itgb3b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	itgb3b
Entrez Gene ID	100001836
Full Name	integrin beta 3b
Synonyms	itgb3.1
General protein information	Preferred Names integrin beta 3b Names integrin beta-3 integrin beta 3.1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001082948.1	NP_001076417.1	integrin beta-3 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ITGB3	XP_523684.2
Mus musculus (house mouse)	Itgb3	NP_058060.2
Homo sapiens (human)	ITGB3	NP_000203.2
	ITGB3	XP_001116013.1
Bos taurus (cattle)	ITGB3	NP_001193419.1
Xenopus tropicalis (tropical clawed frog)	itgb3	XP_002942401.2
Canis lupus familiaris (dog)	ITGB3	NP_001003162.1
Rattus norvegicus (Norway rat)	Itgb3	NP_714942.1
Gallus gallus (chicken)	ITGB3	NP_989646.1
Danio rerio (zebrafish)	itgb3b	NP_001076417.1

Gene Ontology
Bibliography

Related articles in PubMed

Toxicity and anti-angiogenicity evaluation of Pak1 inhibitor IPA-3 using zebrafish embryo model.
Jagadeeshan S, Sagayaraj RV, Paneerselvan N, Ghouse SS, Malathi R
Cell biology and toxicology33(1)41-56(2017 Feb)

Biting into the Genome to Phenome Map: Developmental Genetic Modularity of Cichlid Fish Dentitions.
Hulsey CD, Fraser GJ, Meyer A
Integrative and comparative biology56(3)373-88(2016 Sep)

Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells.
Macaulay IC, Svensson V, Labalette C, Ferreira L, Hamey F, Voet T, Teichmann SA, Cvejic A
Cell reports14(4)966-977(2016 Feb)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

beta3.1 is the major beta3 paralog that associates with alphaV in zebrafish;pharyngeal dentitions appear to represent a unique expression field for alphaV and beta3.
Title: The zebrafish vitronectin receptor: characterization of integrin alphaV and beta3 expression patterns in early vertebrate development.

The following itgb3b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the itgb3b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01324	NM_001082948.1 Latest version!	Danio rerio integrin beta 3b (itgb3b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

itgb3b ( NM_001082948.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001076417.1 Danio rerio integrin beta 3b (itgb3b), mRNA.

