Gene Symbol | SPI2 |
Entrez Gene ID | 100065158 |
Full Name | alpha-1-antitrypsin |
Gene Type | protein-coding |
Organism | Equus caballus(horse) |
ORF » Species Summary » Equus caballus » SPI2 cDNA ORF clone
Gene Symbol | SPI2 |
Entrez Gene ID | 100065158 |
Full Name | alpha-1-antitrypsin |
Gene Type | protein-coding |
Organism | Equus caballus(horse) |
mRNA | Protein | Name |
---|---|---|
XM_023627719.1 | XP_023483487.1 | alpha-1-antiproteinase 2 isoform X1 |
XM_014735593.1 | XP_014591079.1 | alpha-1-antiproteinase 2 isoform X1 |
XM_014735594.1 | XP_014591080.1 | alpha-1-antiproteinase 2 isoform X1 |
NM_001114533.1 | NP_001108005.1 | alpha-1-antiproteinase 2 precursor |
Circulating nucleosomes and elastase ?1-antitrypsin complexes and the novel thrombosis susceptibility locus SLC44A2.
Heestermans M, Cunha ML, Reitsma PH, Zeerleder SS, Middeldorp S, van Vlijmen BJ
Thrombosis research1428-10(2016 Jun)
Annotation of the Protein Coding Regions of the Equine Genome.
Hestand MS, Kalbfleisch TS, Coleman SJ, Zeng Z, Liu J, Orlando L, MacLeod JN
PloS one10(6)e0124375(2015)
Analysis of the alpha-1-antitrypsin deficient alleles M3S, MZ, and ZZ by biochemical and molecular methods: a family study.
Calapo?lu M, De?er O, Balaban F, Sahin Calapo?lu N, B?lb?l Y, Burling K
Biochemical genetics47(1-2)33-41(2009 Feb)
The equine major plasma serpin multigene family: partial characterization including sequence of the reactive-site regions.
Patterson SD, Bell K, Shaw DC
Biochemical genetics29(9-10)477-99(1991 Oct)
The carbohydrate side chains of the major plasma serpins of horse and wallaby: analyses of enzymatic and chemically treated (including 'Smith degradation') protein blots by lectin binding.
Patterson SD, Bell K
Biochemistry international20(3)429-36(1990)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Although circulating nucleosomes and elastase - alpha 1-antitrypsin complexes are at present the best characterized biomarkers for neutrophil extracellular traps formation and neutrophil activation, their lack of association with rs2288904 genotype does not exclude a role for SLC44A2 in neutrophil activation (and possibly NET formation) in Venous Thromboembolism.
Title: Circulating nucleosomes and elastase ?1-antitrypsin complexes and the novel thrombosis susceptibility locus SLC44A2.
Study characterized one of the normal M3 variants and two deficient S and Z variants in a Turkish family, and determined average serum concentrations and reference intervals in both the phenotypic variants and healthy controls.
Title: Analysis of the alpha-1-antitrypsin deficient alleles M3S, MZ, and ZZ by biochemical and molecular methods: a family study.
The following SPI2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SPI2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OHb00048 | |
Clone ID Related Accession (Same CDS sequence) | NM_001114533.1 | |
Accession Version | NM_001114533.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1266bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Equus caballus(horse) | |
Product | alpha-1-antiproteinase 2 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF034077.2. On Feb 13, 2008 this sequence version replaced XM_001495835.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2743238 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCATCCT CCGTCCCATG GTGCCTCCTC CTGCTGGCAG GCCTGTGCTG CCTGGTCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001108005.1 |
CDS | 13..1278 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001114533.1 |
1 | ATGCCATCCT CCGTCCCATG GTGCCTCCTC CTGCTGGCAG GCCTGTGCTG CCTGGTCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHb13720 | |
Clone ID Related Accession (Same CDS sequence) | XM_014735593.1 , XM_014735594.1 | |
Accession Version | XM_014735593.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1266bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-11-19 | |
Organism | Equus caballus(horse) | |
Product | alpha-1-antiproteinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_001867395.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Equus caballus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATCCT CCGTCACATG GTGCCTCCTC CTGCTGGCAG GCCTGTGCTG CCTGGTCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014591079.1 |
CDS | 106..1371 |
Translation |
Target ORF information:
Target ORF information:
|
XM_014735593.1 |
1 | ATGCCATCCT CCGTCACATG GTGCCTCCTC CTGCTGGCAG GCCTGTGCTG CCTGGTCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHb13720 | |
Clone ID Related Accession (Same CDS sequence) | XM_014735593.1 , XM_014735594.1 | |
Accession Version | XM_014735594.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1266bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-11-19 | |
Organism | Equus caballus(horse) | |
Product | alpha-1-antiproteinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_001867395.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Equus caballus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATCCT CCGTCACATG GTGCCTCCTC CTGCTGGCAG GCCTGTGCTG CCTGGTCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014591080.1 |
CDS | 146..1411 |
Translation |
Target ORF information:
Target ORF information:
|
XM_014735594.1 |
1 | ATGCCATCCT CCGTCACATG GTGCCTCCTC CTGCTGGCAG GCCTGTGCTG CCTGGTCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHb58165 | |
Clone ID Related Accession (Same CDS sequence) | XM_023627719.1 | |
Accession Version | XM_023627719.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1266bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-01-22 | |
Organism | Equus caballus(horse) | |
Product | alpha-1-antiproteinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_009167.3) and transcript sequence (GDHK01056984.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Equus caballus Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 480 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## |
1 | ATGCCATCCT CCGTCACATG GTGCCTCCTC CTGCTGGCAG GCCTGTGCTG CCTGGTCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_023483487.1 |
CDS | 277..1542 |
Translation |
Target ORF information:
Target ORF information:
|
XM_023627719.1 |
1 | ATGCCATCCT CCGTCACATG GTGCCTCCTC CTGCTGGCAG GCCTGTGCTG CCTGGTCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Circulating nucleosomes and elastase ?1-antitrypsin complexes and the novel thrombosis susceptibility locus SLC44A2. |
Annotation of the Protein Coding Regions of the Equine Genome. |
Analysis of the alpha-1-antitrypsin deficient alleles M3S, MZ, and ZZ by biochemical and molecular methods: a family study. |
The equine major plasma serpin multigene family: partial characterization including sequence of the reactive-site regions. |
The carbohydrate side chains of the major plasma serpins of horse and wallaby: analyses of enzymatic and chemically treated (including 'Smith degradation') protein blots by lectin binding. |