Gene Symbol | ITGB3 |
Entrez Gene ID | 3690 |
Full Name | integrin subunit beta 3 |
Synonyms | BDPLT16,BDPLT2,CD61,GP3A,GPIIIa,GT |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Glanzmann thrombasthenia, 273800 (3); Thrombocytopenia, neonatal alloimmune (3); {Myocardial infarction, susceptibility to}, 608446 (3); Purpura, posttransfusion (3); Bleeding disorder, platelet-type, 16, autosomal dominant, 187800 (3) |