Gene Symbol | INS |
Entrez Gene ID | 280829 |
Full Name | insulin |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » INS cDNA ORF clone
Gene Symbol | INS |
Entrez Gene ID | 280829 |
Full Name | insulin |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_015461330.1 | XP_015316816.1 | insulin isoform X1 |
XM_015461330.2 | XP_015316816.2 | insulin isoform X1 |
NM_173926.2 | NP_776351.2 | insulin preproprotein |
NM_001185126.1 | NP_001172055.1 | insulin preproprotein |
Top-Down Charge Transfer Dissociation (CTD) of Gas-Phase Insulin: Evidence of a One-Step, Two-Electron Oxidation Mechanism.
Li P, Kreft I, Jackson GP
Journal of the American Society for Mass Spectrometry(2017 Aug)
Insulin signaling and skeletal muscle atrophy and autophagy in transition dairy cows either overfed energy or fed a controlled energy diet prepartum.
Mann S, Abuelo A, Nydam DV, Leal Yepes FA, Overton TR, Wakshlag JJ
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology186(4)513-25(2016 May)
Interaction of partially denatured insulin with a DSPC floating lipid bilayer.
Dennison AJ, Jones RA, Staniforth RA, Parnell AJ
Soft matter12(3)824-9(2016 Jan)
Gene expression profiling of hormonal regulation related to the residual feed intake of Holstein cattle.
Xi YM, Yang Z, Wu F, Han ZY, Wang GL
Biochemical and biophysical research communications465(1)19-25(2015 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Insulin signaling role in skeletal muscle atrophy and autophagy in in transition and postpartum period
Title: Insulin signaling and skeletal muscle atrophy and autophagy in transition dairy cows either overfed energy or fed a controlled energy diet prepartum.
Structural changes consistent with protein partitioning to the membrane interior and adsorption to a gel phase model lipid bilayer were observed under conditions where the native fold of the protein is significantly destabilised.
Title: Interaction of partially denatured insulin with a DSPC floating lipid bilayer.
Hormonal gene expression involved in residual feed intake in dairy cows may be related to the molecular regulation of the leptin-NPY and insulin signaling pathways.
Title: Gene expression profiling of hormonal regulation related to the residual feed intake of Holstein cattle.
increased sensitivity to glucose clearance and skeletal muscle insulin signaling during dietary restriction
Title: Insulin secretion and signaling in response to dietary restriction and subsequent re-alimentation in cattle.
Differences between human and bovine insulin kinetics under shear
Title: Comparison of Human and Bovine Insulin Amyloidogenesis under Uniform Shear.
The following INS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the INS cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa231829 | |
Clone ID Related Accession (Same CDS sequence) | XM_015461330.2 | |
Accession Version | XM_015461330.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | insulin isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037356.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_015461330.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCCCAG GCAGGGCCAG GCGGAGGACT TCACCCCCAG CGGTGCGAGG GAACAGCTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015316816.2 |
CDS | 192..857 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015461330.2 |
1 | ATGGGCCCAG GCAGGGCCAG GCGGAGGACT TCACCCCCAG CGGTGCGAGG GAACAGCTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa34962 | |
Clone ID Related Accession (Same CDS sequence) | NM_173926.2 , NM_001185126.1 | |
Accession Version | NM_173926.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 318bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-21 | |
Organism | Bos taurus(cattle) | |
Product | insulin preproprotein | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EV652245.1. On Jun 5, 2010 this sequence version replaced NM_173926.1. Transcript Variant: This transcript (1) represents the shorter variant. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EV652245.1, EH378970.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145444, SAMN03145455 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCCTGT GGACACGCCT GGCGCCCCTG CTGGCCCTGC TGGCGCTCTG GGCCCCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776351.2 |
CDS | 66..383 |
Translation |
Target ORF information:
Target ORF information:
|
NM_173926.2 |
1 | ATGGCCCTGT GGACACGCCT GGCGCCCCTG CTGGCCCTGC TGGCGCTCTG GGCCCCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa34962 | |
Clone ID Related Accession (Same CDS sequence) | NM_173926.2 , NM_001185126.1 | |
Accession Version | NM_001185126.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 318bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-21 | |
Organism | Bos taurus(cattle) | |
Product | insulin preproprotein | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EV652245.1 and EH379095.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EV653508.1, EH379298.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145444, SAMN03145445 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCCTGT GGACACGCCT GGCGCCCCTG CTGGCCCTGC TGGCGCTCTG GGCCCCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001172055.1 |
CDS | 82..399 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001185126.1 |
1 | ATGGCCCTGT GGACACGCCT GGCGCCCCTG CTGGCCCTGC TGGCGCTCTG GGCCCCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa89145 | |
Clone ID Related Accession (Same CDS sequence) | XM_015461330.1 | |
Accession Version | XM_015461330.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | insulin isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104648.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCCCAG GCAGGGCCAG GCGGAGGACT TCACCCCCAG CGGTGCGAGG GGACAGCTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015316816.1 |
CDS | 180..845 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015461330.1 |
1 | ATGGGCCCAG GCAGGGCCAG GCGGAGGACT TCACCCCCAG CGGTGCGAGG GGACAGCTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Top-Down Charge Transfer Dissociation (CTD) of Gas-Phase Insulin: Evidence of a One-Step, Two-Electron Oxidation Mechanism. |
Insulin signaling and skeletal muscle atrophy and autophagy in transition dairy cows either overfed energy or fed a controlled energy diet prepartum. |
Interaction of partially denatured insulin with a DSPC floating lipid bilayer. |
Gene expression profiling of hormonal regulation related to the residual feed intake of Holstein cattle. |