SCIN cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	SCIN
Entrez Gene ID	281478
Full Name	scinderin
General protein information	Preferred Names scinderin Names adseverin SC
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174177.2	NP_776602.1	adseverin

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Scin	NP_942043.1
Xenopus tropicalis (tropical clawed frog)	LOC100495760	XP_002939059.1
Homo sapiens (human)	SCIN	NP_001106177.1
Bos taurus (cattle)	SCIN	NP_776602.1
Pan troglodytes (chimpanzee)	SCIN	XP_527671.1
Canis lupus familiaris (dog)	SCIN	XP_005628852.1
Mus musculus (house mouse)	Scin	NP_001139668.1
	SCIN	XP_001082780.1
Gallus gallus (chicken)	SCIN	NP_001231522.1
Danio rerio (zebrafish)	scin	NP_001038583.1

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Expression of various scinderin domains in chromaffin cells indicates that this protein acts as a molecular switch in the control of actin filament dynamics and exocytosis.
Dumitrescu Pene T, Ros? SD, Lejen T, Marcu MG, Trifar? JM
Journal of neurochemistry92(4)780-9(2005 Feb)

Recombinant scinderin enhances exocytosis, an effect blocked by two scinderin-derived actin-binding peptides and PIP2.
Zhang L, Marcu MG, Nau-Staudt K, Trifar? JM
Neuron17(2)287-96(1996 Aug)

Molecular cloning and functional expression of chromaffin cell scinderin indicates that it belongs to the family of Ca(2+)-dependent F-actin severing proteins.
Marcu MG, Rodr?guez del Castillo A, Vitale ML, Trifar? JM
Molecular and cellular biochemistry141(2)153-65(1994 Dec)

Differential expression of bovine adseverin in adrenal gland revealed by in situ hybridization. Cloning of a cDNA for adseverin.
Nakamura S, Sakurai T, Nonomura Y
The Journal of biological chemistry269(8)5890-6(1994 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SCIN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SCIN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa41474	NM_174177.2 Latest version!	Bos taurus scinderin (SCIN), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SCIN ( NM_174177.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776602.1 Bos taurus scinderin (SCIN), mRNA.

Price & Availability↑

CloneID	OBa41474
Clone ID Related Accession (Same CDS sequence)	NM_174177.2
Accession Version	NM_174177.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2148bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-21
Organism	Bos taurus(cattle)
Product	adseverin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X78479.1. On or before Mar 29, 2005 this sequence version replaced XM_593214.1, NM_174177.1. ##Evidence-Data-START## Transcript exon combination :: X78479.1, BC133524.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END##

