Gene Symbol | TUBA1A |
Entrez Gene ID | 404053 |
Full Name | tubulin, alpha 1a |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » TUBA1A cDNA ORF clone
Gene Symbol | TUBA1A |
Entrez Gene ID | 404053 |
Full Name | tubulin, alpha 1a |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_001166505.1 | NP_001159977.1 | tubulin alpha-1B chain |
XM_005206262.1 | XP_005206319.1 | tubulin alpha-1B chain isoform X1 |
XM_005206262.2 | XP_005206319.1 | tubulin alpha-1B chain isoform X1 |
Pan troglodytes (chimpanzee) | TUBA1A | NP_001092014.1 |
TUBA1A | XP_001108924.2 | |
Gallus gallus (chicken) | TUBA3E | XP_419249.3 |
Bos taurus (cattle) | TUBA1A | NP_001159977.1 |
Mus musculus (house mouse) | Tuba1a | NP_035783.1 |
Caenorhabditis elegans (roundworm) | tba-5 | NP_492268.1 |
Homo sapiens (human) | TUBA1A | NP_006000.2 |
Canis lupus familiaris (dog) | TUBA1A | XP_862471.2 |
Danio rerio (zebrafish) | tuba1l2 | NP_001177911.1 |
Rattus norvegicus (Norway rat) | Tuba1a | NP_071634.1 |
Xenopus tropicalis (tropical clawed frog) | tuba1b | XP_002935154.1 |
Tubulin acetylation protects long-lived microtubules against mechanical ageing.
Portran D, Schaedel L, Xu Z, Th?ry M, Nachury MV
Nature cell biology19(4)391-398(2017 Apr)
The structure of the complex between ?-tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism.
Serna M, Carranza G, Mart?n-Benito J, Janowski R, Canals A, Coll M, Zabala JC, Valpuesta JM
Journal of cell science128(9)1824-34(2015 May)
Effects of ?-tubulin K40 acetylation and detyrosination on kinesin-1 motility in a purified system.
Kaul N, Soppina V, Verhey KJ
Biophysical journal106(12)2636-43(2014 Jun)
ATP transport through VDAC and the VDAC-tubulin complex probed by equilibrium and nonequilibrium MD simulations.
Noskov SY, Rostovtseva TK, Bezrukov SM
Biochemistry52(51)9246-56(2013 Dec)
Structural basis of tubulin tyrosination by tubulin tyrosine ligase.
Prota AE, Magiera MM, Kuijpers M, Bargsten K, Frey D, Wieser M, Jaussi R, Hoogenraad CC, Kammerer RA, Janke C, Steinmetz MO
The Journal of cell biology200(3)259-70(2013 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Lys40 of alpha-tubulin acetylation directly weakens inter-protofilament interactions.
Title: Tubulin acetylation protects long-lived microtubules against mechanical ageing.
the role of the human TBCE and TBCB chaperones in alpha-tubulin-beta-tubulin dissociation, was investigated.
Title: The structure of the complex between ?-tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism.
Lysine 40 acetylation of alpha-tubulin does not result in significant changes in kinesin-1's landing rate or motility parameters.
Title: Effects of ?-tubulin K40 acetylation and detyrosination on kinesin-1 motility in a purified system.
Data suggest presence of unstructured C-terminal tubulin tail in Vdac1 pore (voltage-dependent anion channel 1) decreases pore's conductance and switches pore's selectivity from anionic to cationic rendering ATP transport virtually impossible.
Title: ATP transport through VDAC and the VDAC-tubulin complex probed by equilibrium and nonequilibrium MD simulations.
TTL has specifically evolved to recognize and modify tubulin.
Title: Structural basis of tubulin tyrosination by tubulin tyrosine ligase.
The following TUBA1A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TUBA1A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa01457 | |
Clone ID Related Accession (Same CDS sequence) | NM_001166505.1 | |
Accession Version | NM_001166505.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Bos taurus(cattle) | |
Product | tubulin alpha-1B chain | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH175948.1, EE335129.1 and EE346571.1. On Oct 28, 2009 this sequence version replaced XM_876383.3. ##Evidence-Data-START## Transcript exon combination :: EH175948.1, DV915714.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCGTGAGT GCATCTCCAT CCACGTTGGC CAGGCTGGTG TCCAGATCGG CAATGCCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001159977.1 |
CDS | 343..1698 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001166505.1 |
1 | ATGCGTGAGT GCATCTCCAT CCACGTTGGC CAGGCTGGTG TCCAGATCGG CAATGCCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa19184 | |
Clone ID Related Accession (Same CDS sequence) | XM_005206262.1 , XM_005206262.2 | |
Accession Version | XM_005206262.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1251bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | tubulin alpha-1B chain isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103920.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCAAGTG ACAAGACTAT TGGGGGAGGA GACGACTCCT TCAACACCTT CTTCAGTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005206319.1 |
CDS | 511..1761 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005206262.1 |
1 | ATGCCAAGTG ACAAGACTAT TGGGGGAGGA GACGACTCCT TCAACACCTT CTTCAGTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa19184 | |
Clone ID Related Accession (Same CDS sequence) | XM_005206262.1 , XM_005206262.2 | |
Accession Version | XM_005206262.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1251bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tubulin alpha-1B chain isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037332.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005206262.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCAAGTG ACAAGACTAT TGGGGGAGGA GACGACTCCT TCAACACCTT CTTCAGTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005206319.1 |
CDS | 521..1771 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005206262.2 |
1 | ATGCCAAGTG ACAAGACTAT TGGGGGAGGA GACGACTCCT TCAACACCTT CTTCAGTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Tubulin acetylation protects long-lived microtubules against mechanical ageing. |
The structure of the complex between ?-tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism. |
Effects of ?-tubulin K40 acetylation and detyrosination on kinesin-1 motility in a purified system. |
ATP transport through VDAC and the VDAC-tubulin complex probed by equilibrium and nonequilibrium MD simulations. |
Structural basis of tubulin tyrosination by tubulin tyrosine ligase. |