (zebrafish) | hdac1 | NP_775343.1 |
Homo sapiens (human) | HDAC2 | NP_001518.3 |
Rattus norvegicus (Norway rat) | Hdac2 | NP_445899.1 |
Gallus gallus (chicken) | HDAC2 | NP_990162.1 |
Caenorhabditis elegans (roundworm) | hda-1 | NP_506599.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We further show that G1 arrest is necessary for the histone deacetylase HDA-1, a key regulator of differentiation, to promote pro-invasive gene expression and invadopodia formation.
Title: Invasive Cell Fate Requires G1 Cell-Cycle Arrest and Histone Deacetylase-Mediated Changes in Gene Expression.
hda-1 target genes revealed that fos-1 acts downstream of hda-1 in vulval cells, whereas egl-43 and nhr-67 mediate hda-1 function in the gonadal anchor cell.
Title: Caenorhabditis elegans histone deacetylase hda-1 is required for morphogenesis of the vulva and LIN-12/Notch-mediated specification of uterine cell fates.
HDAC behaves as a co-repressor modulating FOS-1-mediated transcriptional regulation
Title: The Caenorhabditis elegans JNK signaling pathway activates expression of stress response genes by derepressing the Fos/HDAC repressor complex.
Theses studies define a new role for HDA-1 in nervous system development, and provide the first evidence for HDAC function in regulating neuronal axon guidance.
Title: The C. elegans histone deacetylase HDA-1 is required for cell migration and axon pathfinding.
The following hda-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hda-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa345783 | |
Clone ID Related Accession (Same CDS sequence) | NM_074198.7 , NM_074198.8 | |
Accession Version | NM_074198.7 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Histone deacetylase 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_074198.6. COMPLETENESS: incomplete on both ends. |
1 | ATGAACTCAA ACGGCCCGTT GATGGAGCAC GGTAAGCGCC GTGTCGCCTA CTACTATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_506599.1 |
CDS | 1..1386 |
Translation |
Target ORF information:
Target ORF information:
|
NM_074198.7 |
1 | ATGAACTCAA ACGGCCCGTT GATGGAGCAC GGTAAGCGCC GTGTCGCCTA CTACTATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa345783 | |
Clone ID Related Accession (Same CDS sequence) | NM_074198.7 , NM_074198.8 | |
Accession Version | NM_074198.8 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Histone deacetylase 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_074198.7. |
1 | ATGAACTCAA ACGGCCCGTT GATGGAGCAC GGTAAGCGCC GTGTCGCCTA CTACTATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_506599.1 |
CDS | 20..1405 |
Translation |
Target ORF information:
Target ORF information:
|
NM_074198.8 |
1 | ATGAACTCAA ACGGCCCGTT GATGGAGCAC GGTAAGCGCC GTGTCGCCTA CTACTATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |