Gene Symbol | INSL3 |
Entrez Gene ID | 281870 |
Full Name | insulin like 3 |
Synonyms | RLF |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » INSL3 cDNA ORF clone
Gene Symbol | INSL3 |
Entrez Gene ID | 281870 |
Full Name | insulin like 3 |
Synonyms | RLF |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_174365.2 | NP_776790.1 | insulin-like 3 precursor |
Plasma insulin-like peptide 3 concentrations are acutely regulated by luteinizing hormone in pubertal Japanese?Black beef bulls.
Hannan MA, Fukami Y, Kawate N, Sakase M, Fukushima M, Pathirana IN, B?llesbach EE, Inaba T, Tamada H
Theriogenology84(9)1530-5(2015 Dec)
Ovarian expression of insulin-like peptide 3 (INSL3) and its receptor (RXFP2) during development of bovine antral follicles and corpora lutea and measurement of circulating INSL3 levels during synchronized estrous cycles.
Satchell L, Glister C, Bleach EC, Glencross RG, Bicknell AB, Dai Y, Anand-Ivell R, Ivell R, Knight PG
Endocrinology154(5)1897-906(2013 May)
Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production.
Glister C, Satchell L, Bathgate RA, Wade JD, Dai Y, Ivell R, Anand-Ivell R, Rodgers RJ, Knight PG
Proceedings of the National Academy of Sciences of the United States of America110(15)E1426-35(2013 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results suggested an acute regulation of INSL3 by luteinizing hormone (LH) because INSL3 concentrations increased immediately after endogenous and exogenous LH stimulation.
Title: Plasma insulin-like peptide 3 concentrations are acutely regulated by luteinizing hormone in pubertal Japanese?Black beef bulls.
The likely role of INSL3 as an important intrafollicular modulator of thecal interna cell function/steroidogenesis.
Title: Ovarian expression of insulin-like peptide 3 (INSL3) and its receptor (RXFP2) during development of bovine antral follicles and corpora lutea and measurement of circulating INSL3 levels during synchronized estrous cycles.
BMP6 has a role in downregulating INSL3 and CYP17A1 and other proteins that modulate ovarian androgen production
Title: Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production.
INSL3 plays a luteotropic role as a local regulator in the bovine corpus luteum.
Title: Possible role of insulin-like factor 3 in the bovine corpus luteum.
INSL3 provides the first example of a gender-specific fetal hormone with the potential to influence both placental and maternal physiology
Title: INSL3 in the ruminant: a powerful indicator of gender- and genetic-specific feto-maternal dialogue.
The following INSL3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the INSL3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa41241 | |
Clone ID Related Accession (Same CDS sequence) | NM_174365.2 | |
Accession Version | NM_174365.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 399bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Bos taurus(cattle) | |
Product | insulin-like 3 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF094580.1. On Jun 3, 2003 this sequence version replaced NM_174365.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF094580.1, DT860268.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145419, SAMN03145429 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGACCGTC GTCCGCTCAC CTGGGCTCTG GTGCTGCTGG GCCCGGCCCT TGCAATCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776790.1 |
CDS | 33..431 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174365.2 |
1 | ATGGACCGTC GTCCGCTCAC CTGGGCTCTG GTGCTGCTGG GCCCGGCCCT TGCAATCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Plasma insulin-like peptide 3 concentrations are acutely regulated by luteinizing hormone in pubertal Japanese?Black beef bulls. |
Ovarian expression of insulin-like peptide 3 (INSL3) and its receptor (RXFP2) during development of bovine antral follicles and corpora lutea and measurement of circulating INSL3 levels during synchronized estrous cycles. |
Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production. |