Price & Availability↑

CloneID	ODa01324
Clone ID Related Accession (Same CDS sequence)	NM_001082948.1
Accession Version	NM_001082948.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2373bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-05
Organism	Danio rerio(zebrafish)
Product	integrin beta-3 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ178646.1. On Mar 15, 2007 this sequence version replaced XM_001337850.1. ##Evidence-Data-START## Transcript exon combination :: DQ178646.1, BC163207.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN02259097 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGAAA CTTCAGCCAA ACTCTTCAGC TTATGGGTTT ACTGTGTAAT TATTTTCCTA 
GCTGATGTTG GACTAGGTTC TAACGTCTGT ACTTCTCGAG GAGCCAGTAC ATGTCAGCAG 
TGCCTGGCTG TGCATCCAAC CTGTGCCTGG TGCTTTCAAG AGGATTTTGG ACAAGATGTT 
CCTGGCTCTT CCCGATGTGA CCTGAAAAGG AACCTTGTAG AAGCAGGATG CAACAAGGGA 
GCTCTGGAGT ATCCAACCAG CAAAATGCAC GTAAAAGAGA ATGAAGATCT CAGTGACAAG 
GCCTCAGGAT CCACCACTGA CGTCACCCAG ATCCAACCTC AAAGCATACA CATCTCTCTG 
AGACCCGATG ATTCGCAGGT TTTCAAGCTG AAAGTCCGAC AGGTAGAGGA CTACCCTGTG 
GATTTGTACT ATCTGATGGA CCTGTCCTAC TCCATGAATG ACGACTTGTC TCAGTTGAGA 
CGGCTGGGGC GAGGCCTGGC TGAAGAGATG AGCAAAACCA CTAGTAATCT GCGCATGGGC 
TTTGGGGCTT TTGTGGATAA ACCTGTGTCC CCGTACATGT ACATCTCCCC TGAGGAAGCC 
GTGTTAAATC CCTGCTACTC AATCCCGTAC AAATGCCAGC CTCAGTTTGG CTACAGACAC 
GTTCTGTCTC TGACGGAGGA GGTGAACCGC TTTACAGAAG AAGTGAAGAA ACAGAAGGTG 
TCCCGAAACA GGGACGCGCC AGAGGGAGGC TTTGACGCCA TCATACAAGC AGCCGTGTGC 
AAGGACAAAA TTGGTTGGAG ACCAGGTGCA TCCCACTTGC TGGTTTTCAC TACAGATGCC 
AAAACACATG TGGCACTGGA TGGGCGTATG GCAGGAATTG TGCGACCCAA TGATGGCCAA 
TGCTATGTGG GCAGGGACAA CATCTACAAT ATGTCCACAA CTATGGACTA CCCATCCCTG 
GCACTAATCA CAGAGAAAAT GTCTGAGAAC AATATAAATC TGATCTTTGC TGTAACTAGC 
CATGTGGAAT CACTCTATAA GAACTACAGT GAGTTGATCC CTGGCACTGC AGTGGGTACG 
CTGTCCGAGG ACTCTCATAA CGTCATCCAG CTGATCCAGG ATGCGTATGC TAAACTGCGC 
TCTAAGGTAG AGCTGGAGCT CTTGAACGTC CCGGAAGAGC TCAGTCTAAC ATTTAATGCC 
ACATGTCTCA ACGGAGAGGT CATTCCTGGG CTGAGATCCT GCTCAGGCCT CAAAAGAGGA 
GATACCGTGT CCTTCAGTGT TGAAGCCCGA GCCAGAGGCT GTCCGAAGGA GAAGCGCAAA 
