PYR1 cDNA ORF clone, Arabidopsis thaliana(thale cress)

Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.
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Nature402(6763)769-77(1999 Dec)

Data indicate that bscisic acid (ABA) signaling is repressed by group A type 2C protein phosphatases (PP2Cs), and then ABA binds to its receptor of the ACTIN RESISTANCE1 (PYR1), PYR1-LIKE (PYL), and REGULATORY COMPONENTS OF ABA RECEPTORS (RCAR) family, which, in turn, inhibits PP2Cs and activates downstream ABA signaling.
Title: A Novel Chemical Inhibitor of ABA Signaling Targets All ABA Receptors.

study suggests both nuclear and cytoplasmic PYR1 participate in the control of ABA signal transduction
Title: Production of ABA responses requires both the nuclear and cytoplasmic functional involvement of PYR1.

RSL1-PYL4 and RSL1-PYR1 interaction is localized to plasma membrane. RSL1 promoted PYL4 and PYR1 degradation in vivo and mediated in vitro ubiquitylation of the receptors.
Title: The single-subunit RING-type E3 ubiquitin ligase RSL1 targets PYL4 and PYR1 ABA receptors in plasma membrane to modulate abscisic acid signaling.

Pyr1 receptor contributes to ozone, reduced air humidity and darkness induced stomatal regulation.
Title: PYR/RCAR receptors contribute to ozone-, reduced air humidity-, darkness-, and CO2-induced stomatal regulation.

findings are generally consistent with the competitive-interaction model for PYR1 but highlight dynamical contributions of the PYR1 structure in mediating interaction selectivity
Title: Molecular mechanisms in the activation of abscisic acid receptor PYR1.