PGRMC2 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	PGRMC2
Entrez Gene ID	534021
Full Name	progesterone receptor membrane component 2
Synonyms	PMBP
General protein information	Preferred Names progesterone receptor membrane component 2 Names membrane-associated progesterone receptor component 2 progesterone membrane binding protein
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001099060.1	NP_001092530.1	membrane-associated progesterone receptor component 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	PGRMC2	NP_006311.2
Gallus gallus (chicken)	PGRMC2	NP_001006441.1
Xenopus tropicalis (tropical clawed frog)	pgrmc2	XP_002932101.2
Pan troglodytes (chimpanzee)	PGRMC2	XP_517434.2
Mus musculus (house mouse)	Pgrmc2	NP_081834.1
Danio rerio (zebrafish)	pgrmc2	NP_998269.1
Bos taurus (cattle)	PGRMC2	NP_001092530.1
Canis lupus familiaris (dog)	PGRMC2	XP_005631865.1
	PGRMC2	XP_001082791.1
Rattus norvegicus (Norway rat)	Pgrmc2	NP_001008375.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression and localization of progesterone receptor membrane component 1 and 2 and serpine mRNA binding protein 1 in the bovine corpus luteum during the estrous cycle and the first trimester of pregnancy.
Kowalik MK, Rekawiecki R, Kotwica J
Theriogenology82(8)1086-93(2014 Nov)

Expression of progesterone receptor membrane component (PGRMC) 1 and 2, serpine mRNA binding protein 1 (SERBP1) and nuclear progesterone receptor (PGR) in the bovine endometrium during the estrous cycle and the first trimester of pregnancy.
Kowalik MK, Slonina D, Rekawiecki R, Kotwica J
Reproductive biology13(1)15-23(2013 Mar)

Expression of nuclear progesterone receptor and progesterone receptor membrane components 1 and 2 in the oviduct of cyclic and pregnant cows during the post-ovulation period.
Saint-Dizier M, Sandra O, Ployart S, Chebrout M, Constant F
Reproductive biology and endocrinology : RB&E1076(2012 Sep)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Isolation and characterization of hepatic and intestinal expressed sequence tags potentially involved in trait differentiation between cows of different metabolic type.
Dorroch U, Goldammer T, Brunner RM, Kata SR, K?hn C, Womack JE, Schwerin M
Mammalian genome : official journal of the International Mammalian Genome Society12(7)528-37(2001 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data indicate variable expression of progesterone receptor membrane component 1 and 2 and serpine mRNA binding protein 1 mRNA and protein in bovine corpus luteum and suggest that progesterone may regulate corpus luteum function via its membrane receptors
Title: Expression and localization of progesterone receptor membrane component 1 and 2 and serpine mRNA binding protein 1 in the bovine corpus luteum during the estrous cycle and the first trimester of pregnancy.

endometrial mRNA level elevated during pregnancy is unchanged during estrous cycle
Title: Expression of progesterone receptor membrane component (PGRMC) 1 and 2, serpine mRNA binding protein 1 (SERBP1) and nuclear progesterone receptor (PGR) in the bovine endometrium during the estrous cycle and the first trimester of pregnancy.

Data suggest that expression of PGRMC2 varies with region of oviduct (muscle; epithelium; stroma); this represents first evidence of PGRMC2 expression in bovine oviduct. Expression of PGRMC2 in bovine oviduct is both nuclear and cytoplasmic.
Title: Expression of nuclear progesterone receptor and progesterone receptor membrane components 1 and 2 in the oviduct of cyclic and pregnant cows during the post-ovulation period.

The following PGRMC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PGRMC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa41258	NM_001099060.1 Latest version!	Bos taurus progesterone receptor membrane component 2 (PGRMC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PGRMC2 ( NM_001099060.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001092530.1 Bos taurus progesterone receptor membrane component 2 (PGRMC2), mRNA.

Price & Availability↑

CloneID	OBa41258
Clone ID Related Accession (Same CDS sequence)	NM_001099060.1
Accession Version	NM_001099060.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 672bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-13
Organism	Bos taurus(cattle)
Product	membrane-associated progesterone receptor component 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC142203.1. On Jun 26, 2007 this sequence version replaced XM_613630.3. ##Evidence-Data-START## Transcript exon combination :: BC142203.1, EE364241.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCGG GTGATGGGGA CGTGAATTTA GGCACCCTGG GGAGTGGCAG CGAGAGCAGC 
AGCGACGGTA GTAGCGAGAG CCCGGGCGGC GCGGGAGCGG CAGCAGAAGG GGGCAGCTGC 
TTGGCAACGG CGTTGGCGCT TCTGACGGGG GGCGGGGAGA TGCTGCTGAA CGTGGCTCTG 
GTGGCGCTGG TGTTGCTGGG GGCCTACCGG CTGTGGGTGC GCTGGGGGCG GCGGGGTCTG 
GGCGCCGGGG CCGGAGCGGG CGAAGAGAGC CCCGCTGCCT CTTTGCCTCG TATGAAGAAG 
CGGGACTTCA GCTTGGAGCA GCTGCGCCAG TACGACGGGT CTCGCAACCC GCGCATCCTG 
CTTGCGGTCA ATGGGAAAGT CTTCGACGTG ACCAAAGGCA GCAAGTTCTA CGGCCCGGCG 
GGTCCATATG GAATATTTGC TGGTAGGGAT GCCTCCAGAG GACTGGCAAC ATTTTGCCTA 
GATAAAGATG CACTTAAAGA TGAATATGAT GATCTCTCAG ATTTGAATGC TGTACAAATG 
GAGAGTGTTC GAGAATGGGA AATGCAGTTT AAAGAAAAAT ATGATTATGT AGGCAGACTC 
CTAAAACCAG GGGAAGAACC GTCAGAATAT ACAGATGAAG AAGATACCAA GGATCACAAT 
AAACAGGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001092530.1
CDS	4..675
Translation	MAAGDGDVNLGTLGSGSESSSDGSSESPGGAGAAAEGGSCLATALALLTGGGEMLLNVALVALVLLGAYRLWVRWGRRGLGAGAGAGEESPAASLPRMKKRDFSLEQLRQYDGSRNPRILLAVNGKVFDVTKGSKFYGPAGPYGIFAGRDASRGLATFCLDKDALKDEYDDLSDLNAVQMESVREWEMQFKEKYDYVGRLLKPGEEPSEYTDEEDTKDHNKQD

Target ORF information:

RefSeq Version	NM_001099060.1
Organism	Bos taurus(cattle)
Definition	Bos taurus progesterone receptor membrane component 2 (PGRMC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001099060.1

ORF Insert Sequence:

ATGGCGGCGG GTGATGGGGA CGTGAATTTA GGCACCCTGG GGAGTGGCAG CGAGAGCAGC 
AGCGACGGTA GTAGCGAGAG CCCGGGCGGC GCGGGAGCGG CAGCAGAAGG GGGCAGCTGC 
TTGGCAACGG CGTTGGCGCT TCTGACGGGG GGCGGGGAGA TGCTGCTGAA CGTGGCTCTG 
GTGGCGCTGG TGTTGCTGGG GGCCTACCGG CTGTGGGTGC GCTGGGGGCG GCGGGGTCTG 
GGCGCCGGGG CCGGAGCGGG CGAAGAGAGC CCCGCTGCCT CTTTGCCTCG TATGAAGAAG 
CGGGACTTCA GCTTGGAGCA GCTGCGCCAG TACGACGGGT CTCGCAACCC GCGCATCCTG 
CTTGCGGTCA ATGGGAAAGT CTTCGACGTG ACCAAAGGCA GCAAGTTCTA CGGCCCGGCG 
GGTCCATATG GAATATTTGC TGGTAGGGAT GCCTCCAGAG GACTGGCAAC ATTTTGCCTA 
GATAAAGATG CACTTAAAGA TGAATATGAT GATCTCTCAG ATTTGAATGC TGTACAAATG 
GAGAGTGTTC GAGAATGGGA AATGCAGTTT AAAGAAAAAT ATGATTATGT AGGCAGACTC 
CTAAAACCAG GGGAAGAACC GTCAGAATAT ACAGATGAAG AAGATACCAA GGATCACAAT 
AAACAGGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression and localization of progesterone receptor membrane component 1 and 2 and serpine mRNA binding protein 1 in the bovine corpus luteum during the estrous cycle and the first trimester of pregnancy.
Theriogenology82(8)1086-93(2014 Nov)
Kowalik MK,Rekawiecki R,Kotwica J

Expression of progesterone receptor membrane component (PGRMC) 1 and 2, serpine mRNA binding protein 1 (SERBP1) and nuclear progesterone receptor (PGR) in the bovine endometrium during the estrous cycle and the first trimester of pregnancy.
Reproductive biology13(1)15-23(2013 Mar)
Kowalik MK,Slonina D,Rekawiecki R,Kotwica J

Expression of nuclear progesterone receptor and progesterone receptor membrane components 1 and 2 in the oviduct of cyclic and pregnant cows during the post-ovulation period.
Reproductive biology and endocrinology : RB&E1076(2012 Sep)
Saint-Dizier M,Sandra O,Ployart S,Chebrout M,Constant F

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Isolation and characterization of hepatic and intestinal expressed sequence tags potentially involved in trait differentiation between cows of different metabolic type.
Mammalian genome : official journal of the International Mammalian Genome Society12(7)528-37(2001 Jul)
Dorroch U,Goldammer T,Brunner RM,Kata SR,K?hn C,Womack JE,Schwerin M

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PGRMC2 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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