MAPK14 cDNA ORF clone, Canis lupus familiaris(Dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAPK14
Entrez Gene ID	403856
Full Name	mitogen-activated protein kinase 14
General protein information	Preferred Names mitogen-activated protein kinase 14 Names mitogen-activated protein kinase 14 MAP kinase 14 MAP kinase p38 alpha MAPK 14 mitogen-activated protein kinase p38 alpha p38 alpha/Mxi2 p38 mitogen activated protein kinase
Gene Type	protein-coding
Organism	Canis lupus familiaris(Dog)

mRNA and Protein(s)

mRNA	Protein	Name
XM_014118022.2	XP_013973497.1	mitogen-activated protein kinase 14 isoform X2
NM_001003206.1	NP_001003206.1	mitogen-activated protein kinase 14
XM_005627027.3	XP_005627084.1	mitogen-activated protein kinase 14 isoform X1
XM_005627027.2	XP_005627084.1	mitogen-activated protein kinase 14 isoform X1
XM_014118022.1	XP_013973497.1	mitogen-activated protein kinase 14 isoform X2

Pathways from BioSystems

Homologies

Homo sapiens (human)	MAPK14	NP_001306.1
Saccharomyces cerevisiae (baker's yeast)	HOG1	NP_013214.1
Neurospora crassa	NCU07024	XP_962163.2
Canis lupus familiaris (dog)	MAPK14	NP_001003206.1
Rattus norvegicus (Norway rat)	Mapk14	NP_112282.2
Kluyveromyces lactis	KLLA0F20053g	XP_455981.1
Eremothecium gossypii	AGOS_AGR048C	NP_986713.1
Bos taurus (cattle)	MAPK14	NP_001095644.1
Drosophila melanogaster (fruit fly)	Mpk2	NP_001163711.1
Caenorhabditis elegans (roundworm)	pmk-1	NP_501365.1
Magnaporthe oryzae (rice blast fungus)	MGG_01822	XP_003714838.1
Oryza sativa (rice)	Os03g0285800	NP_001049770.1
Xenopus tropicalis (tropical clawed frog)	mapk14	NP_001005824.1
	LOC718976	XP_001112423.2
Mus musculus (house mouse)	Mapk14	NP_001161980.1
Gallus gallus (chicken)	MAPK14	XP_001232616.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012148	XP_320380.4
Schizosaccharomyces pombe (fission yeast)	sty1	NP_592843.1
Pan troglodytes (chimpanzee)	MAPK14	NP_001009065.1
Danio rerio (zebrafish)	mapk14a	NP_571797.1
Drosophila melanogaster (fruit fly)	p38b	NP_477361.1
Arabidopsis thaliana (thale cress)	MPK3	NP_190150.1

Gene Ontology
Bibliography

Related articles in PubMed

Role of Src signal transduction pathways in scatter factor-mediated cellular protection.
Fan S, Meng Q, Laterra JJ, Rosen EM
The Journal of biological chemistry284(12)7561-77(2009 Mar)

Bcl-2 Phosphorylation by p38 MAPK: identification of target sites and biologic consequences.
De Chiara G, Marcocci ME, Torcia M, Lucibello M, Rosini P, Bonini P, Higashimoto Y, Damonte G, Armirotti A, Amodei S, Palamara AT, Russo T, Garaci E, Cozzolino F
The Journal of biological chemistry281(30)21353-61(2006 Jul)

Rho/ROCK-dependent pseudopodial protrusion and cellular blebbing are regulated by p38 MAPK in tumour cells exhibiting autocrine c-Met activation.
Jia Z, Vadnais J, Lu ML, No?l J, Nabi IR
Biology of the cell98(6)337-51(2006 Jun)

A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase.
Blanco-Aparicio C, Torres J, Pulido R
The Journal of cell biology147(6)1129-36(1999 Dec)

p38 mitogen-activated protein kinase expression and activation in smooth muscle.
Hedges JC, Yamboliev IA, Ngo M, Horowitz B, Adam LP, Gerthoffer WT
The American journal of physiology275(2 Pt 1)C527-34(1998 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

as a mediator of SF- and Src-stimulated NF-kappaB activity. Finally, the Src/Rac1/MKK3/6/p38 and Src/TAK1/NF-kappaB-inducing kinase pathways exhibited cross-talk at the level of MKK3.
Title: Role of Src signal transduction pathways in scatter factor-mediated cellular protection.

Bcl-2 phosphorylation by activated p38 MAPK is a key event in the early induction of apoptosis under conditions of cellular stress
Title: Bcl-2 Phosphorylation by p38 MAPK: identification of target sites and biologic consequences.

The localized activation of an autocrine HGF/c-Met loop regulates Rho/ROCK activation of p38 MAPK signalling to stimulate both membrane blebbing and pseudopod formation.
Title: Rho/ROCK-dependent pseudopodial protrusion and cellular blebbing are regulated by p38 MAPK in tumour cells exhibiting autocrine c-Met activation.

The following MAPK14 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAPK14 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCe00080	NM_001003206.1 Latest version!	Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OCe14900	XM_005627027.3 Latest version!	Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OCe39318	XM_014118022.2 Latest version!	Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00
View Old Accession Versions >>
OCe14900	XM_005627027.2	Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OCe39318	XM_014118022.1	Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAPK14 ( NM_001003206.1 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> NP_001003206.1 Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), mRNA.

Price & Availability↑

CloneID	OCe00080
Clone ID Related Accession (Same CDS sequence)	NM_001003206.1
Accession Version	NM_001003206.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Canis lupus familiaris(dog)
Product	mitogen-activated protein kinase 14
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF003597.1. ##Evidence-Data-START## Transcript exon combination :: AF003597.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END##

ATGTCTCAGG AAAGGCCCAC GTTCTACCGG CAGGAGCTGA ATAAGACAAT CTGGGAGGTG 
CCCGAGCGTT ACCAGAACCT GTCCCCGGTG GGCTCCGGCG CCTACGGCTC CGTGTGTGCT 
GCTTTTGACA CAAAAACTGG GTTACGTGTG GCAGTCAAGA AGCTCTCCAG ACCATTTCAG 
TCCATCATTC ATGCCAAAAG GACCTACAGA GAACTGCGGT TACTGAAACA TATGAAACAT 
GAAAATGTGA TTGGTCTCTT GGATGTTTTT ACACCTGCAA GGTCTCTGGA GGAATTCAAT 
GATGTGTATC TGGTGACCCA TCTTATGGGA GCAGATCTGA ACAACATTGT GAAATGTCAG 
AAGCTTACGG ATGACCATGT TCAGTTCCTT ATCTACCAAA TTCTCCGAGG TCTCAAGTAT 
ATACATTCAG CTGACATAAT TCACAGGGAC CTAAAACCTA GCAATCTAGC TGTGAATGAA 
GACTGTGAGC TGAAGATCCT GGACTTTGGA CTGGCCCGAC ATACAGATGA TGAAATGACA 
GGCTATGTGG CTACCAGGTG GTACAGGGCT CCTGAGATAA TGCTGAACTG GATGCATTAC 
AACCAGACAG TTGATATTTG GTCAGTGGGA TGCATAATGG CCGAACTGTT GACTGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTGAT CAGTTGAAGC TCATTTTAAG ACTCGTTGGA 
ACCCCAGGGG CTGATCTTTT GAAGAAAATC TCCTCAGAGT CTGCAAGAAA CTACATTCAG 
TCTTTGACCC AGATGCCGAA GATGAACTTT GCAAATGTAT TTATTGGTGC CAATCCCTTG 
GCTGTCGACT TGCTGGAGAA GATGCTTGTA TTGGACTCAG ACAAGAGAAT TACAGCAGCC 
CAAGCCCTCG CACATGCCTA CTTTGCTCAG TACCATGATC CAGATGATGA ACCAGTGGCT 
GATCCTTACG ATCAGTCCTT TGAAAGCAGG GACCTCCTTA TAGATGAATG GAAAAGCCTG 
ACCTACGATG AAGTCGTCAG CTTTGTGCCG CCACCCCTTG ACCAAGAAGA GATGGAGTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003206.1
CDS	1..1083
Translation	MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGADLLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVVSFVPPPLDQEEMES

