Gene Symbol | pmk-1 |
Entrez Gene ID | 191743 |
Full Name | Mitogen-activated protein kinase pmk-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » pmk-1 cDNA ORF clone
Gene Symbol | pmk-1 |
Entrez Gene ID | 191743 |
Full Name | Mitogen-activated protein kinase pmk-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_068964.4 | NP_501365.1 | Mitogen-activated protein kinase pmk-1 |
NM_068964.3 | NP_501365.1 | Mitogen-activated protein kinase pmk-1 |
Homo sapiens (human) | MAPK14 | NP_001306.1 |
Saccharomyces cerevisiae (baker's yeast) | HOG1 | NP_013214.1 |
Neurospora crassa | NCU07024 | XP_962163.2 |
Canis lupus familiaris (dog) | MAPK14 | NP_001003206.1 |
Rattus norvegicus (Norway rat) | Mapk14 | NP_112282.2 |
Kluyveromyces lactis | KLLA0F20053g | XP_455981.1 |
Eremothecium gossypii | AGOS_AGR048C | NP_986713.1 |
Bos taurus (cattle) | MAPK14 | NP_001095644.1 |
Drosophila melanogaster (fruit fly) | Mpk2 | NP_001163711.1 |
Caenorhabditis elegans (roundworm) | pmk-1 | NP_501365.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01822 | XP_003714838.1 |
Oryza sativa (rice) | Os03g0285800 | NP_001049770.1 |
Xenopus tropicalis (tropical clawed frog) | mapk14 | NP_001005824.1 |
LOC718976 | XP_001112423.2 | |
Mus musculus (house mouse) | Mapk14 | NP_001161980.1 |
Gallus gallus (chicken) | MAPK14 | XP_001232616.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012148 | XP_320380.4 |
Schizosaccharomyces pombe (fission yeast) | sty1 | NP_592843.1 |
Pan troglodytes (chimpanzee) | MAPK14 | NP_001009065.1 |
Danio rerio (zebrafish) | mapk14a | NP_571797.1 |
Drosophila melanogaster (fruit fly) | p38b | NP_477361.1 |
Arabidopsis thaliana (thale cress) | MPK3 | NP_190150.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The authors determined that the GATA transcription factor ELT-2 and the p38 MAP kinase PMK-1 are necessary for animals to successfully recover from an acute Pseudomonas aeruginosa infection.
Title: Role of GATA transcription factor ELT-2 and p38 MAPK PMK-1 in recovery from acute P. aeruginosa infection in C. elegans.
The authors used RNAi to knock down p38 MAPK (pmk-1) expression. C. elegans MAPK mutants are hypersusceptible to mycobacterial infection and pathogenic mycobacteria inhibit MAPK-mediated protection through the MAPK phosphatase gene.
Title: The Caenorhabditis elegans p38 MAPK Gene plays a key role in protection from mycobacteria.
Whereas PMK-2 functions redundantly with PMK-1 in the nervous system to regulate neuronal development and behavioral responses to pathogenic bacteria, the miR-58, miR-80, miR-81, and miR-82 microRNAs function redundantly to destabilize pmk-2 mRNA
Title: Tissue expression pattern of PMK-2 p38 MAPK is established by the miR-58 family in C. elegans.
PMK-1 plays an important protective role in silver nanoparticle-induced oxidative DNA damage-repair.
Title: Effects of silver nanoparticles on oxidative DNA damage-repair as a function of p38 MAPK status: a comparative approach using human Jurkat T cells and the nematode Caenorhabditis elegans.
C. elegans MOM-4 is required for the resistance of C. elegans to a P. aeruginosa infection
Title: Caenorhabditis elegans mom-4 is required for the activation of the p38 MAPK signaling pathway in the response to Pseudomonas aeruginosa infection.
The following pmk-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pmk-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa343282 | |
Clone ID Related Accession (Same CDS sequence) | NM_068964.4 , NM_068964.3 | |
Accession Version | NM_068964.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Mitogen-activated protein kinase pmk-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_068964.3. |
1 | ATGTTTCCAC AGACAACAAT GGATCATATA CTTCATCCGA CTCCACGAGA AGGATACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_501365.1 |
CDS | 13..1146 |
Translation |
Target ORF information:
Target ORF information:
|
NM_068964.4 |
1 | ATGTTTCCAC AGACAACAAT GGATCATATA CTTCATCCGA CTCCACGAGA AGGATACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343282 | |
Clone ID Related Accession (Same CDS sequence) | NM_068964.4 , NM_068964.3 | |
Accession Version | NM_068964.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Mitogen-activated protein kinase pmk-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_068964.2. COMPLETENESS: incomplete on both ends. |
1 | ATGTTTCCAC AGACAACAAT GGATCATATA CTTCATCCGA CTCCACGAGA AGGATACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_501365.1 |
CDS | 1..1134 |
Translation |
Target ORF information:
Target ORF information:
|
NM_068964.3 |
1 | ATGTTTCCAC AGACAACAAT GGATCATATA CTTCATCCGA CTCCACGAGA AGGATACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |