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Homo sapiens (human)

Browse by Letter Index, Genomic Locus


Defective AMN causes hereditary megaloblastic anemia 1 Defective GIF causes intrinsic factor deficiency
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective MUT causes methylmalonic aciduria mut type
Defective CD320 causes methylmalonic aciduria Binding and entry of HIV virion
Pausing and recovery of Tat-mediated HIV elongation Synthesis and processing of ENV and VPU
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Vif-mediated degradation of APOBEC3G
The role of Nef in HIV-1 replication and disease pathogenesis Nef Mediated CD4 Down-regulation
Nef Mediated CD8 Down-regulation Vpu mediated degradation of CD4
Influenza Life Cycle Entry of Influenza Virion into Host Cell via Endocytosis
Influenza Viral RNA Transcription and Replication Export of Viral Ribonucleoproteins from Nucleus
Assembly of Viral Components at the Budding Site Inhibition of Host mRNA Processing and RNA Silencing
Inhibition of PKR ROS, RNS production in phagocytes
Mtb iron assimilation by chelation Uptake and actions of bacterial toxins
Toxicity of botulinum toxin type A (BoNT/A) Uptake and function of anthrax toxins
TLR3 deficiency - HSE UNC93B1 deficiency - HSE
TRAF3 deficiency - HSE IKBKB deficiency causes SCID
Immune System Clathrin derived vesicle budding
Golgi Associated Vesicle Biogenesis Gap junction assembly
Gap junction degradation Bicarbonate transporters
Organic anion transporters Proton/oligopeptide cotransporters
Metal ion SLC transporters Zinc efflux and compartmentalization by the SLC30 family
Rhesus glycoproteins mediate ammonium transport. Transport of organic anions
Vasopressin regulates renal water homeostasis via Aquaporins TRP channels
Glucose metabolism Glycogen breakdown (glycogenolysis)
Fructose biosynthesis 5-Phosphoribose 1-diphosphate biosynthesis
Hyaluronan uptake and degradation Keratan sulfate biosynthesis
Trafficking of dietary sterols Lipoprotein metabolism
Fatty acid, triacylglycerol, and ketone body metabolism Beta oxidation of hexanoyl-CoA to butanoyl-CoA
Propionyl-CoA catabolism Ketone body metabolism
Alpha-oxidation of phytanate Beta-oxidation of very long chain fatty acids
NADPH regeneration Cholesterol biosynthesis
Androgen biosynthesis Acyl chain remodeling of DAG and TAG
Synthesis of PE Synthesis of PC
Synthesis of Leukotrienes (LT) and Eoxins (EX) Synthesis of 5-eicosatetraenoic acids
Glycosphingolipid metabolism Free fatty acids regulate insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon signaling in metabolic regulation
PKA-mediated phosphorylation of key metabolic factors Insulin effects increased synthesis of Xylulose-5-Phosphate
Metabolism of nitric oxide Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate Formation of ATP by chemiosmotic coupling
Purine metabolism Purine salvage
Pyrimidine biosynthesis Pyrimidine salvage reactions
Phosphate bond hydrolysis by NUDT proteins Vitamin B1 (thiamin) metabolism
Metabolism of folate and pterines Amino acid synthesis and interconversion (transamination)
Histidine catabolism Carnitine synthesis
Interconversion of polyamines Methionine salvage pathway
Regulation of ornithine decarboxylase (ODC) Glyoxylate metabolism and glycine degradation
Cytochrome P450 - arranged by substrate type Amine Oxidase reactions
Ethanol oxidation Cytosolic sulfonation of small molecules
Acetylation Glutathione synthesis and recycling
Conjugation of benzoate with glycine Cell-Cell communication
Tight junction interactions Assembly of collagen fibrils and other multimeric structures
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