Target ORF information:

RefSeq Version	NM_001003206.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003206.1

ORF Insert Sequence:

ATGTCTCAGG AAAGGCCCAC GTTCTACCGG CAGGAGCTGA ATAAGACAAT CTGGGAGGTG 
CCCGAGCGTT ACCAGAACCT GTCCCCGGTG GGCTCCGGCG CCTACGGCTC CGTGTGTGCT 
GCTTTTGACA CAAAAACTGG GTTACGTGTG GCAGTCAAGA AGCTCTCCAG ACCATTTCAG 
TCCATCATTC ATGCCAAAAG GACCTACAGA GAACTGCGGT TACTGAAACA TATGAAACAT 
GAAAATGTGA TTGGTCTCTT GGATGTTTTT ACACCTGCAA GGTCTCTGGA GGAATTCAAT 
GATGTGTATC TGGTGACCCA TCTTATGGGA GCAGATCTGA ACAACATTGT GAAATGTCAG 
AAGCTTACGG ATGACCATGT TCAGTTCCTT ATCTACCAAA TTCTCCGAGG TCTCAAGTAT 
ATACATTCAG CTGACATAAT TCACAGGGAC CTAAAACCTA GCAATCTAGC TGTGAATGAA 
GACTGTGAGC TGAAGATCCT GGACTTTGGA CTGGCCCGAC ATACAGATGA TGAAATGACA 
GGCTATGTGG CTACCAGGTG GTACAGGGCT CCTGAGATAA TGCTGAACTG GATGCATTAC 
AACCAGACAG TTGATATTTG GTCAGTGGGA TGCATAATGG CCGAACTGTT GACTGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTGAT CAGTTGAAGC TCATTTTAAG ACTCGTTGGA 
ACCCCAGGGG CTGATCTTTT GAAGAAAATC TCCTCAGAGT CTGCAAGAAA CTACATTCAG 
TCTTTGACCC AGATGCCGAA GATGAACTTT GCAAATGTAT TTATTGGTGC CAATCCCTTG 
GCTGTCGACT TGCTGGAGAA GATGCTTGTA TTGGACTCAG ACAAGAGAAT TACAGCAGCC 
CAAGCCCTCG CACATGCCTA CTTTGCTCAG TACCATGATC CAGATGATGA ACCAGTGGCT 
GATCCTTACG ATCAGTCCTT TGAAAGCAGG GACCTCCTTA TAGATGAATG GAAAAGCCTG 
ACCTACGATG AAGTCGTCAG CTTTGTGCCG CCACCCCTTG ACCAAGAAGA GATGGAGTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAPK14 ( XM_005627027.3 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_005627084.1 Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe14900
Clone ID Related Accession (Same CDS sequence)	XM_005627027.3 , XM_005627027.2
Accession Version	XM_005627027.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	mitogen-activated protein kinase 14 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006594.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005627027.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ATAAGACAAT CTGGGAGGTG 
CCCGAGCGTT ACCAGAACCT GTCCCCGGTG GGCTCCGGCG CCTACGGCTC CGTGTGTGCT 
GCTTTTGACA CAAAAACTGG GTTACGTGTG GCAGTCAAGA AGCTCTCCAG ACCATTTCAG 
TCCATTATTC ATGCCAAAAG GACCTACAGA GAACTGCGGT TACTGAAACA TATGAAACAT 
GAAAATGTGA TTGGTCTCTT GGATGTTTTT ACACCTGCAA GGTCTCTGGA GGAATTCAAT 
GATGTGTATC TGGTGACCCA TCTTATGGGA GCAGATCTGA ACAACATTGT GAAATGTCAG 
AAGCTTACGG ATGACCATGT TCAGTTCCTT ATCTACCAAA TTCTCCGAGG TCTCAAGTAT 
ATACATTCAG CTGACATAAT TCACAGGGAC CTAAAACCTA GCAATCTAGC TGTGAATGAA 
GACTGTGAGC TGAAGATCTT GGACTTTGGA CTGGCCCGAC ATACAGATGA TGAAATGACA 
GGCTATGTGG CTACCAGGTG GTACAGGGCT CCTGAGATAA TGCTGAACTG GATGCATTAC 
AACCAGACAG TTGATATTTG GTCAGTGGGA TGCATAATGG CCGAACTGTT GACTGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTAAC CAGCTTCAGC AGATTATGCG TCTGACGGGG 
ACCCCCCCTG CTTATCTCAT TAACAGGATG CCAAGCCATG AGGCAAGAAA CTACATTCAG 
TCTTTGACCC AGATGCCGAA AATGAACTTT GCAAATGTAT TTATTGGTGC CAATCCCTTG 
GCTGTCGACT TGCTGGAGAA GATGCTTGTA TTGGACTCAG ACAAGAGAAT TACAGCAGCC 
CAAGCCCTCG CACATGCCTA CTTTGCTCAG TACCATGATC CAGATGATGA ACCAGTGGCT 
GATCCTTACG ATCAGTCCTT TGAAAGCAGG GACCTCCTTA TAGATGAATG GAAAAGCCTG 
ACCTACGATG AAGTCGTCAG CTTTGTGCCG CCACCCCTTG ACCAAGAAGA GATGGAGTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005627084.1
CDS	385..1467
Translation	MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVVSFVPPPLDQEEMES

Target ORF information:

RefSeq Version	XM_005627027.3
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005627027.3

ORF Insert Sequence:

ATGTCTCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ATAAGACAAT CTGGGAGGTG 
CCCGAGCGTT ACCAGAACCT GTCCCCGGTG GGCTCCGGCG CCTACGGCTC CGTGTGTGCT 
GCTTTTGACA CAAAAACTGG GTTACGTGTG GCAGTCAAGA AGCTCTCCAG ACCATTTCAG 
TCCATTATTC ATGCCAAAAG GACCTACAGA GAACTGCGGT TACTGAAACA TATGAAACAT 
GAAAATGTGA TTGGTCTCTT GGATGTTTTT ACACCTGCAA GGTCTCTGGA GGAATTCAAT 
GATGTGTATC TGGTGACCCA TCTTATGGGA GCAGATCTGA ACAACATTGT GAAATGTCAG 
AAGCTTACGG ATGACCATGT TCAGTTCCTT ATCTACCAAA TTCTCCGAGG TCTCAAGTAT 
ATACATTCAG CTGACATAAT TCACAGGGAC CTAAAACCTA GCAATCTAGC TGTGAATGAA 
GACTGTGAGC TGAAGATCTT GGACTTTGGA CTGGCCCGAC ATACAGATGA TGAAATGACA 
GGCTATGTGG CTACCAGGTG GTACAGGGCT CCTGAGATAA TGCTGAACTG GATGCATTAC 
AACCAGACAG TTGATATTTG GTCAGTGGGA TGCATAATGG CCGAACTGTT GACTGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTAAC CAGCTTCAGC AGATTATGCG TCTGACGGGG 
ACCCCCCCTG CTTATCTCAT TAACAGGATG CCAAGCCATG AGGCAAGAAA CTACATTCAG 
TCTTTGACCC AGATGCCGAA AATGAACTTT GCAAATGTAT TTATTGGTGC CAATCCCTTG 
GCTGTCGACT TGCTGGAGAA GATGCTTGTA TTGGACTCAG ACAAGAGAAT TACAGCAGCC 
CAAGCCCTCG CACATGCCTA CTTTGCTCAG TACCATGATC CAGATGATGA ACCAGTGGCT 
GATCCTTACG ATCAGTCCTT TGAAAGCAGG GACCTCCTTA TAGATGAATG GAAAAGCCTG 
ACCTACGATG AAGTCGTCAG CTTTGTGCCG CCACCCCTTG ACCAAGAAGA GATGGAGTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAPK14 ( XM_005627027.2 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_005627084.1 Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe14900
Clone ID Related Accession (Same CDS sequence)	XM_005627027.3 , XM_005627027.2