ATGGCCCAGG GGCTGTACCA CGAGGAGTTC GCCCGCGCGG GCAAGCGGGC GGGGCTGCAG 
GTCTGGAGAA TTGAGAAGCT GGAGCTGGTG CCGGTGCCCG AGAGCGCGTA TGGCAACTTC 
TACGTCGGGG ATGCCTACCT GGTGCTCCAC ACGACGCAGG CCAGCCGGGG CTTCACCTAC 
CGCCTGCACT TCTGGCTGGG AAAGGAGTGT ACTCAGGATG AAAGCACAGC AGCTGCCATC 
TTTACTGTTC AGATGGATGA CTATTTGGGT GGCAAACCTG TGCAGAACAG AGAACTTCAA 
GGCTATGAGT CTACGGATTT TGTTGGCTAC TTTAAAGGAG GTCTGAAATA CAAGGCTGGC 
GGTGTGGCGT CTGGACTCAA TCATGTGCTT ACAAATGACT TGACTGCTCA GAGGCTCCTG 
CATGTGAAAG GTCGGAGAGT CGTCAGGGCC ACGGAAGTTC CCCTAAGCTG GGACAGTTTC 
AACAAGGGTG ACTGCTTCAT CATTGACCTT GGCACTGAAA TTTACCAGTG GTGTGGATCT 
TCTTGCAACA AGTACGAGCG CCTGAAGGCC AGCCAGGTTG CCATCGGCAT TCGGGACAAT 
GAAAGGAAAG GCAGAGCTCA GCTGATTGTG GTAGAAGAAG GGAGTGAACC ATCAGAGCTT 
ACAAAGGTAT TAGGGGAAAA GCCAAAGCTT ACCCATGGAG AAGATGATGA TGACATCAAA 
GCAGATATAA CTAATAGGAA AATGGCTAAA CTCTACATGG TTTCAGATGC CAGTGGCTCC 
ATGAAAGTGA GTCTGGTGGC AGAAGAAAAC CCCTTCTCCA TGGCGATGCT TCTGTCTGAA 
GAATGCTTCA TTTTGGACCA CGGTGCTGCA AAACAGATTT TTGTATGGAA AGGTAAAGAT 
GCTAATCCCC AGGAGAGAAA GGCTGCCATG AAGACAGCTG AGGAATTCCT ACAGCAAATG 
AATTATTCTA CGAATACCCA AATTCAACTT CTTCCAGAAG GAGGTGAAAC ACCAATCTTC 
AAACAGTTCT TTAAGGACTG GAGAGATAGA GATCAGAGCG ATGGCTTCGG GAAAGTGTAT 
GTCACAGAAA AAGTGGCTCA CGTAAAACAA ATTCCATTTG ATGCCTCAAA ATTGCACAGC 
TCCCCACAAA TGGCAGCCCA GCATCACGTG GTGGATGACG GTTCTGGCAA AGTGCAGATT 
TGGCGTGTAG AAAACAACGG TAGGGTCGAA ATTGACCGAA ACTCGTATGG TGAATTCTAT 
GGTGGTGATT GCTACATTAT ACTTTACACT TATCCCAGAG GACAGATTAT CTACACCTGG 
CAAGGAGCAA ATGCCACACG GGATGAGCTG ACAACCTCCG ATTCCCGACT GTTCAGTTGG 
ATAGATCCCT CGGGGGATCA GGCTGTGCAG ATTCGAGTCT CCCAAGGCAA AGAACCTGCT 
CACCTGCTGA GTTTGTTCAA AGACAAACCG CTCATTATTT ACAAGAACGG AACATCAAAG 
AAAGAAGGTC AGGCACCAGC CCCCCCTATA CGCCTCTTTC AAGTCCGAAG AAACCTGGAT 
TCGTACACCA GAATTATGGA GGTAGATGTT GATGCAAACT CATTGAATTC CAATGATGTT 
TTTGTCCTGA AACTGCGACA AAATAATGGC TACATCTGGA TAGGAAAAGG CTCCACACAG 
GAGGAGGAGA AAGGAGCAGA GTACGTGGCA AGCGTCCTCA AATGCAAAAC TTCGACGATT 
CAGGAAGGCA AGGAACCAGA GGAGTTTTGG AATTCCCTTG GAGGGAAAAA AGACTACCAG 
ACCTCTCCTC TGCTAGAATC CCAGGCTGAA GACCATCCAC CTCGGCTTTA CGGCTGCTCC 
AACAAAACTG GAAGATTCAT TATTGAAGAG GTTCCAGGAG AGTTCACCCA GGATGATTTA 
GCAGAAGATG ATGTCATGCT GTTAGATGCT TGGGAACAGA TTTTTATTTG GATTGGAAAA 
GATGCCAATG AAGTTGAGAA ATCAGAATCT CTGAAGTCTG CCAAAATATA CCTTGAGACC 
GACCCTTCTG GAAGAGACAA GAGGACGCCA ATTGTCATCA TAAAACAGGG TCATGAGCCA 
CCTACTTTCA CAGGCTGGTT CCTGGGCTGG GATTCCAGCA GGTGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776602.1
CDS	78..2225
Translation	MAQGLYHEEFARAGKRAGLQVWRIEKLELVPVPESAYGNFYVGDAYLVLHTTQASRGFTYRLHFWLGKECTQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESTDFVGYFKGGLKYKAGGVASGLNHVLTNDLTAQRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKASQVAIGIRDNERKGRAQLIVVEEGSEPSELTKVLGEKPKLTHGEDDDDIKADITNRKMAKLYMVSDASGSMKVSLVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSTNTQIQLLPEGGETPIFKQFFKDWRDRDQSDGFGKVYVTEKVAHVKQIPFDASKLHSSPQMAAQHHVVDDGSGKVQIWRVENNGRVEIDRNSYGEFYGGDCYIILYTYPRGQIIYTWQGANATRDELTTSDSRLFSWIDPSGDQAVQIRVSQGKEPAHLLSLFKDKPLIIYKNGTSKKEGQAPAPPIRLFQVRRNLDSYTRIMEVDVDANSLNSNDVFVLKLRQNNGYIWIGKGSTQEEEKGAEYVASVLKCKTSTIQEGKEPEEFWNSLGGKKDYQTSPLLESQAEDHPPRLYGCSNKTGRFIIEEVPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKSESLKSAKIYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSRW

