TLR1 cDNA ORF clone, Bos taurus(cattle)

Epithelial and stromal cells of bovine endometrium have roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides in vitro via Toll-like receptors TLR2, TLR1, and TLR6.
Turner ML, Cronin JG, Healey GD, Sheldon IM
Endocrinology155(4)1453-65(2014 Apr)

Polymorphisms in toll-like receptor 1 and 9 genes and their association with tuberculosis susceptibility in Chinese Holstein cattle.
Sun L, Song Y, Riaz H, Yang H, Hua G, Guo A, Yang L
Veterinary immunology and immunopathology147(3-4)195-201(2012 Jun)

Identification of single nucleotide polymorphisms in the bovine Toll-like receptor 1 gene and association with health traits in cattle.
Russell CD, Widdison S, Leigh JA, Coffey TJ
Veterinary research4317(2012 Mar)

Genetic variation of toll-like receptor genes and infection by Mycobacterium avium ssp. paratuberculosis in Holstein-Friesian cattle.
Ruiz-Larra?aga O, Manzano C, Iriondo M, Garrido JM, Molina E, Vazquez P, Juste RA, Estonba A
Journal of dairy science94(7)3635-41(2011 Jul)

TLR2, TLR1, and TLR6 haev roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides by epithelial and stromal cells of bovine endometrium
Title: Epithelial and stromal cells of bovine endometrium have roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides in vitro via Toll-like receptors TLR2, TLR1, and TLR6.

variants in the TLR1 gene are associated with susceptibility to bovine tuberculosis, whereas no significant association can be inferred from the polymorphisms in the TLR9 gene
Title: Polymorphisms in toll-like receptor 1 and 9 genes and their association with tuberculosis susceptibility in Chinese Holstein cattle.

There is an association between single nucleotide polymorphisms (SNPs), common to boTLR1, and clinical mastitis susceptibility. Furthermore, some of these SNPs underpin functional variation in boTLR1.
Title: Identification of single nucleotide polymorphisms in the bovine Toll-like receptor 1 gene and association with health traits in cattle.

Whereas previous results regarding the TLR1 gene were not corroborated, a risk haplotype was detected in TLR2; however, its low frequency indicates that this detected association should be interpreted with caution.
Title: Genetic variation of toll-like receptor genes and infection by Mycobacterium avium ssp. paratuberculosis in Holstein-Friesian cattle.

This study showed that TLR1 and TLR2 together are necessary for the recognition of triacylated lipopeptides.
Title: Identification of full length bovine TLR1 and functional characterization of lipopeptide recognition by bovine TLR2/1 heterodimer.