ACCTTCACTA TAAAACCAGT GGGCTTCAAA GACACCTTGC AGATCACAGT CAACTTTGAA 
TGTGAGTGTA AATGCCAAGC AAAGGCTGAG CCTGAGAGTC CCGTCTGCCA CCACGGCAAT 
GGCACCTATG AGTGTGGCAT CTGCCTGTGT CACCCGGGGC GGCTGGGTCC CCGCTGCGAA 
TGTGCAGAGG GCGACTACAG CCCAACAGAA CAGGACGCCT GCAGTGGGCC AGACAAGGTG 
ATCTGCAGCG GCCGGGGAGA CTGTGTGTGC GGACAGTGCG TCTGTCACAA TAATGACTTC 
GGCAAAGTAT GGGGGAAGAG ATGCGAGTGT GATGATTTCA GCTGCCTGCG CTATAAAGGA 
GAGCTCTGCT CAGGTCATGG CACTTGTTAC TGTGGGTTTT GTCAGTGTGA TCCGGACTGG 
AAAGGGGAAA ACTGCAACTG TTCCACTCGA ACAGACACCT GTATGTCCAG CTTGGGTCTG 
CTGTGCAGCG GTCGGGGTCA GTGTGTGTGT GGCAGCTGTG AATGTACTCA ACCAGGTGCT 
TATGGATCTA CCTGCGACAA ATGTCCCACC TGCCCTGACG CCTGCACACT GAAGAAGGAG 
TGTGTAGAGT GTAAGCACTT CAAGAGAGGG AAACTCTTCG ATGATGATTC CTGCACTCGC 
ATCTGCAGAG ATGAAATCAG ACTAGTGGAT GATCTGGTGT TCCATGATAA GAATGCAGTG 
AATTGCACCT ATAAGGATGA GGACGACTGT GTGCAAAGGT TTCAGTACTA CGAGGACAAC 
AGTGGCAAAT CCATCTTGTC TCTGGTCAAA GAGCCAGATT GCCCTAAAGG CCCCGATATC 
TTGGTGGTGC TGCTGTCAGT AGCTGGTGCC ATCTTATTCT TGGGTCTTGC CGCCTTGCTT 
ATCTGGAAAC TATTAATAAC CATTCATGAT CGGCGTGAAT TTGCGAAGTT TGAGGAGGAG 
CGGGCACGAG CTAAGTGGGA AACGGGTCAC AATCCGCTTT ATAAAGGCGC CACGTCGACA 
TTCACAAACA TCACATATCG AGGCAAAGAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001076417.1
CDS	78..2450
Translation	MEETSAKLFSLWVYCVIIFLADVGLGSNVCTSRGASTCQQCLAVHPTCAWCFQEDFGQDVPGSSRCDLKRNLVEAGCNKGALEYPTSKMHVKENEDLSDKASGSTTDVTQIQPQSIHISLRPDDSQVFKLKVRQVEDYPVDLYYLMDLSYSMNDDLSQLRRLGRGLAEEMSKTTSNLRMGFGAFVDKPVSPYMYISPEEAVLNPCYSIPYKCQPQFGYRHVLSLTEEVNRFTEEVKKQKVSRNRDAPEGGFDAIIQAAVCKDKIGWRPGASHLLVFTTDAKTHVALDGRMAGIVRPNDGQCYVGRDNIYNMSTTMDYPSLALITEKMSENNINLIFAVTSHVESLYKNYSELIPGTAVGTLSEDSHNVIQLIQDAYAKLRSKVELELLNVPEELSLTFNATCLNGEVIPGLRSCSGLKRGDTVSFSVEARARGCPKEKRKTFTIKPVGFKDTLQITVNFECECKCQAKAEPESPVCHHGNGTYECGICLCHPGRLGPRCECAEGDYSPTEQDACSGPDKVICSGRGDCVCGQCVCHNNDFGKVWGKRCECDDFSCLRYKGELCSGHGTCYCGFCQCDPDWKGENCNCSTRTDTCMSSLGLLCSGRGQCVCGSCECTQPGAYGSTCDKCPTCPDACTLKKECVECKHFKRGKLFDDDSCTRICRDEIRLVDDLVFHDKNAVNCTYKDEDDCVQRFQYYEDNSGKSILSLVKEPDCPKGPDILVVLLSVAGAILFLGLAALLIWKLLITIHDRREFAKFEEERARAKWETGHNPLYKGATSTFTNITYRGKD