Target ORF information:

RefSeq Version	NM_174177.2
Organism	Bos taurus(cattle)
Definition	Bos taurus scinderin (SCIN), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174177.2

ORF Insert Sequence:

ATGGCCCAGG GGCTGTACCA CGAGGAGTTC GCCCGCGCGG GCAAGCGGGC GGGGCTGCAG 
GTCTGGAGAA TTGAGAAGCT GGAGCTGGTG CCGGTGCCCG AGAGCGCGTA TGGCAACTTC 
TACGTCGGGG ATGCCTACCT GGTGCTCCAC ACGACGCAGG CCAGCCGGGG CTTCACCTAC 
CGCCTGCACT TCTGGCTGGG AAAGGAGTGT ACTCAGGATG AAAGCACAGC AGCTGCCATC 
TTTACTGTTC AGATGGATGA CTATTTGGGT GGCAAACCTG TGCAGAACAG AGAACTTCAA 
GGCTATGAGT CTACGGATTT TGTTGGCTAC TTTAAAGGAG GTCTGAAATA CAAGGCTGGC 
GGTGTGGCGT CTGGACTCAA TCATGTGCTT ACAAATGACT TGACTGCTCA GAGGCTCCTG 
CATGTGAAAG GTCGGAGAGT CGTCAGGGCC ACGGAAGTTC CCCTAAGCTG GGACAGTTTC 
AACAAGGGTG ACTGCTTCAT CATTGACCTT GGCACTGAAA TTTACCAGTG GTGTGGATCT 
TCTTGCAACA AGTACGAGCG CCTGAAGGCC AGCCAGGTTG CCATCGGCAT TCGGGACAAT 
GAAAGGAAAG GCAGAGCTCA GCTGATTGTG GTAGAAGAAG GGAGTGAACC ATCAGAGCTT 
ACAAAGGTAT TAGGGGAAAA GCCAAAGCTT ACCCATGGAG AAGATGATGA TGACATCAAA 
GCAGATATAA CTAATAGGAA AATGGCTAAA CTCTACATGG TTTCAGATGC CAGTGGCTCC 
ATGAAAGTGA GTCTGGTGGC AGAAGAAAAC CCCTTCTCCA TGGCGATGCT TCTGTCTGAA 
GAATGCTTCA TTTTGGACCA CGGTGCTGCA AAACAGATTT TTGTATGGAA AGGTAAAGAT 
GCTAATCCCC AGGAGAGAAA GGCTGCCATG AAGACAGCTG AGGAATTCCT ACAGCAAATG 
AATTATTCTA CGAATACCCA AATTCAACTT CTTCCAGAAG GAGGTGAAAC ACCAATCTTC 
AAACAGTTCT TTAAGGACTG GAGAGATAGA GATCAGAGCG ATGGCTTCGG GAAAGTGTAT 
GTCACAGAAA AAGTGGCTCA CGTAAAACAA ATTCCATTTG ATGCCTCAAA ATTGCACAGC 
TCCCCACAAA TGGCAGCCCA GCATCACGTG GTGGATGACG GTTCTGGCAA AGTGCAGATT 
TGGCGTGTAG AAAACAACGG TAGGGTCGAA ATTGACCGAA ACTCGTATGG TGAATTCTAT 
GGTGGTGATT GCTACATTAT ACTTTACACT TATCCCAGAG GACAGATTAT CTACACCTGG 
CAAGGAGCAA ATGCCACACG GGATGAGCTG ACAACCTCCG ATTCCCGACT GTTCAGTTGG 
ATAGATCCCT CGGGGGATCA GGCTGTGCAG ATTCGAGTCT CCCAAGGCAA AGAACCTGCT 
CACCTGCTGA GTTTGTTCAA AGACAAACCG CTCATTATTT ACAAGAACGG AACATCAAAG 
