Gene Symbol | apl-1 |
Entrez Gene ID | 180783 |
Full Name | Amyloid-beta-like protein |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » apl-1 cDNA ORF clone
Gene Symbol | apl-1 |
Entrez Gene ID | 180783 |
Full Name | Amyloid-beta-like protein |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_076469.5 | NP_508870.3 | Amyloid-beta-like protein |
NM_076470.4 | NP_508871.1 | Amyloid-beta-like protein |
NM_076469.6 | NP_508870.3 | Amyloid-beta-like protein |
NM_076470.6 | NP_508871.1 | Amyloid-beta-like protein |
Homo sapiens (human) | APP | NP_000475.1 |
Bos taurus (cattle) | APP | NP_001070264.1 |
Pan troglodytes (chimpanzee) | APP | NP_001013036.1 |
Rattus norvegicus (Norway rat) | App | NP_062161.1 |
Caenorhabditis elegans (roundworm) | apl-1 | NP_508870.3 |
Danio rerio (zebrafish) | appb | NP_690842.1 |
Canis lupus familiaris (dog) | APP | NP_001006601.1 |
Xenopus tropicalis (tropical clawed frog) | app | NP_001005698.1 |
APP | XP_002803216.1 | |
Mus musculus (house mouse) | App | NP_001185752.1 |
Gallus gallus (chicken) | APP | NP_989639.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data indicate that APL1-D2 binds Cu(I) and Cu(II) too weakly to sustain catalysis which suggests that it plays no significant role in copper handling in C. elegans.
Title: Quantification of copper binding to amyloid precursor protein domain 2 and its Caenorhabditis elegans ortholog. Implications for biological function.
present hypothetical models as to how sAPL-1 signaling influences metabolic and developmental pathways.
Title: The secreted Alzheimer-related amyloid precursor protein fragment has an essential role in C. elegans.
Pan-neuronal expression of APL-1, the Caenorhabditis elegans ortholog of APP, disrupts several behaviors, such as olfactory and gustatory learning behavior and touch habituation.
Title: Pan-neuronal expression of APL-1, an APP-related protein, disrupts olfactory, gustatory, and touch plasticity in Caenorhabditis elegans.
signaling of the released APL-1 fragment modulates multiple metabolic states and that APL-1 is required throughout development.
Title: APL-1, the Alzheimer's Amyloid precursor protein in Caenorhabditis elegans, modulates multiple metabolic pathways throughout development.
Cholesterol and lrp-1 are involved in the regulation of synaptic transmission, similar to apl-1.
Title: Regulation of neuronal APL-1 expression by cholesterol starvation.
The following apl-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the apl-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa349439 | |
Clone ID Related Accession (Same CDS sequence) | NM_076469.5 , NM_076469.6 | |
Accession Version | NM_076469.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2061bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Amyloid-beta-like protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_076469.4. COMPLETENESS: incomplete on both ends. |
1 | ATGACGGTGG GTAAACTAAT GATTGGCTTA CTTATACCGA TTCTTGTCGC CACAGTTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_508870.3 |
CDS | 1..2061 |
Translation |
Target ORF information:
Target ORF information:
|
NM_076469.5 |
1 | ATGACGGTGG GTAAACTAAT GATTGGCTTA CTTATACCGA TTCTTGTCGC CACAGTTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349439 | |
Clone ID Related Accession (Same CDS sequence) | NM_076469.5 , NM_076469.6 | |
Accession Version | NM_076469.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2061bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Amyloid-beta-like protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Sep 4, 2019 this sequence version replaced NM_076469.5. |
1 | ATGACGGTGG GTAAACTAAT GATTGGCTTA CTTATACCGA TTCTTGTCGC CACAGTTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_508870.3 |
CDS | 3..2063 |
Translation |
Target ORF information:
Target ORF information:
|
NM_076469.6 |
1 | ATGACGGTGG GTAAACTAAT GATTGGCTTA CTTATACCGA TTCTTGTCGC CACAGTTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349440 | |
Clone ID Related Accession (Same CDS sequence) | NM_076470.4 , NM_076470.6 | |
Accession Version | NM_076470.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Amyloid-beta-like protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_076470.3. COMPLETENESS: incomplete on both ends. |
1 | ATGACGGTGG GTAAACTAAT GATTGGCTTA CTTATACCGA TTCTTGTCGC CACAGTTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_508871.1 |
CDS | 1..2055 |
Translation |
Target ORF information:
Target ORF information:
|
NM_076470.4 |
1 | ATGACGGTGG GTAAACTAAT GATTGGCTTA CTTATACCGA TTCTTGTCGC CACAGTTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349440 | |
Clone ID Related Accession (Same CDS sequence) | NM_076470.4 , NM_076470.6 | |
Accession Version | NM_076470.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Amyloid-beta-like protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Oct 18, 2019 this sequence version replaced NM_076470.5. |
1 | ATGACGGTGG GTAAACTAAT GATTGGCTTA CTTATACCGA TTCTTGTCGC CACAGTTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_508871.1 |
CDS | 3..2057 |
Translation |
Target ORF information:
Target ORF information:
|
NM_076470.6 |
1 | ATGACGGTGG GTAAACTAAT GATTGGCTTA CTTATACCGA TTCTTGTCGC CACAGTTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |