gmppb cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	gmppb
Entrez Gene ID	445097
Full Name	GDP-mannose pyrophosphorylase B
Synonyms	cb1066,fc79b10,gmppl,wu:fc79b10,zgc:92026
General protein information	Preferred Names GDP-mannose pyrophosphorylase B Names mannose-1-phosphate guanyltransferase beta GTP-mannose-1-phosphate guanylyltransferase beta
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003491.2	NP_001003491.2	mannose-1-phosphate guanyltransferase beta

Pathways from BioSystems

Homologies

Homo sapiens (human)	GMPPB	NP_037466.2
	GMPPB	XP_001106890.1
Danio rerio (zebrafish)	gmppb	NP_001003491.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001299	XP_001689367.1
Caenorhabditis elegans (roundworm)	tag-335	NP_502333.2
Kluyveromyces lactis	KLLA0E05435g	XP_454190.1
Oryza sativa (rice)	Os01g0847200	NP_001044795.1
Canis lupus familiaris (dog)	GMPPB	XP_003639816.1
Neurospora crassa	NCU11213	XP_958811.1
Arabidopsis thaliana (thale cress)	CYT1	NP_181507.1
Gallus gallus (chicken)	GMPPB	XP_004944488.1
Eremothecium gossypii	AGOS_AFR599W	NP_986146.1
Magnaporthe oryzae (rice blast fungus)	MGG_01288	XP_003714211.1
Rattus norvegicus (Norway rat)	Gmppb	NP_001102251.1
Drosophila melanogaster (fruit fly)	CG1129	NP_649498.1
Saccharomyces cerevisiae (baker's yeast)	PSA1	NP_010228.1
Oryza sativa (rice)	Os03g0268400	NP_001049673.1
Pan troglodytes (chimpanzee)	GMPPB	XP_516466.1
Bos taurus (cattle)	GMPPB	NP_001039633.1
Mus musculus (house mouse)	Gmppb	NP_808578.1
Schizosaccharomyces pombe (fission yeast)	mpg1	NP_588405.1
Xenopus tropicalis (tropical clawed frog)	gmppb	NP_001008434.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

trappc11 is required for protein glycosylation in zebrafish and humans.
DeRossi C, Vacaru A, Rafiq R, Cinaroglu A, Imrie D, Nayar S, Baryshnikova A, Milev MP, Stanga D, Kadakia D, Gao N, Chu J, Freeze HH, Lehrman MA, Sacher M, Sadler KC
Molecular biology of the cell27(8)1220-34(2016 Apr)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Mutations in GDP-mannose pyrophosphorylase B cause congenital and limb-girdle muscular dystrophies associated with hypoglycosylation of ?-dystroglycan.
Carss KJ, Stevens E, Foley AR, Cirak S, Riemersma M, Torelli S, Hoischen A, Willer T, van Scherpenzeel M, Moore SA, Messina S, Bertini E, B?nnemann CG, Abdenur JE, Grosmann CM, Kesari A, Punetha J, Quinlivan R, Waddell LB, Young HK, Wraige E, Yau S, Brodd L, Feng L, Sewry C, MacArthur DG, North KN, Hoffman E, Stemple DL, Hurles ME, van Bokhoven H, Campbell KP, Lefeber DJ, , Lin YY, Muntoni F
American journal of human genetics93(1)29-41(2013 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following gmppb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the gmppb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa00294	NM_001003491.2 Latest version!	Danio rerio GDP-mannose pyrophosphorylase B (gmppb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

gmppb ( NM_001003491.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001003491.2 Danio rerio GDP-mannose pyrophosphorylase B (gmppb), mRNA.

Price & Availability↑

CloneID	ODa00294
Clone ID Related Accession (Same CDS sequence)	NM_001003491.2
Accession Version	NM_001003491.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-26
Organism	Danio rerio(zebrafish)
Product	mannose-1-phosphate guanyltransferase beta
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH443649.1, EH432499.1, EH541442.1 and EH459927.1. On Dec 25, 2013 this sequence version replaced NM_001003491.1. ##Evidence-Data-START## Transcript exon combination :: BC078357.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGAAAGCTC TGATTCTTGT CGGTGGCTAT GGCACACGAT TACGGCCGCT CACCCTCACT 
GTGCCCAAAC CACTCGTTGA GTTCTGCAAC AAACCCATTC TGCTGCATCA GGTGGAGGCT 
TTGGTCAAGG CTGGAGTCCG TCATGTCATC CTTGCTGTGA GTTACATGTC TGAGCTATTG 
GAGCGAGAGA TGAGAGCCCA GGAGCAAAGG CTTGGAATAA AGATCTCCCT CTCACATGAA 
AAAGAGCCTC TAGGAACCGC TGGTCCTCTG GCTTTGGCTC GTGAGCTGCT GACCGACAAC 
CAGGAGCCCT TTTTTGTTCT CAATAGTGAT GTCATCTGCG ATTTCCCCTT CGACGACATG 
CTCAAGTTCC ACCAGCAGCA CGGCAGAGAG GGCACCATTG TTGTGACAAA AGTTGAAGAA 
CCGTCTAAAT ATGGTGTGGT GGTTTATGAA GGGGACAGCG GGCGAATACA CCGCTTCGTT 
GAGAAACCGC AAGTGTTTGT CTCCAACAAA ATCAATGCGG GGATGTACAT CTTCAGTCCT 
GCCATGCTGA GAAGAATCCA GTTGCAACCC ACTTCCATAG AGAAGGAAAT ATTTCCTGTC 
ATGGCAGAGG AGGGACAGCT GTATGCCATG GAGCTGCAAG GTTTCTGGAT GGACATTGGT 
CAGCCTAAAG ACTTCCTGAC GGGCATGTGC ATGTACCTGC AATCTGTACG GCAGCAGGCC 
CCTGAGAGGC TCCGCGCTGG ACCCGGCTTT CTTGGAAATG TTCTTGTGGA CCCAACAGCA 
GTGATTGGGC AGAACTGCAC CATTGGCCCA AATGTGACGA TTGGAGCCGG GGTGGTTTTG 
GAGGACGGGG TGAGAGTGAA GCGCTGTACC ATCCTGAAGG GGGCACACAT ACGCTCCCAC 
TCCTGGCTGG AGTCCTGCAT CGTGGGATGG AGCTCCTCAG TTGGGCAGTG GGTGCGAATG 
GAGAACGTTA CGGTTCTGGG TGAAGATGTG ATTGTGAATG ATGAACTCTA CATCAACGGA 
GCCAACGTTC TGCCTCATAA ATCTATCACA GACTCTGTTC CTGAACCACG AATCATCATG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003491.2
CDS	214..1296
Translation	MKALILVGGYGTRLRPLTLTVPKPLVEFCNKPILLHQVEALVKAGVRHVILAVSYMSELLEREMRAQEQRLGIKISLSHEKEPLGTAGPLALARELLTDNQEPFFVLNSDVICDFPFDDMLKFHQQHGREGTIVVTKVEEPSKYGVVVYEGDSGRIHRFVEKPQVFVSNKINAGMYIFSPAMLRRIQLQPTSIEKEIFPVMAEEGQLYAMELQGFWMDIGQPKDFLTGMCMYLQSVRQQAPERLRAGPGFLGNVLVDPTAVIGQNCTIGPNVTIGAGVVLEDGVRVKRCTILKGAHIRSHSWLESCIVGWSSSVGQWVRMENVTVLGEDVIVNDELYINGANVLPHKSITDSVPEPRIIM

Target ORF information:

RefSeq Version	NM_001003491.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio GDP-mannose pyrophosphorylase B (gmppb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003491.2

ORF Insert Sequence:

ATGAAAGCTC TGATTCTTGT CGGTGGCTAT GGCACACGAT TACGGCCGCT CACCCTCACT 
GTGCCCAAAC CACTCGTTGA GTTCTGCAAC AAACCCATTC TGCTGCATCA GGTGGAGGCT 
TTGGTCAAGG CTGGAGTCCG TCATGTCATC CTTGCTGTGA GTTACATGTC TGAGCTATTG 
GAGCGAGAGA TGAGAGCCCA GGAGCAAAGG CTTGGAATAA AGATCTCCCT CTCACATGAA 
AAAGAGCCTC TAGGAACCGC TGGTCCTCTG GCTTTGGCTC GTGAGCTGCT GACCGACAAC 
CAGGAGCCCT TTTTTGTTCT CAATAGTGAT GTCATCTGCG ATTTCCCCTT CGACGACATG 
CTCAAGTTCC ACCAGCAGCA CGGCAGAGAG GGCACCATTG TTGTGACAAA AGTTGAAGAA 
CCGTCTAAAT ATGGTGTGGT GGTTTATGAA GGGGACAGCG GGCGAATACA CCGCTTCGTT 
GAGAAACCGC AAGTGTTTGT CTCCAACAAA ATCAATGCGG GGATGTACAT CTTCAGTCCT 
GCCATGCTGA GAAGAATCCA GTTGCAACCC ACTTCCATAG AGAAGGAAAT ATTTCCTGTC 
ATGGCAGAGG AGGGACAGCT GTATGCCATG GAGCTGCAAG GTTTCTGGAT GGACATTGGT 
CAGCCTAAAG ACTTCCTGAC GGGCATGTGC ATGTACCTGC AATCTGTACG GCAGCAGGCC 
CCTGAGAGGC TCCGCGCTGG ACCCGGCTTT CTTGGAAATG TTCTTGTGGA CCCAACAGCA 
GTGATTGGGC AGAACTGCAC CATTGGCCCA AATGTGACGA TTGGAGCCGG GGTGGTTTTG 
GAGGACGGGG TGAGAGTGAA GCGCTGTACC ATCCTGAAGG GGGCACACAT ACGCTCCCAC 
TCCTGGCTGG AGTCCTGCAT CGTGGGATGG AGCTCCTCAG TTGGGCAGTG GGTGCGAATG 
GAGAACGTTA CGGTTCTGGG TGAAGATGTG ATTGTGAATG ATGAACTCTA CATCAACGGA 
GCCAACGTTC TGCCTCATAA ATCTATCACA GACTCTGTTC CTGAACCACG AATCATCATG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

trappc11 is required for protein glycosylation in zebrafish and humans.
Molecular biology of the cell27(8)1220-34(2016 Apr)
DeRossi C,Vacaru A,Rafiq R,Cinaroglu A,Imrie D,Nayar S,Baryshnikova A,Milev MP,Stanga D,Kadakia D,Gao N,Chu J,Freeze HH,Lehrman MA,Sacher M,Sadler KC

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Mutations in GDP-mannose pyrophosphorylase B cause congenital and limb-girdle muscular dystrophies associated with hypoglycosylation of ?-dystroglycan.
American journal of human genetics93(1)29-41(2013 Jul)
Carss KJ,Stevens E,Foley AR,Cirak S,Riemersma M,Torelli S,Hoischen A,Willer T,van Scherpenzeel M,Moore SA,Messina S,Bertini E,B?nnemann CG,Abdenur JE,Grosmann CM,Kesari A,Punetha J,Quinlivan R,Waddell LB,Young HK,Wraige E,Yau S,Brodd L,Feng L,Sewry C,MacArthur DG,North KN,Hoffman E,Stemple DL,Hurles ME,van Bokhoven H,Campbell KP,Lefeber DJ,,Lin YY,Muntoni F

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gmppb cDNA ORF clone, Danio rerio(zebrafish)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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