Accession Version	XM_005627027.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	mitogen-activated protein kinase 14 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726081.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_005627027.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ATAAGACAAT CTGGGAGGTG 
CCCGAGCGTT ACCAGAACCT GTCCCCGGTG GGCTCCGGCG CCTACGGCTC CGTGTGTGCT 
GCTTTTGACA CAAAAACTGG GTTACGTGTG GCAGTCAAGA AGCTCTCCAG ACCATTTCAG 
TCCATTATTC ATGCCAAAAG GACCTACAGA GAACTGCGGT TACTGAAACA TATGAAACAT 
GAAAATGTGA TTGGTCTCTT GGATGTTTTT ACACCTGCAA GGTCTCTGGA GGAATTCAAT 
GATGTGTATC TGGTGACCCA TCTTATGGGA GCAGATCTGA ACAACATTGT GAAATGTCAG 
AAGCTTACGG ATGACCATGT TCAGTTCCTT ATCTACCAAA TTCTCCGAGG TCTCAAGTAT 
ATACATTCAG CTGACATAAT TCACAGGGAC CTAAAACCTA GCAATCTAGC TGTGAATGAA 
GACTGTGAGC TGAAGATCTT GGACTTTGGA CTGGCCCGAC ATACAGATGA TGAAATGACA 
GGCTATGTGG CTACCAGGTG GTACAGGGCT CCTGAGATAA TGCTGAACTG GATGCATTAC 
AACCAGACAG TTGATATTTG GTCAGTGGGA TGCATAATGG CCGAACTGTT GACTGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTAAC CAGCTTCAGC AGATTATGCG TCTGACGGGG 
ACCCCCCCTG CTTATCTCAT TAACAGGATG CCAAGCCATG AGGCAAGAAA CTACATTCAG 
TCTTTGACCC AGATGCCGAA AATGAACTTT GCAAATGTAT TTATTGGTGC CAATCCCTTG 
GCTGTCGACT TGCTGGAGAA GATGCTTGTA TTGGACTCAG ACAAGAGAAT TACAGCAGCC 
CAAGCCCTCG CACATGCCTA CTTTGCTCAG TACCATGATC CAGATGATGA ACCAGTGGCT 
GATCCTTACG ATCAGTCCTT TGAAAGCAGG GACCTCCTTA TAGATGAATG GAAAAGCCTG 
ACCTACGATG AAGTCGTCAG CTTTGTGCCG CCACCCCTTG ACCAAGAAGA GATGGAGTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005627084.1
CDS	407..1489
Translation	MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVVSFVPPPLDQEEMES

Target ORF information:

RefSeq Version	XM_005627027.2
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005627027.2

ORF Insert Sequence:

ATGTCTCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ATAAGACAAT CTGGGAGGTG 
CCCGAGCGTT ACCAGAACCT GTCCCCGGTG GGCTCCGGCG CCTACGGCTC CGTGTGTGCT 
GCTTTTGACA CAAAAACTGG GTTACGTGTG GCAGTCAAGA AGCTCTCCAG ACCATTTCAG 
TCCATTATTC ATGCCAAAAG GACCTACAGA GAACTGCGGT TACTGAAACA TATGAAACAT 
GAAAATGTGA TTGGTCTCTT GGATGTTTTT ACACCTGCAA GGTCTCTGGA GGAATTCAAT 
GATGTGTATC TGGTGACCCA TCTTATGGGA GCAGATCTGA ACAACATTGT GAAATGTCAG 
AAGCTTACGG ATGACCATGT TCAGTTCCTT ATCTACCAAA TTCTCCGAGG TCTCAAGTAT 
ATACATTCAG CTGACATAAT TCACAGGGAC CTAAAACCTA GCAATCTAGC TGTGAATGAA 
GACTGTGAGC TGAAGATCTT GGACTTTGGA CTGGCCCGAC ATACAGATGA TGAAATGACA 
GGCTATGTGG CTACCAGGTG GTACAGGGCT CCTGAGATAA TGCTGAACTG GATGCATTAC 
AACCAGACAG TTGATATTTG GTCAGTGGGA TGCATAATGG CCGAACTGTT GACTGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTAAC CAGCTTCAGC AGATTATGCG TCTGACGGGG 
ACCCCCCCTG CTTATCTCAT TAACAGGATG CCAAGCCATG AGGCAAGAAA CTACATTCAG 
TCTTTGACCC AGATGCCGAA AATGAACTTT GCAAATGTAT TTATTGGTGC CAATCCCTTG 
GCTGTCGACT TGCTGGAGAA GATGCTTGTA TTGGACTCAG ACAAGAGAAT TACAGCAGCC 
CAAGCCCTCG CACATGCCTA CTTTGCTCAG TACCATGATC CAGATGATGA ACCAGTGGCT 
GATCCTTACG ATCAGTCCTT TGAAAGCAGG GACCTCCTTA TAGATGAATG GAAAAGCCTG 
ACCTACGATG AAGTCGTCAG CTTTGTGCCG CCACCCCTTG ACCAAGAAGA GATGGAGTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAPK14 ( XM_014118022.2 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_013973497.1 Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OCe39318
Clone ID Related Accession (Same CDS sequence)	XM_014118022.2 , XM_014118022.1
Accession Version	XM_014118022.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 924bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	mitogen-activated protein kinase 14 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006594.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_014118022.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ATAAGACAAT CTGGGAGGTG 
CCCGAGCGTT ACCAGAACCT GTCCCCGGTG GGCTCCGGCG CCTACGGCTC CGTGTGTGCT 
GCTTTTGACA CAAAAACTGG GTTACGTGTG GCAGTCAAGA AGCTCTCCAG ACCATTTCAG 
TCCATTATTC ATGCCAAAAG GACCTACAGA GAACTGCGGT TACTGAAACA TATGAAACAT 
GAAAATGTGA TTGGTCTCTT GGATGTTTTT ACACCTGCAA GGTCTCTGGA GGAATTCAAT 
GATGTGTATC TGGTGACCCA TCTTATGGGA GCAGATCTGA ACAACATTGT GAAATGTCAG 
AAGCTTACGG ATGACCATGT TCAGTTCCTT ATCTACCAAA TTCTCCGAGG TCTCAAGTAT 
ATACATTCAG CTGACATAAT TCACAGGGAC CTAAAACCTA GCAATCTAGC TGTGAATGAA 
GACTGTGAGC TGAAGATCTT GGACTTTGGA CTGGCCCGAC ATACAGATGA TGAAATGACA 
GGCTATGTGG CTACCAGGTG GTACAGGGCT CCTGAGATAA TGCTGAACTG GATGCATTAC 
AACCAGACAG TTGATATTTG GTCAGTGGGA TGCATAATGG CCGAACTGTT GACTGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTGAT CAGTTGAAGC TCATTTTAAG ACTCGTTGGA 
ACCCCAGGGG CTGATCTTTT GAAGAAAATC TCCTCAGAGT CTCTGTCGAC TTGCTGGAGA 
AGATGCTTGT ATTGGACTCA GACAAGAGAA TTACAGCAGC CCAAGCCCTC GCACATGCCT 
ACTTTGCTCA GTACCATGAT CCAGATGATG AACCAGTGGC TGATCCTTAC GATCAGTCCT 
TTGAAAGCAG GGACCTCCTT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_013973497.1
CDS	391..1314
Translation	MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGADLLKKISSESLSTCWRRCLYWTQTRELQQPKPSHMPTLLSTMIQMMNQWLILTISPLKAGTSL

Target ORF information:

RefSeq Version	XM_014118022.2
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_014118022.2

ORF Insert Sequence:

ATGTCTCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ATAAGACAAT CTGGGAGGTG 
CCCGAGCGTT ACCAGAACCT GTCCCCGGTG GGCTCCGGCG CCTACGGCTC CGTGTGTGCT 
GCTTTTGACA CAAAAACTGG GTTACGTGTG GCAGTCAAGA AGCTCTCCAG ACCATTTCAG 
TCCATTATTC ATGCCAAAAG GACCTACAGA GAACTGCGGT TACTGAAACA TATGAAACAT 
GAAAATGTGA TTGGTCTCTT GGATGTTTTT ACACCTGCAA GGTCTCTGGA GGAATTCAAT 
GATGTGTATC TGGTGACCCA TCTTATGGGA GCAGATCTGA ACAACATTGT GAAATGTCAG 
AAGCTTACGG ATGACCATGT TCAGTTCCTT ATCTACCAAA TTCTCCGAGG TCTCAAGTAT 
ATACATTCAG CTGACATAAT TCACAGGGAC CTAAAACCTA GCAATCTAGC TGTGAATGAA 
GACTGTGAGC TGAAGATCTT GGACTTTGGA CTGGCCCGAC ATACAGATGA TGAAATGACA 
GGCTATGTGG CTACCAGGTG GTACAGGGCT CCTGAGATAA TGCTGAACTG GATGCATTAC 
AACCAGACAG TTGATATTTG GTCAGTGGGA TGCATAATGG CCGAACTGTT GACTGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTGAT CAGTTGAAGC TCATTTTAAG ACTCGTTGGA 
ACCCCAGGGG CTGATCTTTT GAAGAAAATC TCCTCAGAGT CTCTGTCGAC TTGCTGGAGA 
AGATGCTTGT ATTGGACTCA GACAAGAGAA TTACAGCAGC CCAAGCCCTC GCACATGCCT 
ACTTTGCTCA GTACCATGAT CCAGATGATG AACCAGTGGC TGATCCTTAC GATCAGTCCT 
TTGAAAGCAG GGACCTCCTT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAPK14 ( XM_014118022.1 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_013973497.1 Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), transcript variant X2, mRNA.

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CloneID	OCe39318
Clone ID Related Accession (Same CDS sequence)	XM_014118022.2 , XM_014118022.1
Accession Version	XM_014118022.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 924bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	mitogen-activated protein kinase 14 isoform X2
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726081.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ATAAGACAAT CTGGGAGGTG 
CCCGAGCGTT ACCAGAACCT GTCCCCGGTG GGCTCCGGCG CCTACGGCTC CGTGTGTGCT 
GCTTTTGACA CAAAAACTGG GTTACGTGTG GCAGTCAAGA AGCTCTCCAG ACCATTTCAG 
TCCATTATTC ATGCCAAAAG GACCTACAGA GAACTGCGGT TACTGAAACA TATGAAACAT 
GAAAATGTGA TTGGTCTCTT GGATGTTTTT ACACCTGCAA GGTCTCTGGA GGAATTCAAT 
GATGTGTATC TGGTGACCCA TCTTATGGGA GCAGATCTGA ACAACATTGT GAAATGTCAG 
AAGCTTACGG ATGACCATGT TCAGTTCCTT ATCTACCAAA TTCTCCGAGG TCTCAAGTAT 
ATACATTCAG CTGACATAAT TCACAGGGAC CTAAAACCTA GCAATCTAGC TGTGAATGAA 
GACTGTGAGC TGAAGATCTT GGACTTTGGA CTGGCCCGAC ATACAGATGA TGAAATGACA 
GGCTATGTGG CTACCAGGTG GTACAGGGCT CCTGAGATAA TGCTGAACTG GATGCATTAC 
AACCAGACAG TTGATATTTG GTCAGTGGGA TGCATAATGG CCGAACTGTT GACTGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTGAT CAGTTGAAGC TCATTTTAAG ACTCGTTGGA 
ACCCCAGGGG CTGATCTTTT GAAGAAAATC TCCTCAGAGT CTCTGTCGAC TTGCTGGAGA 
AGATGCTTGT ATTGGACTCA GACAAGAGAA TTACAGCAGC CCAAGCCCTC GCACATGCCT 
ACTTTGCTCA GTACCATGAT CCAGATGATG AACCAGTGGC TGATCCTTAC GATCAGTCCT 
TTGAAAGCAG GGACCTCCTT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_013973497.1
CDS	410..1333
Translation	MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGADLLKKISSESLSTCWRRCLYWTQTRELQQPKPSHMPTLLSTMIQMMNQWLILTISPLKAGTSL