Target ORF information:

RefSeq Version	NM_001082948.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio integrin beta 3b (itgb3b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001082948.1

ORF Insert Sequence:

ATGGAGGAAA CTTCAGCCAA ACTCTTCAGC TTATGGGTTT ACTGTGTAAT TATTTTCCTA 
GCTGATGTTG GACTAGGTTC TAACGTCTGT ACTTCTCGAG GAGCCAGTAC ATGTCAGCAG 
TGCCTGGCTG TGCATCCAAC CTGTGCCTGG TGCTTTCAAG AGGATTTTGG ACAAGATGTT 
CCTGGCTCTT CCCGATGTGA CCTGAAAAGG AACCTTGTAG AAGCAGGATG CAACAAGGGA 
GCTCTGGAGT ATCCAACCAG CAAAATGCAC GTAAAAGAGA ATGAAGATCT CAGTGACAAG 
GCCTCAGGAT CCACCACTGA CGTCACCCAG ATCCAACCTC AAAGCATACA CATCTCTCTG 
AGACCCGATG ATTCGCAGGT TTTCAAGCTG AAAGTCCGAC AGGTAGAGGA CTACCCTGTG 
GATTTGTACT ATCTGATGGA CCTGTCCTAC TCCATGAATG ACGACTTGTC TCAGTTGAGA 
CGGCTGGGGC GAGGCCTGGC TGAAGAGATG AGCAAAACCA CTAGTAATCT GCGCATGGGC 
TTTGGGGCTT TTGTGGATAA ACCTGTGTCC CCGTACATGT ACATCTCCCC TGAGGAAGCC 
GTGTTAAATC CCTGCTACTC AATCCCGTAC AAATGCCAGC CTCAGTTTGG CTACAGACAC 
GTTCTGTCTC TGACGGAGGA GGTGAACCGC TTTACAGAAG AAGTGAAGAA ACAGAAGGTG 
TCCCGAAACA GGGACGCGCC AGAGGGAGGC TTTGACGCCA TCATACAAGC AGCCGTGTGC 
AAGGACAAAA TTGGTTGGAG ACCAGGTGCA TCCCACTTGC TGGTTTTCAC TACAGATGCC 
AAAACACATG TGGCACTGGA TGGGCGTATG GCAGGAATTG TGCGACCCAA TGATGGCCAA 
TGCTATGTGG GCAGGGACAA CATCTACAAT ATGTCCACAA CTATGGACTA CCCATCCCTG 
GCACTAATCA CAGAGAAAAT GTCTGAGAAC AATATAAATC TGATCTTTGC TGTAACTAGC 
CATGTGGAAT CACTCTATAA GAACTACAGT GAGTTGATCC CTGGCACTGC AGTGGGTACG 
CTGTCCGAGG ACTCTCATAA CGTCATCCAG CTGATCCAGG ATGCGTATGC TAAACTGCGC 
TCTAAGGTAG AGCTGGAGCT CTTGAACGTC CCGGAAGAGC TCAGTCTAAC ATTTAATGCC 
ACATGTCTCA ACGGAGAGGT CATTCCTGGG CTGAGATCCT GCTCAGGCCT CAAAAGAGGA 
GATACCGTGT CCTTCAGTGT TGAAGCCCGA GCCAGAGGCT GTCCGAAGGA GAAGCGCAAA 
ACCTTCACTA TAAAACCAGT GGGCTTCAAA GACACCTTGC AGATCACAGT CAACTTTGAA 
TGTGAGTGTA AATGCCAAGC AAAGGCTGAG CCTGAGAGTC CCGTCTGCCA CCACGGCAAT 
GGCACCTATG AGTGTGGCAT CTGCCTGTGT CACCCGGGGC GGCTGGGTCC CCGCTGCGAA 
TGTGCAGAGG GCGACTACAG CCCAACAGAA CAGGACGCCT GCAGTGGGCC AGACAAGGTG 
ATCTGCAGCG GCCGGGGAGA CTGTGTGTGC GGACAGTGCG TCTGTCACAA TAATGACTTC 
GGCAAAGTAT GGGGGAAGAG ATGCGAGTGT GATGATTTCA GCTGCCTGCG CTATAAAGGA 
GAGCTCTGCT CAGGTCATGG CACTTGTTAC TGTGGGTTTT GTCAGTGTGA TCCGGACTGG 
AAAGGGGAAA ACTGCAACTG TTCCACTCGA ACAGACACCT GTATGTCCAG CTTGGGTCTG 
CTGTGCAGCG GTCGGGGTCA GTGTGTGTGT GGCAGCTGTG AATGTACTCA ACCAGGTGCT 
TATGGATCTA CCTGCGACAA ATGTCCCACC TGCCCTGACG CCTGCACACT GAAGAAGGAG 
TGTGTAGAGT GTAAGCACTT CAAGAGAGGG AAACTCTTCG ATGATGATTC CTGCACTCGC 
ATCTGCAGAG ATGAAATCAG ACTAGTGGAT GATCTGGTGT TCCATGATAA GAATGCAGTG 
AATTGCACCT ATAAGGATGA GGACGACTGT GTGCAAAGGT TTCAGTACTA CGAGGACAAC 
AGTGGCAAAT CCATCTTGTC TCTGGTCAAA GAGCCAGATT GCCCTAAAGG CCCCGATATC 
TTGGTGGTGC TGCTGTCAGT AGCTGGTGCC ATCTTATTCT TGGGTCTTGC CGCCTTGCTT 
ATCTGGAAAC TATTAATAAC CATTCATGAT CGGCGTGAAT TTGCGAAGTT TGAGGAGGAG 
CGGGCACGAG CTAAGTGGGA AACGGGTCAC AATCCGCTTT ATAAAGGCGC CACGTCGACA 
TTCACAAACA TCACATATCG AGGCAAAGAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Toxicity and anti-angiogenicity evaluation of Pak1 inhibitor IPA-3 using zebrafish embryo model.
Cell biology and toxicology33(1)41-56(2017 Feb)
Jagadeeshan S,Sagayaraj RV,Paneerselvan N,Ghouse SS,Malathi R

Biting into the Genome to Phenome Map: Developmental Genetic Modularity of Cichlid Fish Dentitions.
Integrative and comparative biology56(3)373-88(2016 Sep)
Hulsey CD,Fraser GJ,Meyer A

Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells.
Cell reports14(4)966-977(2016 Feb)
Macaulay IC,Svensson V,Labalette C,Ferreira L,Hamey F,Voet T,Teichmann SA,Cvejic A

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

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itgb3b cDNA ORF clone, Danio rerio(zebrafish)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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