Gene Symbol | ITGB3 |
Entrez Gene ID | 282642 |
Full Name | integrin subunit beta 3 |
Synonyms | INTB3 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » ITGB3 cDNA ORF clone
Gene Symbol | ITGB3 |
Entrez Gene ID | 282642 |
Full Name | integrin subunit beta 3 |
Synonyms | INTB3 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_015458860.1 | XP_015314346.1 | integrin beta-3 isoform X1 |
NM_001206490.3 | NP_001193419.1 | integrin beta-3 precursor |
XM_024979642.1 | XP_024835410.1 | integrin beta-3 isoform X2 |
XM_024979641.1 | XP_024835409.1 | integrin beta-3 isoform X1 |
NM_001206490.2 | NP_001193419.1 | integrin beta-3 precursor |
Pan troglodytes (chimpanzee) | ITGB3 | XP_523684.2 |
Mus musculus (house mouse) | Itgb3 | NP_058060.2 |
Homo sapiens (human) | ITGB3 | NP_000203.2 |
ITGB3 | XP_001116013.1 | |
Bos taurus (cattle) | ITGB3 | NP_001193419.1 |
Xenopus tropicalis (tropical clawed frog) | itgb3 | XP_002942401.2 |
Canis lupus familiaris (dog) | ITGB3 | NP_001003162.1 |
Rattus norvegicus (Norway rat) | Itgb3 | NP_714942.1 |
Gallus gallus (chicken) | ITGB3 | NP_989646.1 |
Danio rerio (zebrafish) | itgb3b | NP_001076417.1 |
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Specific integrin subunits in bovine oocytes, including novel sequences for alpha 6 and beta 3 subunits.
Pate BJ, White KL, Winger QA, Rickords LF, Aston KI, Sessons BR, Li GP, Campbell KD, Weimer B, Bunch TD
Molecular reproduction and development74(5)600-7(2007 May)
Matrix-specific suppression of integrin activation in shear stress signaling.
Orr AW, Ginsberg MH, Shattil SJ, Deckmyn H, Schwartz MA
Molecular biology of the cell17(11)4686-97(2006 Nov)
Interactions of foot-and-mouth disease virus with soluble bovine alphaVbeta3 and alphaVbeta6 integrins.
Duque H, LaRocco M, Golde WT, Baxt B
Journal of virology78(18)9773-81(2004 Sep)
Regulation of Ca2+-dependent K+ current by alphavbeta3 integrin engagement in vascular endothelium.
Kawasaki J, Davis GE, Davis MJ
The Journal of biological chemistry279(13)12959-66(2004 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The presence of these integrin subunits on the bovine oocyte vitelline membrane supports the hypothesis that sperm-oocyte interactions in the bovine are mediated by integrins.
Title: Specific integrin subunits in bovine oocytes, including novel sequences for alpha 6 and beta 3 subunits.
Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
Title: Matrix-specific suppression of integrin activation in shear stress signaling.
identified as receptor for foot-and-mouth disease virus
Title: Interactions of foot-and-mouth disease virus with soluble bovine alphaVbeta3 and alphaVbeta6 integrins.
alphavbeta3 integrin engagement in vascular endothelium regulates Ca2+-dependent K+ current
Title: Regulation of Ca2+-dependent K+ current by alphavbeta3 integrin engagement in vascular endothelium.
The following ITGB3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITGB3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa39613 | |
Clone ID Related Accession (Same CDS sequence) | NM_001206490.3 , NM_001206490.2 | |
Accession Version | NM_001206490.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2355bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-15 | |
Organism | Bos taurus(cattle) | |
Product | integrin beta-3 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from NKLS02000019.1. On Jun 16, 2018 this sequence version replaced NM_001206490.2. Sequence Note: This RefSeq record was created from genomic sequence data. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR5571259.35479.1, SRR5571260.47326.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145415 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCGAGCGC GGCGGCTCTG GGCAGCGGTG CTGGTGGTGG GGGCGCTGGC GGGCGTCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001193419.1 |
CDS | 7..2361 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001206490.3 |
1 | ATGCGAGCGC GGCGGCTCTG GGCAGCGGTG CTGGTGGTGG GGGCGCTGGC GGGCGTCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa39613 | |
Clone ID Related Accession (Same CDS sequence) | NM_001206490.3 , NM_001206490.2 | |
Accession Version | NM_001206490.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2355bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-22 | |
Organism | Bos taurus(cattle) | |
Product | integrin beta-3 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DAAA02049290.1. On Feb 23, 2016 this sequence version replaced NM_001206490.1. Sequence Note: This RefSeq record was created from genomic sequence data. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: JX475452.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02822088, SAMN02822090 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCGAGCGC GGCGGCTCTG GGCAGCGGTG CTGGTGGTGG GGGCGCTGGC GGGCGTCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001193419.1 |
CDS | 7..2361 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001206490.2 |
1 | ATGCGAGCGC GGCGGCTCTG GGCAGCGGTG CTGGTGGTGG GGGCGCTGGC GGGCGTCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa226010 | |
Clone ID Related Accession (Same CDS sequence) | XM_024979641.1 | |
Accession Version | XM_024979641.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2304bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | integrin beta-3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037346.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAAAGTA TTTCAGGGCC CAACATCTGT GCCACACGAG GTGTGAGCTC CTGCCAGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024835409.1 |
CDS | 16..2319 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024979641.1 |
1 | ATGCAAAGTA TTTCAGGGCC CAACATCTGT GCCACACGAG GTGTGAGCTC CTGCCAGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa226011 | |
Clone ID Related Accession (Same CDS sequence) | XM_024979642.1 | |
Accession Version | XM_024979642.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2334bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | integrin beta-3 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037346.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACTGTA GCCCGTCAGG CTCCTCTGGT CTGTGGAATT CTCCAGGGCC CAACATCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024835410.1 |
CDS | 16..2349 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024979642.1 |
1 | ATGGACTGTA GCCCGTCAGG CTCCTCTGGT CTGTGGAATT CTCCAGGGCC CAACATCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa93966 | |
Clone ID Related Accession (Same CDS sequence) | XM_015458860.1 | |
Accession Version | XM_015458860.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1938bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | integrin beta-3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104497.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACTTGT CTTACTCCAT GAAGGATGAC CTGCGGAACA TCCAGAACCT GGGTACCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015314346.1 |
CDS | 481..2418 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015458860.1 |
1 | ATGGACTTGT CTTACTCCAT GAAGGATGAC CTGCGGAACA TCCAGAACCT GGGTACCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A whole-genome assembly of the domestic cow, Bos taurus. |
Specific integrin subunits in bovine oocytes, including novel sequences for alpha 6 and beta 3 subunits. |
Matrix-specific suppression of integrin activation in shear stress signaling. |
Interactions of foot-and-mouth disease virus with soluble bovine alphaVbeta3 and alphaVbeta6 integrins. |
Regulation of Ca2+-dependent K+ current by alphavbeta3 integrin engagement in vascular endothelium. |