Gene Symbol | NPR2 |
Entrez Gene ID | 281357 |
Full Name | natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » NPR2 cDNA ORF clone
Gene Symbol | NPR2 |
Entrez Gene ID | 281357 |
Full Name | natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_024995443.1 | XP_024851211.1 | atrial natriuretic peptide receptor 2 isoform X2 |
NM_174126.2 | NP_776551.1 | atrial natriuretic peptide receptor 2 precursor |
XM_024995442.1 | XP_024851210.1 | atrial natriuretic peptide receptor 2 isoform X1 |
XM_024995444.1 | XP_024851212.1 | atrial natriuretic peptide receptor 2 isoform X3 |
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Adenine nucleotides decrease the apparent Km of endogenous natriuretic peptide receptors for GTP.
Antos LK, Potter LR
American journal of physiology. Endocrinology and metabolism293(6)E1756-63(2007 Dec)
Coupling of M3 acetylcholine receptor to Gq16 activates a natriuretic peptide receptor guanylyl cyclase.
Bruges G, Borges A, S?nchez de Villarroel S, Lippo de B?cemberg I, Francis de Toba G, Pl?ceres F, Gonz?lez de Alfonzo R, Alfonzo MJ
Journal of receptor and signal transduction research27(2-3)189-216(2007)
Characterization of a G protein-coupled guanylyl cyclase-B receptor from bovine tracheal smooth muscle.
Alfonzo MJ, de Aguilar EP, de Murillo AG, de Villarroel SS, de Alfonzo RG, Borges A, de Becemberg IL
Journal of receptor and signal transduction research26(4)269-97(2006)
[Detection of expression of a membrane form of the guanylate cyclase type of GC-B in cattle retina].
Shmukler BE, Zubov DV, Abdulaev NG
Bioorganicheskaia khimiia19(6)682-5(1993 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
ATP is not required for the initial activation of natriuretic peptide receptor A and B, but does increase activity over time by reducing the apparent K(m) for GTP.
Title: Adenine nucleotides decrease the apparent Km of endogenous natriuretic peptide receptors for GTP.
These data support the existence of a novel transducing cascade, involving Galpha(q16)beta gamma coupling M(3)AChR to NPR-GC.
Title: Coupling of M3 acetylcholine receptor to Gq16 activates a natriuretic peptide receptor guanylyl cyclase.
NPR-B is a highly regulated nano-machinery with domains acting at cross-talk points with other signal transducing cascades initiated by G protein-coupled receptors
Title: Characterization of a G protein-coupled guanylyl cyclase-B receptor from bovine tracheal smooth muscle.
The following NPR2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NPR2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa236922 | |
Clone ID Related Accession (Same CDS sequence) | XM_024995442.1 | |
Accession Version | XM_024995442.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3246bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | atrial natriuretic peptide receptor 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037335.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCACTGC CATCTCTCCT GCTGGTGGTG GCAGCCCTGG CAGGTGGGGT GCGTCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024851210.1 |
CDS | 786..4031 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024995442.1 |
1 | ATGGCACTGC CATCTCTCCT GCTGGTGGTG GCAGCCCTGG CAGGTGGGGT GCGTCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa236923 | |
Clone ID Related Accession (Same CDS sequence) | XM_024995443.1 | |
Accession Version | XM_024995443.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3171bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | atrial natriuretic peptide receptor 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037335.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCACTGC CATCTCTCCT GCTGGTGGTG GCAGCCCTGG CAGGTGGGGT GCGTCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024851211.1 |
CDS | 786..3956 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024995443.1 |
1 | ATGGCACTGC CATCTCTCCT GCTGGTGGTG GCAGCCCTGG CAGGTGGGGT GCGTCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa236924 | |
Clone ID Related Accession (Same CDS sequence) | XM_024995444.1 | |
Accession Version | XM_024995444.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3069bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | atrial natriuretic peptide receptor 2 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037335.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCACTGC CATCTCTCCT GCTGGTGGTG GCAGCCCTGG CAGGTGGGGT GCGTCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024851212.1 |
CDS | 785..3853 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024995444.1 |
1 | ATGGCACTGC CATCTCTCCT GCTGGTGGTG GCAGCCCTGG CAGGTGGGGT GCGTCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa43847 | |
Clone ID Related Accession (Same CDS sequence) | NM_174126.2 | |
Accession Version | NM_174126.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3144bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Bos taurus(cattle) | |
Product | atrial natriuretic peptide receptor 2 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L26359.1. On or before Aug 31, 2013 this sequence version replaced XM_005210146.1, XM_003586399.1, NM_174126.1. ##Evidence-Data-START## Transcript exon combination :: L26359.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCACTGC CATCTCTCCT GCTGGTGGTG GCAGCCCTGG CAGGTGGGGT GCGTCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776551.1 |
CDS | 1..3144 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174126.2 |
1 | ATGGCACTGC CATCTCTCCT GCTGGTGGTG GCAGCCCTGG CAGGTGGGGT GCGTCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A whole-genome assembly of the domestic cow, Bos taurus. |
Adenine nucleotides decrease the apparent Km of endogenous natriuretic peptide receptors for GTP. |
Coupling of M3 acetylcholine receptor to Gq16 activates a natriuretic peptide receptor guanylyl cyclase. |
Characterization of a G protein-coupled guanylyl cyclase-B receptor from bovine tracheal smooth muscle. |
[Detection of expression of a membrane form of the guanylate cyclase type of GC-B in cattle retina]. |