Target ORF information:

RefSeq Version	XM_014118022.1
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris mitogen-activated protein kinase 14 (MAPK14), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_014118022.1

ORF Insert Sequence:

ATGTCTCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ATAAGACAAT CTGGGAGGTG 
CCCGAGCGTT ACCAGAACCT GTCCCCGGTG GGCTCCGGCG CCTACGGCTC CGTGTGTGCT 
GCTTTTGACA CAAAAACTGG GTTACGTGTG GCAGTCAAGA AGCTCTCCAG ACCATTTCAG 
TCCATTATTC ATGCCAAAAG GACCTACAGA GAACTGCGGT TACTGAAACA TATGAAACAT 
GAAAATGTGA TTGGTCTCTT GGATGTTTTT ACACCTGCAA GGTCTCTGGA GGAATTCAAT 
GATGTGTATC TGGTGACCCA TCTTATGGGA GCAGATCTGA ACAACATTGT GAAATGTCAG 
AAGCTTACGG ATGACCATGT TCAGTTCCTT ATCTACCAAA TTCTCCGAGG TCTCAAGTAT 
ATACATTCAG CTGACATAAT TCACAGGGAC CTAAAACCTA GCAATCTAGC TGTGAATGAA 
GACTGTGAGC TGAAGATCTT GGACTTTGGA CTGGCCCGAC ATACAGATGA TGAAATGACA 
GGCTATGTGG CTACCAGGTG GTACAGGGCT CCTGAGATAA TGCTGAACTG GATGCATTAC 
AACCAGACAG TTGATATTTG GTCAGTGGGA TGCATAATGG CCGAACTGTT GACTGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTGAT CAGTTGAAGC TCATTTTAAG ACTCGTTGGA 
ACCCCAGGGG CTGATCTTTT GAAGAAAATC TCCTCAGAGT CTCTGTCGAC TTGCTGGAGA 
AGATGCTTGT ATTGGACTCA GACAAGAGAA TTACAGCAGC CCAAGCCCTC GCACATGCCT 
ACTTTGCTCA GTACCATGAT CCAGATGATG AACCAGTGGC TGATCCTTAC GATCAGTCCT 
TTGAAAGCAG GGACCTCCTT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of Src signal transduction pathways in scatter factor-mediated cellular protection.
The Journal of biological chemistry284(12)7561-77(2009 Mar)
Fan S,Meng Q,Laterra JJ,Rosen EM

Bcl-2 Phosphorylation by p38 MAPK: identification of target sites and biologic consequences.
The Journal of biological chemistry281(30)21353-61(2006 Jul)
De Chiara G,Marcocci ME,Torcia M,Lucibello M,Rosini P,Bonini P,Higashimoto Y,Damonte G,Armirotti A,Amodei S,Palamara AT,Russo T,Garaci E,Cozzolino F

Rho/ROCK-dependent pseudopodial protrusion and cellular blebbing are regulated by p38 MAPK in tumour cells exhibiting autocrine c-Met activation.
Biology of the cell98(6)337-51(2006 Jun)
Jia Z,Vadnais J,Lu ML,No?l J,Nabi IR

A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase.
The Journal of cell biology147(6)1129-36(1999 Dec)
Blanco-Aparicio C,Torres J,Pulido R

p38 mitogen-activated protein kinase expression and activation in smooth muscle.
The American journal of physiology275(2 Pt 1)C527-34(1998 Aug)
Hedges JC,Yamboliev IA,Ngo M,Horowitz B,Adam LP,Gerthoffer WT

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MAPK14 cDNA ORF clone, Canis lupus familiaris(Dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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電話

FAX

オンラインフォーム