Hdac2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Histone deacetylase 2 is involved in ??opioid receptor suppression in the spinal dorsal horn in a rat model of chronic pancreatitis pain.
Liao YH, Wang J, Wei YY, Zhang T, Zhang Y, Zuo ZF, Teng XY, Li YQ
Molecular medicine reports17(2)2803-2810(2018 Feb)

Selective inhibition of HDAC2 by magnesium valproate attenuates cardiac hypertrophy.
Raghunathan S, Goyal RK, Patel BM
Canadian journal of physiology and pharmacology95(3)260-267(2017 Mar)

Selective inhibition of HDAC2 by magnesium valproate attenuates cardiac hypertrophy.
Title: Selective inhibition of HDAC2 by magnesium valproate attenuates cardiac hypertrophy.

revealed a complex pattern of expression of spinal HDAC2 that depends on the injury and the cell type, suggesting a sophisticated regulation of gene expression by HDAC2
Title: Complex regulation of the regulator of synaptic plasticity histone deacetylase 2 in the rodent dorsal horn after peripheral injury.

HDAC2 deletion in BMMs resulted in decreased Akt activation and increased FoxO1 activity during osteoclastogenesis. In conclusion, HDAC2 activates Akt thus suppresses FoxO1 transcription results in enhanced osteoclastogenesis. Our data imply the potential value of HDAC2 as a new target in regulating osteoclast differentiation and function.
Title: HDAC2 regulates FoxO1 during RANKL-induced osteoclastogenesis.

HDAC2 might be a downstream effector of Jak2 to mediate cardiac hypertrophic response by pressure overload or Ang-II.
Title: Pressure overload-induced cardiac hypertrophy response requires janus kinase 2-histone deacetylase 2 signaling.

Using genome-wide analysis study shows that histone deacetylase (HDAC)2 and HDAC3 show overlapping and distinct promoter occupancy at neuronal and oligodendrocyte-related genes in neural stem cells.
Title: Neural stem cell differentiation is dictated by distinct actions of nuclear receptor corepressors and histone deacetylases.