AAAGAAGGTC AGGCACCAGC CCCCCCTATA CGCCTCTTTC AAGTCCGAAG AAACCTGGAT 
TCGTACACCA GAATTATGGA GGTAGATGTT GATGCAAACT CATTGAATTC CAATGATGTT 
TTTGTCCTGA AACTGCGACA AAATAATGGC TACATCTGGA TAGGAAAAGG CTCCACACAG 
GAGGAGGAGA AAGGAGCAGA GTACGTGGCA AGCGTCCTCA AATGCAAAAC TTCGACGATT 
CAGGAAGGCA AGGAACCAGA GGAGTTTTGG AATTCCCTTG GAGGGAAAAA AGACTACCAG 
ACCTCTCCTC TGCTAGAATC CCAGGCTGAA GACCATCCAC CTCGGCTTTA CGGCTGCTCC 
AACAAAACTG GAAGATTCAT TATTGAAGAG GTTCCAGGAG AGTTCACCCA GGATGATTTA 
GCAGAAGATG ATGTCATGCT GTTAGATGCT TGGGAACAGA TTTTTATTTG GATTGGAAAA 
GATGCCAATG AAGTTGAGAA ATCAGAATCT CTGAAGTCTG CCAAAATATA CCTTGAGACC 
GACCCTTCTG GAAGAGACAA GAGGACGCCA ATTGTCATCA TAAAACAGGG TCATGAGCCA 
CCTACTTTCA CAGGCTGGTT CCTGGGCTGG GATTCCAGCA GGTGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Expression of various scinderin domains in chromaffin cells indicates that this protein acts as a molecular switch in the control of actin filament dynamics and exocytosis.
Journal of neurochemistry92(4)780-9(2005 Feb)
Dumitrescu Pene T,Ros? SD,Lejen T,Marcu MG,Trifar? JM

Recombinant scinderin enhances exocytosis, an effect blocked by two scinderin-derived actin-binding peptides and PIP2.
Neuron17(2)287-96(1996 Aug)
Zhang L,Marcu MG,Nau-Staudt K,Trifar? JM

Molecular cloning and functional expression of chromaffin cell scinderin indicates that it belongs to the family of Ca(2+)-dependent F-actin severing proteins.
Molecular and cellular biochemistry141(2)153-65(1994 Dec)
Marcu MG,Rodr?guez del Castillo A,Vitale ML,Trifar? JM

Differential expression of bovine adseverin in adrenal gland revealed by in situ hybridization. Cloning of a cDNA for adseverin.
The Journal of biological chemistry269(8)5890-6(1994 Feb)
Nakamura S,Sakurai T,Nonomura Y

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

SCIN cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報