Gene Symbol | gpr-2 |
Entrez Gene ID | 176318 |
Full Name | G-protein regulator 2 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » gpr-2 cDNA ORF clone
Gene Symbol | gpr-2 |
Entrez Gene ID | 176318 |
Full Name | G-protein regulator 2 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_066665.6 | NP_499066.1 | G-protein regulator 2 |
NM_066665.5 | NP_499066.1 | G-protein regulator 2 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Four distinct in vivo phosphorylated LIN-5 residues were found to have critical functions in spindle positioning. Two of these residues form part of a 30 amino acid binding site for GPR-1, which we identified by reverse two-hybrid screening. These LIN-5 phosphorylations promote LIN-5-GPR-1/2 interaction and contribute to cortical pulling forces
Title: Multisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegans.
Data demonstrate that GPB-1 depletion results in the loss of GPR-1/2 asymmetry during mitosis.
Title: Polarity mediates asymmetric trafficking of the Gbeta heterotrimeric G-protein subunit GPB-1 in C. elegans embryos.
Dynamic localization of gpr-2 to cell cortex forces generation of domains during spindle positioning.
Title: Dynamic localization of LIN-5 and GPR-1/2 to cortical force generation domains during spindle positioning.
Data suggest a mechanism in which RIC-8 favors generation of Galpha free from Gbetagamma and enables GPR-1/2 to mediate asymmetric cell division.
Title: RIC-8 is required for GPR-1/2-dependent Galpha function during asymmetric division of C. elegans embryos.
findings show that the GoLoco-containing proteins GPR-1 and GPR-2, as well as the Galpha subunits GOA-1 and GPA-16, were essential for generation of proper pulling forces in asymmetric spindle positioning
Title: Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos.
The following gpr-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the gpr-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa341778 | |
Clone ID Related Accession (Same CDS sequence) | NM_066665.6 , NM_066665.5 | |
Accession Version | NM_066665.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1578bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | G-protein regulator 2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_066665.5. |
1 | ATGGACGTCT CTTATTATGA TGGCCCTAAG GATGAAGTCA TCGAAGCAAT GCTGAAAAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499066.1 |
CDS | 24..1601 |
Translation |
Target ORF information:
Target ORF information:
|
NM_066665.6 |
1 | ATGGACGTCT CTTATTATGA TGGCCCTAAG GATGAAGTCA TCGAAGCAAT GCTGAAAAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341778 | |
Clone ID Related Accession (Same CDS sequence) | NM_066665.6 , NM_066665.5 | |
Accession Version | NM_066665.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1578bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | G-protein regulator 2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_066665.4. COMPLETENESS: incomplete on both ends. |
1 | ATGGACGTCT CTTATTATGA TGGCCCTAAG GATGAAGTCA TCGAAGCAAT GCTGAAAAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499066.1 |
CDS | 1..1578 |
Translation |
Target ORF information:
Target ORF information:
|
NM_066665.5 |
1 | ATGGACGTCT CTTATTATGA TGGCCCTAAG GATGAAGTCA TCGAAGCAAT GCTGAAAAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |